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compositionComposition:ELTROMBOPAG-25MG
prescriptionPrescription Medicine
Rebopag 25 mg Tablet 7's
Rebopag 25 mg Tablet 7's
Rebopag 25 mg Tablet 7's
Rebopag 25 mg Tablet 7's
Rebopag 25 mg Tablet 7's

Rebopag 25 mg Tablet is used to treat low platelet count. It contains Eltrombopag which works by causing the cells in the bone marrow to produce more platelets. In some cases, this medicine may cause side effects such as nausea, diarrhea, headache, muscle pain, tiredness, loss of appetite, fever, and cough. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ELTROMBOPAG-25MG

Manufacturer/Marketer :

Msn Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Rebopag 25 mg Tablet

Rebopag 25 mg Tablet is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Rebopag 25 mg Tablet is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused by the hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.

Rebopag 25 mg Tablet contains 'Eltrombopag', which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone, stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Rebopag 25 mg Tablet works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Rebopag 25 mg Tablet helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

In some cases, Rebopag 25 mg Tablet can cause common side effects like nausea, diarrhea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Rebopag 25 mg Tablet or any other medicines before starting Rebopag 25 mg Tablet. Consult the doctor if you are pregnant or planning to conceive. Rebopag 25 mg Tablet is not indicated for use in breastfeeding since it passes into the breast milk.

Uses of Rebopag 25 mg Tablet

Rebopag 25 mg Tablet is used in the treatment of low platelet count (thrombocytopenia) in various blood-related disorders. The detailed uses of Rebopag 25 mg Tablet are as follows:

  • Treats Chronic Immune Thrombocytopenia (ITP): Rebopag 25 mg Tablet is used to treat chronic ITP in patients who have not responded adequately to treatments such as immunoglobulins, corticosteroids, and splenectomy (surgical removal of spleen).
  • Manages Thrombocytopenia in Hepatitis C Virus (HCV) infection: Rebopag 25 mg Tablet helps increase platelet counts in chronic HCV patients, making it safer for them to start and continue treatment with interferon.
  • Treats Severe Aplastic Anaemia (SAA): Rebopag 25 mg Tablet is used for patients with SAA who have not responded to immunosuppressive treatment, helping to stimulate bone marrow to produce more blood cells.
  • Prevents Bleeding Episodes: By increasing platelet count, Rebopag 25 mg Tablet reduces the risk of bleeding associated with low platelet levels in various blood disorders.

Have a query?

Directions for Use

  • Rebopag 25 mg Tablet can be taken on an empty stomach, at least 1 hour before or 2 hours after eating.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Rebopag 25 mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Key Benefits

  • Rebopag 25 mg Tablet contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults.
  • Rebopag 25 mg Tablet works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets.
  • The increase in these bone marrow cells stimulates the production of platelets. Thus Rebopag 25 mg Tablet prevents bleeding episodes by increasing the number of platelets in the blood.

How Rebopag 25 mg Tablet Works

Rebopag 25 mg Tablet contains 'Eltrombopag', which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Rebopag 25 mg Tablet works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Rebopag 25 mg Tablet helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

Storage

Store in a cool and dry place away from sunlight
Side effects of Rebopag 25 mg Tablet
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Rebopag 25 mg Tablet

Take Rebopag 25 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include rash, slowed heartbeat, and excessive tiredness. It may also cause life-threatening blood clots. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are known to be allergic to Rebopag 25 mg Tablet or other medicines, please inform your doctor in advance.
  • Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Rebopag 25 mg Tablet.
  • Take Rebopag 25 mg Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Rebopag 25 mg Tablet.
  • Rebopag 25 mg Tablet is not recommended during pregnancy since it may have harmful effects on the foetus.
  • Consult your doctor before using Rebopag 25 mg Tablet if you are a breastfeeding mother.
  • Do not drive or operate machinery since Rebopag 25 mg Tablet may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive.
  • Avoid or limit alcohol consumption with Rebopag 25 mg Tablet as it may affect the efficacy of Rebopag 25 mg Tablet.
  • Rebopag 25 mg Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

Drug-Drug Interactions

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EltrombopagFerrous gluconate
Critical
EltrombopagFerric maltol
Critical

Drug-Drug Interactions

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EltrombopagFerrous gluconate
Critical
How does the drug interact with Rebopag 25 mg Tablet:
Ferrous gluconate can make Rebopag 25 mg Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Rebopag 25 mg Tablet with Ferrous gluconate is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Rebopag 25 mg Tablet on an empty stomach at least 2 hours before or 4 hours after ferrous gluconate. Do not discontinue any medication without consulting a doctor.
EltrombopagFerric maltol
Critical
How does the drug interact with Rebopag 25 mg Tablet:
Ferric maltol can make Rebopag 25 mg Tablet less effective by reducing its absorption and lowering its concentration in the blood. This can lead to poor treatment outcomes.

