RXDr Reddy's Laboratories Ltd
₹14.5
(₹2.61/ 1gm)
RXUSV Pvt Ltd
₹132.5
(₹3.98/ 1gm)

Patients may explore substitutes in the following scenarios:
Before you switch from Nise Gel to another medicine, here are some important points to keep in mind:
Same salt, different brands:
Most substitutes contain the same active ingredient - CAPSAICIN-0.25MG + MENTHOL-50MG + METHYL SALICYLATE-100MG + NIMESULIDE-10MG, but the fillers, coating, or manufacturing quality may vary slightly.
Consult your doctor first:
Even if the salt is the same, your doctor can confirm if the substitute is right for your condition, dosage, and health history.
Watch out for allergies or reactions:
Some people may react differently to certain brands due to inactive ingredients. If you notice any side effects, inform your doctor immediately.
Price ≠ effectiveness:
A lower-priced substitute doesn't mean it's less effective. Many generic medicines work just as well as branded ones.
Check the dosage form and strength:
Always match the substitute’s strength (e.g., 5mg, 10mg) and form (tablet, capsule, syrup) with what your doctor prescribed.
Nise Gel is used in the treatment of Musculoskeletal pain. The detailed uses of Nise Gel are as follows:
Nise Gel is a combination of three painkillers/analgesics (Nimesulide, Capsaicin, Methyl salicylate) and one cooling agent (Menthol). Nimesulide and Methyl salicylate belong to the class of non-steroidal anti-inflammatory drug (NSAIDs) or painkillers that works by blocking the release of certain chemical messengers in the brain responsible for causing pain and symptoms of inflammation such as redness and swelling. Capsaicin is an analgesic that works by affecting the chemical messenger in the brain (neurotransmitter) that transmits pain signals to the brain, thereby reducing the perception of pain. Menthol acts as a cooling agent that relieves pain initially by cooling the skin, followed by warming it up. Cooling and warming up distracts from the pain and helps improve blood circulation.
The substitutes of Nise Gel contain the same active salt(s) - CAPSAICIN-0.25MG + MENTHOL-50MG + METHYL SALICYLATE-100MG + NIMESULIDE-10MG. However, they may differ in price, manufacturing quality, and inactive ingredients. Speak to your doctor to find a suitable option.
Switching to a generic substitute medicine in the place of Nise Gel is often possible if it has the same salt, strength, and dosage form. But always check with your doctor before making any changes to your medication.
Generics versions of Nise Gel are typically more affordable because they don’t include the original brand's research, development, and marketing costs. They contain the same active ingredient and are approved for safety and effectiveness.
Most people don’t notice any difference. However, some may react to different fillers or coatings. If you notice any unusual symptoms after switching, consult your doctor.
Make sure the new medicine has the same active salt, strength, dosage form. Always confirm the change with your doctor or pharmacist.
Substitutes of Nise Gel meet the same safety and efficacy standards as Nise Gel, but small differences in absorption or formulation can exist. A doctor can help you choose the right one for your needs.
Yes. Substitutes of Nise Gel may vary in color, size, or shape due to differences in manufacturing and branding, but this does not affect how they work.
Yes, it’s generally safe to switch between multiple substitutes of Nise Gel if they have the same salt and strength. However, always inform your doctor so they can monitor how your body responds.
Yes, many people safely use substitutes of Nise Gel for long-term treatment. Just ensure it’s done under medical supervision.
If your symptoms stay under control or lab results remain stable, the substitute for Nise Gel is likely working well. Regular follow-ups with your doctor are important.
Absolutely. Even with the same salt, small differences can affect how your body responds when switching from Nise Gel to its substitute. Always consult your doctor before switching.
Nise Gel is used to relieve joint pain, low back pain, muscle sprain and sports injuries. Besides this, it also reduces pain and swelling in conditions like osteoarthritis and rheumatoid arthritis.
Nise Gel is a combination of four painkillers/analgesics: Nimesulide, Capsaicin, Methyl salicylate and one cooling agent (Menthol). Nimesulide and Methyl salicylate works by blocking the release of certain chemical messengers in the brain responsible for causing pain and symptoms of inflammation such as redness and swelling. Capsaicin works by affecting the chemical messenger in the brain (neurotransmitter) that transmits pain signals to the brain, thereby reducing the perception of pain. Menthol acts as a cooling agent that relieves pain initially by cooling the skin, followed by warming it up. Cooling and warming up distracts from the pain and helps improve blood circulation.
