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  3. Posanex Oral Suspension 105 ml

Posanex Oral Suspension 105 ml, Pack of 1 SUSPENSION
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Posanex Oral Suspension is used to prevent and treat fungal infections. It contains posaconazole which works by inhibiting fungal cell growth and causing cell death. In some cases, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, and cough. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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:संरचना :

पोसाकोनाज़ोल-40एमजी

निर्माता/विपणक :

भारत सीरम और टीके लिमिटेड

सेवन प्रकार :

मौखिक

वापसी नीति :

वापसी योग्य नहीं

इसके बाद या बाद में समाप्त होता है :

Jan-27

Posanex Oral Suspension 105 ml के बारे में

Posanex Oral Suspension 105 ml एज़ोल एंटीफंगल नामक दवाओं के एक वर्ग में है। इसका उपयोग फंगल संक्रमण को रोकने और उनका इलाज करने के लिए किया जाता है जब अन्य एंटीफंगल दवाओं ने काम नहीं किया है, या आपको उन्हें लेना बंद करना पड़ा है। यह गंभीर रूप से इम्यूनो कॉम्प्रोमाइज्ड होने के कारण इन संक्रमणों को विकसित करने के उच्च जोखिम वाले रोगियों में आक्रामक एस्परगिलस और कैंडिडा संक्रमणों को रोकने के लिए भी संकेत दिया गया है, जैसे कि ग्राफ्ट-बनाम-होस्ट रोग (जीवीएचडी) के साथ हेमटोपोइएटिक स्टेम सेल प्रत्यारोपण (एचएससीटी) प्राप्तकर्ता या कीमोथेरेपी से लंबे समय तक न्यूट्रोपेनिया के साथ हेमटोलोगिक विकृतियों वाले।

Posanex Oral Suspension 105 ml में पॉसकोनाज़ोल नामक एक दवा होती है। यह एक ट्राईजोल एंटीफंगल एजेंट है और कुछ एंजाइमों (पी-450 आश्रित एंजाइम, स्टेरोल 14α-डीमेथीलेज़) को अवरुद्ध करके अपनी एंटीफंगल गतिविधि को बढ़ाता है। यह एर्गोस्टेरॉल के संश्लेषण को रोकता है, जो फंगल कोशिका झिल्ली का एक प्रमुख घटक है, और मिथाइलेटेड स्टेरोल अग्रदूतों का संचय है। इसके परिणामस्वरूप फंगल कोशिका वृद्धि और कोशिका मृत्यु का निषेध होता है। इस प्रकार, यह संक्रमण का इलाज करता है।

Posanex Oral Suspension 105 ml को अपने डॉक्टर द्वारा बताए अनुसार लें। आपको सलाह दी जाती है कि Posanex Oral Suspension 105 ml को तब तक लें जब तक आपके डॉक्टर ने आपकी चिकित्सा स्थिति के आधार पर इसे निर्धारित किया है। कुछ मामलों में, आपको दस्त, मतली, बुखार, उल्टी, सिरदर्द, खांसी और रक्त में पोटेशियम का स्तर कम हो सकता है। Posanex Oral Suspension 105 ml के इन दुष्प्रभावों में से अधिकांश को चिकित्सा की आवश्यकता नहीं होती है और धीरे-धीरे समय के साथ हल हो जाती है। हालांकि, अगर साइड इफेक्ट बने रहते हैं या बिगड़ते हैं, तो कृपया अपने डॉक्टर से सलाह लें।

अपने डॉक्टर को सूचित करें कि क्या आपको Posanex Oral Suspension 105 ml में मौजूद किसी भी घटक से एलर्जी है या अतिसंवेदनशीलता है या यदि आप गर्भवती हैं, तो आपको संदेह है कि आप गर्भवती हैं, बच्चा पैदा करने की योजना बना रही हैं या स्तनपान करा रही हैं; आपका डॉक्टर Posanex Oral Suspension 105 ml तभी लिखेगा जब लाभ जोखिम से अधिक हों। Posanex Oral Suspension 105 ml लेने से पहले, किसी भी संभावित प्रतिकूल प्रभाव या अंतःक्रियाओं से बचने के लिए अपने डॉक्टर को अपने मेडिकल इतिहास और चल रहे उपचारों के बारे में सूचित करें।

Posanex Oral Suspension 105 ml के उपयोग

फंगल संक्रमण के इलाज और गंभीर रूप से इम्यूनो कॉम्प्रोमाइज्ड रोगियों में आक्रामक एस्परगिलस और कैंडिडा संक्रमण के प्रोफिलैक्सिस में Posanex Oral Suspension 105 ml का उपयोग किया जाता है।