How to manage the interaction:
Taking Ferric maltol with Rebopag 25 mg Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Rebopag 25 mg Tablet on an empty stomach at least 2 hours before or 4 hours after ferric maltol. Do not discontinue any medication without consulting a doctor.
EltrombopagMagnesium oxide
Critical
How does the drug interact with Rebopag 25 mg Tablet:
Coadministration of Magnesium oxide with Rebopag 25 mg Tablet can impair the absorption of Rebopag 25 mg Tablet which leads to increased levels in the blood. This can increase the risk and severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Rebopag 25 mg Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EltrombopagAluminium hydroxide
Critical
How does the drug interact with Rebopag 25 mg Tablet:
Coadministration of Rebopag 25 mg Tablet and aluminum hydroxide may interfere with the absorption of Rebopag 25 mg Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Rebopag 25 mg Tablet with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EltrombopagMagnesium citrate
Critical
How does the drug interact with Rebopag 25 mg Tablet:
Taking magnesium citrate with Rebopag 25 mg Tablet can make it less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Taking Magnesium citrate with Rebopag 25 mg Tablet is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take Rebopag 25 mg Tablet on an empty stomach at least 2 hours before or 4 hours after magnesium citrate. Do not discontinue any medication without consulting a doctor.
EltrombopagCalcium chloride
Critical
How does the drug interact with Rebopag 25 mg Tablet:
When Rebopag 25 mg Tablet is mixed with Calcium chloride, the amount of Rebopag 25 mg Tablet in the blood can decrease. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Rebopag 25 mg Tablet with calcium chloride is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EltrombopagInterferon alfacon-1
Severe
How does the drug interact with Rebopag 25 mg Tablet:
Coadministration of Rebopag 25 mg Tablet and Interferon alfacon-1 can increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Rebopag 25 mg Tablet and Interferon alfacon-1 together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
EltrombopagInterferon alfa-2b
Severe
How does the drug interact with Rebopag 25 mg Tablet:
When Interferon alfa-2b is taken with Rebopag 25 mg Tablet, it can lower the metabolism of Rebopag 25 mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Rebopag 25 mg Tablet and Interferon alfa-2b, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to call a doctor right away. These symptoms include chronic hepatitis C, advanced liver disease, cirrhosis, liver failure, and other liver-related problems. You should also seek medical attention if you experience confusion, fever, joint pain, swelling, or any other unusual symptoms. Do not discontinue any medications without consulting a doctor.
EltrombopagCalcium gluconate
Severe
How does the drug interact with Rebopag 25 mg Tablet:
Co-administration of Rebopag 25 mg Tablet and Calcium gluconate may interfere with the absorption of Rebopag 25 mg Tablet and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Rebopag 25 mg Tablet if prescribed by the doctor. However, take Rebopag 25 mg Tablet on an empty stomach, i.e., 2 hours before or 4 hours after taking calcium gluconate. Do not discontinue any medication without consulting a doctor.
EltrombopagPeginterferon alfa-2a
Severe
How does the drug interact with Rebopag 25 mg Tablet:
Combining Rebopag 25 mg Tablet with Peginterferon alfa-2a can lower the metabolism of Rebopag 25 mg Tablet. This can increase the risk or severity of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Rebopag 25 mg Tablet and Peginterferon alfa-2a, but it can be taken if prescribed by a doctor. If you have any of these symptoms like confusion, changes in consciousness, harmful substances in the blood, bleeding from enlarged veins, bleeding, infection of the abdominal wall, complications, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, feeling tired, feeling sick, throwing up, bleeding, pain, dark urine, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat natural and healthy foods by cutting down on fatty and sodium-processed foods.
  • Exercise regularly to maintain good health.
  • Avoid smoking and alcohol intake.
  • Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
  • A high-protein diet, such as lean meat, chicken, crab, turkey, beef and fish, can help increase platelet count.
  • Eating Papayaa is the best natural remedy to increase your platelet count, and you can also use Papayaa leaves mixture.
  • Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
  • Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.

Habit Forming

No

Therapeutic Class

[PLATELET STIMULATING AGENTS]

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Alcohol

Caution

Limit alcohol intake, along with Rebopag 25 mg Tablet, to attain the maximum efficacy of Rebopag 25 mg Tablet and rule out any possibility of worsening of side effects.

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Pregnancy

Unsafe

Rebopag 25 mg Tablet is not recommended in pregnancy. It may affect and harm the developing baby. Please consult your doctor if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Rebopag 25 mg Tablet is excreted into the breast milk. Please consult your doctor for more information before taking Rebopag 25 mg Tablet if you are a nursing mother.

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Driving

Caution

Rebopag 25 mg Tablet may cause dizziness and tiredness affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Rebopag 25 mg Tablet. Rebopag 25 mg Tablet may cause an increase in liver enzymes. Your doctor may start the treatment with a lower dose of Rebopag 25 mg Tablet.

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Kidney

Consult your doctor

Rebopag 25 mg Tablet should be used with caution in cases of renal impairment. It is advised to seek doctor advice before starting Rebopag 25 mg Tablet if you have any kidney problems.

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Children

Caution

Rebopag 25 mg Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Rebopag 25 mg Tablet. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Safe if prescribed

Rebopag 25 mg Tablet is safe for use in elderly patients if prescribed by the physician.

Country of origin

India

Manufacturer/Marketer address

Msn Laboratories Pvt.Ltd., Msn House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, India
Other Info - REB0183

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