apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Tofatas 5 mg Tablet 10's

Tofatas 5 mg Tablet 10's, Pack of 10 TabletS
Tofatas 5 mg Tablet 10's, Pack of 10 TabletS
Offers on medicine orders
All offers
axis icici
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

TOFATAS 5 TABLETS is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It contains Tofacitinib which works by lowering inflammation and symptoms associated with arthritis. In some cases, this medicine may cause side effects such as diarrhoea, headache, upper respiratory tract infection, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

Read more
rxMedicinePrescription drug

Whats That

tooltip

Also Explore

Momverse
Ask Apollo
insurance

Composition :

TOFACITINIB-5MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About TOFATAS 5 TABLETS

TOFATAS 5 TABLETS is used to treat rheumatoid arthritis (an autoimmune disease which leads to joint pain and damage), psoriatic arthritis (an inflammatory condition of the joints), and ulcerative colitis (an inflammatory disease of the large intestine).

TOFATAS 5 TABLETS contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. 

Not everyone who is taking TOFATAS 5 TABLETS will get these side effects. In some cases, you may experience common side effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

You can take TOFATAS 5 TABLETS with or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.

Avoid taking TOFATAS 5 TABLETS if you are allergic to it. Inform your doctor if you have an active infection, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking TOFATAS 5 TABLETS if you are pregnant or breastfeeding. TOFATAS 5 TABLETS is not recommended for use in children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of TOFATAS 5 TABLETS

'TOFATAS 5 TABLETS is used in the treatment of Rheumatoid arthritis, Psoriatic arthritis, and Ulcerative colitis. The detailed uses of TOFATAS 5 TABLETS are as follows:
• Treatment of Rheumatoid Arthritis: TOFATAS 5 TABLETS helps to manage moderate to severe rheumatoid arthritis by reducing joint pain, inflammation, and slowing disease progression.
• Management of Psoriatic Arthritis: TOFATAS 5 TABLETS treats active psoriatic arthritis by reducing joint pain, swelling, stiffness, and improving overall joint function.
• Treatment of Ulcerative Colitis: TOFATAS 5 TABLETS helps to induce and maintain remission in moderate to severe ulcerative colitis.
'

Directions for Use

• TOFATAS 5 TABLETS can be taken with or without food. • It is recommended to take TOFATAS 5 TABLETS 1-2 times a day, depending on your medical condition, or as prescribed by your doctor. • Swallow TOFATAS 5 TABLETS as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

TOFATAS 5 TABLETS belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. 

TOFATAS 5 TABLETS is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).

How TOFATAS 5 TABLETS Works

TOFATAS 5 TABLETS contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tofatas 5 mg Tablet
  • Practice good hygiene by washing hands frequently when touching any wounds.
  • Apply creams or lotions to the dry skin and moisturize it.
  • Wear the proper clothing and footwear when working outside.
  • Cover the wounds with bandage and change it daily.
  • Avoid baths at swimming pools, lakes and rivers.
  • Drink a lot of water to control diarrhoea and prevent dehydration.
  • Avoid spicy, fatty, or high-fiber foods that may irritate the colon.
  • Reduce stress through methods such as deep breathing or meditation.
  • Include probiotics or supplements containing live bacteria to maintain the health of the gut.
  • Quit smoking since smoking makes colitis symptoms worse.
  • See your doctor right away if you experience extreme inflammation, bleeding stools, or abdominal pain.
  • To promote overall health, drink plenty of water and consume hydrating foods like watermelon and leafy greens.
  • Support gut health with probiotic-rich foods such as yoghurt and sauerkraut.
  • Eat antioxidant-rich foods like berries and green tea, while limiting sugary drinks, alcohol, and processed foods.
  • Additionally, reduce stress through relaxation techniques like deep breathing and meditation.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.

What if I have taken an overdose of TOFATAS 5 TABLETS

Take TOFATAS 5 TABLETS only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take TOFATAS 5 TABLETS if you are allergic to any of its components; if you have a severe infection, bloodstream infection, or if you have severe liver problems such as cirrhosis. Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, chronic lung disease, liver problems, hepatitis B/C, cancer, inflammation/ulcers of the large intestine, or kidney problems; are planning to get vaccinated; or have heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems. If your white blood cell count or red blood cell count is low, avoid taking TOFATAS 5 TABLETS .

Avoid taking TOFATAS 5 TABLETS if you are pregnant or breastfeeding. TOFATAS 5 TABLETS is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects. Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties. Inform your doctor about your complete medical and medication history before starting treatment with TOFATAS 5 TABLETS , which helps the physician decide the best treatment plan.

Store TOFATAS 5 TABLETS at room temperature. You are advised not to chew, crush or break the medicine. Keep the medicine out of reach of children. Please do not take more than the recommended dose of medicine, as it can cause undesirable effects. It is always important to check for the expiry of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

verifiedApollotooltip
TofacitinibIfosfamide
Severe
TofacitinibLinezolid
Severe

Drug-Drug Interactions

Login/Sign Up

TofacitinibIfosfamide
Severe
How does the drug interact with Tofatas 5 mg Tablet:
Taking Ifosfamide with Tofatas 5 mg Tablet may increase the risk of serious infection.

How to manage the interaction:
Taking Tofatas 5 mg Tablet with Ifosfamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on your condition. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibLinezolid
Severe
How does the drug interact with Tofatas 5 mg Tablet:
When used with linezolid, Tofatas 5 mg Tablet may raise the risk of serious infections.

How to manage the interaction:
Although taking linezolid and Tofatas 5 mg Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you develop a fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in sputum, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
TofacitinibRifampicin
Severe
How does the drug interact with Tofatas 5 mg Tablet:
Coadministration of rifampicin and Tofatas 5 mg Tablet reduces the blood levels of Tofatas 5 mg Tablet.

