TIZANIDINE belongs to the class of drugs called skeletal muscle relaxants used to treat muscle spasticity (muscles become heavy, stiff, and difficult to move) and relieve discomfort due to acute, painful musculoskeletal conditions like stiffness, tension, rigidity, and muscle spasms. Muscle spasticity is a condition in which muscles become stiff, contract, or cause involuntary spasm, making it difficult to move, walk, or talk, which can sometimes be painful and uncomfortable.
TIZANIDINE contains Tizanidine that works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms.
Take TIZANIDINE with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience drowsiness, dizziness, dry mouth, flu-like symptoms, vomiting, constipation, nervousness, sore throat, runny nose, blurred vision, or weakness. Most of these side effects of TIZANIDINE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to TIZANIDINE or any other medicines, please tell your doctor. TIZANIDINE is not recommended for children as the safety and effectiveness were not established. Please consult a doctor if you are pregnant or breastfeeding before taking TIZANIDINE. Do not consume alcohol with TIZANIDINE as it may increase the risk of adverse effects. Avoid taking TIZANIDINE with fluvoxamine and ciprofloxacin as it may cause adverse effects such as slurred speech, dizziness, weakness, confusion, low blood pressure, or drowsiness. You are advised not to take more than 3 doses of TIZANIDINE in a single day as too much of TIZANIDINE may cause liver damage. If you have low blood pressure, liver or kidney diseases, inform your doctor before taking TIZANIDINE.
Muscle spasticity
TIZANIDINE contains Tizanidine used to treat muscle spasms. It works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms.
If you are allergic to TIZANIDINE or any other medicines, please tell your doctor. Take TIZANIDINE either with food or without food but in the same way, each time as switching between them may reduce the effectiveness of TIZANIDINE or increase adverse effects. TIZANIDINE is not recommended for children as safety and effectiveness were not established. Please consult a doctor if you are pregnant or breastfeeding before taking TIZANIDINE. Do not consume alcohol with TIZANIDINE as it may increase the risk of adverse effects. Avoid taking TIZANIDINE with fluvoxamine and ciprofloxacin as it may cause adverse effects such as slurred speech, dizziness, weakness, confusion, low blood pressure, or drowsiness. You are advised not to take more than 3 doses of TIZANIDINE in a single day as too much of TIZANIDINE may cause liver damage. If you have low blood pressure, liver or kidney diseases, inform your doctor before taking TIZANIDINE.
Drug-Drug Interactions: TIZANIDINE may have interaction with antidepressants (escitalopram, duloxetine, sertraline, fluvoxamine), anticonvulsants (pregabalin, topiramate), anti-allergic drugs (diphenhydramine, cetirizine), pain relievers (acetaminophen + hydrocodone), an anti-anxiety drug (alprazolam), sedative-hypnotic drug (zolpidem), bronchodilator (albuterol), antibiotic (ciprofloxacin).
Drug-Food Interactions: TIZANIDINE may interact with caffeine. Therefore, avoid intake of caffeine with TIZANIDINE as it may cause low blood pressure and dizziness. Also, avoid intake of alcohol with TIZANIDINE as it may increase the risk of adverse effects.
Drug-Disease Interactions: If you have low blood pressure, liver or kidney diseases, inform your doctor before taking TIZANIDINE.
You are recommended to avoid alcohol consumption with TIZANIDINE as it may increase the risk of adverse effects.
TIZANIDINE is a category C pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. However, please consult a doctor if you are pregnant.
It is unknown whether TIZANIDINE is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. TIZANIDINE is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.
TIZANIDINE may cause drowsiness, dizziness, or vision problems in some people. Therefore, avoid driving if you feel any of these symptoms after taking TIZANIDINE.
Take TIZANIDINE with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Take TIZANIDINE with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
TIZANIDINE is not recommended for children as the safety and effectiveness were not established.
Regular blood tests are recommended to monitor liver functioning while taking TIZANIDINE.
Muscle spasticity is a condition in which muscles become stiff, contract, or cause involuntary spasm making it difficult to move, walk or talk, which can be painful and uncomfortable sometimes. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasticity. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty in moving, pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection, and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasticity. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Whereas, exercise helps in muscle stretching to be less likely to spasm, tear and sprain.