You are recommended to avoid using Nise Gel if you have had any recent bypass heart surgery, heart attack, stroke, gastrointestinal bleeding (bloody stool), or ulcer of the stomach or intestine. Elderly (more than 65 years of age) or smokers are at greater risk of having gastrointestinal bleeding, so they should use Nise Gel with caution.
No, you are not recommended to apply Nise Gel on wounds, cuts, burn, rash, infected areas or peeling skin. However, please consult a doctor before using Nise Gel.
Yes, Nise Gel may cause skin irritation at the site of application as a common side effect. It is not necessary for everyone using Nise Gel to experience this side effect. However, if the irritation persists or worsens, please consult a doctor.
Patients with heart failure are not advised to take Nise Gel because painkillers may alter blood substance levels and make blood clots more likely. These blood clots have the potential to block and constrict your heart's artery, leading to a heart attack.
You are recommended to take a shower, bathe or wash the treated area of skin after 1 hour of applying Nise Gel for effective results.
No, Nise Gel does not cure arthritis. Nise Gel is only used to relieve symptoms of arthritis-like joint pain, swelling and stiffness.
Nise Gel is for external use only. Take a small amount of Nise Gel on the finger and apply as a thin layer on the clean and dry affected area and surrounding skin. Avoid contact with the eyes, mouth, or nose. If accidental contact occurs, rinse thoroughly with water. Be sure to wash your hands before and after application.
No, Nise Gel, is not a steroid. It belongs to the class of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).
While using Nise Gel, you are recommended to tell your doctor if you are allergic to the active substances of Nise Gel and if you have kidney, liver, or heart disease, diabetes, asthma, high blood pressure, bleeding in the stomach or intestines, stomach ulcers, and edema. Avoid using Nise Gel on cuts, wounds, or damaged skin. Avoid consuming alcohol while using it to reduce the risk of stomach bleeding. Do not apply heat or tightly wrap the treated area. Use only as directed, and avoid excessive or prolonged application to prevent adverse effects.
If you forget to use Nise Gel, then apply as soon as you remember. Avoid applying more to make up for the missed one. If you have any concerns, contact your doctor.
You are not recommended to stop using Nise Gel without consulting your doctor, even if you feel better as stopping early might affect the treatment's effectiveness. Always follow your doctor’s instructions.
Nise Gel is generally safe for most patients when used as per the dose and duration advised by a doctor. Follow the instructions given by your doctor. Do not self-medicate.
No, Nise Gel is not an antibiotic. It contains capsaicin, menthol methyl salicylate, and nimesulide as its active substances, used to relieve pain and inflammation associated with conditions like muscle aches, joint pain, and sprains.
Both Nise Gel and paracetamol are pain-relieving medications. Using them together is generally not advised, as it may raise the risk of gastric ulcers and bleeding. It is essential to consult your doctor before taking Nise Gel with paracetamol or other medicines.
No, Nise Gel does not contain aspirin.
Nise Gel may be used for headaches, but only when prescribed by a doctor. It has been shown to help with mild migraines and can be effective for headaches when used as directed. However, it is not recommended for long-term use in cases of recurring headaches. If you experience frequent headaches, consult your doctor for proper treatment.
Nise Gel does not cause drowsiness as it works locally and applied to the skin. Nise Gel active ingredients work directly on the area to relieve pain. Inform your doctor if your symptoms worsen while using Nise Gel.
You are recommended to consult your doctor before using Nise Gel with other medicines.
Nise Gel may be taken with aspirin as no interactions have been observed. However, please consult a doctor before using Nise Gel with aspirin or other medicines to avoid potential interactions.
No, Nise Gel is not banned in India.
It is unknown if Nise Gel passes into breast milk and if it can harm the baby. Therefore, consult a doctor before using Nise Gel if you are breastfeeding.
You are recommended to take a doctor’s advice before using Nise Gel if you are pregnant or planning for pregnancy.
Nise Gel may be safe for asthma patients. However, it's advisable to inform your doctor if you have a history of asthma. Do not self-medicate.
Nise Gel causes side effects such as irritated skin, burning sensation, stinging sensation, red skin or rashes, erythema (redness of skin or mucous membranes), and desquamation (peeling skin). Consult your doctor if these side effects persist or worsen.
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