Tofatas 5 mg Tablet 10's
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10 ₹212.4
(₹21.24 per unit)
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14 ₹236
(₹16.86 per unit)
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MRP ₹236
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About TOFATAS 5 TABLETS
TOFATAS 5 TABLETS is used to treat rheumatoid arthritis (an autoimmune disease which leads to joint pain and damage), psoriatic arthritis (an inflammatory condition of the joints), and ulcerative colitis (an inflammatory disease of the large intestine).
TOFATAS 5 TABLETS contains Tofacitinib, which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
Not everyone who is taking TOFATAS 5 TABLETS will get these side effects. In some cases, you may experience common side effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
You can take TOFATAS 5 TABLETS with or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.
Avoid taking TOFATAS 5 TABLETS if you are allergic to it. Inform your doctor if you have an active infection, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking TOFATAS 5 TABLETS if you are pregnant or breastfeeding. TOFATAS 5 TABLETS is not recommended for use in children below 18 years as safety and effectiveness have not been established.
Uses of TOFATAS 5 TABLETS
TOFATAS 5 TABLETS is used in the treatment of Rheumatoid arthritis, Psoriatic arthritis, and Ulcerative colitis. The detailed uses of TOFATAS 5 TABLETS are as follows:
- Treatment of Rheumatoid Arthritis: TOFATAS 5 TABLETS helps to manage moderate to severe rheumatoid arthritis by reducing joint pain, inflammation, and slowing disease progression.
- Management of Psoriatic Arthritis: TOFATAS 5 TABLETS treats active psoriatic arthritis by reducing joint pain, swelling, stiffness, and improving overall joint function.
- Treatment of Ulcerative Colitis: TOFATAS 5 TABLETS helps to induce and maintain remission in moderate to severe ulcerative colitis.
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Directions for Use
- TOFATAS 5 TABLETS can be taken with or without food.
- It is recommended to take TOFATAS 5 TABLETS 1-2 times a day, depending on your medical condition, or as prescribed by your doctor.
- Swallow TOFATAS 5 TABLETS as a whole with a glass of water.
- Do not crush, chew, or break it.
Key Benefits
- TOFATAS 5 TABLETS belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
- TOFATAS 5 TABLETS is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).
- This medicine helps lower inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
How TOFATAS 5 TABLETS Works
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- Practice good hygiene by washing hands frequently when touching any wounds.
- Apply creams or lotions to the dry skin and moisturize it.
- Wear the proper clothing and footwear when working outside.
- Cover the wounds with bandage and change it daily.
- Avoid baths at swimming pools, lakes and rivers.
- Drink a lot of water to control diarrhoea and prevent dehydration.
- Avoid spicy, fatty, or high-fiber foods that may irritate the colon.
- Reduce stress through methods such as deep breathing or meditation.
- Include probiotics or supplements containing live bacteria to maintain the health of the gut.
- Quit smoking since smoking makes colitis symptoms worse.
- See your doctor right away if you experience extreme inflammation, bleeding stools, or abdominal pain.
- To promote overall health, drink plenty of water and consume hydrating foods like watermelon and leafy greens.
- Support gut health with probiotic-rich foods such as yoghurt and sauerkraut.
- Eat antioxidant-rich foods like berries and green tea, while limiting sugary drinks, alcohol, and processed foods.
- Additionally, reduce stress through relaxation techniques like deep breathing and meditation.
- Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
- Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
- Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
- Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
- Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
- Monitor UTI symptoms and report any changes to your doctor.
- If antibiotics are prescribed, take them as directed and complete the full course.
What if I have taken an overdose of TOFATAS 5 TABLETS
Drug Warnings
- Do not take TOFATAS 5 TABLETS if you are allergic to any of its components; if you have a severe infection, bloodstream infection, or if you have severe liver problems such as cirrhosis.
- Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, chronic lung disease, liver problems, hepatitis B/C, cancer, inflammation/ulcers of the large intestine, or kidney problems; are planning to get vaccinated; or have heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems.
- If your white blood cell count or red blood cell count is low, avoid taking TOFATAS 5 TABLETS .
- Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties. Inform your doctor about your complete medical and medication history before starting treatment with TOFATAS 5 TABLETS , which helps the physician decide the best treatment plan.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Tofatas 5 mg Tablet with leflunomide can increase the risk of infections.
How to manage the interaction:
Although there is an interaction between leflunomide and Tofatas 5 mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, pain or burning during urination. Do not discontinue any medications without consulting a doctor.
When Tofatas 5 mg Tablet and Clozapine are taken together, that may increase the risk of severe infections.
