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compositionComposition:TIZANIDINE-2MG
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Tizan 2 Tablet is a skeletal muscle relaxant used to treat muscle spasticity caused by spinal cord injuries or neurological conditions such as multiple sclerosis or stroke. It also helps relieve muscle pain, cramps, and stiffness, improving movement and daily comfort.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

TIZANIDINE-2MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tizan 2 Tablet

Tizan 2 Tablet is an oral prescription medication used to treat muscle spasticity, stiffness, and sudden muscle spasms. It is commonly prescribed for individuals dealing with long-term neurological conditions such as multiple sclerosis or spinal cord injuries. By relaxing tense muscles, this medication helps improve daily comfort and physical mobility.

Your doctor will determine how often you should take this medicine based on your specific needs, often aligning doses with times when you require the most relief. To ensure it works consistently, you must take it the same way every time, either always with food or always on an empty stomach. Combining this treatment with gentle physical therapy, regular stretching routines, and drinking plenty of water can significantly improve your physical recovery and overall comfort levels.

While taking this medicine, you may experience some common side effects such as dry mouth, drowsiness, or dizziness. Most of these are mild, but you should contact your doctor immediately if you notice more serious signs like a very slow heart rate, fainting, or signs of liver damage, such as yellowing of your skin or eyes.

Before you begin taking this medication, tell your doctor if you have a history of kidney disease, liver issues, or low blood pressure. Do not take this medicine if you are currently taking certain strong medications like fluvoxamine or ciprofloxacin, as this combination can lead to dangerously high levels of the drug in your body.

This medicine can interact with alcohol, smoking, and other drugs that cause drowsiness, which can make you feel excessively tired, slow your breathing, or lower your blood pressure. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to discuss if this medication is appropriate for you.

Uses of Tizan 2 Tablet

Tizan 2 Tablet is used to treat muscle spasticity and muscle spasms associated with neurological and musculoskeletal conditions. The detailed uses of Tizan 2 Tablet are as follows:

  • Muscle spasticity: Helps manage increased muscle tone, stiffness, and muscle tightness associated with long-term neurological conditions like multiple sclerosis.
  • Spinal cord injuries: Relieves severe muscle spasms and cramping resulting from damage to the spinal cord, allowing for easier movement and therapy.
  • Acute muscle spasms: Sometimes prescribed to relieve severe, temporary muscle tightness and pain associated with musculoskeletal injuries.

Key Benefits

Tizan 2 Tablet helps relieve muscle stiffness, spasms, and cramping, allowing for more comfortable movement and improved physical function. Relaxing tight muscles supports daily activities and enhances overall quality of life. Benefits may include:

  • Helps reduce muscle stiffness, spasms, and painful cramping.
  • Promotes smoother, more comfortable movement during daily activities.
  • Supports participation in physical therapy and rehabilitation exercises.
  • May help improve sleep quality by reducing nighttime muscle spasms and cramps.
  • Helps make activities such as walking, dressing, and sitting more comfortable.
  • Provides flexible symptom relief when muscle relaxation is needed most.
Side effects of Tizan 2 Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • Take Tizan 2 Tablet exactly as directed by your doctor.
  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break it.
  • You can take this medicine with or without food.
  • Always follow your doctor's exact instructions.

How Tizan 2 Tablet Works

Tizan 2 Tablet belongs to a class of drugs known as central alpha-2 adrenergic agonists. It works by acting directly on the central nervous system, specifically within the brain and spinal cord. It targets specific receptors to temporarily reduce the transmission of nerve signals that cause muscles to tighten, spasm, and cramp. By slowing down these overactive nerve signals, the medicine allows stiff muscles to relax. This action helps to lower overall muscle tone and relieve pain and tightness without completely draining the muscle of its strength, making physical movements smoother and less painful.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Tizan 2 Tablet , as it may increase the risk of adverse effects.

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Pregnancy

Caution

Tizan 2 Tablet is a category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. However, please consult a doctor if you are pregnant

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Breast Feeding

Caution

It is unknown whether Tizan 2 Tablet is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. Tizan 2 Tablet is administered to breastfeeding mothers only if the physician determines that the benefits outweigh the risks.

