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About Mifrex Plus Tablet Kit 10's
Mifrex Plus Tablet Kit 10's belongs to a group of gynaecological medications called ‘Abortifacient’ used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. Mifrex Plus Tablet Kit 10's also works in the second trimester of pregnancy.
Mifrex Plus Tablet Kit 10's contains two medicines, namely: Mifepristone and Misoprostol. Mifepristone is an anti-hormone (anti-progestogen) that blocks the effects of the progesterone hormone required in women to continue the pregnancy. On the other hand, Misoprostol is a prostaglandin that increases the womb’s (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. Thus, Mifrex Plus Tablet Kit 10's together cause termination of pregnancy and must be used one after the other for medical abortion.
A medical abortion generally involves 2-3 visits to a doctor or clinic, which includes giving medicines and then confirmation of termination of pregnancy. Following are the schedule involved in medical abortion:
Day 1: Medical counselling and examination where doctor instructs to take one tablet of mifepristone (200 mcg)
Day 2 to 3: You must return to the hospital/clinic 36 to 48 hours after taking the first dose of mifepristone. Your doctor will tell you about this. The tablet of Misoprostol (800 mcg) will now be given either orally or vaginally.
Day 7 to 14: The doctor will confirm and make sure whether the medical abortion has been completed or not. If the abortion is not complete, you might require more follow-up visits.
In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Mifrex Plus Tablet Kit 10's subside with time. But if vaginal bleeding does not stop, please visit the doctor immediately, as it requires immediate medical attention.
Mifrex Plus Tablet Kit 10's should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting Mifrex Plus Tablet Kit 10's if you have had an ectopic pregnancy (when the womb grows in the fallopian tube), using an intrauterine device, or you are breastfeeding, any bleeding disorder or heart problem. Do not strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.
Uses of Mifrex Plus Tablet Kit 10's
Mifrex Plus Tablet Kit 10's is used for Medical abortion. The detailed uses of Mifrex Plus Tablet Kit 10's are as follows:

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Directions for Use
Key Benefits
Mifrex Plus Tablet Kit 10's contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone) needed to maintain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Mifrex Plus Tablet Kit 10's to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete. On the other hand, the second medicine is Misoprostol, a prostaglandin analogue that helps increase uterine contractions and relaxes the cervix. Thus Together Mifrex Plus Tablet Kit 10's terminates the state of pregnancy. Misoprostol should be taken at least 24-36 hours after taking mifepristone, either orally or vaginally. This is a non-surgical method which is 90% successful.
How Mifrex Plus Tablet Kit 10's Works
Storage
What if I have taken an overdose of Mifrex Plus Tablet Kit 10's
Drug Warnings
Do not take Mifrex Plus Tablet Kit 10's if you are allergic to misoprostol and mifepristone, have a heart fitted with an artificial valve, have heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Mifrex Plus Tablet Kit 10's in these conditions can cause life-threatening conditions in an individual. Mifrex Plus Tablet Kit 10's is known to cause sleepiness, so driving or operating machinery should not be done. If you use contraceptive devices like the intrauterine device (IUD), please remove it before taking Mifrex Plus Tablet Kit 10's. Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (a natural remedy used to treat mild depression) grapefruit juice should not be taken when taking Mifrex Plus Tablet Kit 10's as it is known to interact.
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Alcohol
Safe if prescribed
Alcohol is known to cause excessive drowsiness and increases uterine bleeding if taken along with Mifrex Plus Tablet Kit 10's.
Pregnancy
Consult your doctor
Mifrex Plus Tablet Kit 10's is used for medical abortion. If taken in pregnancy, it can lead to abortion.
Breast Feeding
Consult your doctor
Mifrex Plus Tablet Kit 10's should not be taken if breastfeeding as it may pass through the milk to the baby.
Driving
Safe if prescribed
Driving is unsafe when taking Mifrex Plus Tablet Kit 10's as it might increase the risk of excessive bleeding.
Liver
Consult your doctor
Mifrex Plus Tablet Kit 10's to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
Consult your doctor
Mifrex Plus Tablet Kit 10's to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
Safe if prescribed
Mifrex Plus Tablet Kit 10's is not recommended for children below the age of 12. The safety and effectiveness of Mifrex Plus Tablet Kit 10's have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Mifrex Plus Tablet Kit 10's or not.
Heart
Mifrex Plus Tablet Kit 10's should be used under caution in cardiac patients as it can lead to QT prolongation.
Geriatrics
Consult your doctor
Limited information is available for use in erderly patients. Please consult your doctor.
Mifrex Plus Tablet Kit 10's is used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. Mifrex Plus Tablet Kit 10's also works in the second trimester of pregnancy.
Mifrex Plus Tablet Kit 10's contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. Misoprostol is a prostaglandin analogue that helps increase uterine contractions and relaxes the cervix. Misoprostol should be taken 24-36 hours after taking mifepristone, either orally or vaginally.
No, Mifrex Plus Tablet Kit 10's should be taken in the dose and duration as advised by the doctor. Taking it in more than the recommended dose might cause unpleasant side effects like excessive uterine or vaginal bleeding.
No, Mifrex Plus Tablet Kit 10's is not known to affect any future chances of pregnancy. Mifrex Plus Tablet Kit 10's is used for medical abortion of early or unwanted pregnancy.
After taking Mifrex Plus Tablet Kit 10's, you may or may not experience vaginal bleeding, which does not indicate complete abortion. Your doctor will examine with the performing ultrasonography to confirm if the abortion is complete.
Do not take Mifrex Plus Tablet Kit 10's, if you have a heart fitted with an artificial valve, heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Mifrex Plus Tablet Kit 10's in these conditions can cause life-threatening conditions in an individual.
Mifrex Plus Tablet Kit 10's does not decrease the chances of survival of your future pregnancy. It is specifically used for the present medical abortion of an early or unwanted pregnancy and does not affect future pregnancies. They will not impact your ability to carry a healthy pregnancy in the future.
Mifrex Plus Tablet Kit 10's is a combination of two medicines: Mifepristone and Misoprostol, which belong to a group of gynaecological medications called Abortifacient. Used for medical abortion to terminate an early or unwanted pregnancy.
Store Mifrex Plus Tablet Kit 10's in a cool, dry place away from sunlight. Keep it out of reach of children.
Mifrex Plus Tablet Kit 10's may cause interaction with certain medications, including corticosteroids, antifungals, antibiotics, anti-epileptics, immunosuppressants, and migraine medications. Taking Mifrex Plus Tablet Kit 10's with these medications may cause negative complications. It's essential to inform your doctor about all medications and health histories you are taking, and they will assess your condition and help manage it to avoid complications.
You should take Mifrex Plus Tablet Kit 10's exactly as directed by your doctor. Your doctor will determine the dose and duration based on your pregnancy status, menstrual cycle, medical history, and especially sexual intimation time history. Follow your doctor's instructions carefully and complete the full course as prescribed for a safe and healthy abortion process.
The common side effects of Mifrex Plus Tablet Kit 10's may include nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Mifrex Plus Tablet Kit 10's subside with time. If these symptoms become worse, please consult a doctor for relief.
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