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Drug-Drug Interactions
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Sirotor Tablet:
Coadministration of Sirotor Tablet with posaconazole can lower the levels of Sirotor Tablet in the blood.
How to manage the interaction:
Although there is an interaction between posaconazole with Sirotor Tablet, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Sirotor Tablet with posaconazole can lower the levels of Sirotor Tablet in the blood.
How to manage the interaction:
Although there is an interaction between posaconazole with Sirotor Tablet, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Sirotor Tablet:
Coadministration of Sirotor Tablet with Mifepristone can increase the levels of Sirotor Tablet in the blood, which can increase the risk or severity of side effects.
How to manage the interaction:
Taking Sirotor Tablet with Mifepristone is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.
Coadministration of Sirotor Tablet with Mifepristone can increase the levels of Sirotor Tablet in the blood, which can increase the risk or severity of side effects.
How to manage the interaction:
Taking Sirotor Tablet with Mifepristone is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Sirotor Tablet:
Co-administration of Cidofovir and Sirotor Tablet can increase the risk or severity of Kidney problems.
How to manage the interaction:
Taking Sirotor Tablet with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Co-administration of Cidofovir and Sirotor Tablet can increase the risk or severity of Kidney problems.
How to manage the interaction:
Taking Sirotor Tablet with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
SirolimusBCG vaccine
Critical
How does the drug interact with Sirotor Tablet:
Coadministration of Sirotor Tablet with the BCG vaccine can make the vaccine less effective.
How to manage the interaction:
Taking Sirotor Tablet with the BCG vaccine is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
Coadministration of Sirotor Tablet with the BCG vaccine can make the vaccine less effective.
How to manage the interaction:
Taking Sirotor Tablet with the BCG vaccine is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
Critical
How does the drug interact with Sirotor Tablet:
Coadministration of Sirotor Tablet and Voriconazole can increase blood levels and side effects of Voriconazole.
How to manage the interaction:
Taking Voriconazole with Sirotor Tablet is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
Coadministration of Sirotor Tablet and Voriconazole can increase blood levels and side effects of Voriconazole.
How to manage the interaction:
Taking Voriconazole with Sirotor Tablet is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
Severe
How does the drug interact with Sirotor Tablet:
Co-administration of Sirotor Tablet with Atazanavir can increase the risk or severity of side effects.
How to manage the interaction:
Co-administration of Sirotor Tablet with Atazanavir can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, fever, chills, diarrhea, sore throat, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Sirotor Tablet with Atazanavir can increase the risk or severity of side effects.
How to manage the interaction:
Co-administration of Sirotor Tablet with Atazanavir can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, fever, chills, diarrhea, sore throat, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Sirotor Tablet:
Coadministration of Sirotor Tablet with Clotrimazole may significantly increase the blood levels of Sirotor Tablet. This may increase the risk of serious side effects such as kidney problems, hyperkalemia (high potassium levels in the blood), and high blood pressure.
How to manage the interaction:
Although taking Clotrimazole with Sirotor Tablet may possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
Coadministration of Sirotor Tablet with Clotrimazole may significantly increase the blood levels of Sirotor Tablet. This may increase the risk of serious side effects such as kidney problems, hyperkalemia (high potassium levels in the blood), and high blood pressure.
How to manage the interaction:
Although taking Clotrimazole with Sirotor Tablet may possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
SirolimusEnzalutamide
Severe
How does the drug interact with Sirotor Tablet:
Coadministration of Enzalutamide with Sirotor Tablet may decrease the blood levels of Sirotor Tablet, which may lead to reduced treatment outcomes.
How to manage the interaction:
Although taking Enzalutamide and Sirotor Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medication without consulting a doctor.
Coadministration of Enzalutamide with Sirotor Tablet may decrease the blood levels of Sirotor Tablet, which may lead to reduced treatment outcomes.
How to manage the interaction:
Although taking Enzalutamide and Sirotor Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medication without consulting a doctor.
SirolimusFosphenytoin
Severe
How does the drug interact with Sirotor Tablet:
Coadministration of Sirotor Tablet and Fosphenytoin reduces its levels in the body. This can lead to low treatment outcomes.
How to manage the interaction:
Although there is a possible interaction between Sirotor Tablet and Fosphenytoin, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Coadministration of Sirotor Tablet and Fosphenytoin reduces its levels in the body. This can lead to low treatment outcomes.
How to manage the interaction:
Although there is a possible interaction between Sirotor Tablet and Fosphenytoin, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Sirotor Tablet:
Coadministration of Rifabutin and Sirotor Tablet may significantly reduce the blood levels of Sirotor Tablet, which may make the medication less effective.
How to manage the interaction:
Although there is a possible interaction between Sirotor Tablet and Rifabutin, you can take these medicines together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Rifabutin and Sirotor Tablet may significantly reduce the blood levels of Sirotor Tablet, which may make the medication less effective.
How to manage the interaction:
Although there is a possible interaction between Sirotor Tablet and Rifabutin, you can take these medicines together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking Sirotor Tablet with Grapefruit and Grapefruit juice may increase the side effects of Sirotor Tablet. Avoid or limit consumption of Grapefruit and Grapefruit juice while taking Sirotor Tablet.
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking Sirotor Tablet with Grapefruit and Grapefruit juice may increase the side effects of Sirotor Tablet. Avoid or limit consumption of Grapefruit and Grapefruit juice while taking Sirotor Tablet.
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