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निर्माता/विपणक :
एमक्योर फार्मास्युटिकल्स लिमिटेड
सेवन प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
इस तारीख को या बाद में समाप्त :
Jan-27
Drug-Drug Interactions
Critical
AtorvastatinLomitapide
Severe
Drug-Drug Interactions
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Critical
How does the drug interact with Tonact 20-EZ Tablet:
Taking Tonact 20-EZ Tablet with Posaconazole can increase the blood levels of Tonact 20-EZ Tablet. This can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between posaconazole with Tonact 20-EZ Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Taking Tonact 20-EZ Tablet with Posaconazole can increase the blood levels of Tonact 20-EZ Tablet. This can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between posaconazole with Tonact 20-EZ Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AtorvastatinLomitapide
Severe
How does the drug interact with Tonact 20-EZ Tablet:
Coadministration of Tonact 20-EZ Tablet with Lomitapide may increase the blood levels of lomitapide.
How to manage the interaction:
There may be a possibility of interaction between Tonact 20-EZ Tablet and Lomitapide, but it can be taken if prescribed by a doctor. Seek immediate medical attention if you develop signs and symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
Coadministration of Tonact 20-EZ Tablet with Lomitapide may increase the blood levels of lomitapide.
How to manage the interaction:
There may be a possibility of interaction between Tonact 20-EZ Tablet and Lomitapide, but it can be taken if prescribed by a doctor. Seek immediate medical attention if you develop signs and symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
AtorvastatinSimeprevir
Severe
How does the drug interact with Tonact 20-EZ Tablet:
Using Tonact 20-EZ Tablet together with simeprevir may significantly increase the blood levels of Tonact 20-EZ Tablet.
How to manage the interaction:
Although taking Tonact 20-EZ Tablet and Simeprevir together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
Using Tonact 20-EZ Tablet together with simeprevir may significantly increase the blood levels of Tonact 20-EZ Tablet.
How to manage the interaction:
Although taking Tonact 20-EZ Tablet and Simeprevir together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tonact 20-EZ Tablet:
Taking Tonact 20-EZ Tablet with rifampicin can decrease the blood levels of Tonact 20-EZ Tablet, which may make the medication less effective.
How to manage the interaction:
Although there is an interaction between Tonact 20-EZ Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Taking Tonact 20-EZ Tablet with rifampicin can decrease the blood levels of Tonact 20-EZ Tablet, which may make the medication less effective.
How to manage the interaction:
Although there is an interaction between Tonact 20-EZ Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tonact 20-EZ Tablet:
When Tonact 20-EZ Tablet and Fluconazole are taken together, the blood levels of Tonact 20-EZ Tablet may be significantly elevated.
How to manage the interaction:
Taking Tonact 20-EZ Tablet in conjunction with Fluconazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
When Tonact 20-EZ Tablet and Fluconazole are taken together, the blood levels of Tonact 20-EZ Tablet may be significantly elevated.
How to manage the interaction:
Taking Tonact 20-EZ Tablet in conjunction with Fluconazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinSaquinavir
Severe
How does the drug interact with Tonact 20-EZ Tablet:
Taking Tonact 20-EZ Tablet with saquinavir may significantly enhance Tonact 20-EZ Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury0.
How to manage the interaction:
Co- administration of Tonact 20-EZ Tablet with saquinavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
Taking Tonact 20-EZ Tablet with saquinavir may significantly enhance Tonact 20-EZ Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury0.
How to manage the interaction:
Co- administration of Tonact 20-EZ Tablet with saquinavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Tonact 20-EZ Tablet:
Using Tonact 20-EZ Tablet together with danazol may significantly increase the blood levels of Tonact 20-EZ Tablet.
How to manage the interaction:
Concomitant administration of Tonact 20-EZ Tablet along with danazol can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop taking any medication without doctor's advice.
Using Tonact 20-EZ Tablet together with danazol may significantly increase the blood levels of Tonact 20-EZ Tablet.
How to manage the interaction:
Concomitant administration of Tonact 20-EZ Tablet along with danazol can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop taking any medication without doctor's advice.
AtorvastatinNelfinavir
Severe
How does the drug interact with Tonact 20-EZ Tablet:
Taking Tonact 20-EZ Tablet with nelfinavir may considerably raise Tonact 20-EZ Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).
