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  3. Spylacton-25 mg Tablet 10's

Spylacton-25 mg Tablet 10's, Pack of 10
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Spylacton-25 mg Tablet 10's is used to treat oedema (fluid overload) associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure. It contains Spironolactone, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future. In some cases, this medication may cause common side effects, including low blood pressure, dehydration, drowsiness, dizziness, high potassium levels, low sodium levels, elevated creatinine levels, headaches, breast enlargement in males, and absence of menstrual periods in females. Before taking this medication, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medicines you are taking and any pre-existing medical conditions.

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Side effects of Spylacton-25 mg Tablet
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Practice good hygiene by washing the vaginal area with water and mild soap.
  • Wear breathable cotton underwear and avoid scented products.
  • Check vaginal secretion changes, including colour, texture, amount, and smell.
  • Be aware of potential causes like infection or pregnancy.
  • Consult a doctor if secretions are unusual, or smelly with pain.
  • Vaginal bleeding can be abnormal if it is not related to menstruation, and needs immediate attention and cannot be ignored.
  • Get a physical examination and follow your doctor's instructions to get relief from bleeding.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Prefer practicing yoga and meditation to reduce stress and anxiety, as it can worsen vaginal bleeding.
  • Take a balanced diet and manage your weight.
  • Eat a healthy balanced diet.
  • Reduce stress with relaxation techniques such as yoga or meditation.
  • Keep track of your menstrual cycle any irregularities.
  • Have regular check ups to exclude other health problems.
  • Exercise but do not exercise to the extent of overheating.
  • Hydrate well, eat well (particularly iron and vitamins).
  • If you experience a lack of energy due to liver conditions, consult your doctor to determine the underlying cause and further management.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine instead drink plenty of water.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
SpironolactoneAmiloride
Critical

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
How does the drug interact with Spylacton-25 mg Tablet:
Combining Eplerenone with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Spylacton-25 mg Tablet and eplerenone, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
SpironolactoneAmiloride
Critical
How does the drug interact with Spylacton-25 mg Tablet:
Coadministration of Amiloride with Spylacton-25 mg Tablet may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiloride with Spylacton-25 mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
SpironolactonePotassium citrate
Severe
How does the drug interact with Spylacton-25 mg Tablet:
Taking Spylacton-25 mg Tablet with potassium citrate may increase potassium levels in the blood which can lead to kidney problems and abnormal heart rhythm.

How to manage the interaction:
Although taking Spylacton-25 mg Tablet and potassium citrate together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
SpironolactoneVenetoclax
Severe
How does the drug interact with Spylacton-25 mg Tablet:
Taking Spylacton-25 mg Tablet with venetoclax may significantly increase the blood levels and side effects of venetoclax.

How to manage the interaction:
Although taking Spylacton-25 mg Tablet and azilsartan medoxomil together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, diarrhea, fatigue, anemia (low numbers of blood cells), bleeding problems, and infections. Do not stop using any medications without consulting doctor.
SpironolactoneIrbesartan
Severe
How does the drug interact with Spylacton-25 mg Tablet:
Taking Irbesartan with Spylacton-25 mg Tablet may increase potassium levels in the blood, which may lead to side effects.

How to manage the interaction:
Taking Irbesartan with Spylacton-25 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctors advise.
SpironolactoneColchicine
Severe
How does the drug interact with Spylacton-25 mg Tablet:
Coadministration of colchicine and Spylacton-25 mg Tablet increases blood levels of colchicine and its side effects.

How to manage the interaction:
Although taking Colchicine and Spylacton-25 mg Tablet together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting your doctor.
SpironolactoneValsartan
Severe
How does the drug interact with Spylacton-25 mg Tablet:
Using Spylacton-25 mg Tablet together with valsartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking Spylacton-25 mg Tablet and valsartan together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting a doctor.
SpironolactoneCaptopril
Severe
How does the drug interact with Spylacton-25 mg Tablet:
Combining Spylacton-25 mg Tablet with Captopril may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Taking Captopril with Spylacton-25 mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneLisinopril
Severe
How does the drug interact with Spylacton-25 mg Tablet:
Using lisinopril together with Spylacton-25 mg Tablet may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Taking Lisinopril with Spylacton-25 mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneMorphine
Severe
How does the drug interact with Spylacton-25 mg Tablet:
Taking Spylacton-25 mg Tablet with morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Spylacton-25 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination make sure to contact a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 22, 2025 | 8:59 AM IST

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