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Driving

Caution

Tizan 2 Tablet may cause drowsiness, dizziness, or visual disturbances in some individuals. Therefore, avoid driving if you feel any of these symptoms after taking Tizan 2 Tablet .

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Liver

Caution

Take Tizan 2 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Tizan 2 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Tizan 2 Tablet is not recommended for children, as its safety and effectiveness have not been established.

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Heart

Unsafe

This medication is not recommended for patients with cardiac disease due to its adverse effects. However, if prescribed, extreme caution should be exercised.

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Geriatrics

Caution

Tizan 2 Tablet should be used in elderly patients only when prescribed by a doctor. If you have any concerns about using Tizan 2 Tablet in older adults, please consult your doctor.

What if I have taken an overdose of Tizan 2 Tablet

If you take too much of this medicine, seek emergency medical attention or contact a poison control centre immediately. Symptoms of an overdose may include severe drowsiness, confusion, slow or shallow breathing, slow heart rate, or a dangerous drop in blood pressure.

Diet & Lifestyle Advise

  • Stay consistently hydrated: Drink plenty of water throughout the day, as dehydration can worsen muscle cramps and spasms.
  • Incorporate gentle stretching: Perform low-impact, regular stretching exercises or physical therapy as recommended by your healthcare provider to help maintain muscle flexibility.
  • Avoid sudden position changes: Because this medicine can cause dizziness, stand up slowly from a sitting or lying position to prevent falls.
  • Maintain a consistent eating routine: Decide whether you will take your medication with meals or on an empty stomach, and stick to that choice to ensure steady absorption.

Have a query?

How Soon It Starts Working

  • The time required for Tizan 2 Tablet to start to work: Tizan 2 Tablet ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Tizan 2 Tablet last: The effect of Tizan 2 Tablet lasts for 3 to 6 hours.

What if you forget to take Tizan 2 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one. Talk to your doctor if you miss multiple doses.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Take the medicine consistently: Take Tizan 2 Tablet exactly as prescribed and take each dose either always with food or always without food, as food can affect how the medicine is absorbed.
  • Avoid alcohol and use caution during activities requiring alertness: Tizan 2 Tablet may cause drowsiness, dizziness, or reduced alertness. Avoid alcohol, driving, operating machinery, or other activities that require full concentration until you know how the medicine affects you.
  • Change positions slowly: Stand up gradually from a sitting or lying position to help reduce the risk of dizziness, lightheadedness, or fainting.
  • Attend regular monitoring appointments: Keep all scheduled follow-up visits. Your doctor may recommend liver function tests before treatment begins and periodically during the first several months of therapy, especially if higher doses are used.
  • Inform your doctor about all medicines you take: Tell your healthcare provider about all prescription medicines, over-the-counter medicines, and herbal supplements you use to help prevent potentially harmful interactions.
  • Use with caution in certain populations: Tizan 2 Tablet is not routinely recommended for children because its safety and effectiveness have not been well established. Older adults and people with kidney impairment may require closer monitoring and dose adjustments.
  • Avoid this medicine in certain conditions: Do not take Tizan 2 Tablet if you are allergic to Tizan 2 Tablet or any of its ingredients, are currently taking fluvoxamine or ciprofloxacin, have severe liver impairment or active liver disease, have a history of severe uncontrolled low blood pressure, or have severe kidney disease unless specifically advised and monitored by your doctor.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Antidepressants (e.g., fluvoxamine): These medicines can increase the amount of Tizan 2 Tablet in your body, raising the risk of side effects such as excessive drowsiness, dizziness, and low blood pressure.
  • Antibiotics (e.g., ciprofloxacin): These medicines can increase the amount of Tizan 2 Tablet in your body, raising the risk of side effects such as excessive drowsiness, dizziness, and low blood pressure.
  • Opioid pain relievers, sleeping pills, and anti-anxiety medicines: Taking these alongside Tizan 2 Tablet may cause severe drowsiness, slow breathing, impaired coordination, and an increased risk of accidents.
  • Blood pressure-lowering medicines: Combining these with Tizan 2 Tablet may cause your blood pressure to drop too low, leading to dizziness, lightheadedness, or fainting.

