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संयोजन :
टोफासिटिनिब-5एमजी
निर्माता/विपणक :
फाइजर लिमिटेड
सेवन का प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
इसके बाद या इसके बाद समाप्त होता है :
Jan-27
Drug-Drug Interactions
TofacitinibAbatacept
Severe
Severe
Drug-Drug Interactions
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TofacitinibAbatacept
Severe
How does the drug interact with Tofe-5 Tablet:
Using Tofe-5 Tablet together with abatacept can increase the risk of serious infections.
How to manage the interaction:
Taking Abatacept with Tofe-5 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, sore throat, muscle aches, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
Using Tofe-5 Tablet together with abatacept can increase the risk of serious infections.
How to manage the interaction:
Taking Abatacept with Tofe-5 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, sore throat, muscle aches, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tofe-5 Tablet:
Taking Zidovudine with Tofe-5 Tablet may increase the risk of serious infection.
How to manage the interaction:
Although there is a possible interaction between Tofe-5 Tablet and Zidovudine, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Taking Zidovudine with Tofe-5 Tablet may increase the risk of serious infection.
How to manage the interaction:
Although there is a possible interaction between Tofe-5 Tablet and Zidovudine, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Tofe-5 Tablet:
Taking Tofe-5 Tablet with Doxorubicin may increase the risk of serious infection.
How to manage the interaction:
Although taking Tofe-5 Tablet and Doxorubicin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
Taking Tofe-5 Tablet with Doxorubicin may increase the risk of serious infection.
How to manage the interaction:
Although taking Tofe-5 Tablet and Doxorubicin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
TofacitinibBasiliximab
Severe
How does the drug interact with Tofe-5 Tablet:
Basiliximab can enhance the immune-suppressing effects of Tofe-5 Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Tofe-5 Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Basiliximab can enhance the immune-suppressing effects of Tofe-5 Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Tofe-5 Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Tofe-5 Tablet:
Taking Tofe-5 Tablet with Pazopanib may increase the risk of infection.
How to manage the interaction:
Co-administration of Pazopanib with Tofe-5 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Taking Tofe-5 Tablet with Pazopanib may increase the risk of infection.
How to manage the interaction:
Co-administration of Pazopanib with Tofe-5 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Tofe-5 Tablet:
Using Tofe-5 Tablet together with bendamustine may increase the risk of developing serious infections.
How to manage the interaction:
Taking Tofe-5 Tablet with Bendamustine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Using Tofe-5 Tablet together with bendamustine may increase the risk of developing serious infections.
How to manage the interaction:
Taking Tofe-5 Tablet with Bendamustine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tofe-5 Tablet:
Co-administration of Tofe-5 Tablet with Capecitabine may increase the risk of serious and potential infections.
How to manage the interaction:
Although there is an interaction, Capecitabine can be taken with Tofe-5 Tablet if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
Co-administration of Tofe-5 Tablet with Capecitabine may increase the risk of serious and potential infections.
How to manage the interaction:
Although there is an interaction, Capecitabine can be taken with Tofe-5 Tablet if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Tofe-5 Tablet:
When Tofe-5 Tablet is taken with Voriconazole may increase the risk of side effects.
How to manage the interaction:
Although taking Voriconazole and Tofe-5 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, shortness of breath, and pain or burning during urination, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
When Tofe-5 Tablet is taken with Voriconazole may increase the risk of side effects.
How to manage the interaction:
Although taking Voriconazole and Tofe-5 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, shortness of breath, and pain or burning during urination, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tofe-5 Tablet:
Taking Tofe-5 Tablet with Docetaxel may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofe-5 Tablet and Docetaxel, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Taking Tofe-5 Tablet with Docetaxel may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofe-5 Tablet and Docetaxel, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Tofe-5 Tablet:
Using Tofe-5 Tablet together with adalimumab can increase the risk of serious infections
How to manage the interaction:
Although taking Tofe-5 Tablet and Adalimumab together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Using Tofe-5 Tablet together with adalimumab can increase the risk of serious infections
How to manage the interaction:
Although taking Tofe-5 Tablet and Adalimumab together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Drug-Food Interactions
TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofe-5 Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofe-5 Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofe-5 Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofe-5 Tablet, as it can lead to an interaction.
Product Substitutes
शराब
सावधानी
यह ज्ञात नहीं है कि शराब टोफे टैबलेट 10's के साथ परस्पर क्रिया करती है या नहीं, इसलिए कृपया डॉक्टर से परामर्श लें।
गर्भावस्था
असुरक्षित
गर्भावस्था के दौरान टोफे टैबलेट 10's नहीं लेना चाहिए। यदि आप गर्भधारण करने योग्य महिला हैं, तो टोफे टैबलेट 10's के साथ उपचार के दौरान और बंद करने के 4 सप्ताह बाद तक प्रभावी गर्भनिरोधक का उपयोग करें।
स्तनपान
असुरक्षित
टोफे टैबलेट 10's लेते समय स्तनपान कराने से बचें। अगर आपको कोई चिंता है तो कृपया डॉक्टर से सलाह लें।
ड्राइविंग
सुरक्षित
आम तौर पर टोफे टैबलेट 10's आपकी गाड़ी चलाने की क्षमता को प्रभावित नहीं करता है। हालाँकि, गाड़ी तभी चलाएँ या मशीनरी का संचालन करें जब आप सतर्क हों।
जिगर
सावधानी
लीवर की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको लीवर की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें। गंभीर लीवर की समस्याओं वाले रोगियों के लिए टोफे टैबलेट 10's की अनुशंसा नहीं की जाती है।
गुर्दा
सावधानी
गुर्दे की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको गुर्दे की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
असुरक्षित
18 साल से कम उम्र के बच्चों के लिए टोफे टैबलेट 10's की अनुशंसा नहीं की जाती है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई थी।
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