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compositionComposition:ETHAMBUTOL+ISONIAZID+PYRAZINAMIDE+RIFAMPICIN
prescription
Prescription Medicine
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4D Tablet is used to treat tuberculosis. It works by preventing the growth of bacteria or killing bacteria. In some cases, you may experience certain common side effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), fatigue and vision problems. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ETHAMBUTOL+ISONIAZID+PYRAZINAMIDE+RIFAMPICIN

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About 4D Tablet

The medicine 4D Tablet is a prescription oral tablet used to treat active tuberculosis, a serious bacterial infection that primarily affects the lungs. Its main medical purpose is to eliminate the tuberculosis bacteria from your body, preventing the disease from spreading or worsening. By targeting the bacteria at multiple stages of growth, it helps you recover safely and completely.

To get the best results, you must take 4D Tablet daily and consistently at the same time every day to keep a steady level of medicine in your body. It is best to take this medicine on an empty stomach, either one hour before or two hours after meals. Additionally, avoiding alcohol completely and eating nutrient-rich foods will significantly support your recovery.

While taking 4D Tablet, you may notice some common, harmless side effects, such as your urine, saliva, or tears turning a temporary red-orange colour. However, you must contact your doctor immediately if you experience serious side effects like yellowing of your skin or eyes, severe stomach pain, or changes in your vision.

Before starting this treatment, tell your doctor if you have a history of liver disease, kidney problems, gout, or eye conditions. Do not take this if you have severe liver damage or are known to be allergic to any of the active components in this medicine.

This medicine can interact with alcohol, raising the risk of severe liver damage, and it can make certain medications, like hormonal birth control, much less effective. If you are pregnant, breastfeeding, or an older adult, you must talk to your doctor or pharmacist to ensure this treatment is safe for your specific situation.

Uses of 4D Tablet

4D Tablet is used to treat tuberculosis. The detailed uses of 4D Tablet are as follows:

  • Active Tuberculosis (TB): 4D Tablet is prescribed to treat active tuberculosis infections in the lungs and other parts of the body. It works by stopping the growth, multiplication, and spread of the bacteria causing the infection.

Key Benefits

4D Tablet helps treat tuberculosis effectively by combining multiple anti-tuberculosis medicines into a single formulation. This comprehensive approach targets the bacteria in different stages of growth, helping control the infection and supporting successful recovery.

  • Simplifies Tuberculosis Treatment: By combining four essential tuberculosis medicines into one tablet, 4D Tablet reduces the number of pills you need to take each day. This simplified treatment approach can help improve adherence to therapy and support better treatment outcomes.
  • Helps Relieve Tuberculosis Symptoms: As the bacterial infection comes under control, symptoms such as persistent cough, fever, night sweats, fatigue, and weight loss gradually improve, helping you regain strength and return to your daily activities.
  • Helps Prevent Drug Resistance: Using multiple anti-tuberculosis medicines together helps reduce the risk of the bacteria developing resistance to treatment. This supports the effectiveness of therapy throughout the full treatment course and helps prevent the spread of resistant strains.

Directions for Use

To get the full benefit of this medication and ensure it works properly, follow these step-by-step instructions:

  • Take 4D Tablet on an empty stomach, either 1 hour before or 2 hours after a meal, as food can significantly reduce how much of the medicine your body absorbs.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, break, or dissolve the tablet.
    Take your dose at the exact same time every day to keep a constant amount of the medicine in your bloodstream.
  • Continue taking this medicine for the entire duration prescribed by your doctor, even if your symptoms clear up and you start feeling better. Stopping early can cause the infection to return and make the bacteria resistant to treatment.
  • Always follow your doctor's exact instructions regarding your treatment plan. If you have questions about how to take this medication, talk to your doctor or pharmacist.

