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संयोजन :
टोफासिटिनिब-5एमजी
निर्माता/विपणक :
फाइजर लिमिटेड
सेवन का प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
इसके बाद या इसके बाद समाप्त होता है :
Jan-27
Drug-Drug Interactions
TofacitinibStreptozocin
Severe
Drug-Drug Interactions
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How does the drug interact with TFCT NIB Tablet:
Hydroxycarbamide when used with TFCT NIB Tablet may raise the risk of severe infections, cancers.
How to manage the interaction:
There may be a possibility of interaction between hydroxycarbamide with TFCT NIB Tablet, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Hydroxycarbamide when used with TFCT NIB Tablet may raise the risk of severe infections, cancers.
How to manage the interaction:
There may be a possibility of interaction between hydroxycarbamide with TFCT NIB Tablet, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TofacitinibStreptozocin
Severe
How does the drug interact with TFCT NIB Tablet:
Taking TFCT NIB Tablet with Streptozocin may increase the risk of infection.
How to manage the interaction:
Although taking Streptozocin and TFCT NIB Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking TFCT NIB Tablet with Streptozocin may increase the risk of infection.
How to manage the interaction:
Although taking Streptozocin and TFCT NIB Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with TFCT NIB Tablet:
Co-administration of Deflazacort with TFCT NIB Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction between Deflazacort and TFCT NIB Tablet, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Deflazacort with TFCT NIB Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction between Deflazacort and TFCT NIB Tablet, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with TFCT NIB Tablet:
Taking tacrolimus together with TFCT NIB Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and TFCT NIB Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Taking tacrolimus together with TFCT NIB Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and TFCT NIB Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Severe
How does the drug interact with TFCT NIB Tablet:
Taking TFCT NIB Tablet with ritonavir may increase the blood levels of TFCT NIB Tablet.
How to manage the interaction:
Although there is a possible interaction between TFCT NIB Tablet and Ritonavir, but it can be taken together if prescribed by your doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination Do not stop using any medications without a doctor's advice.
Taking TFCT NIB Tablet with ritonavir may increase the blood levels of TFCT NIB Tablet.
How to manage the interaction:
Although there is a possible interaction between TFCT NIB Tablet and Ritonavir, but it can be taken together if prescribed by your doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with TFCT NIB Tablet:
Taking TFCT NIB Tablet with Cladribine may increase the risk of developing serious infections.
How to manage the interaction:
Although taking Cladribine and TFCT NIB Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Taking TFCT NIB Tablet with Cladribine may increase the risk of developing serious infections.
How to manage the interaction:
Although taking Cladribine and TFCT NIB Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
TofacitinibBasiliximab
Severe
How does the drug interact with TFCT NIB Tablet:
Basiliximab can enhance the immune-suppressing effects of TFCT NIB Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between TFCT NIB Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Basiliximab can enhance the immune-suppressing effects of TFCT NIB Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between TFCT NIB Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with TFCT NIB Tablet:
Taking Carfilzomib with TFCT NIB Tablet may increase the risk of serious infections.
How to manage the interaction:
Co-administration of TFCT NIB Tablet with Carfilzomib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Taking Carfilzomib with TFCT NIB Tablet may increase the risk of serious infections.
How to manage the interaction:
Co-administration of TFCT NIB Tablet with Carfilzomib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with TFCT NIB Tablet:
Taking Cyclophosphamide with TFCT NIB Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with TFCT NIB Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Taking Cyclophosphamide with TFCT NIB Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with TFCT NIB Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with TFCT NIB Tablet:
Using TFCT NIB Tablet together with adalimumab can increase the risk of serious infections
How to manage the interaction:
Although taking TFCT NIB Tablet and Adalimumab together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Using TFCT NIB Tablet together with adalimumab can increase the risk of serious infections
How to manage the interaction:
Although taking TFCT NIB Tablet and Adalimumab together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Drug-Food Interactions
TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking TFCT NIB Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with TFCT NIB Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking TFCT NIB Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with TFCT NIB Tablet, as it can lead to an interaction.
Product Substitutes
शराब
सावधानी
यह ज्ञात नहीं है कि शराब TFCT NIB टैबलेट 10's के साथ परस्पर क्रिया करती है या नहीं, इसलिए कृपया डॉक्टर से परामर्श लें।
गर्भावस्था
असुरक्षित
गर्भावस्था के दौरान TFCT NIB टैबलेट 10's नहीं लेना चाहिए। यदि आप गर्भधारण करने योग्य महिला हैं, तो TFCT NIB टैबलेट 10's के साथ उपचार के दौरान और बंद करने के 4 सप्ताह बाद तक प्रभावी गर्भनिरोधक का उपयोग करें।
स्तनपान
असुरक्षित
TFCT NIB टैबलेट 10's लेते समय स्तनपान कराने से बचें। अगर आपको कोई चिंता है तो कृपया डॉक्टर से सलाह लें।
ड्राइविंग
सुरक्षित
आम तौर पर TFCT NIB टैबलेट 10's आपकी गाड़ी चलाने की क्षमता को प्रभावित नहीं करता है। हालाँकि, गाड़ी तभी चलाएँ या मशीनरी का संचालन करें जब आप सतर्क हों।
जिगर
सावधानी
लीवर की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको लीवर की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें। गंभीर लीवर की समस्याओं वाले रोगियों के लिए TFCT NIB टैबलेट 10's की अनुशंसा नहीं की जाती है।
गुर्दा
सावधानी
गुर्दे की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको गुर्दे की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
असुरक्षित
18 साल से कम उम्र के बच्चों के लिए TFCT NIB टैबलेट 10's की अनुशंसा नहीं की जाती है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई थी।
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