How to manage the interaction:
Although taking Tonact 20-EZ Tablet and cyclosporine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
Taking Tonact 20-EZ Tablet with nelfinavir may considerably raise Tonact 20-EZ Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).
How to manage the interaction:
Although taking Tonact 20-EZ Tablet and cyclosporine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Tonact 20-EZ Tablet:
When Gemfibrozil is taken with Tonact 20-EZ Tablet, the chance of side effects such as liver damage and rhabdomyolysis, (an uncommon illness involving the breakdown of skeletal muscle tissue) increases.
How to manage the interaction:
Co-administration of Tonact 20-EZ Tablet along with Gemfibrozil together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
When Gemfibrozil is taken with Tonact 20-EZ Tablet, the chance of side effects such as liver damage and rhabdomyolysis, (an uncommon illness involving the breakdown of skeletal muscle tissue) increases.
How to manage the interaction:
Co-administration of Tonact 20-EZ Tablet along with Gemfibrozil together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinAmprenavir
Severe
How does the drug interact with Tonact 20-EZ Tablet:
Using Tonact 20-EZ Tablet together with amprenavir may significantly increase the blood levels of Tonact 20-EZ Tablet.
How to manage the interaction:
Although taking Tonact 20-EZ Tablet and Amprenavir together can cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these signs - muscle pain, dark urine, fever, or fatigue - make sure to contact a doctor right away. They can help figure out what's going on and how to help you feel better. Do not stop using any medications without talking to a doctor.
Using Tonact 20-EZ Tablet together with amprenavir may significantly increase the blood levels of Tonact 20-EZ Tablet.
How to manage the interaction:
Although taking Tonact 20-EZ Tablet and Amprenavir together can cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these signs - muscle pain, dark urine, fever, or fatigue - make sure to contact a doctor right away. They can help figure out what's going on and how to help you feel better. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Product Substitutes
शराब
असुरक्षित
इस दवा को लेते समय बहुत अधिक शराब न पिएं। बहुत अधिक शराब पीने से आपको मांसपेशियों और लीवर के दुष्प्रभाव होने की संभावना बढ़ सकती है।
गर्भावस्था
असुरक्षित
टोनैक्ट 20-ईज़ेड टैबलेट 10's में एटोरवास्टेटिन होता है जिसकी गर्भावस्था के दौरान अनुशंसा नहीं की जाती है। टोनैक्ट 20-ईज़ेड टैबलेट 10's लेने से पहले अपने चिकित्सक से संपर्क करें।
स्तनपान
सावधानी
टोनैक्ट 20-ईज़ेड टैबलेट 10's लेते समय स्तनपान कराने की सलाह नहीं दी जाती है क्योंकि यह अज्ञात है कि क्या यह टोनैक्ट 20-ईज़ेड टैबलेट 10's स्तन के दूध में गुजरता है। टोनैक्ट 20-ईज़ेड टैबलेट 10's लेने से पहले अपने चिकित्सक से संपर्क करें।
ड्राइविंग
असुरक्षित
टोनैक्ट 20-ईज़ेड टैबलेट 10's का ड्राइव करने और मशीनों का उपयोग करने की क्षमता पर नगण्य प्रभाव पड़ता है।
जिगर
सावधानी
टोनैक्ट 20-ईज़ेड टैबलेट 10's सावधानी के साथ लेना है, खासकर यदि आपको लीवर की बीमारियों/स्थितियों का इतिहास रहा है। आपके डॉक्टर द्वारा खुराक को समायोजित करने की आवश्यकता हो सकती है।
गुर्दा
सावधानी
टोनैक्ट 20-ईज़ेड टैबलेट 10's सावधानी के साथ लेना है, खासकर यदि आपको गुर्दे की बीमारियों/स्थितियों का इतिहास रहा है। आपके डॉक्टर द्वारा खुराक को समायोजित करने की आवश्यकता हो सकती है।
बच्चे
असुरक्षित
टोनैक्ट 20-ईज़ेड टैबलेट 10's बच्चों के लिए अनुशंसित नहीं है क्योंकि टोनैक्ट 20-ईज़ेड टैबलेट 10's की सुरक्षा और प्रभावकारिता स्थापित नहीं हुई है।
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