apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Fragmin 10000IU Injection 1 ml

Prescription drug
Trailing icon
Fragmin 10000IU Injection 1 ml, Pack of 1 INJECTION
coupon
coupon
coupon
Extra 15% Off with Bank Offers
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Fragmin 10000IU Injection 1 ml is used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung) and reduce the risk of getting clots in people who have undergone knee or hip replacement surgeries. Also, it helps to treat and prevent stroke risk, and heart attack in patients with atrial fibrillation (irregular heart rhythm). It contains Dalteparin which prevents the formation of blood clots by thinning the blood.
Read more

Composition :

DALTEPARIN-10000I.U

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fragmin 10000IU Injection 1 ml

Fragmin 10000IU Injection 1 ml belongs to a class of drugs known as anticoagulants (blood thinner), primarily used to prevent and treat stroke risk, and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. A blood clot can occur in any part of the body, leading to a heart attack, stroke and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs and limbs.

Fragmin 10000IU Injection 1 ml contains ‘Dalteparin’ works by inhibiting the production of clotting factors Xa and thrombin. This prevents fibrinogen's conversion (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Fragmin 10000IU Injection 1 ml helps prevent blood clots if you have an increased risk of having a heart attack or stroke.

Take Fragmin 10000IU Injection 1 ml as prescribed by your doctor. You are advised to take Fragmin 10000IU Injection 1 ml for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience unusual bleeding, haematoma (blood clotting under the skin), thrombocytopenia (low number of platelets), pain and irritation at the injection site. Most of these side effects of Fragmin 10000IU Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Fragmin 10000IU Injection 1 ml or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Fragmin 10000IU Injection 1 ml. Fragmin 10000IU Injection 1 ml should be used with caution in the elderly above 65 years of age as they may be at high risk of bleeding. Fragmin 10000IU Injection 1 ml should be given to children only if prescribed by a doctor. Extra care must be taken while brushing your teeth or shaving to prevent bleeding. If you have a stomach ulcer, kidney or liver problems, high blood pressure or bleeding problems, inform your doctor before taking Fragmin 10000IU Injection 1 ml. Try not to stop taking this medicine of your own. Stopping a sudden intake of Fragmin 10000IU Injection 1 ml may worsen your condition and increase your risk of cardiovascular death, heart attack and stroke.

Uses of Fragmin 10000IU Injection 1 ml

Fragmin 10000IU Injection 1 ml is used to prevent blood clots (thrombus). The detailed uses of Fragmin 10000IU Injection 1 ml are as follows:

  • Prevents Deep Vein Thrombosis (DVT) : Fragmin 10000IU Injection 1 ml is used to prevent blood clots in the deep veins of the legs (DVT), particularly in patients undergoing major surgeries such as hip/knee replacement and abdominal surgery, or in those who are bedridden due to acute illness.
  • Prevents Pulmonary Embolism (PE) : Fragmin 10000IU Injection 1 ml helps reduce the risk of blood clots traveling to the lungs, especially in immobile or hospitalised patients.
  • Prevents Stroke: Fragmin 10000IU Injection 1 ml is used to prevent stroke caused by blood clots in the brain, especially in patients with atrial fibrillation (irregular heartbeat).
  • Manages Acute Coronary Syndrome: Fragmin 10000IU Injection 1 ml helps reduce the risk of complications associated with ACS, such as angina and heart attack, by reducing clot-related blockage in the coronary arteries.
  • Prevents Venous Thromboembolism (VTE) in Cancer: Fragmin 10000IU Injection 1 ml is used as long-term treatment to reduce the recurrence of VTE (blood clots in veins) in cancer patients.

Have a query?

Directions for Use

  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Fragmin 10000IU Injection 1 ml will be administered by a healthcare professional.
  • Do not self-administer.

