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Repace AF Tablet 10's
Repace AF Tablet 10's
Repace AF Tablet 10's
Repace AF Tablet 10's
Repace AF Tablet 10's

Repace AF Tablet is used to treat high blood pressure (hypertension). It contains Losartan and Amlodipine, which lower the blood pressure and increase the blood flow by preventing the narrowing of blood vessels. In some cases, it may cause side effects like sleepiness, taste changes, ankle swelling, headache, dizziness, tiredness, and upset stomach. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Side effects of Repace AF Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to manage angioedema (Swelling Under The Skin) as a side effect of medication:
  • If you experience angioedema, inform your doctor immediately. Treatment can help keep the swelling under control.
  • Seek medical attention if symptoms are severe, such as difficulty breathing or swallowing.
  • Follow your doctor's instructions to manage symptoms, which may include stopping or adjusting the medication that triggered angioedema.
  • Your doctor may also recommend antihistamines, steroids, or other treatments to reduce swelling and inflammation.
  • Make dietary and lifestyle changes as recommended, such as avoiding trigger foods or reducing stress.
  • Monitor your condition closely and track your symptoms to report them to your doctor.
  • Consult your doctor again if symptoms worsen or do not improve or if you experience any new or concerning symptoms.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineRifampicin
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Repace AF Tablet:
Using Repace AF Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Repace AF Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineRifampicin
Severe
How does the drug interact with Repace AF Tablet:
Coadministration of Repace AF Tablet and rifampicin together may lower Repace AF Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Repace AF Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Repace AF Tablet:
Coadministration of Repace AF Tablet with itraconazole may significantly raise the blood levels and effects of Repace AF Tablet.

How to manage the interaction:
Repace AF Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineRifabutin
Severe
How does the drug interact with Repace AF Tablet:
Using Repace AF Tablet and rifabutin together may lower Repace AF Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Repace AF Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenytoin
Severe
How does the drug interact with Repace AF Tablet:
Using Repace AF Tablet and phenytoin together may drastically lower Repace AF Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Repace AF Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Repace AF Tablet:
Using Repace AF Tablet and primidone together may lower Repace AF Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Repace AF Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenobarbital
Severe
How does the drug interact with Repace AF Tablet:
Using phenobarbital and Repace AF Tablet may drastically lower Repace AF Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Repace AF Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineCeritinib
Severe
How does the drug interact with Repace AF Tablet:
Coadministration of Ceritinib together with Repace AF Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Repace AF Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Repace AF Tablet:
Coadministration of Repace AF Tablet and Rifapentine may significantly reduce the blood levels of Repace AF Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Repace AF Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Repace AF Tablet:
Using a combination of Repace AF Tablet and enzalutamide may drastically lower Repace AF Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Repace AF Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+LOSARTAN-50MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+LOSARTAN-50MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Repace AF Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Repace AF Tablet.

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Nov 21, 2025 | 11:22 AM IST

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