Drug-Food Interactions

  • Alcohol: Avoid consuming alcohol while taking Tizan 2 Tablet , as it can significantly increase drowsiness, dizziness, and the risk of accidents or injuries.
  • Food: Taking Tizan 2 Tablet with food can affect how much of the medicine is absorbed by your body. To maintain consistent effects, take each dose either consistently with food or consistently without food.

Drug-Disease Interactions

  • Liver disease: Patients with liver problems should use Tizan 2 Tablet cautiously, as the medicine may build up in the body and increase the risk of side effects.
  • Kidney disease: Reduced kidney function may slow the removal of Tizan 2 Tablet from the body, requiring dose adjustments and closer monitoring.
  • Low blood pressure (hypotension): Tizan 2 Tablet can further lower blood pressure and may worsen existing hypotension, increasing the risk of dizziness and fainting.
TizanidineSaquinavir
Critical

Drug-Drug Interactions

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How does the drug interact with Tizan 2 Tablet:
Coadministration of Tizan 2 Tablet with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tizan 2 Tablet with Cisapride is avoided as it can result in an interaction, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience sudden dizziness, shortness of breath, palpitations, or vomiting. Do not discontinue any medications without consulting your doctor.
TizanidineSaquinavir
Critical
How does the drug interact with Tizan 2 Tablet:
Combining Tizan 2 Tablet with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Tizan 2 Tablet with Saquinavir is not recommended, as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tizan 2 Tablet:
Taking Fluvoxamine with Tizan 2 Tablet it can increases the risk of side effects.

How to manage the interaction:
Although Fluvoxamine with Tizan 2 Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience drowsiness, dizziness, low blood pressure, slurred speech, confusion, or severe weakness, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tizan 2 Tablet:
Coadministration of Ciprofloxacin and Tizan 2 Tablet together can increase the risk of side effects.

How to manage the interaction:
Using Ciprofloxacin and Tizan 2 Tablet together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Tizan 2 Tablet:
Coadministration of Tizan 2 Tablet with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Tizan 2 Tablet with Dronedarone is generally avoided as it can result in an interaction, it can be taken when prescribed by a doctor. If you experience sudden dizziness, shortness of breath, palpitations, or chest pain, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tizan 2 Tablet:
Co-administration of Tizan 2 Tablet with Ziprasidone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Tizan 2 Tablet with Ziprasidone is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tizan 2 Tablet:
Co-administration of Tizan 2 Tablet and Eplerenone may significantly increase eplerenone's blood levels and side effects.

How to manage the interaction:
Taking Tizan 2 Tablet and Eplerenone together can lead to an interaction, it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, chest pain, and palpitations, contact your doctor immediately. Do not stop any medications without a doctor's consultation.
How does the drug interact with Tizan 2 Tablet:
Co-administration of Tizan 2 Tablet with Betaxolol can increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction, Betaxolol and Tizan 2 Tablet can be taken if prescribed by a doctor. If you experience headache, dizziness, palpitations, or excessive sweating, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tizan 2 Tablet:
Coadministration of Amisulpride with Tizan 2 Tablet increases the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although taking amisulpride along with Tizan 2 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Tizan 2 Tablet:
Coadministration of Norfloxacin Tizan 2 Tablet may significantly increase the blood levels and effects of Tizan 2 Tablet.

How to manage the interaction:
Although there is a possible interaction, Norfloxacin with Tizan 2 Tablet can be taken if prescribed by the doctor. Consult the prescriber if you experience symptoms such as dizziness, drowsiness, lightheadedness, headache, shortness of breath, palpitations, clumsiness or unsteadiness, or vision problems. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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TIZANIDINE-2MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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TIZANIDINE-2MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine may significantly increase the blood levels and effects of Tizan 2 Tablet in some patients. Taking caffeine with Tizan 2 Tablet can lead to an interaction. If you experience any symptoms like drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm, contact your doctor immediately. Avoid consumption of Caffeine.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[SKELETAL MUSCLE RELAXANTS]

