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संयोजन :
टोफासिटिनिब-5एमजी
निर्माता/विपणक :
फाइजर लिमिटेड
सेवन का प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
इसके बाद या इसके बाद समाप्त होता है :
Jan-27
Drug-Drug Interactions
Severe
Drug-Drug Interactions
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How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Xeljanz 5 mg Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
Taking Xeljanz 5 mg Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Xeljanz 5 mg Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Etanercept with Xeljanz 5 mg Tablet can increase the risk of serious infections as well as sometimes may lead to cancers.
How to manage the interaction:
Although there is a possible interaction between Xeljanz 5 mg Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
Taking Etanercept with Xeljanz 5 mg Tablet can increase the risk of serious infections as well as sometimes may lead to cancers.
How to manage the interaction:
Although there is a possible interaction between Xeljanz 5 mg Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
TofacitinibBasiliximab
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Basiliximab can enhance the immune-suppressing effects of Xeljanz 5 mg Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Basiliximab can enhance the immune-suppressing effects of Xeljanz 5 mg Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
TofacitinibNelfinavir
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
When Xeljanz 5 mg Tablet is taken with Nelfinavir, that may increase the risk of side effects.
How to manage the interaction:
Although taking Xeljanz 5 mg Tablet and Nelfinavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
When Xeljanz 5 mg Tablet is taken with Nelfinavir, that may increase the risk of side effects.
How to manage the interaction:
Although taking Xeljanz 5 mg Tablet and Nelfinavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Abemaciclib with Xeljanz 5 mg Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Taking Abemaciclib with Xeljanz 5 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Abemaciclib with Xeljanz 5 mg Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Taking Abemaciclib with Xeljanz 5 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
When Xeljanz 5 mg Tablet and Clozapine are taken together, that may increase the risk of severe infections.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Clozapine, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause problems when taken together. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
When Xeljanz 5 mg Tablet and Clozapine are taken together, that may increase the risk of severe infections.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Clozapine, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause problems when taken together. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet with Thiotepa may increase the risk of infection.
How to manage the interaction:
Co-administration of Thiotepa with Xeljanz 5 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Xeljanz 5 mg Tablet with Thiotepa may increase the risk of infection.
How to manage the interaction:
Co-administration of Thiotepa with Xeljanz 5 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Using Xeljanz 5 mg Tablet together with daratumumab may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction between Xeljanz 5 mg Tablet and Daratumumab, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Using Xeljanz 5 mg Tablet together with daratumumab may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction between Xeljanz 5 mg Tablet and Daratumumab, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet with phenobarbital, may decrease Xeljanz 5 mg Tablet blood levels and effects.
How to manage the interaction:
Although taking phenobarbital and Xeljanz 5 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
Taking Xeljanz 5 mg Tablet with phenobarbital, may decrease Xeljanz 5 mg Tablet blood levels and effects.
How to manage the interaction:
Although taking phenobarbital and Xeljanz 5 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Xeljanz 5 mg Tablet:
Taking Xeljanz 5 mg Tablet with Procarbazine may increase the risk of severe infection.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Procarbazine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Taking Xeljanz 5 mg Tablet with Procarbazine may increase the risk of severe infection.
How to manage the interaction:
There may be a possibility of interaction between Xeljanz 5 mg Tablet and Procarbazine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Drug-Food Interactions
TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Xeljanz 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Xeljanz 5 mg Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Xeljanz 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Xeljanz 5 mg Tablet, as it can lead to an interaction.
Product Substitutes
शराब
सावधानी
यह ज्ञात नहीं है कि शराब Xeljanz 5 मिलीग्राम टैबलेट 14's के साथ परस्पर क्रिया करती है या नहीं, इसलिए कृपया डॉक्टर से परामर्श लें।
गर्भावस्था
असुरक्षित
गर्भावस्था के दौरान Xeljanz 5 मिलीग्राम टैबलेट 14's नहीं लेना चाहिए। यदि आप गर्भधारण करने योग्य महिला हैं, तो Xeljanz 5 मिलीग्राम टैबलेट 14's के साथ उपचार के दौरान और बंद करने के 4 सप्ताह बाद तक प्रभावी गर्भनिरोधक का उपयोग करें।
स्तनपान
असुरक्षित
Xeljanz 5 मिलीग्राम टैबलेट 14's लेते समय स्तनपान कराने से बचें। अगर आपको कोई चिंता है तो कृपया डॉक्टर से सलाह लें।
ड्राइविंग
सुरक्षित
आम तौर पर Xeljanz 5 मिलीग्राम टैबलेट 14's आपकी गाड़ी चलाने की क्षमता को प्रभावित नहीं करता है। हालाँकि, गाड़ी तभी चलाएँ या मशीनरी का संचालन करें जब आप सतर्क हों।
जिगर
सावधानी
लीवर की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको लीवर की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें। गंभीर लीवर की समस्याओं वाले रोगियों के लिए Xeljanz 5 मिलीग्राम टैबलेट 14's की अनुशंसा नहीं की जाती है।
गुर्दा
सावधानी
गुर्दे की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको गुर्दे की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
असुरक्षित
18 साल से कम उम्र के बच्चों के लिए Xeljanz 5 मिलीग्राम टैबलेट 14's की अनुशंसा नहीं की जाती है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई थी।
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