Medicinal Benefits

Fragmin 10000IU Injection 1 ml belongs to a class of drugs known as anticoagulants or blood thinners. Fragmin 10000IU Injection 1 ml contains ‘Dalteparin’ used to prevent clot formation in deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain) and heart in patients with atrial fibrillation (irregular heart rhythm). Fragmin 10000IU Injection 1 ml is primarily used to prevent and treat the risk of the acute coronary syndrome (sudden reduction or blockage of blood flow to the heart) and stroke by reducing blood clot formation. Besides this, it reduces the risk of clots in people who have undergone knee or hip replacement surgeries and abdominal surgery. Fragmin 10000IU Injection 1 ml works by stopping the action of clotting factor Xa and thrombin (a protein that causes clotting). This prevents fibrinogen's conversion (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation.

How Fragmin 10000IU Injection 1 ml Works

Fragmin 10000IU Injection 1 ml contains ‘Dalteparin’ works by inhibiting the production of clotting factors Xa and thrombin. This prevents fibrinogen's conversion (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes blood flow easily through your veins, making it less likely to form a serious blood clot.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Fragmin 10000 Iu/ml Inj 10ml
  • Increase iron intake through iron-rich foods like red meat, spinach, and beans.
  • Boost vitamin C intake through foods like citrus fruits, bell peppers, and broccoli.
  • Consume foods high in antioxidants, such as berries, leafy greens, and nuts, to help protect against oxidative stress.
  • Stay hydrated by drinking plenty of water.
  • Rest and recover from surgery and transfusion.
  • Avoid strenuous activities like heavy lifting, bending, or exercise.
  • Practice stress-reducing techniques, including meditation, yoga, and deep breathing exercises to help cope with stress and promote relaxation.
  • Follow medical advice and attend follow-up appointments.
  • Focus on consuming a variety of nutrient-dense foods, including plenty of colorful fruits and vegetables, along with whole grains for optimal nutrition.
  • Avoid excessive sugar, salt, and unhealthy fats.
  • Consider increasing foods high in antioxidants, such as berries and leafy greens.
  • Abstain from alcohol or significantly reduce consumption.
  • Achieve and maintain a healthy weight by balancing a nutritious diet with regular physical activity.
  • Engage in moderate exercise, such as brisk walking, most days of the week.
  • Find calm and reduce stress by practicing relaxation methods like mindfulness, meditation, or slow, deliberate breathing.
  • Review medications and supplements with your doctor to ensure they are not contributing to elevated liver enzymes.
  • Reduce saturated fat and sugar intake by limiting processed foods, sugary drinks, and fried foods.
  • Increase fiber intake through plenty of fruits, vegetables, and whole grains.
  • Focus on liver-friendly foods like garlic, turmeric, leafy greens, cruciferous vegetables, and berries.
  • Consider a low-sodium diet by monitoring salt intake.
  • Limit alcohol consumption as even moderate intake can elevate liver enzymes.
  • Engage in regular exercise with moderate-intensity activity most days of the week.
  • Manage weight, as losing a small amount can improve liver health.
  • Quit smoking to prevent worsening liver damage.
  • Practice stress management through relaxation techniques like yoga or meditation.
  • Consult a doctor if your AST and ALT levels are significantly elevated or if you experience symptoms such as fatigue, abdominal pain, jaundice, or loss of appetite.
  • Apply pressure for 5-10 minutes to reduce bleeding.
  • Apply cold compresses or ice packs for 15-20 minutes, repeat every few hours.
  • Consult the doctor and use antihistamines if advised to minimise injection site reaction.
  • Use pain relief medication, like acetaminophen if recommended by the doctor, but avoid NSAIDs if bleeding is a concern.
  • Rotate injection sites and use proper needle size and technique if you are self-administering the medication.
  • Monitor signs such as increased pain, redness, warmth, or pus, and seek medical attention if symptoms worsen.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

What if I have taken an overdose of Fragmin 10000IU Injection 1 ml

The overdose of Fragmin 10000IU Injection 1 ml is unlikely as it is administered by a doctor. However, Fragmin 10000IU Injection 1 ml overdose may lead to hemorrhagic (bleeding) complications.Therefore, if you suspect any adverse reactions or unusual symptoms while on treatment with Fragmin 10000IU Injection 1 ml, please inform your doctor immediately.