How 4D Tablet Works

The medicine 4D Tablet combines four active ingredients, rifampicin, isoniazid, pyrazinamide and ethambutol, that work in harmony to attack and destroy tuberculosis bacteria from multiple angles. Rifampicin stops the bacteria from reproducing by blocking its genetic copying machinery, specifically preventing it from making essential proteins. Isoniazid targets the outer defences of the bacteria by blocking the production of mycolic acids, which are critical building blocks for the bacterial cell wall. Without a strong wall, the bacteria die. Pyrazinamide specifically targets bacteria living in highly acidic environments inside your body's immune cells. It disrupts their energy production, weakening them so they cannot survive. Ethambutol works by interfering with the synthesis of another key structural component of the bacterial cell wall, stopping the bacteria from multiplying and growing. By attacking the bacteria's genetic material, cell wall structure, and energy production simultaneously, 4D Tablet ensures that even dormant or hard-to-reach bacteria are successfully eliminated.
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Alcohol

Unsafe

Avoid alcohol consumption while taking 4D Tablet as it could lead to increased dizziness and liver damage.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe 4D Tablet only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

4D Tablet passes into breast milk. Do not breastfeed while taking 4D Tablet. Consult your doctor for further advice.

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Driving

Unsafe

4D Tablet may cause dizziness, vision problems, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking 4D Tablet if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Unsafe

4D Tablet is not recommended for use in children.

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Heart

Caution

4D Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

4D Tablet should be given to elderly patients only if recommended by a doctor. Please consult your doctor before using 4D Tablet.

What if I have taken an overdose of 4D Tablet

Do not take more than the prescribed dose of 4D Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid alcohol entirely: Alcohol significantly increases the risk of severe liver damage when combined with 4D Tablet.
  • Take vitamin B6: Ask your doctor if you should take a pyridoxine (vitamin B6) supplement. This is often recommended to prevent nerve tingling or numbness in your hands and feet while on this medication.
  • Limit high-tyramine and high-histamine foods: Avoid eating aged cheeses, red wine, cured meats, yeast extracts, and certain fish like tuna or mackerel. Combining these foods with your medicine can trigger a reaction causing headaches, sweating, a fast heartbeat, or flushing.
  • Eat a nutrient-dense diet: Focus on high-protein foods, fresh vegetables, and whole grains to help your body rebuild tissue, boost your immune system, and recover from the infection.
  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys safely filter and clear the medication from your system.
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Have a query?

How Soon It Starts Working

The time required for 4D Tablet to start to work: The time required for 4D Tablet to show its action is unknown. The time for which the effects of 4D Tablet last: The duration of action for 4D Tablet is unknown.

What if you forget to take 4D Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store 4D Tablet at room temperature, strictly between 15°C and 30°C (59°F to 86°F). • Keep the tablets in their original blister packaging or container to protect them from light and moisture.

Drug Warnings

  • Do not wear soft contact lenses while taking this medicine, as it can permanently stain them a red-orange colour. Switch to glasses during your treatment.
  • If you use hormonal birth control (such as pills, patches, or rings), use a reliable non-hormonal barrier method like condoms, because 4D Tablet makes hormonal contraceptives much less effective.
  • Attend all scheduled doctor appointments for regular blood tests to check your liver function and for regular eye exams to monitor your vision.
  • Do not take antacids containing aluminium or magnesium within 2 hours of taking your medication, as they can stop your body from absorbing 4D Tablet properly.
  • Always inform any healthcare provider, including your dentist, surgeon, or laboratory technician, that you are taking 4D Tablet, as it can interfere with certain medical test results.

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Before using 4D Tablet, it is important to understand how it may interact with other medicines, foods, or existing health conditions.

Drug-Drug Interactions

  • Oral blood thinners (e.g., warfarin): 4D Tablet may reduce the effectiveness of certain anticoagulants, potentially affecting blood clotting control. Your doctor may recommend closer monitoring and dose adjustments if these medicines are used together.
  • Heart medicines (e.g., digoxin, beta-blockers): This medicine may alter the blood levels or effectiveness of certain cardiovascular medications. Regular monitoring may be required to ensure optimal treatment response.
  • Anti-seizure medicines: Some anticonvulsants may have reduced effectiveness when taken with 4D Tablet, which could affect seizure control. Inform your doctor if you are receiving treatment for epilepsy or other seizure disorders.
  • Antifungal medicines: 4D Tablet may lower the blood levels of certain antifungal medications, potentially reducing their effectiveness in treating fungal infections.
  • Oral diabetes medicines: This medicine may affect the levels or effectiveness of some medicines used to control blood sugar, requiring closer monitoring of glucose levels during treatment.
  • Pain relievers: Certain analgesics may become less effective when taken with 4D Tablet. Consult your healthcare provider before starting any new pain medication.
  • Other medicines that may affect the liver (e.g., high-dose paracetamol/acetaminophen): Using these medicines together may increase the risk of liver-related side effects or liver damage. Your doctor may recommend additional monitoring if combination therapy is necessary.

