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Posid 50 mg Capsule is used to treat various types of cancer, including testicular cancer, small cell lung cancer, blood cancer, ovarian cancer, and lymphoma. It contains Etoposide which works by preventing the growth and spread of cancer cells. In some cases, this medicine may cause side effects such as temporary hair loss, nausea and vomiting, loss of appetite, diarrhoea, and irregular heartbeat. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Posid 50 mg Capsule
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.

Drug-Drug Interactions

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EtoposideRotavirus vaccine
Critical

Drug-Drug Interactions

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EtoposideRotavirus vaccine
Critical
How does the drug interact with Posid 50 mg Capsule:
When the Rotavirus vaccine is used together with Posid 50 mg Capsule, it may not work as well.

How to manage the interaction:
Taking Posid 50 mg Capsule with the Rotavirus vaccine can cause an, please consult doctor before taking it. You may be at risk of acquiring an infection from the vaccination or having a decreased response of the vaccine depending on the dose and length of time you have been on Posid 50 mg Capsule. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Posid 50 mg Capsule:
When Infliximab is taken with Posid 50 mg Capsule, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Posid 50 mg Capsule with Infliximab can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
EtoposideGolimumab
Severe
How does the drug interact with Posid 50 mg Capsule:
When Posid 50 mg Capsule is used with Golimumab, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Posid 50 mg Capsule and Golimumab, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Posid 50 mg Capsule:
When Posid 50 mg Capsule is used with Fingolimod, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Posid 50 mg Capsule with Fingolimod together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideIdelalisib
Severe
How does the drug interact with Posid 50 mg Capsule:
When Posid 50 mg Capsule is used with Idelalisib, Idelalisib may increase the blood levels and effects of Posid 50 mg Capsule.

How to manage the interaction:
Taking Posid 50 mg Capsule with Idelalisib together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EtoposideIvacaftor
Severe
How does the drug interact with Posid 50 mg Capsule:
When Fenofibrate is used in combination with Ivacaftor, the blood levels of Fenofibrate might be raised.

How to manage the interaction:
Taking Posid 50 mg Capsule with Ivacaftor together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Posid 50 mg Capsule:
Taking Posid 50 mg Capsule with natalizumab, especially taking both simultaneously with little to no time in between, may raise the risk of serious infections.

How to manage the interaction:
Although taking Posid 50 mg Capsule and Natalizumab together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. progressive weakening on one side of your body, clumsiness of limbs, visual disturbance, disorientation, or changes in your thinking, memory, or personality. Do not stop using any medications without talking to a doctor.
How does the drug interact with Posid 50 mg Capsule:
When Posid 50 mg Capsule is used with Adalimumab, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Posid 50 mg Capsule and Adalimumab together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Posid 50 mg Capsule:
Co-administration of Posid 50 mg Capsule with deferiprone can cause a decrease in white blood cell count, and taking it with Posid 50 mg Capsule, which can similarly alter white blood cell count or bone marrow function, may enhance the risk. As a result, you may be more susceptible to serious infections.

How to manage the interaction:
There may be a possibility of interaction between Posid 50 mg Capsule and Deferiprone, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideVoclosporin
Severe
How does the drug interact with Posid 50 mg Capsule:
When Posid 50 mg Capsule is used with Voclosporin, the risk of severe infections, as well as certain cancers including skin cancer and cancer of the lymph glands (lymphoma), increases.

How to manage the interaction:
Although taking Posid 50 mg Capsule and Voclosporin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, If you experience a fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ETOPOSIDE-50MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ETOPOSIDE-50MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit

How to manage the interaction:
Consumption of Grapefruit, grapefruit juice with Posid 50 mg Capsule, blocks metabolism, which might raise Posid 50 mg Capsule levels in the blood. Avoid the consumption of grapefruit juice while taking Posid 50 mg Capsule.

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