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Pregout Kit 1's

Pregout Kit is used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. It also works in the second trimester of pregnancy. It contains Mifepristone and Misoprostol, which blocks the effects of the progesterone hormone required in women to continue the pregnancy. Also, it increases the womb's (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. In some cases, you may experience side effects such as nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Pregout Kit
  • Your doctor may reduce your medication dose gradually if you have too much cortisol, while still managing your condition.
  • Try hot baths, massages, and gentle exercises like water aerobics or tai chi to ease aches and pains.
  • Limit sodium and fatty foods to reduce health risks.
  • Consume foods rich in calcium, like dairy, leafy greens, fortified plant milk, and salmon, to support bone health.
  • Include sources of vitamin D in your meals, such as cod liver oil, egg yolks, fortified milk, and fatty fish like swordfish and salmon.
  • Make time for things you enjoy and set limits to avoid getting too tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

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Thanks — I’ve noted your acknowledgment about Pregout Kit 1's and its product details.

⚕️ What this is

  • Pregout Kit 1's contains mifepristone and misoprostol, used for medical termination of pregnancy and intended to be given under medical supervision.
  • It is an oral tablet pack (SKU PRE1192), prescription-only, priced at ₹408.4, and listed as expiring Jan-27.

💊 Key actions (what to do next)

  • See a gynecologist for counseling, confirmation of suitability, and supervised administration.
  • Follow the clinic’s schedule for medication and the planned follow-up visit(s) including ultrasound to confirm completion.
  • Avoid strenuous activity and follow post-treatment instructions the doctor gives.
  • Keep the prescription and packaging and do not attempt unsupervised self-administration.
  • Use emergency care (see below) for significant problems.

⚠️ Warning signs — seek urgent care

  • Heavy bleeding (soaking more than 2 sanitary pads per hour for several hours).
  • Fever above 38°C (100.4°F) lasting over 24 hours or worsening abdominal pain.
  • Foul-smelling vaginal discharge or signs of infection.

🩺 FOLLOW_UP

  • Would you like brief guidance on common side effects, what to expect during the procedure, or nearby clinic referral?

If urgent, call Apollo Emergency - 1066 and contact a gynecologist promptly.

Have a query?

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Pregout Kit interacts with corticosteroids (dexamethasone), antifungal (ketoconazole, itraconazole), antibiotics (erythromycin, rifampicin),  anti-epileptic (phenytoin, phenobarbital, carbamazepine), immunosuppressants (cyclosporine, tacrolimus, sirolimus), medicines to treat migraine (ergotamine). So, Pregout Kit should not be taken along with these drugs.

Drug-Food Interactions: Please tell your doctor about all the Vitamins, herbs, and supplements you are taking as Pregout Kit may interact with them to produce unpleasant side effects. Also, Pregout Kit is known to interact with St John’s Wort (a natural remedy used to treat mild depression), and grapefruit juice.

Drug-Disease Interactions: Pregout Kit should be taken with caution in people who have a bleeding problem, confirmed or suspected ectopic pregnancy, heart problem, liver or kidney disease, vaginal bleeding, porphyria (an inherited blood disease that may cause nervous system or skin problems).

Mifepristone + MisoprostolLurasidone
Critical
Mifepristone + MisoprostolTriamcinolone
Critical

Drug-Drug Interactions

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Mifepristone + MisoprostolLurasidone
Critical
How does the drug interact with Pregout Kit:
Co-administration of Lurasidone with Pregout Kit can increase the levels of Lurasidone which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Lurasidone with Pregout Kit together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any abnormal muscle movements, seizures (fits), high blood sugar, dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mifepristone + MisoprostolTriamcinolone
Critical
How does the drug interact with Pregout Kit:
Using Pregout Kit with Triamcinolone can significantly reduce the effects of Triamcinolone.

How to manage the interaction:
Taking Triamcinolone with Pregout Kit is not recommended but can be taken if prescribed by a doctor. However, if you notice any unusual symptoms contact a doctor. Do not discontinue any medications without consulting a doctor.
Mifepristone + MisoprostolTolvaptan
Critical
How does the drug interact with Pregout Kit:
When Tolvaptan is taken with Pregout Kit, it may increase the levels of Tolvaptan, which may increase the risk of side effects.

How to manage the interaction:
Taking Tolvaptan and Pregout Kit together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
Mifepristone + MisoprostolApixaban
Critical
How does the drug interact with Pregout Kit:
Co-administration of Pregout Kit and Apixaban may increase the risk and/or severity of vaginal bleeding.

How to manage the interaction:
Taking Apixaban with Pregout Kit together is not generally recommended as it may lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience persistent, excessive bleeding, consult the doctor. Without consulting a doctor, never stop taking any medication.
Mifepristone + MisoprostolLovastatin
Critical
How does the drug interact with Pregout Kit:
When Pregout Kit is taken with Lovastatin, it can increase the risk of side effects including rhabdomyolysis (a condition that causes your muscles to break down (disintegrate), which leads to muscle death).

How to manage the interaction:
Taking Lovastatin with Pregout Kit is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
Mifepristone + MisoprostolMesoridazine
Critical
How does the drug interact with Pregout Kit:
Co-administration of Mesoridazine with Pregout Kit can increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Pregout Kit is not recommended, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, vomiting, constipation, abdominal cramping, chest pain, or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
Mifepristone + MisoprostolPrednisolone
Critical
How does the drug interact with Pregout Kit:
When Pregout Kit is taken with Prednisolone, the effects of Prednisolone might be considerably reduced, which may be less effective in treating your condition.

How to manage the interaction:
Taking Prednisolone with Pregout Kit is not recommended, they can be taken together if advised by a doctor. Do not discontinue the medication without consulting a doctor.
Mifepristone + MisoprostolFondaparinux
Critical
How does the drug interact with Pregout Kit:
Using Pregout Kit together with Fondaparinux may increase the risk and/or severity of vaginal bleeding in women

How to manage the interaction:
Taking Fondaparinux with Pregout Kit together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mifepristone + MisoprostolFluticasone furoate
Critical
How does the drug interact with Pregout Kit:
Co-administration of Fluticasone furoate with Pregout Kit can reduce the effect of fluticasone furoate.

How to manage the interaction:
Taking Fluticasone furoate with Pregout Kit is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
Mifepristone + MisoprostolTicagrelor
Critical
How does the drug interact with Pregout Kit:
Co-administration of Pregout Kit with Ticagrelor can increase the risk of vaginal bleeding.

How to manage the interaction:
Taking Ticagrelor with Pregout Kit is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any symptoms like heavy period bleeding for more than 7 days, weakness, tiredness, shortness of breath, or paleness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
MIFEPRISTONE-200MG+MISOPROSTOL-200MCGFruit juices, Fruits
Moderate

Drug-Food Interactions

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MIFEPRISTONE-200MG+MISOPROSTOL-200MCGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or grapefruit juice along with Pregout Kit may cause the medication's blood levels to rise to unwanted levels and raise the chance of adverse effects. Avoid taking grapefruit or grapefruit juice along with Pregout Kit as this can raise the chance of adverse effects. However, consult a doctor if you experience headache, dizziness, fatigue, nausea, vomiting, cramping, diarrhea, hypokalemia (low blood potassium), fluid retention, swelling, and high blood pressure.

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