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Pletoz-100 Tablet 10's
Pletoz-100 Tablet 10's

Pletoz-100 Tablet is used to treat intermittent claudication (pain, tingling, and numbness in the legs). It contains Cilostazol, which works by expanding the veins and reducing the stickiness of the platelets. Therefore, enhancing the blood flow to the lower limbs. This medicine may sometimes cause side effects such as headache, dizziness, diarrhoea, abnormal stool, bleeding, loss of appetite, and rashes. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Health Queries

I had surgery for a thrombus in May 2016 and still experience pain and numbness in my left palm. What should I do?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Pain and numbness can persist long after thrombus surgery due to nerve damage or reduced blood flow. This is common but should not be ignored if it affects daily activities. A doctor review and nerve or physiotherapy evaluation can help manage the symptoms.

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Side effects of Pletoz-100 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Your doctor may adjust the dose of your medication, discontinue, or switch to alternative medicines to manage your symptoms.
  • Drink plenty of water and caffeine-free drinks.
  • Eat more fibre by consuming fruits, vegetables, and whole grains.
  • Avoid processed, spicy, or fatty foods.
  • Try not to skip meals, delay eating, or eat too quickly.
  • Regular exercise can help improve digestion and promote better stool movement.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug-Drug Interactions

verifiedApollotooltip
CilostazolThioridazine
Critical
CilostazolZiprasidone
Critical

Drug-Drug Interactions

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CilostazolThioridazine
Critical
How does the drug interact with Pletoz-100 Tablet:
When Pletoz-100 Tablet is taken with Thioridazine, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Thioridazine with Pletoz-100 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolZiprasidone
Critical
How does the drug interact with Pletoz-100 Tablet:
When Pletoz-100 Tablet is taken with Ziprasidone, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Ziprasidone and Pletoz-100 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolPimozide
Critical
How does the drug interact with Pletoz-100 Tablet:
When Pletoz-100 Tablet is taken with Pimozide, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Pimozide with Pletoz-100 Tablet is not generally advised, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolSparfloxacin
Critical
How does the drug interact with Pletoz-100 Tablet:
When Pletoz-100 Tablet is taken with Sparfloxacin, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Sparfloxacin and Pletoz-100 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolCisapride
Critical
How does the drug interact with Pletoz-100 Tablet:
When Pletoz-100 Tablet is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Cisapride and Pletoz-100 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolMesoridazine
Critical
How does the drug interact with Pletoz-100 Tablet:
When Mesoridazine is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Mesoridazine with Pletoz-100 Tablet, is not recommended but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolDalteparin
Severe
How does the drug interact with Pletoz-100 Tablet:
Co-administration of dalteparin with Pletoz-100 Tablet can increase the risk or severity of bleeding.

How to manage the interaction:
Taking dalteparin with Pletoz-100 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as unusual bleeding or bruising, dizziness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
CilostazolIbrutinib
Severe
How does the drug interact with Pletoz-100 Tablet:
Co-administration of Ibrutinib with Pletoz-100 Tablet can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Ibrutinib with Pletoz-100 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as unusual bleeding or bruising, dizziness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
CilostazolLansoprazole
Severe
How does the drug interact with Pletoz-100 Tablet:
Co-administration of Lansoprazole with Pletoz-100 Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Lansoprazole with Pletoz-100 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
CilostazolDeferasirox
Severe
How does the drug interact with Pletoz-100 Tablet:
Co-administration of deferasirox with Pletoz-100 Tablet can increase the risk or severity of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Taking deferasirox with Pletoz-100 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as stomach pain, bloating, dizziness, lightheadedness, decreased hunger, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Dec 24, 2025 | 7:49 AM IST

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