DALTEPARIN belongs to a class of drugs known as anticoagulants (blood thinner), primarily used to prevent and treat stroke risk, and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. A blood clot can occur in any part of the body, leading to a heart attack, stroke and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs and limbs.
DALTEPARIN contains ‘Dalteparin’ works by inhibiting the production of clotting factors Xa and thrombin. This prevents fibrinogen's conversion (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of DALTEPARIN helps prevent blood clots if you have an increased risk of having a heart attack or stroke.
Take DALTEPARIN as prescribed by your doctor. You are advised to take DALTEPARIN for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience unusual bleeding, haematoma (blood clotting under the skin), thrombocytopenia (low number of platelets), pain and irritation at the injection site. Most of these side effects of DALTEPARIN do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to DALTEPARIN or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using DALTEPARIN. DALTEPARIN should be used with caution in the elderly above 65 years of age as they may be at high risk of bleeding. DALTEPARIN should be given to children only if prescribed by a doctor. Extra care must be taken while brushing your teeth or shaving to prevent bleeding. If you have a stomach ulcer, kidney or liver problems, high blood pressure or bleeding problems, inform your doctor before taking DALTEPARIN. Try not to stop taking this medicine of your own. Stopping a sudden intake of DALTEPARIN may worsen your condition and increase your risk of cardiovascular death, heart attack and stroke.
Blood Clot
DALTEPARIN belongs to a class of drugs known as anticoagulants or blood thinners. DALTEPARIN contains ‘Dalteparin’ used to prevent clot formation in deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain) and heart in patients with atrial fibrillation (irregular heart rhythm). DALTEPARIN is primarily used to prevent and treat the risk of the acute coronary syndrome (sudden reduction or blockage of blood flow to the heart) and stroke by reducing blood clot formation. Besides this, it reduces the risk of clots in people who have undergone knee or hip replacement surgeries and abdominal surgery. DALTEPARIN works by stopping the action of clotting factor Xa and thrombin (a protein that causes clotting). This prevents fibrinogen's conversion (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation.
If you are known to be allergic to DALTEPARIN or any other medicines, please tell your doctor.
If you are pregnant or breastfeeding, it is advised to consult a doctor before using DALTEPARIN.
DALTEPARIN should be given to children only if prescribed by a doctor.
Do not use multiple-dose formulations of DALTEPARIN in neonates and infants as they contain benzyl alcohol that may harm a newborn.
DALTEPARIN should be used with caution in the elderly above 65 years of age as they may be at high risk of bleeding.
If you have diabetes, high blood pressure, congestive heart failure, blood cell disorder (low platelets or low red blood cells), bleeding in the stomach or intestines, had a stroke, kidney, liver or bleeding problems, stomach ulcer, inform your doctor before taking DALTEPARIN.
Do not stop taking DALTEPARIN of your own. Stopping a sudden intake of DALTEPARIN may worsen your condition and increase your risk of cardiovascular death, heart attack and stroke. Hence, you should consult a doctor before stopping the dose of DALTEPARIN.
You should inform the doctor that you are taking DALTEPARIN before any surgery is scheduled.
DALTEPARIN can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural).
Avoid consumption of alcohol while taking DALTEPARIN as it may increase the risk of stomach bleeding.
Extra care must be taken while brushing your teeth or shaving to prevent bleeding.
Drug-Drug Interactions: DALTEPARIN may have interaction with other blood thinners (abciximab, apixaban, enoxaparin, warfarin, clopidogrel, prasugrel, rivaroxaban, dabigatran, anisindione), pain killers (ibuprofen, naproxen, diclofenac, bromfenac, celecoxib), and antihypertensive (lisinopril, losartan, aliskiren, spironolactone, eplerenone).
Drug-Food Interactions: DALTEPARIN may interact with cranberry juice, grapefruit juice, noni juice, pomegranate juice, and green tea. Also, DALTEPARIN may interact with St. John’s wort (herbal medicine for depression), garlic, ginkgo biloba, ginseng, echinacea, goldenseal and coenzyme Q10. Also, avoid alcohol intake as it may increase the risk of bleeding.
Drug-Disease Interactions: If you have haemophilia (blood doesn't clot normally), diabetes, high blood pressure, congestive heart failure, blood cell disorder (low platelets or low red blood cells), bleeding in the stomach or intestines, had a stroke, kidney, liver or bleeding problems, stomach ulcer, inform your doctor before taking DALTEPARIN.
Avoid alcohol consumption while on treatment with DALTEPARIN as it may increase the risk of bleeding.
DALTEPARIN is a Category C pregnancy drug and is given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.
DALTEPARIN is not recommended for use in breastfeeding. If you are breastfeeding, inform your doctor before receiving DALTEPARIN.
DALTEPARIN usually does not affect your ability to drive or operate machinery.
Inform your doctor if you have any pre-existing or a history of liver disease. Your doctor will weigh the benefits and potential risks before prescribing DALTEPARIN. However, it is not recommended for patients with severe liver diseases.
Inform your doctor if you have any pre-existing or a history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing DALTEPARIN. However, it is not recommended in patients with severe kidney diseases.
DALTEPARIN should be given to children only if prescribed by a doctor.
You should have a regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR, or international normalized ratio, to analyze your blood clotting time.
Blood clot: A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart or lungs and result in serious conditions.
Deep vein thrombosis (blood clots in legs): Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling.
Pulmonary embolism (blood clots in the lung): Pulmonary embolism is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough and shortness of breath. Stroke is a condition where a blood clot restricts blood flow to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.
Heart attack: A heart attack is when a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.