Samitib 400 mg Tablet का उपयोग, फायदे ,साइड इफेक्ट,कीमत in Hindi

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Samitib 400 mg Tablet is used to treat cancer. It contains Imatinib which works by inhibiting the growth and spread of cancer cells. In some cases, this medicine may cause side effects such as nausea, vomiting, oedema, fatigue, muscle cramps, musculoskeletal pain, diarrhoea, rash, and abdominal pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

Written By Lakshmithulasi Yarragunta ,

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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Side effects of Samitib 400 mg Tablet

Skin irritation

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Flu

Rest well; get enough sleep. This helps the body fight infection.
Keep yourself hydrated by drinking enough water and other fluids.
Wash your hands often and avoid touching your eyes, mouth or nose.
Wear a mask whilst going out.
Warm steam or a hot shower may help with nose secretions.
Avoid contact with others to prevent contamination.

Weight Gain

Sudden, Involuntary Muscle Contractions

Muscle cramps can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
Warm baths and gentle massage of the affected parts can help relieve cramps.
Avoid strenuous activity and take frequent breaks, as rest is critical.
Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening muscles.
Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for cramps.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Reddening Of The Face

Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Drug-Drug Interactions

ImatinibRegorafenib

Critical

ImatinibVenetoclax

Critical

Drug-Drug Interactions

ImatinibRegorafenib

Critical

How does the drug interact with Samitib 400 mg Tablet:
When Regorafenib is taken with Samitib 400 mg Tablet, it may increase the level of Samitib 400 mg Tablet which may lead to side effects.

How to manage the interaction:
Taking Regorafenib with Samitib 400 mg Tablet is not recommended, it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor.

ImatinibVenetoclax

Critical

How does the drug interact with Samitib 400 mg Tablet:
When Venetoclax is taken with Samitib 400 mg Tablet, Samitib 400 mg Tablet may increase the level of venetoclax which may lead to side effects.

How to manage the interaction:
Taking Samitib 400 mg Tablet with Venetoclax is not recommended, it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor.

ImatinibCobimetinib

Critical

How does the drug interact with Samitib 400 mg Tablet:
When Cobimetinib is taken with Samitib 400 mg Tablet, it can increase the risk of serious side effects.

How to manage the interaction:
Taking Samitib 400 mg Tablet with Cobimetinib is not recommended, but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor.

ImatinibConivaptan

Critical

How does the drug interact with Samitib 400 mg Tablet:
When Samitib 400 mg Tablet is taken with Conivaptan, it can cause increase in the blood levels of conivaptan leading to side effects.

How to manage the interaction:
Taking Samitib 400 mg Tablet with Conivaptan is not recommended, it can be taken if recommended by your doctor. However, if you experience any unusual symptoms, consult the doctor.

ImatinibCisapride

Critical

How does the drug interact with Samitib 400 mg Tablet:
When Samitib 400 mg Tablet is taken with Cisapride, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Samitib 400 mg Tablet with Cisapride is not recommended, it can be taken if a doctor has prescribed this. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.

ImatinibLomitapide

Critical

How does the drug interact with Samitib 400 mg Tablet:
When Lomitapide is taken with Samitib 400 mg Tablet, it can increases levels of lomitapide which may lead to side effects.

How to manage the interaction:
Taking Samitib 400 mg Tablet with Lomitapide is not recommended, but it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor.

ImatinibDihydroergotamine

Critical

How does the drug interact with Samitib 400 mg Tablet:
When Dihydroergotamine is taken with Samitib 400 mg Tablet, it increases levels of dihydroergotamine leading to side effects.

How to manage the interaction:
Taking Samitib 400 mg Tablet with Dihydroergotamine is not recommended, it can be taken if advised by your doctor. However, if you experience any unusual symptoms, consult the doctor.

ImatinibEliglustat

Critical

How does the drug interact with Samitib 400 mg Tablet:
When Samitib 400 mg Tablet is taken with Eliglustat, Samitib 400 mg Tablet increases levels of eliglustat which may lead to side effects.

How to manage the interaction:
Taking Samitib 400 mg Tablet with Eliglustat is not recommended, it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor.

ImatinibIvabradine

Critical

How does the drug interact with Samitib 400 mg Tablet:
Coadministration of Ivabradine with Samitib 400 mg Tablet can increase the levels of Ivabradine in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Ivabradine with Bosutinib together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

ImatinibLurasidone

Critical

How does the drug interact with Samitib 400 mg Tablet:
Using Lurasidone together with Samitib 400 mg Tablet may result in significantly higher Lurasidone blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
Taking Lurasidone with Samitib 400 mg Tablet is not recommended as it leads to an interaction, it can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

IMATINIB-400MGGrapefruit and Grapefruit Juice

Moderate

Drug-Food Interactions

IMATINIB-400MGGrapefruit and Grapefruit Juice

Moderate

Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grapefruit or its juice may increase the blood levels of Samitib 400 mg Tablet which may lead to side effects. Avoid consuming Grapefruit and its juice during treatment with Samitib 400 mg Tablet.

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Author Details

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Dec 24, 2025 | 7:49 AM IST

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समितिब 400 मिलीग्राम टैबलेट 10

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Drug-Drug Interactions