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Progeston 10 mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Progeston 10 mg Tablet:
Coadministration of Progeston 10 mg Tablet with Dabrafenib can reduce the metabolism and decrease the levels of Progeston 10 mg Tablet in the body.

How to manage the interaction:
Taking Progeston 10 mg Tablet with Dabrafenib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of hot flashes, vaginal dryness, or abnormal bleeding, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Progeston 10 mg Tablet:
Coadministration of Progeston 10 mg Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Progeston 10 mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Progeston 10 mg Tablet:
Coadministration of Progeston 10 mg Tablet with Topiramate can reduce the blood levels and effects of norethindrone in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Progeston 10 mg Tablet and topiramate together can result in an interaction; it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, hot flashes or vaginal dryness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Progeston 10 mg Tablet:
Coadministration of Progeston 10 mg Tablet and primidone can reduce the blood levels and effects of Progeston 10 mg Tablet and increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Progeston 10 mg Tablet and Primidone, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Progeston 10 mg Tablet:
Using Etretinate and Progeston 10 mg Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Progeston 10 mg Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
How does the drug interact with Progeston 10 mg Tablet:
Coadministration of Acitretin with Progeston 10 mg Tablet may interfere with the contraceptive effect of Progeston 10 mg Tablet.

How to manage the interaction:
Acitretin and Progeston 10 mg Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.
How does the drug interact with Progeston 10 mg Tablet:
Taking carbamazepine and Progeston 10 mg Tablet may possibly reduce the effects of Progeston 10 mg Tablet which may result in higher risk of breakthrough bleeding and unexpected pregnancy.

How to manage the interaction:
Although taking carbamazepine and Progeston 10 mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Contact your doctor if you experience hot flashes, vaginal dryness, or uncontrolled bleeding. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Progeston 10 mg Tablet:
The combined use of Progeston 10 mg Tablet and phenobarbital can reduce the blood levels and effects of Progeston 10 mg Tablet.

How to manage the interaction:
Although taking phenobarbital and Progeston 10 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Progeston 10 mg Tablet:
Coadministration of Phenytoin and Progeston 10 mg Tablet may decrease the blood levels of Progeston 10 mg Tablet, which may make Progeston 10 mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Progeston 10 mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Progeston 10 mg Tablet:
Eslicarbazepine may reduce the effects of Progeston 10 mg Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Progeston 10 mg Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-10MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-10MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Progeston 10 mg Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Progeston 10 mg Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Progeston 10 mg Tablet dose.

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