4D PLUS TABLET
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About 4D PLUS TABLET
4D PLUS TABLET is used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. 4D PLUS TABLET does not work against infections caused by the virus, including cold and flu.
4D PLUS TABLET is a combination of four anti-tuberculosis drugs: Rifampicin, isoniazid, pyrazinamide and ethambutol. Isoniazid prevents the formation of the bacterial cell wall. At the same time, rifampicin inactivates a bacterial enzyme (RNA-polymerase), which is required by TB bacteria (Mycobacterium tuberculosis) to make essential proteins and to reproduce. Ethambutol and pyrazinamide work by slowing the growth of bacteria. Altogether, they kill the bacteria and treat the infection.
The dose and duration of 4D PLUS TABLET can vary depending on your condition and the severity of the infection. In some cases, you may experience certain common side effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), fatigue and vision problems. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer, while taking 4D PLUS TABLET as they might cause interaction. Maintain a gap of one hour between 4D PLUS TABLET and antacid medicines. Consult your doctor before taking 4D PLUS TABLET if you are pregnant. Avoid breastfeeding while taking 4D PLUS TABLET as it passes into breast milk. 4D PLUS TABLET is not recommended for use in children. 4D PLUS TABLET may cause dizziness and vision problems, so drive only if you are alert. Avoid consuming alcohol along with 4D PLUS TABLET as it might lead to liver problems and increased dizziness.
Uses of 4D PLUS TABLET
4D PLUS TABLET is used in the treatment of Tuberculosis (TB). The detailed uses of 4D PLUS TABLET are as follows:
- Tuberculosis Treatment: 4D PLUS TABLET is primarily prescribed as a first-line treatment for tuberculosis (TB), targeting infections caused by Mycobacterium tuberculosis.
- Management of Drug-Resistant Tuberculosis: In specific cases, 4D PLUS TABLET may be included in treatment regimens for drug-resistant TB, under strict medical supervision.
- Supportive Treatment: 4D PLUS TABLET may also be used to address secondary infections that develop during tuberculosis treatment, aiding in overall health recovery.
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Directions for Use
- 4D PLUS TABLET should be taken on an empty stomach, at least 30 minutes before food or 2 hours after eating.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow 4D PLUS TABLET as a whole with a glass of water.
- Do not crush, break, or chew it.
Key Benefits
4D PLUS TABLET belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. 4D PLUS TABLET is a combination of four anti-tuberculosis drugs: Rifampicin, isoniazid, pyrazinamide and ethambutol. Isoniazid prevents the formation of the bacterial cell wall. At the same time, rifampicin inactivates a bacterial enzyme (RNA-polymerase), which is required by TB bacteria (Mycobacterium tuberculosis) to make essential proteins and reproduce. Ethambutol and pyrazinamide work by slowing the growth of bacteria. Altogether, they kill the bacteria and treat the infection.
How 4D PLUS TABLET Works
Storage
- If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
- Use compression socks and make sure to rest for a while to get relief from pain.
- Avoid smoking and intake of alcohol or fluids that aggravate the pain.
- Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
What if I have taken an overdose of 4D PLUS TABLET
Drug Warnings
Do not take 4D PLUS TABLET if you are allergic to any of its contents, if you have jaundice or if you are taking HIV medicines (saquinavir or ritonavir). Before starting 4D PLUS TABLET, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult your doctor before taking 4D PLUS TABLET if you are pregnant. Avoid breastfeeding while taking 4D PLUS TABLET as it passes into breast milk. 4D PLUS TABLET is not recommended for use in children. 4D PLUS TABLET may cause dizziness and vision problems, so drive with caution. Avoid consuming alcohol along with 4D PLUS TABLET as it might lead to liver problems and increased dizziness.
Drug-Drug Interactions
Drug-Drug Interactions
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When 4d Plus Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.
How to manage the interaction:
Taking Regorafenib with 4d Plus Tablet is not recommended, it taken can be taken if prescribed by the doctor.
When Lovastatin is taken with 4d Plus Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).
How to manage the interaction:
Taking 4d Plus Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
When Lomitapide is taken with 4d Plus Tablet, 4d Plus Tablet may increase the blood levels of lomitapide which leads to side effects.
How to manage the interaction:
Taking 4d Plus Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
Taking saquinavir with 4d Plus Tablet can increase the risk or severity of side effects.
How to manage the interaction:
Although there is an interaction between pyrazinamide and 4d Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
When Indinavir is taken with 4d Plus Tablet, it can reduce the blood levels and effects of Indinavir.
How to manage the interaction:
Although there is an interaction between indinavir and 4d Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Voriconazole with 4d Plus Tablet can increase blood level of Voriconazole.