How to manage the interaction:
There may be a possibility of interaction between Tofatas 5 mg Tablet and Clozapine, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause problems when taken together. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Coadministration of Mycophenolic acid and Tofatas 5 mg Tablet can increase the risk or severity of developing serious infections
How to manage the interaction:
Taking Mycophenolic acid and Tofatas 5 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking Tofatas 5 mg Tablet with ritonavir may increase the blood levels of Tofatas 5 mg Tablet.
How to manage the interaction:
Although there is a possible interaction between Tofatas 5 mg Tablet and Ritonavir, but it can be taken together if prescribed by your doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination Do not stop using any medications without a doctor's advice.
Taking Abemaciclib with Tofatas 5 mg Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Taking Abemaciclib with Tofatas 5 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of rifampicin and Tofatas 5 mg Tablet reduces the blood levels of Tofatas 5 mg Tablet.
How to manage the interaction:
Although taking Rifampicin together with Tofatas 5 mg Tablet can result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
Using Tofatas 5 mg Tablet together with abatacept can increase the risk of serious infections.
How to manage the interaction:
Taking Abatacept with Tofatas 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, sore throat, muscle aches, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Tofatas 5 mg Tablet with cyclosporine may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Tofatas 5 mg Tablet can be taken with ciclosporin if prescribed by the doctor. Consult the prescriber if you experience side effects such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without a doctor's advice.
Coadministration of Tofatas 5 mg Tablet and Gemcitabine can lead to or increase the risk of infection.
How to manage the interaction:
There may be a possibility of interaction between Tofatas 5 mg Tablet and Gemcitabine, but it can be taken if advised by a doctor. Contact your doctor immediately if you develop symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
Taking Tofatas 5 mg Tablet with Pemetrexed may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Pemetrexed and Tofatas 5 mg Tablet, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Drug-Food Interactions
Drug-Food Interactions
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Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofatas 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofatas 5 mg Tablet, as it can lead to an interaction.
Diet & Lifestyle Advise
- Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
- Performing yoga may also help in improving joint flexibility and pain management.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Acupuncture, massage and physical therapy may also be helpful.
- Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
- Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
- Avoid smoking and alcohol consumption.
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Alcohol
Safe if prescribed
It is not known if alcohol interacts with TOFATAS 5 TABLETS , so please consult a doctor.
Pregnancy
Consult your doctor
TOFATAS 5 TABLETS must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with TOFATAS 5 TABLETS and for 4 weeks after discontinuation.
Breast Feeding
Consult your doctor
Avoid breastfeeding while taking TOFATAS 5 TABLETS . Please consult a doctor if you have any concerns.
Driving
Safe if prescribed
TOFATAS 5 TABLETS generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.
Liver
Consult your doctor
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. TOFATAS 5 TABLETS is not recommended for patients with severe liver problems.
Kidney
Consult your doctor
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Safe if prescribed
TOFATAS 5 TABLETS is not recommended for children below 18 years as safety and effectiveness were not established.
Heart
No serious side effects were observed. But it requires careful consideration and monitoring due to increased risks of heart-related problems, particularly in patients with existing cardiovascular risk factors.
Geriatrics
Consult your doctor
No serious adverse effects were observed; however, it requires careful consideration and caution due to the increased risk of certain adverse events, particularly infections.
FAQs
TOFATAS 5 TABLETS is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
TOFATAS 5 TABLETS works by blocking Janus kinase enzyme, thereby lowers inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
Hypertension/high blood pressure could be a side-effect of TOFATAS 5 TABLETS . Consult your doctor before taking TOFATAS 5 TABLETS if you have high blood pressure or if you are taking anti-hypertensive medicines.
Diarrhoea might be a side-effect of TOFATAS 5 TABLETS . Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
TOFATAS 5 TABLETS might impair fertility in females of reproductive potential. It is not known if the effect is reversible. Therefore, talk to a doctor before starting TOFATAS 5 TABLETS if you are trying to become pregnant or if you have any concerns regarding this.
TOFATAS 5 TABLETS affects the immune system and might lower the ability of the immune system to fight infections. Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids.
TOFATAS 5 TABLETS is not recommended for patients with severe liver impairment. Dose adjustment may be needed in patients with mild to moderate liver impairment. Please consult the doctor if you have liver problems.
TOFATAS 5 TABLETS may increase the risk of cancer by changing the way the immune system works. Inform the doctor if you ever had any type of cancer.
TOFATAS 5 TABLETS may begin working within 2-8 weeks after starting the treatment.
TOFATAS 5 TABLETS should not be taken along with tocilizumab as it might increase the risk of infections. Before starting TOFATAS 5 TABLETS , inform the doctor if you are taking tocilizumab.
Prior to starting TOFATAS 5 TABLETS , active or latent tuberculosis test, CBC (complete blood count), LFT (liver function test), and lipid profile tests should be done.
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