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  3. Istamet D-XR 500 Tablet Substitute

Istamet D-XR 500 Tablet Substitute

Medicine Composition:

DAPAGLIFLOZIN-10MG + METFORMIN-500MG + SITAGLIPTIN-100MG

All Substitutes & Brand Comparisons

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When Should You Consider Switching from Istamet D-XR 500 Tablet?

Patients may explore substitutes in the following scenarios:

  • High monthly cost of Istamet D-XR 500 Tablet
  • Non-availability in local pharmacies
  • Generic recommendation by a doctor
  • Side effects or better tolerability with alternatives

What to Know Before Switching

Before you switch from Istamet D-XR 500 Tablet to another medicine, here are some important points to keep in mind:

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Same salt, different brands:

Most substitutes contain the same active ingredient - DAPAGLIFLOZIN-10MG + METFORMIN-500MG + SITAGLIPTIN-100MG, but the fillers, coating, or manufacturing quality may vary slightly.

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Consult your doctor first:

Even if the salt is the same, your doctor can confirm if the substitute is right for your condition, dosage, and health history.

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Watch out for allergies or reactions:

Some people may react differently to certain brands due to inactive ingredients. If you notice any side effects, inform your doctor immediately.

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Price ≠ effectiveness:

A lower-priced substitute doesn't mean it's less effective. Many generic medicines work just as well as branded ones.

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Check the dosage form and strength:

Always match the substitute’s strength (e.g., 5mg, 10mg) and form (tablet, capsule, syrup) with what your doctor prescribed.

Uses

Istamet D-XR 500 Tablet is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Istamet D-XR 500 Tablet are as follows:

  • Type 2 Diabetes Management: Istamet D-XR 500 Tablet is used to improve blood sugar control in adults with type 2 diabetes. It combines three agents that work together to reduce glucose production, enhance insulin response, and promote glucose excretion through urine.
  • Cardiovascular and Kidney Protection: Istamet D-XR 500 Tablet helps lower the risk of heart failure and diabetic kidney disease by improving vascular function, reducing albuminuria, and supporting healthy blood pressure levels.
  • Weight and Metabolic Control: Istamet D-XR 500 Tablet supports weight loss and improves metabolic health by reducing excess glucose and enhancing insulin sensitivity, making it beneficial for overweight or obese diabetic patients.
  • HbA1c Reduction and Glycemic Stability: Istamet D-XR 500 Tablet effectively lowers HbA1c levels and helps maintain steady blood sugar throughout the day, reducing the risk of hypoglycemia and long-term complications.

Medicinal Benefits

  • Istamet D-XR 500 Tablet is a combination of three antidiabetic medicines: Sitagliptin, Dapagliflozin, and Metformin, used in the management of Type 2 Diabetes Mellitus, along with proper diet and exercise.
  • Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps increase insulin release and decrease glucagon levels in the body, lowering blood sugar levels when they are high.
  • Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, works by removing excess glucose through the urine, thereby lowering blood sugar levels.
  • Metformin is a biguanide which reduces the amount of sugar produced by the liver and delays glucose absorption from the intestine.
  • It improves the body’s sensitivity to insulin, promoting better glucose uptake by muscles and tissues.
  • The combined effect of these three drugs offers multi-targeted control of blood sugar levels, especially in patients not controlled by single or dual therapy.
  • Istamet D-XR 500 Tablet helps manage blood glucose levels and prevents diabetes-related complications, such as eye problems, nerve problems, and kidney impairment.

FAQs

The substitutes of Istamet D-XR 500 Tablet contain the same active salt(s) - DAPAGLIFLOZIN-10MG + METFORMIN-500MG + SITAGLIPTIN-100MG. However, they may differ in price, manufacturing quality, and inactive ingredients. Speak to your doctor to find a suitable option.

Switching to a generic substitute medicine in the place of Istamet D-XR 500 Tablet is often possible if it has the same salt, strength, and dosage form. But always check with your doctor before making any changes to your medication.

Generics versions of Istamet D-XR 500 Tablet are typically more affordable because they don’t include the original brand's research, development, and marketing costs. They contain the same active ingredient and are approved for safety and effectiveness.

Most people don’t notice any difference. However, some may react to different fillers or coatings. If you notice any unusual symptoms after switching, consult your doctor.

Make sure the new medicine has the same active salt, strength, dosage form. Always confirm the change with your doctor or pharmacist.

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