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Primolut-N Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Primolut-N Tablet:
Taking carbamazepine and Primolut-N Tablet may possibly reduce the effects of Primolut-N Tablet which may result in higher risk of breakthrough bleeding and unexpected pregnancy.

How to manage the interaction:
Although taking carbamazepine and Primolut-N Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Contact your doctor if you experience hot flashes, vaginal dryness, or uncontrolled bleeding. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Primolut-N Tablet:
Coadministration of Primolut-N Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Primolut-N Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Primolut-N Tablet:
Eslicarbazepine may reduce the effects of Primolut-N Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Primolut-N Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
NorethisteroneBexarotene
Severe
How does the drug interact with Primolut-N Tablet:
Coadministration of Bexarotene and Primolut-N Tablet together can decrease the effectiveness of norethindrone and increase the risk of unintended pregnancy.

How to manage the interaction:
Combining Bexarotene with Primolut-N Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneBoceprevir
Severe
How does the drug interact with Primolut-N Tablet:
Using Boceprevir and Primolut-N Tablet together can reduce the blood levels and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Boceprevir with Primolut-N Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, abnormal bleeding, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneFosamprenavir
Severe
How does the drug interact with Primolut-N Tablet:
Using norethindrone together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Taking Primolut-N Tablet with Fosamprenavir together can result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing any symptoms, it's important to reach out to a doctor right away. They can recommend other options that won't interfere with your medication. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Primolut-N Tablet:
Coadministration of Primolut-N Tablet and primidone can reduce the blood levels and effects of Primolut-N Tablet and increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Primolut-N Tablet and Primidone, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Primolut-N Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Primolut-N Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneAmprenavir
Severe
How does the drug interact with Primolut-N Tablet:
Coadministration of Amprenavir and Primolut-N Tablet together may reduce amprenavir effects.

How to manage the interaction:
Combining Amprenavir with Primolut-N Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Primolut-N Tablet:
Using Felbamate and Primolut-N Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Primolut-N Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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