वार्फरिन-5 टैबलेट 10's का उपयोग, फायदे ,साइड इफेक्ट,कीमत in Hindi

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Warfarin-5 Tablet 10's is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing the formation of a blood clot. It contains Warfarin, which works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. Some people may experience unusual bleeding or skin rash. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions. You must be cautious while shaving and brushing your teeth to avoid too much bleeding from the injury site.

Written By Veda Maddala , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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Drug-Drug Interactions

Drug-Drug Interaction: Warfarin-5 Tablet 10's may have interaction with pain killers (aspirin, ibuprofen, phenylbutazone, feprazone, oxyphenbutazone), antidiabetic drugs (glucagon, tolbutamide, phenformin), heart-related medicines (quinidine, amiodarone, propafenone), antidepressants (nortriptyline, amitriptyline), antifungal drugs (fluconazole, miconazole, ketoconazole), antibiotics (ciprofloxacin, erythromycin, latamoxef, griseofulvin, metronidazole, norfloxacin, rifampicin, sulphonamides, aztreonam, neomycin, cephamandole, co-trimoxazole, chloramphenicol, nalidixic acid, tetracyclines), vitamin K supplements, gout medicine (allopurinol) and sedatives (ethchlorvynol, glutethimide)

Drug-Food Interaction: Warfarin-5 Tablet 10's may interact with cranberry juice, noni juice, grapefruit juice, pomegranate juice, and green tea. Avoid foods rich in vitamin K such as coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, and brussels sprouts as they may affect the activity of Warfarin-5 Tablet 10's. Also, avoid alcohol intake as it may increase the risk of bleeding.

Drug-Disease Interaction: Use with caution in patients with kidney, liver, or bleeding problems, peptic ulcer, and high blood pressure.

WarfarinTamoxifen

Critical

WarfarinDasatinib

Severe

Drug-Drug Interactions

WarfarinTamoxifen

Critical

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Taking tamoxifen with Warfarin-5 Tablet can increase the risk of bleeding.

How to manage the interaction:
Taking Tamoxifen with Warfarin-5 Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience bleeding, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.

WarfarinDasatinib

Severe

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Coadministration of Dasatinib with Warfarin-5 Tablet may, increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Dasatinib and Warfarin-5 Tablet, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without consulting a doctor.

WarfarinStreptokinase

Severe

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Coadministration of Warfarin-5 Tablet with Streptokinase can increase the risk of bleeding.

How to manage the interaction:
Although taking Streptokinase and Warfarin-5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

WarfarinEtodolac

Severe

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Taking Warfarin-5 Tablet together with Etodolac can increase the risk of bleeding.

How to manage the interaction:
Although taking Etodolac and Warfarin-5 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness consult a doctor immediately. Do not stop using any medications without consulting a doctor.

WarfarinIndometacin

Severe

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Using Warfarin-5 Tablet together with Indometacin can increase the risk of bleeding.

How to manage the interaction:
Although taking Indometacin and Warfarin-5 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.

WarfarinOfloxacin

Severe

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Coadministration of Ofloxacin with Warfarin-5 Tablet can increase the risk of bleeding.

How to manage the interaction:
Taking Ofloxacin with Warfarin-5 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

WarfarinMeloxicam

Severe

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Co-administration of Warfarin-5 Tablet with Meloxicam acid can increase the risk of bleeding.

How to manage the interaction:
Although taking Meloxicam acid and Warfarin-5 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.

WarfarinNalidixic acid

Severe

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Coadministration of Warfarin-5 Tablet with Nalidixic acid can increase the risk of bleeding.

How to manage the interaction:
Although taking Nalidixic acid and Warfarin-5 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.

WarfarinErythromycin

Severe

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Coadministration of Erythromycin and Warfarin-5 Tablet together increases the risk of bleeding.

How to manage the interaction:
Although taking erythromycin and Warfarin-5 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness consult a doctor immediately. Do not stop using any medications without consulting a doctor.

WarfarinFlurbiprofen

Severe

How does the drug interact with Warfarin-5 Tablet-5 Tablet:
Taking Warfarin-5 Tablet with Flurbiprofen can increase the risk of bleeding.

How to manage the interaction:
Although taking Flurbiprofen and Warfarin-5 Tablet together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any signs and symptoms of unusual bleeding, like blood in urine, bruising, coughing up or vomiting blood that looks like coffee grounds, or having a severe headache, consult your doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

WARFARIN-5MGVitamin-K rich foods

Moderate

Drug-Food Interactions

WARFARIN-5MGVitamin-K rich foods

Moderate

Common Foods to Avoid:
Avocado, Black Liquorice, Broccoli, Brussels Sprouts, Cabbage, Collard Greens, Coriander, Turnip Greens, Spinach, Green Tea, Kale

How to manage the interaction:
Increasing vitamin K levels in the body can promote clotting and reduce the effectiveness of Warfarin-5 Tablet. Avoid or limit consumption of foods rich in vitamin K while being treated with Warfarin-5 Tablet.

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