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संयोजन :
टोफासिटिनिब-5एमजी
निर्माता/विपणक :
फाइजर लिमिटेड
सेवन का प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
इसके बाद या इसके बाद समाप्त होता है :
Jan-27
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet with atazanavir may increase the blood levels of Xeljanz 5 mg Tablet. This may lead to cause severe infections.
How to manage the interaction:
Co-administration of Xeljanz 5 mg Tablet with Atazanavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
Taking Xeljanz 5 mg Tablet with atazanavir may increase the blood levels of Xeljanz 5 mg Tablet. This may lead to cause severe infections.
How to manage the interaction:
Co-administration of Xeljanz 5 mg Tablet with Atazanavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking tacrolimus together with Xeljanz 5 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and Xeljanz 5 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Taking tacrolimus together with Xeljanz 5 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and Xeljanz 5 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Using Xeljanz 5 mg Tablet together with dasatinib may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Xeljanz 5 mg Tablet with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
Using Xeljanz 5 mg Tablet together with dasatinib may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Xeljanz 5 mg Tablet with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Cyclophosphamide with Xeljanz 5 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Xeljanz 5 mg Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Taking Cyclophosphamide with Xeljanz 5 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Xeljanz 5 mg Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Using Xeljanz 5 mg Tablet together with phenytoin may reduce the blood levels and effects of Xeljanz 5 mg Tablet.
How to manage the interaction:
Taking Xeljanz 5 mg Tablet with Phenytoin together can result in an interaction, but it can be taken if your doctor has advised it. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
Using Xeljanz 5 mg Tablet together with phenytoin may reduce the blood levels and effects of Xeljanz 5 mg Tablet.
How to manage the interaction:
Taking Xeljanz 5 mg Tablet with Phenytoin together can result in an interaction, but it can be taken if your doctor has advised it. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
TofacitinibAntithymocyte Globulin
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Using Xeljanz 5 mg Tablet together with antithymocyte globulin can increase the risk of serious infections.
How to manage the interaction:
Taking Antithymocyte Globulin with Xeljanz 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.
Using Xeljanz 5 mg Tablet together with antithymocyte globulin can increase the risk of serious infections.
How to manage the interaction:
Taking Antithymocyte Globulin with Xeljanz 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.
TofacitinibEnzalutamide
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Co-administration of Enzalutamide and Xeljanz 5 mg Tablet may decrease the blood levels of Xeljanz 5 mg Tablet, which may make Xeljanz 5 mg Tablet less effective.
How to manage the interaction:
Although taking Enzalutamide and Xeljanz 5 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
Co-administration of Enzalutamide and Xeljanz 5 mg Tablet may decrease the blood levels of Xeljanz 5 mg Tablet, which may make Xeljanz 5 mg Tablet less effective.
How to manage the interaction:
Although taking Enzalutamide and Xeljanz 5 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet with Doxorubicin may increase the risk of serious infection.
How to manage the interaction:
Although taking Xeljanz 5 mg Tablet and Doxorubicin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
Taking Xeljanz 5 mg Tablet with Doxorubicin may increase the risk of serious infection.
How to manage the interaction:
Although taking Xeljanz 5 mg Tablet and Doxorubicin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
TofacitinibBasiliximab
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Basiliximab can enhance the immune-suppressing effects of Xeljanz 5 mg Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Basiliximab can enhance the immune-suppressing effects of Xeljanz 5 mg Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Clarithromycin may boost the blood levels of Xeljanz 5 mg Tablet, increasing side effects such as low blood cell count, anemia, serious infections, and elevated blood lipid levels.
How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Xeljanz 5 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Clarithromycin may boost the blood levels of Xeljanz 5 mg Tablet, increasing side effects such as low blood cell count, anemia, serious infections, and elevated blood lipid levels.
How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Xeljanz 5 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Xeljanz 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Xeljanz 5 mg Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Xeljanz 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Xeljanz 5 mg Tablet, as it can lead to an interaction.
Product Substitutes
शराब
सावधानी
यह ज्ञात नहीं है कि शराब Xeljanz 5 मिलीग्राम टैबलेट 14's के साथ परस्पर क्रिया करती है या नहीं, इसलिए कृपया डॉक्टर से परामर्श लें।
गर्भावस्था
असुरक्षित
गर्भावस्था के दौरान Xeljanz 5 मिलीग्राम टैबलेट 14's नहीं लेना चाहिए। यदि आप गर्भधारण करने योग्य महिला हैं, तो Xeljanz 5 मिलीग्राम टैबलेट 14's के साथ उपचार के दौरान और बंद करने के 4 सप्ताह बाद तक प्रभावी गर्भनिरोधक का उपयोग करें।
स्तनपान
असुरक्षित
Xeljanz 5 मिलीग्राम टैबलेट 14's लेते समय स्तनपान कराने से बचें। अगर आपको कोई चिंता है तो कृपया डॉक्टर से सलाह लें।
ड्राइविंग
सुरक्षित
आम तौर पर Xeljanz 5 मिलीग्राम टैबलेट 14's आपकी गाड़ी चलाने की क्षमता को प्रभावित नहीं करता है। हालाँकि, गाड़ी तभी चलाएँ या मशीनरी का संचालन करें जब आप सतर्क हों।
जिगर
सावधानी
लीवर की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको लीवर की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें। गंभीर लीवर की समस्याओं वाले रोगियों के लिए Xeljanz 5 मिलीग्राम टैबलेट 14's की अनुशंसा नहीं की जाती है।
गुर्दा
सावधानी
गुर्दे की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको गुर्दे की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
असुरक्षित
18 साल से कम उम्र के बच्चों के लिए Xeljanz 5 मिलीग्राम टैबलेट 14's की अनुशंसा नहीं की जाती है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई थी।
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