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संयोजन :
टोफासिटिनिब-5एमजी
निर्माता/विपणक :
फाइजर लिमिटेड
सेवन का प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
इसके बाद या इसके बाद समाप्त होता है :
Jan-27
Have a query?
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet and bortezomib may increase the risk of infections.
How to manage the interaction:
Although using Bortezomib and Xeljanz 5 mg Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, red or irritated skin, or burning during urination. Do not stop taking any medications without consulting a doctor.
Taking Xeljanz 5 mg Tablet and bortezomib may increase the risk of infections.
How to manage the interaction:
Although using Bortezomib and Xeljanz 5 mg Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, red or irritated skin, or burning during urination. Do not stop taking any medications without consulting a doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Using Xeljanz 5 mg Tablet together with phenytoin may reduce the blood levels and effects of Xeljanz 5 mg Tablet.
How to manage the interaction:
Taking Xeljanz 5 mg Tablet with Phenytoin together can result in an interaction, but it can be taken if your doctor has advised it. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
Using Xeljanz 5 mg Tablet together with phenytoin may reduce the blood levels and effects of Xeljanz 5 mg Tablet.
How to manage the interaction:
Taking Xeljanz 5 mg Tablet with Phenytoin together can result in an interaction, but it can be taken if your doctor has advised it. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Dacarbazine with Xeljanz 5 mg Tablet may increase the risk of serious infection.
How to manage the interaction:
There may be a possibility of interaction between Dacarbazine and Xeljanz 5 mg Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - contact your doctor right away. Do not discontinue any medications without consulting your doctor.
Taking Dacarbazine with Xeljanz 5 mg Tablet may increase the risk of serious infection.
How to manage the interaction:
There may be a possibility of interaction between Dacarbazine and Xeljanz 5 mg Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - contact your doctor right away. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Xeljanz 5 mg Tablet:
Using Xeljanz 5 mg Tablet together with methylprednisolone may increase the risk of serious infections.
How to manage the interaction:
Although taking Methylprednisolone and Xeljanz 5 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or bleeding, consult the doctor. Do not stop using any medications without a doctor's advice.
Using Xeljanz 5 mg Tablet together with methylprednisolone may increase the risk of serious infections.
How to manage the interaction:
Although taking Methylprednisolone and Xeljanz 5 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or bleeding, consult the doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking tacrolimus together with Xeljanz 5 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and Xeljanz 5 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Taking tacrolimus together with Xeljanz 5 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and Xeljanz 5 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet with Cytarabine may increase the risk of serious infection.
How to manage the interaction:
Taking Xeljanz 5 mg Tablet with Cytarabine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Xeljanz 5 mg Tablet with Cytarabine may increase the risk of serious infection.
How to manage the interaction:
Taking Xeljanz 5 mg Tablet with Cytarabine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet with Dactinomycin may increase the risk of serious infection.
How to manage the interaction:
Taking Dactinomycin with Xeljanz 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any complications, infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning when you pee, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
Taking Xeljanz 5 mg Tablet with Dactinomycin may increase the risk of serious infection.
How to manage the interaction:
Taking Dactinomycin with Xeljanz 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any complications, infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning when you pee, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Coadministration of Xeljanz 5 mg Tablet with busulfan may increase the risk of serious infections.
How to manage the interaction:
Taking Busulfan with Xeljanz 5 mg Tablet together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination. Do not discontinue any medications without consulting your doctor.
Coadministration of Xeljanz 5 mg Tablet with busulfan may increase the risk of serious infections.
How to manage the interaction:
Taking Busulfan with Xeljanz 5 mg Tablet together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination. Do not discontinue any medications without consulting your doctor.
TofacitinibTelithromycin
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
When Xeljanz 5 mg Tablet is taken with Telithromycin, it can slow down the way the body breaks down Xeljanz 5 mg Tablet.
How to manage the interaction:
Taking Xeljanz 5 mg Tablet with Telithromycin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
When Xeljanz 5 mg Tablet is taken with Telithromycin, it can slow down the way the body breaks down Xeljanz 5 mg Tablet.
How to manage the interaction:
Taking Xeljanz 5 mg Tablet with Telithromycin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet with Chlorambucil may increase the risk of serious infection.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Chlorambucil, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blo, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Xeljanz 5 mg Tablet with Chlorambucil may increase the risk of serious infection.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Chlorambucil, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blo, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Xeljanz 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Xeljanz 5 mg Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Xeljanz 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Xeljanz 5 mg Tablet, as it can lead to an interaction.
शराब
सावधानी
यह ज्ञात नहीं है कि शराब Xeljanz 5 मिलीग्राम टैबलेट 14's के साथ परस्पर क्रिया करती है या नहीं, इसलिए कृपया डॉक्टर से परामर्श लें।
गर्भावस्था
असुरक्षित
गर्भावस्था के दौरान Xeljanz 5 मिलीग्राम टैबलेट 14's नहीं लेना चाहिए। यदि आप गर्भधारण करने योग्य महिला हैं, तो Xeljanz 5 मिलीग्राम टैबलेट 14's के साथ उपचार के दौरान और बंद करने के 4 सप्ताह बाद तक प्रभावी गर्भनिरोधक का उपयोग करें।
स्तनपान
असुरक्षित
Xeljanz 5 मिलीग्राम टैबलेट 14's लेते समय स्तनपान कराने से बचें। अगर आपको कोई चिंता है तो कृपया डॉक्टर से सलाह लें।
ड्राइविंग
सुरक्षित
आम तौर पर Xeljanz 5 मिलीग्राम टैबलेट 14's आपकी गाड़ी चलाने की क्षमता को प्रभावित नहीं करता है। हालाँकि, गाड़ी तभी चलाएँ या मशीनरी का संचालन करें जब आप सतर्क हों।
जिगर
सावधानी
लीवर की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको लीवर की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें। गंभीर लीवर की समस्याओं वाले रोगियों के लिए Xeljanz 5 मिलीग्राम टैबलेट 14's की अनुशंसा नहीं की जाती है।
गुर्दा
सावधानी
गुर्दे की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको गुर्दे की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
असुरक्षित
18 साल से कम उम्र के बच्चों के लिए Xeljanz 5 मिलीग्राम टैबलेट 14's की अनुशंसा नहीं की जाती है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई थी।
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