How to manage the interaction:
Although there is an interaction between Voriconazole with 4d Plus Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
When ranolazine is taken with 4d Plus Tablet, it can reduce the blood levels and effects of ranolazine.
How to manage the interaction:
Although there is an interaction between ranolazine and 4d Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking pirfenidone with 4d Plus Tablet can reduce the levels and effects of pirfenidone
How to manage the interaction:
Although there is an interaction between pirfenidone and 4d Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking darunavir with 4d Plus Tablet can decrease the blood levels of darunavir, which may make the medication less effective.
How to manage the interaction:
Although there is an interaction between darunavir and 4d Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
When BCG vaccine is used with 4d Plus Tablet, its effectiveness may be reduced.
How to manage the interaction:
Although there is a possible interaction between 4d Plus Tablet and BCG vaccine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
- Foods rich in vitamin C such as kiwi, broccoli and bell pepper helps in improving the immune system.
- Avoid processed and fried foods.
- Warm ginger tea or warm soup can help in providing relief from cough.
- Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.
- Quit smoking and avoid alcohol consumption.
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Alcohol
Safe if prescribed
Avoid alcohol consumption while taking 4D PLUS TABLET as it could lead to increased dizziness and liver damage.
Pregnancy
Consult your doctor
Please consult your doctor if you are pregnant, your doctor will prescribe 4D PLUS TABLET only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
4D PLUS TABLET passes into breast milk. Do not breastfeed while taking 4D PLUS TABLET. Consult your doctor for further advice.
Driving
Safe if prescribed
4D PLUS TABLET may cause dizziness, vision problems, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.
Liver
Consult your doctor
Dose adjustment may be needed. Please consult your doctor before taking 4D PLUS TABLET if you have liver impairment/liver disease.
Kidney
Consult your doctor
Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.
Children
Safe if prescribed
4D PLUS TABLET is not recommended for use in children.
Heart
4D PLUS TABLET can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.
Geriatrics
Consult your doctor
4D PLUS TABLET should be given to elderly patients only if recommended by a doctor. Please consult your doctor before using 4D PLUS TABLET.
FAQs
4D PLUS TABLET belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as kidneys, brain, spine and bone marrow.
4D PLUS TABLET is a combination of four anti-tuberculosis drugs, namely: Rifampicin, isoniazid, pyrazinamide, and ethambutol. 4D PLUS TABLET works by killing the bacteria named Mycobacterium tuberculosis which causes TB (tuberculosis).
Do not stop taking 4D PLUS TABLET despite symptomatic relief. To treat your condition effectually, continue taking 4D PLUS TABLET for as long as it has been prescribed for you.
Do not take 4D PLUS TABLET along with antacids as it might decrease the effectiveness of 4D PLUS TABLET. Maintain a minimum gap of 1 hour between both. However, please consult your doctor before taking other medicines with 4D PLUS TABLET.
Consult your doctor before taking 4D PLUS TABLET with other medicines. Your doctor would suggest the right time, dose and precautions before taking 4D PLUS TABLET with other drugs.
4D PLUS TABLET contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer. Avoid these foods while taking 4D PLUS TABLET.
4D PLUS TABLET might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking 4D PLUS TABLET. Consult your doctor if you have any concerns regarding this, your doctor may suggest an alternate method of contraception.
4D PLUS TABLET may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva or tears. The colour in tears may last for some time even after you stop taking 4D PLUS TABLET. Do not worry as it is a common side-effect of 4D PLUS TABLET.
Yes, 4D PLUS TABLET might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking 4D PLUS TABLET.
4D PLUS TABLET may affect test results of some blood tests such as tests for folate, vitamin B12 and liver function. Inform the person doing the tests that you are taking 4D PLUS TABLET.
Yes, 4D PLUS TABLET may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking 4D PLUS TABLET to check how your liver is functioning.
Take 4D PLUS TABLET as directed by your doctor. Take 4D PLUS TABLET on an empty stomach, either one hour before eating or two hours after a meal. Swallow it as whole with a glass of water; do not crush, chew, or break it.
You are recommended to avoid alcohol while taking 4D PLUS TABLET, as it may cause headache, sweating, dizziness, and feeling lightheaded or faint. Please, consult the doctor if you have any concerns.
Yes, 4D PLUS TABLET may cause visual impairment (blurred vision, loss of vision). This condition may affect the patient's ability to drive or operate machinery safely. However, if you notice any changes in your vision, stop taking 4D PLUS TABLET and inform your doctor immediately.
Store 4D PLUS TABLET at a temperature below 30°C in a cool and dry place as advised on the label. Protect from light and moisture. Keep it out of reach of children. 4D PLUS TABLET should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.
4D PLUS TABLET causes side effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), and fatigue. However, please contact a doctor if these side effects persist longer.
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