Drug Warnings

  • If you are known to be allergic to Fragmin 10000IU Injection 1 ml or any other medicines, please tell your doctor.

  • If you are pregnant or breastfeeding, it is advised to consult a doctor before using Fragmin 10000IU Injection 1 ml.

  • Fragmin 10000IU Injection 1 ml should be given to children only if prescribed by a doctor.

  • Do not use multiple-dose formulations of Fragmin 10000IU Injection 1 ml in neonates and infants as they contain benzyl alcohol that may harm a newborn.

  • Fragmin 10000IU Injection 1 ml should be used with caution in the elderly above 65 years of age as they may be at high risk of bleeding. 

  • If you have diabetes, high blood pressure, congestive heart failure,  blood cell disorder (low platelets or low red blood cells), bleeding in the stomach or intestines, had a stroke, kidney, liver or bleeding problems, stomach ulcer, inform your doctor before taking Fragmin 10000IU Injection 1 ml.

  • Do not stop taking Fragmin 10000IU Injection 1 ml of your own. Stopping a sudden intake of Fragmin 10000IU Injection 1 ml may worsen your condition and increase your risk of cardiovascular death, heart attack and stroke. Hence, you should consult a doctor before stopping the dose of Fragmin 10000IU Injection 1 ml.

  • You should inform the doctor that you are taking Fragmin 10000IU Injection 1 ml before any surgery is scheduled. 

  • Fragmin 10000IU Injection 1 ml can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural).

  • Avoid consumption of alcohol while taking Fragmin 10000IU Injection 1 ml as it may increase the risk of stomach bleeding.

  • Extra care must be taken while brushing your teeth or shaving to prevent bleeding.

Drug-Drug Interactions

verifiedApollotooltip
DalteparinMifepristone
Critical
DalteparinDefibrotide
Critical

Drug-Drug Interactions

Login/Sign Up

DalteparinMifepristone
Critical
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Combining Mifepristone with Fragmin 10000 Iu/ml Inj 10ml can increase the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Fragmin 10000 Iu/ml Inj 10ml with Mifepristone may possibly lead to an interaction, they can be taken if a doctor prescribes it. Emergency medical attention may be needed for persistent, excessive bleeding. Without consulting a doctor. Do not stop using any medications without talking to a doctor.
DalteparinDefibrotide
Critical
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Combining Defibrotide with Fragmin 10000 Iu/ml Inj 10ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Fragmin 10000 Iu/ml Inj 10ml with Defibrotide may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
DalteparinDipyridamole
Critical
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Combining Dipyridamole with Fragmin 10000 Iu/ml Inj 10ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Fragmin 10000 Iu/ml Inj 10ml with Dipyridamole may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
DalteparinFenoprofen
Severe
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Combining Fenoprofen with Fragmin 10000 Iu/ml Inj 10ml can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Fragmin 10000 Iu/ml Inj 10ml with Fenoprofen may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
DalteparinTenecteplase
Severe
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Combining Tenecteplase with Fragmin 10000 Iu/ml Inj 10ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Fragmin 10000 Iu/ml Inj 10ml with Tenecteplase may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
DalteparinIbrutinib
Severe
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Co-administration of Ibrutinib with Fragmin 10000 Iu/ml Inj 10ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ibrutinib with Fragmin 10000 Iu/ml Inj 10ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
DalteparinRuxolitinib
Severe
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Using Fragmin 10000 Iu/ml Inj 10ml together with ruxolitinib may increase the risk of bleeding.