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उपयोग के लिए निर्देश

प्रत्येक उपयोग से पहले बोतल को अच्छी तरह से हिलाएं। मापने वाले कप/खुराक सिरिंज/ड्रॉपर का उपयोग करके निर्धारित खुराक मुंह से लें।

औषधीय लाभ

पोसाकोनाज़ोल एक एंटीफंगल दवा है जो Posanex Oral Suspension 105 ml में मौजूद है। यह वयस्कों में फंगल संक्रमण के इलाज में प्रभावी है। यह उन रोगियों में आक्रामक एस्परगिलस और कैंडिडा संक्रमणों को रोकने के लिए भी संकेत दिया गया है, जो गंभीर रूप से इम्यूनो कॉम्प्रोमाइज्ड हैं और इन संक्रमणों को विकसित करने के उच्च जोखिम में हैं, जैसे कि ग्राफ्ट-बनाम-होस्ट रोग (जीवीएचडी) के साथ हेमटोपोइएटिक स्टेम सेल प्रत्यारोपण (एचएससीटी) प्राप्तकर्ता या कीमोथेरेपी से लंबे समय तक न्यूट्रोपेनिया के साथ हेमटोलोगिक विकृतियों वाले।

भंडारण

धूप से दूर ठंडी और सूखी जगह पर रखें
Side effects of Posanex Oral Suspension 105 ml
  • Avoid alcohol as it may be harmful and worsen certain condition.
  • Take nutritional supplements only as advised by your doctor.
  • Limit sodium intake.
  • Consult your doctor for medications to treat your condition effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

दवा संबंधी चेतावनी

अपने डॉक्टर को सूचित करें कि क्या आपको Posanex Oral Suspension 105 ml में मौजूद किसी भी घटक से एलर्जी है या अतिसंवेदनशीलता है या यदि आप गर्भवती हैं, तो आपको संदेह है कि आप गर्भवती हैं, बच्चा पैदा करने की योजना बना रही हैं या स्तनपान करा रही हैं; आपका डॉक्टर Posanex Oral Suspension 105 ml तभी लिखेगा जब लाभ जोखिम से अधिक हों। Posanex Oral Suspension 105 ml लेने से पहले, किसी भी संभावित प्रतिकूल प्रभाव या अंतःक्रियाओं से बचने के लिए अपने डॉक्टर को अपने मेडिकल इतिहास और चल रहे उपचारों के बारे में सूचित करें। और साथ ही, अपने डॉक्टर को Posanex Oral Suspension 105 ml निर्धारित करने से पहले बताएं कि क्या आपको अतालता और क्यूटीसी लम्बाई, लीवर की समस्याएं, या आपके रक्त में पोटेशियम, मैग्नीशियम या कैल्शियम का स्तर कम है।

Drug-Drug Interactions

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PosaconazoleSirolimus
Critical
PosaconazoleRanolazine
Critical

Drug-Drug Interactions

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PosaconazoleSirolimus
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Coadministration of sirolimus with Posanex Oral Suspension 105 ml can lower the levels of sirolimus in the blood.

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml with sirolimus, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleRanolazine
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
When Posanex Oral Suspension 105 ml is taken with Ranolazine, may significantly increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml and ranolazine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
PosaconazoleIsavuconazole
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
When Isavuconazole is taken with Posanex Oral Suspension 105 ml, it can increase the levels of isavuconazole in the blood.

How to manage the interaction:
Although there is an interaction between isavuconazole and Posanex Oral Suspension 105 ml, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleEliglustat
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Taking eliglustat with Posanex Oral Suspension 105 ml can increase the levels of eliglustat in the blood.

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml and eliglustat, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, a slow heart rate, or a weak pulse. Do not discontinue any medications without consulting a doctor.
PosaconazoleLovastatin
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Taking lovastatin with Posanex Oral Suspension 105 ml can increase the levels of lovastatin in the blood which can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Lovastatin and Posanex Oral Suspension 105 ml, they can be taken together if advised by a doctor. However, contact a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.
PosaconazoleAtorvastatin
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Taking atorvastatin with Posanex Oral Suspension 105 ml can increase the blood levels of atorvastatin. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml with atorvastatin, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
PosaconazoleZiprasidone
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Coadministration of Posanex Oral Suspension 105 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Posanex Oral Suspension 105 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
PosaconazoleSimvastatin
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Taking Posanex Oral Suspension 105 ml with Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Posanex Oral Suspension 105 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleEplerenone
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Coadministration of Posanex Oral Suspension 105 ml with eplerenone can increase the blood levels of eplerenone. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml and eplerenone, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleDronedarone
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
When Dronedarone is taken with Posanex Oral Suspension 105 ml, can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Posanex Oral Suspension 105 ml with Dronedarone is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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आहार और जीवनशैली सलाह```

