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Gemsoline Softgel Capsule is used to treat low blood calcium levels. It increases calcium levels and provides essential nutrients that help maintain bone health. In some cases, this medicine may cause side effects such as constipation or stomach upset, nausea, vomiting, loss of appetite, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Gemsoline Softgel Capsule
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

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Drug-Drug Interactions

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Drug-Drug Interactions: Gemsoline Softgel Capsule may interact with anti-cancer medication (estramustine), cholesterol-lowering agent (cholestyramine), medicine used to treat heart problems (digitalis), medicines to treat bacterial infections (ciprofloxacin, levofloxacin, gatifloxacin, sparfloxacin, ofloxacin), and antifungal (ketoconazole).

Drug-Food Interactions: Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.

Drug-Disease Interactions: Inform your doctor if you have myeloma, bone metastases, primary hyperparathyroidism, Nephrolithiasis/nephrocalcinosis, renal failure, or hypervitaminosis D.

Drug-Drug Interactions

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How does the drug interact with Gemsoline Softgel Capsule:
Co-administration of Orlistat with Calcitriol may reduce the levels of Calcitriol which can lead to low treatment outcomes.

How to manage the interaction:
Although there is an interaction, Calcitriol can be taken with Orlistat when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gemsoline Softgel Capsule:
Co-administration of Calcium carbonate may lower the effectiveness of Patiromer calcium in binding potassium.

How to manage the interaction:
Although there is an interaction, Calcium carbonate can be taken with Patiromer calcium if prescribed by the doctor. Consult the prescriber if you experience symptoms such as metabolic alkalosis like nausea, vomiting, tremor, muscle twitching, lightheadedness, numbness or tingling, prolonged muscle spasms, slowed breathing, irregular heartbeat, and confusion. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Gemsoline Softgel Capsule:
Co-administration of Rifapentine with Calcitriol may decrease the effects of Calcitriol.

How to manage the interaction:
Although there is an interaction, Calcitriol can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Gemsoline Softgel Capsule:
Taking Calcitriol with Fosphenytoin can reduce the levels and efficacy of Calcitriol.

How to manage the interaction:
Taking Calcitriol with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Gemsoline Softgel Capsule:
Co-administration of metolazone with calcitriol +Calcium carbonate can cause blood calcium levels to become too high.

How to manage the interaction:
Although there is an interaction, calcitriol+Calcium carbonate can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Gemsoline Softgel Capsule:
Co-administration of Calcitriol with Dihydrotachysterol can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Dihydrotachysterol with Calcitriol can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gemsoline Softgel Capsule:
Co-administration of calcitriol and burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Gemsoline Softgel Capsule:
Co-administration of calcitriol + calcium carbonate with digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, calcitriol + calcium carbonate can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, a slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Gemsoline Softgel Capsule:
Co-administration of Paricalcitol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.

How to manage the interaction:
Concomitant use of Paricalcitol with Calcitriol can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Gemsoline Softgel Capsule:
Co-administration of Calcitriol with Carbamazepine may decrease the effects of Calcitriol.

How to manage the interaction:
Although there is an interaction, Calcitriol can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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CALCITRIOL-0.25MG+CALCIUM CARBONATE-200MG+ZINC-7.5MGFiber rich foods, Potassium rich foods
Moderate

Drug-Food Interactions

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CALCITRIOL-0.25MG+CALCIUM CARBONATE-200MG+ZINC-7.5MGFiber rich foods, Potassium rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
foods high in oxalic acid (spinach) may decrease calcium absorption. Consider taking calcium at least 2 hours before or after eating meals high in oxalic acid or phytic acid.

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