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रचना :
टोफासिटिनिब-11एमजी
निर्माता/विपणक :
एमक्योर फार्मास्युटिकल्स लिमिटेड
सेवन का प्रकार :
मौखिक
वापसी नीति :
3 दिन वापसी योग्य
इसके बाद या बाद में समाप्त हो रहा है :
Jan-27
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Tofe-ER Tablet:
Coadministration of Ketoconazole and Tofe-ER Tablet may increase the blood levels and effects of Tofe-ER Tablet which may lead to side effects (low blood cell counts, anemia, serious infections, and elevated blood lipid levels).
How to manage the interaction:
Although taking Ketoconazole and Tofe-ER Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms like paleness, exhaustion, dizziness, fainting, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in the phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning when urinating, consult a doctor. Do not stop using any medications without a doctor's advice.
Coadministration of Ketoconazole and Tofe-ER Tablet may increase the blood levels and effects of Tofe-ER Tablet which may lead to side effects (low blood cell counts, anemia, serious infections, and elevated blood lipid levels).
How to manage the interaction:
Although taking Ketoconazole and Tofe-ER Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms like paleness, exhaustion, dizziness, fainting, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in the phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning when urinating, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tofe-ER Tablet:
Coadministration of methotrexate with Tofe-ER Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of methotrexate with Tofe-ER Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Tofe-ER Tablet:
Taking Etanercept with Tofe-ER Tablet can increase the risk of serious infections as well as sometimes may lead to cancers.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
Taking Etanercept with Tofe-ER Tablet can increase the risk of serious infections as well as sometimes may lead to cancers.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
TofacitinibBoceprevir
Severe
How does the drug interact with Tofe-ER Tablet:
Taking Tofe-ER Tablet with Boceprevir may increases the blood levels of Tofe-ER Tablet which increases risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Tofe-ER Tablet and Boceprevir, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Tofe-ER Tablet with Boceprevir may increases the blood levels of Tofe-ER Tablet which increases risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Tofe-ER Tablet and Boceprevir, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Tofe-ER Tablet:
Taking Carfilzomib with Tofe-ER Tablet may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Tofe-ER Tablet with Carfilzomib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Taking Carfilzomib with Tofe-ER Tablet may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Tofe-ER Tablet with Carfilzomib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
TofacitinibEnzalutamide
Severe
How does the drug interact with Tofe-ER Tablet:
Co-administration of Enzalutamide and Tofe-ER Tablet may decrease the blood levels of Tofe-ER Tablet, which may make Tofe-ER Tablet less effective.
How to manage the interaction:
Although taking Enzalutamide and Tofe-ER Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
Co-administration of Enzalutamide and Tofe-ER Tablet may decrease the blood levels of Tofe-ER Tablet, which may make Tofe-ER Tablet less effective.
How to manage the interaction:
Although taking Enzalutamide and Tofe-ER Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Tofe-ER Tablet:
Taking Tofe-ER Tablet with Docetaxel may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and Docetaxel, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Taking Tofe-ER Tablet with Docetaxel may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and Docetaxel, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Tofe-ER Tablet:
Combining Infliximab with Tofe-ER Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Although taking Tofe-ER Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Combining Infliximab with Tofe-ER Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Although taking Tofe-ER Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tofe-ER Tablet:
Taking Tofe-ER Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Tofe-ER Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
Taking Tofe-ER Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Tofe-ER Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Tofe-ER Tablet:
Taking Tofe-ER Tablet with Nilotinib may increase the risk of infections.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and Nilotinib, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Tofe-ER Tablet with Nilotinib may increase the risk of infections.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and Nilotinib, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofe-ER Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofe-ER Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofe-ER Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofe-ER Tablet, as it can lead to an interaction.
Product Substitutes
शराब
सावधानी
यह ज्ञात नहीं है कि शराब टोफे ईआर टैबलेट 10's के साथ परस्पर क्रिया करती है, इसलिए कृपया डॉक्टर से परामर्श लें।
गर्भावस्था
असुरक्षित
गर्भावस्था के दौरान टोफे ईआर टैबलेट 10's नहीं लेना चाहिए। यदि आप गर्भधारण करने योग्य महिला हैं, तो टोफे ईआर टैबलेट 10's के साथ उपचार के दौरान और बंद करने के 4 सप्ताह बाद तक प्रभावी गर्भनिरोधक का उपयोग करें।
स्तनपान
असुरक्षित
टोफे ईआर टैबलेट 10's लेते समय स्तनपान कराने से बचें। यदि आपको कोई चिंता है तो कृपया डॉक्टर से सलाह लें।
ड्राइविंग
सुरक्षित
आम तौर पर टोफे ईआर टैबलेट 10's आपकी ड्राइव करने की क्षमता को प्रभावित नहीं करता है। हालाँकि, गाड़ी चलाएँ या मशीनरी तभी चलाएँ जब आप सतर्क हों।
जिगर
सावधानी
लीवर की समस्या वाले मरीजों में खुराक समायोजन की आवश्यकता हो सकती है। अगर आपको लीवर की कोई समस्या है या इससे संबंधित कोई चिंता है तो कृपया अपने डॉक्टर से सलाह लें। गंभीर लीवर की समस्या वाले मरीजों के लिए टोफे ईआर टैबलेट 10's की सिफारिश नहीं की जाती है।
गुर्दा
सावधानी
गुर्दे की हानि वाले मरीजों में खुराक समायोजन की आवश्यकता हो सकती है। अगर आपको किडनी की कोई समस्या है या इससे संबंधित कोई चिंता है तो कृपया अपने डॉक्टर से सलाह लें।
बच्चे
असुरक्षित
18 साल से कम उम्र के बच्चों के लिए टोफे ईआर टैबलेट 10's की सिफारिश नहीं की जाती है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई थी।
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