Drug-Food Interactions

  • Foods high in tyramine (e.g., aged cheeses, soy sauce): Consuming large amounts of tyramine-rich foods while taking 4D Tablet may increase the risk of flushing, headaches, rapid heartbeats, or changes in blood pressure.
  • Foods high in histamine (e.g., tuna, mackerel, yeast-containing products): These foods may increase the likelihood of symptoms such as flushing, headache, palpitations, or discomfort in susceptible individuals.

Drug-Disease Interaction

  • Liver disease: Patients with pre-existing liver impairment may be at increased risk of adverse effects and may require closer monitoring during treatment.
  • Kidney disease: Reduced kidney function may affect how your body processes and eliminates 4D Tablet, potentially increasing the risk of side effects. Dose adjustments or additional monitoring may be necessary.
  • Gout: This medicine may increase uric acid levels in the blood, which can trigger gout attacks or worsen existing gout symptoms.
  • Diabetes: 4D Tablet may affect blood glucose control. Patients with diabetes should monitor their blood sugar levels regularly and consult their doctor if they notice significant changes in glucose readings.

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Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

4D Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as kidneys, brain, spine and bone marrow.
4D Tablet is a combination of four anti-tuberculosis drugs, namely: Rifampicin, isoniazid, pyrazinamide, and ethambutol. 4D Tablet works by killing the bacteria named Mycobacterium tuberculosis which causes TB (tuberculosis).
Do not stop taking 4D Tablet despite symptomatic relief. To treat your condition effectually, continue taking 4D Tablet for as long as it has been prescribed for you.
Do not take 4D Tablet along with antacids as it might decrease the effectiveness of 4D Tablet. Maintain a minimum gap of 1 hour between both. However, please consult your doctor before taking other medicines with 4D Tablet.
Consult your doctor before taking 4D Tablet with other medicines. Your doctor would suggest the right time, dose and precautions before taking 4D Tablet with other drugs.
4D Tablet contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer. Avoid these foods while taking 4D Tablet.
4D Tablet might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking 4D Tablet. Consult your doctor if you have any concerns regarding this, your doctor may suggest an alternate method of contraception.
4D Tablet may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva or tears. The colour in tears may last for some time even after you stop taking 4D Tablet. Do not worry as it is a common side-effect of 4D Tablet.
Yes, 4D Tablet might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking 4D Tablet.
4D Tablet may affect test results of some blood tests such as tests for folate, vitamin B12 and liver function. Inform the person doing the tests that you are taking 4D Tablet.
Yes, 4D Tablet may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking 4D Tablet to check how your liver is functioning.
Take 4D Tablet as directed by your doctor. Take 4D Tablet on an empty stomach, either one hour before eating or two hours after a meal. Swallow it as whole with a glass of water; do not crush, chew, or break it.
You are recommended to avoid alcohol while taking 4D Tablet, as it may cause headache, sweating, dizziness, and feeling lightheaded or faint. Please, consult the doctor if you have any concerns.
Yes, 4D Tablet may cause visual impairment (blurred vision, loss of vision). This condition may affect the patient's ability to drive or operate machinery safely. However, if you notice any changes in your vision, stop taking 4D Tablet and inform your doctor immediately.
Store 4D Tablet at a temperature below 30°C in a cool and dry place as advised on the label. Protect from light and moisture. Keep it out of reach of children. 4D Tablet should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.
4D Tablet causes side effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), and fatigue. However, please contact a doctor if these side effects persist longer.
This is a very common and harmless side effect of one of the active ingredients in the medicine. It causes a reddish-orange discolouration of body fluids, including urine, saliva, sweat, tears, and stool. This will go away once you complete your treatment. Talk to your doctor if you have concerns.
One of the components of this medicine can cause a temporary deficiency of vitamin B6, which can lead to nerve problems like tingling, burning, or numbness in your hands and feet. Taking a daily vitamin B6 (pyridoxine) supplement helps prevent this side effect. Talk to your doctor or pharmacist for a specific recommendation.

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Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - 4DT0001
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