  • Take the medication as directed by the doctor and at regular intervals if you take Posanex Oral Suspension 105 ml for more than one day.
  • Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Posanex Oral Suspension 105 ml.
  • Continue taking your normal regular diet unless your doctor prescribes a specific diet.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, alcohol and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during Posanex Oral Suspension 105 ml treatment to enhance a healthy lifestyle practice.

आदत बनाने वाला

नहीं

Posanex Oral Suspension Substitute

Substitutes safety advice
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शराब

अपने डॉक्टर से सलाह लें

शराब के साथ Posanex Oral Suspension 105 ml की परस्पर क्रिया अज्ञात है। यदि आपको इसे लेकर कोई चिंता है, तो कृपया अपने डॉक्टर से चर्चा करें।

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गर्भावस्था

अपने डॉक्टर से सलाह लें

जब तक स्पष्ट रूप से आवश्यक न हो, गर्भावस्था के दौरान Posanex Oral Suspension 105 ml का उपयोग नहीं किया जाना चाहिए। इसलिए, अपने डॉक्टर को सूचित करें यदि आप गर्भवती हैं या गर्भावस्था का संदेह है। Posanex Oral Suspension 105 ml को निर्धारित करने से पहले आपका डॉक्टर लाभों और संभावित जोखिमों का वजन करेगा।

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स्तनपान

अपने डॉक्टर से सलाह लें

स्तनपान/नर्सिंग माताओं में Posanex Oral Suspension 105 ml के उपयोग पर अभी तक कोई पर्याप्त शोध नहीं हुआ है। अपने डॉक्टर को सूचित करें यदि आप Posanex Oral Suspension 105 ml लेने से पहले एक नर्सिंग माँ हैं; आपका डॉक्टर तय करेगा कि क्या स्तनपान कराने वाली माताओं द्वारा Posanex Oral Suspension 105 ml लिया जा सकता है।

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ड्राइविंग

सावधानी

यह अज्ञात है कि क्या Posanex Oral Suspension 105 ml ड्राइव करने की क्षमता को बदल देता है, इसलिए ड्राइव न करें या मशीनरी न चलाएं यदि आपको ध्यान केंद्रित करने और प्रतिक्रिया करने की आपकी क्षमता को प्रभावित करने वाले कोई लक्षण दिखाई देते हैं।

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जिगर

अपने डॉक्टर से सलाह लें

यदि आपके पास लीवर की दुर्बलता/विकार का इतिहास है तो Posanex Oral Suspension 105 ml लेने से पहले अपने डॉक्टर को सूचित करें। आपका डॉक्टर केवल तभी लिखेगा जब लाभ जोखिमों से अधिक हों।

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गुर्दा

अपने डॉक्टर से सलाह लें

यदि आपके पास किडनी की दुर्बलता/विकार का इतिहास है तो Posanex Oral Suspension 105 ml लेने से पहले अपने डॉक्टर को सूचित करें। आपका डॉक्टर केवल तभी लिखेगा जब लाभ जोखिमों से अधिक हों।

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बच्चे

अपने डॉक्टर से सलाह लें

बच्चों के लिए Posanex Oral Suspension 105 ml का उपयोग करने से पहले कृपया डॉक्टर से सलाह लें।

FAQs

Posanex Oral Suspension 105 ml is used to treat fungal infections and prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.

Posanex Oral Suspension 105 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.

Posanex Oral Suspension 105 ml is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Posanex Oral Suspension 105 ml.

If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.

Like all medicines, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood, although not everybody gets them. Most of these side effects of Posanex Oral Suspension 105 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Take Posanex Oral Suspension 105 ml as prescribed by your doctor. You are advised to take Posanex Oral Suspension 105 ml for as long as your doctor has prescribed it for you based on your medical condition.

उत्पत्ति देश

India

निर्माता/मार्केटर पता

17Th Floor, Hoechst House, Nariman Point, Mumbai 400 021, Maharashtra, India.
Other Info - POS0081

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:21 AM IST

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