How to manage the interaction:
Although taking Fragmin 10000 Iu/ml Inj 10ml and Ruxolitinib together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness call a doctor right away. Do not discontinue any medications without consulting a doctor.
DalteparinEtodolac
Severe
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Taking Etodolac with Fragmin 10000 Iu/ml Inj 10ml can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although there is a possible interaction between Etodolac and Fragmin 10000 Iu/ml Inj 10ml, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
DalteparinDasatinib
Severe
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Coadministration of Dasatinib with Fragmin 10000 Iu/ml Inj 10ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Fragmin 10000 Iu/ml Inj 10ml and Dasatinib together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms - bruising, dizziness, severe headache, or weakness - make sure to contact a doctor. Do not discontinue any medications without consulting a doctor.
DalteparinSulindac
Severe
How does the drug interact with Fragmin 10000 Iu/ml Inj 10ml:
Combining Sulindac with Fragmin 10000 Iu/ml Inj 10ml can increase the risk of bleeding tendencies.

How to manage the interaction:
Although taking Fragmin 10000 Iu/ml Inj 10ml with Sulindac may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Do not make any changes in your diet without first talking to your doctor.
  • Avoid vitamin K-rich foods such as coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, and Brussels sprouts as they may decrease the effectiveness of Fragmin 10000IU Injection 1 ml.
  • Avoid cranberry juice, grapefruit juice, noni juice, pomegranate juice and green tea as they may interact with Fragmin 10000IU Injection 1 ml and lead to unwanted side effects.
  • Do the regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid the consumption of alcohol as it may increase the risk of bleeding.
  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Fragmin 10000IU Injection 1 ml.
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals and maintain a healthy diet that includes fresh fruits and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

All Substitutes & Brand Comparisons

bannner image

Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Fragmin 10000IU Injection 1 ml as it may increase the risk of bleeding.

bannner image

Pregnancy

Caution

Fragmin 10000IU Injection 1 ml is a Category C pregnancy drug and is given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

bannner image

Breast Feeding

Caution

Fragmin 10000IU Injection 1 ml is not recommended for use in breastfeeding. If you are breastfeeding, inform your doctor before receiving Fragmin 10000IU Injection 1 ml.

bannner image

Driving

Caution

Fragmin 10000IU Injection 1 ml usually does not affect your ability to drive or operate machinery.

bannner image

Liver

Caution

Inform your doctor if you have any pre-existing or a history of liver disease. Your doctor will weigh the benefits and potential risks before prescribing Fragmin 10000IU Injection 1 ml. However, it is not recommended for patients with severe liver diseases.

bannner image

Kidney

Caution

Inform your doctor if you have any pre-existing or a history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Fragmin 10000IU Injection 1 ml. However, it is not recommended in patients with severe kidney diseases.

bannner image

Children

Caution

Fragmin 10000IU Injection 1 ml should be given to children only if prescribed by a doctor.

FAQs

Fragmin 10000IU Injection 1 ml is used to prevent the risk of stroke, and heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.

Fragmin 10000IU Injection 1 ml contains Dalteparin, an anticoagulant (blood thinner) that inhibits the production of clotting factors Xa (a protein that causes clotting). It prevents the conversion of fibrinogen to fibrin (a protein that binds platelets together and forms a clot) and helps prevent blood clot formation.

No, you are not recommended to take clopidogrel with Fragmin 10000IU Injection 1 ml as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

It is recommended to avoid taking grapefruit and grapefruit juice while taking Fragmin 10000IU Injection 1 ml. It contains compounds that slow down the metabolism of Fragmin 10000IU Injection 1 ml and increase the activity leading to bleeding.

Do not stop taking Fragmin 10000IU Injection 1 ml without consulting your doctor to worsen the condition. Therefore, take Fragmin 10000IU Injection 1 ml for as long as your doctor has prescribed it.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ?G? Block , Bandra Kurla Complex, Bandra East , Mumbai ? 400051.
Other Info - FRA0060

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Sep 10, 2025 | 3:15 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/drug-interactions/dalteparin-index.html
  2. https://www.medicines.org.uk/emc/files/pil.4247.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/020287s050lbl.pdf

Buy best Cardiology products by

whatsapp Floating Button
Buy Now
Add to Cart