FAQs

Tizan 2 Tablet is used to treat muscle spasticity (muscles become heavy, stiff, and difficult to move) caused by spinal cord injuries or multiple sclerosis (the immune system attacks the protective covering of nerves). It is also used to relieve pain, stiffness, and discomfort associated with acute musculoskeletal conditions.
Tizan 2 Tablet contains Tizanidine (a skeletal muscle relaxant), which works in the spinal cord and brain by calming overactive nerves and blocking the release of chemicals that trigger muscle tightening. Thereby, it allows the muscles to relax and relieves pain, spasms, and stiffness.
You are not recommended to take Tizan 2 Tablet with ciprofloxacin as co-administration of these two medicines may cause adverse effects such as slurred speech, dizziness, weakness, confusion, low blood pressure, and drowsiness. However, please consult a doctor before taking Tizan 2 Tablet with other medicines.
Tizan 2 Tablet may cause low blood pressure, especially in patients taking antihypertensive drugs (high blood pressure-lowering medicines) or other medicines such as fluvoxamine or ciprofloxacin. However, if you experience signs of low blood pressure, such as dizziness, lightheadedness, blurred vision, or fainting, please consult a physician.
Tizan 2 Tablet is not recommended for patients suffering from psychotic disorders, as it may cause hallucinations or worsen the condition. Therefore, inform your doctor if you have any psychotic disorders before taking Tizan 2 Tablet .
You are recommended to avoid taking caffeinated foods with Tizan 2 Tablet as Tizan 2 Tablet interacts with caffeine and causes severely low blood pressure and increases the risk of other adverse effects such as dizziness, irregular heartbeat, light-headedness, drowsiness, or fainting. However, please consult a doctor if you experience any of these symptoms while taking Tizan 2 Tablet .
The side effects of Tizan 2 Tablet include drowsiness, dry mouth, dizziness, flu-like symptoms, vomiting, constipation, nervousness, sore throat, runny nose or weakness. If these side effects persist or worsen, please consult your doctor.
No, sulfa and aspirin are not present in Tizan 2 Tablet .
Tizan 2 Tablet is gluten free. However, before use, check the package insert of the prescribed brand.
Tizan 2 Tablet may cause insomnia or weight loss as a side effect. Few people may feel excessive sleepiness. However, if you experience such side effects, please consult your doctor.
No, Tizan 2 Tablet does not show on a drug test. Only narcotic drugs are detected on a drug test.
No, you should avoid alcohol while taking Tizan 2 Tablet . Alcohol can significantly increase the drowsiness and dizziness caused by this medicine, which can be dangerous. Talk to your doctor if you have concerns.
Yes, drowsiness is one of the most common side effects of Tizan 2 Tablet . It is highly recommended that you avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor if the sleepiness is severe or does not improve.
Taking Tizan 2 Tablet with food changes how your body absorbs the medicine, making it enter your system faster and in higher amounts. Switching back and forth can cause inconsistent relief or increase side effects. Always be consistent with how you take it and talk to your doctor.
No, you should not stop taking Tizan 2 Tablet abruptly, especially if you have been using it regularly. Stopping suddenly can cause withdrawal symptoms like a rapid heart rate and high blood pressure. Talk to your doctor about how to safely and gradually reduce your dose.
This medicine usually starts working within 1 to 2 hours after you take it. Its effects generally peak within a few hours and wear off after about 6 to 8 hours. Talk to your doctor for advice on timing your doses.
If you have liver disease, you must discuss this with your healthcare provider. This medicine is processed by the liver, and impairment can increase the risk of side effects or liver damage. Talk to your doctor to see if this medicine is safe for you.
The safety of Tizan 2 Tablet during pregnancy and breastfeeding has not been fully established. Animal studies have shown potential risks, and caution is advised, particularly during the first trimester of pregnancy. This medicine should only be used when the expected benefits clearly outweigh the potential risks to the baby. If you are pregnant, planning a pregnancy, or breastfeeding, discuss all available treatment options with your healthcare provider before starting or continuing therapy.

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Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - TIZ0005
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