How to manage the interaction:
Although taking Rifampicin together with Tofatas 5 mg Tablet can result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
TofacitinibAmprenavir
Severe
How does the drug interact with Tofatas 5 mg Tablet:
Taking Tofatas 5 mg Tablet with amprenavir may increase the blood levels of Tofatas 5 mg Tablet and may increase the risk of infections

How to manage the interaction:
There may be a possibility of interaction between Tofatas 5 mg Tablet and Amprenavir, but it can be taken if prescribed by a doctor. However consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibBoceprevir
Severe
How does the drug interact with Tofatas 5 mg Tablet:
Taking Tofatas 5 mg Tablet with Boceprevir may increases the blood levels of Tofatas 5 mg Tablet which increases risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Tofatas 5 mg Tablet and Boceprevir, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
TofacitinibEnzalutamide
Severe
How does the drug interact with Tofatas 5 mg Tablet:
Co-administration of Enzalutamide and Tofatas 5 mg Tablet may decrease the blood levels of Tofatas 5 mg Tablet, which may make Tofatas 5 mg Tablet less effective.

How to manage the interaction:
Although taking Enzalutamide and Tofatas 5 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
TofacitinibMethylprednisolone
Severe
How does the drug interact with Tofatas 5 mg Tablet:
Using Tofatas 5 mg Tablet together with methylprednisolone may increase the risk of serious infections.

How to manage the interaction:
Although taking Methylprednisolone and Tofatas 5 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or bleeding, consult the doctor. Do not stop using any medications without a doctor's advice.
TofacitinibCapecitabine
Severe
How does the drug interact with Tofatas 5 mg Tablet:
Co-administration of Tofatas 5 mg Tablet with Capecitabine may increase the risk of serious and potential infections.

How to manage the interaction:
Although there is an interaction, Capecitabine can be taken with Tofatas 5 mg Tablet if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
TofacitinibPrednisolone
Severe
How does the drug interact with Tofatas 5 mg Tablet:
Co-administration of Tofatas 5 mg Tablet and Prednisolone can increase the risk of serious infections, diverticular disease (development of small bulges in the lining of the intestine), or gastrointestinal bleeding or perforation.

How to manage the interaction:
Although taking Tofatas 5 mg Tablet and Prednisolone together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in the coughing fluid, weight loss, red or inflamed skin, body sores, pain or burning when urinating, severe abdominal pain, fever, nausea, or vomiting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TofacitinibMycophenolic acid
Severe
How does the drug interact with Tofatas 5 mg Tablet:
Coadministration of Mycophenolic acid and Tofatas 5 mg Tablet can increase the risk or severity of developing serious infections

How to manage the interaction:
Taking Mycophenolic acid and Tofatas 5 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

Login/Sign Up

TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consuming grapefruit products while taking Tofatas 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofatas 5 mg Tablet, as it can lead to an interaction.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIRHEUMATICS, DISEASE MODIFYING ANTIRHEUMATIC DRUGS (DMARDs)

TOFATAS 5 TABLETS Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Caution

It is not known if alcohol interacts with TOFATAS 5 TABLETS , so please consult a doctor.

bannner image

Pregnancy

Unsafe

TOFATAS 5 TABLETS must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with TOFATAS 5 TABLETS and for 4 weeks after discontinuation.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking TOFATAS 5 TABLETS . Please consult a doctor if you have any concerns.

bannner image

Driving

Safe

TOFATAS 5 TABLETS generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. TOFATAS 5 TABLETS is not recommended for patients with severe liver problems.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

TOFATAS 5 TABLETS is not recommended for children below 18 years as safety and effectiveness were not established.

Have a query?

FAQs

TOFATAS 5 TABLETS is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

TOFATAS 5 TABLETS works by blocking Janus kinase enzyme, thereby lowers inflammation and symptoms associated with rheumatoid and psoriatic arthritis.

Hypertension/high blood pressure could be a side-effect of TOFATAS 5 TABLETS . Consult your doctor before taking TOFATAS 5 TABLETS if you have high blood pressure or if you are taking anti-hypertensive medicines.

Diarrhoea might be a side-effect of TOFATAS 5 TABLETS . Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

TOFATAS 5 TABLETS might impair fertility in females of reproductive potential. It is not known if the effect is reversible. Therefore, talk to a doctor before starting TOFATAS 5 TABLETS if you are trying to become pregnant or if you have any concerns regarding this.

TOFATAS 5 TABLETS affects the immune system and might lower the ability of the immune system to fight infections. Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids.

TOFATAS 5 TABLETS is not recommended for patients with severe liver impairment. Dose adjustment may be needed in patients with mild to moderate liver impairment. Please consult the doctor if you have liver problems.

TOFATAS 5 TABLETS may increase the risk of cancer by changing the way the immune system works. Inform the doctor if you ever had any type of cancer.

TOFATAS 5 TABLETS may begin working within 2-8 weeks after starting the treatment.

TOFATAS 5 TABLETS should not be taken along with tocilizumab as it might increase the risk of infections. Before starting TOFATAS 5 TABLETS , inform the doctor if you are taking tocilizumab.

Prior to starting TOFATAS 5 TABLETS , active or latent tuberculosis test, CBC (complete blood count), LFT (liver function test), and lipid profile tests should be done.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TOF0040

Customers Also Bought

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 14, 2025 | 12:59 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.2500.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/203214s018lbl.pdf
  3. https://www.drugs.com/mtm/tofacitinib.html
  4. https://www.ema.europa.eu/en/documents/product-information/xeljanz-epar-product-information_en.pdf
whatsapp Floating Button

Recommended for a 30-day course: 3 Strips

Buy Now
Add 3 Strips