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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Abitate 250 mg Tablet is an anti-androgen medicine used to treat prostate cancer. It contains Abiraterone, which is in a class of medications called androgen biosynthesis inhibitors. It works by decreasing the amount of certain hormones in the body. Common side effects of Abitate 250 mg Tablet may include nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain.

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Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Abitate 250 mg Tablet

Abitate 250 mg Tablet is an anti-androgen medicine used in the treatment of prostate cancer. It is used to treat metastatic castration-resistant prostate cancer (a condition where cancer does not get controlled with hormonal therapy) and metastatic castration-sensitive prostate cancer (a condition where cancer has spread to other parts of the body but can be controlled) in men. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc.

Abitate 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Abitate 250 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. 

Abitate 250 mg Tablet may cause certain side effects such as nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite and groin pain. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor. Take this medicine as advised by your doctor. It should be taken on an empty stomach at least 2 hours before or after meals. Your doctor will decide the dose of the medicine based on the severity of your disease.

Abitate 250 mg Tablet should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention before taking Abitate 250 mg Tablet . Abitate 250 mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. Inform your doctor of all your ongoing medications to avoid interactions. This medicine is used in combination with prednisolone for the treatment of prostate cancer. 

Uses of Abitate 250 mg Tablet

Abitate 250 mg Tablet is used to treat prostate cancer. The detailed uses of Abitate 250 mg Tablet are as follows:

  • Manages advanced prostate cancer: Abitate 250 mg Tablet is used in combination with prednisone to treat prostate cancer that has spread to other parts of the body.
  • Helps lower hormone levels: Abitate 250 mg Tablet reduces the production of certain hormones that fuel the growth of prostate cancer cells.

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Directions for Use

  • Abitate 250 mg Tablet can be taken on an empty stomach at least two hours before or after a meal as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Abitate 250 mg Tablet as a whole with a glass of water.
  • Do not break, chew or crush Abitate 250 mg Tablet .

Medicinal Benefits

Abitate 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes increase of cancer cells in prostate gland. Abitate 250 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. Abitate 250 mg Tablet is used in combination with prednisolone for the treatment of prostate cancer. It is mainly intended for use in men only.

How Abitate 250 mg Tablet Works

Abitate 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Abitate 250 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

Storage

• Store in a cool and dry place away from sunlight.• Keep Abitate 250 mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Abitate 250 mg Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Exercise for at least 30 minutes most days of the week.
  • Limit alcohol consumption.
  • Consider a low carbohydrate diet that limits grains, starchy vegetables and fruit. Include foods rich in protein and fat.
  • Avoid excess sugar, fatty foods and carbohydrates.
  • Aim for weight loss as it helps to improve cardiovascular health and minimize the risk of complications related to obesity.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Abitate 250 mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Abitate 250 mg Tablet may include fast or irregular heartbeat, lightheadedness, dizziness, or fainting, shortness of breath or difficulty breathing, swelling of the feet, ankles, or lower legs, and unexplained weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Abitate 250 mg Tablet should be avoided if you are allergic to it or any other components present in it. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention or taking any other medicines before taking Abitate 250 mg Tablet as it may cause serious side effects. Abitate 250 mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. This medicine is used in combination with prednisolone for the treatment of prostate cancer.

Drug-Drug Interactions

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AbirateroneMesoridazine
Critical
AbirateroneSaquinavir
Critical

Drug-Drug Interactions

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AbirateroneMesoridazine
Critical
How does the drug interact with Abitate 250 mg Tablet:
Taking Abitate 250 mg Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Abitate 250 mg Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Abitate 250 mg Tablet:
Taking Abitate 250 mg Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abitate 250 mg Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Abitate 250 mg Tablet:
Coadministration of Abitate 250 mg Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Abitate 250 mg Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Abitate 250 mg Tablet:
Taking Abitate 250 mg Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Abitate 250 mg Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Abitate 250 mg Tablet:
Taking Abitate 250 mg Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abitate 250 mg Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneQuinidine
Severe
How does the drug interact with Abitate 250 mg Tablet:
Taking Abitate 250 mg Tablet with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abitate 250 mg Tablet with Quinidine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneVemurafenib
Severe
How does the drug interact with Abitate 250 mg Tablet:
Taking Abitate 250 mg Tablet with Vemurafenib can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abitate 250 mg Tablet with Vemurafenib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Abitate 250 mg Tablet:
When taken in combination, Abitate 250 mg Tablet may considerably raise loperamide levels in the blood and cause irregular heart rhythm.

How to manage the interaction:
Although taking loperamide with Abitate 250 mg Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
AbirateroneBrexpiprazole
Severe
How does the drug interact with Abitate 250 mg Tablet:
Coadministration of Abitate 250 mg Tablet with Brexpiprazole can increase the levels of Brexpiprazole in the body. This increases the risk or severity of side effects like abnormal muscle movements or low blood pressure.

How to manage the interaction:
Taking Abitate 250 mg Tablet with Brexpiprazole together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience confusion, convulsions, muscle spasms, uncontrolled movements, dizziness, lightheadedness, fainting, and increased pulse or heart rate, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneDroperidol
Severe
How does the drug interact with Abitate 250 mg Tablet:
Using Droperidol together with Abitate 250 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Abitate 250 mg Tablet and Droperidol together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: an irregular heart rhythm, a heart condition, problems with your heart's electrical system, severe or long-lasting diarrhea or vomiting, complications, sudden dizziness or lightheadedness, fainting, difficulty breathing, heart palpitations, weakness, feeling sleepy or confused, muscle pain, or feeling nauseous or vomiting. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
  • It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
  • Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
  • Maintain a healthy weight by doing regular simple exercises and yoga. 
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
  • Avoid including red meat high amounts of meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

All Substitutes & Brand Comparisons

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Alcohol

Caution

Interaction of Abitate 250 mg Tablet with alcohol is unknown. It is advisable to consult your doctor if you have concerns.

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Pregnancy

Not applicable

Not intended for women.

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Breast Feeding

Not applicable

Not intended for women.

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Driving

Caution

Abitate 250 mg Tablet may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery while taking Abitate 250 mg Tablet until your vision improves.

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Liver

Caution

Abitate 250 mg Tablet should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Abitate 250 mg Tablet should be used with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose based on your condition.

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Children

Unsafe

Abitate 250 mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established.

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Heart

Abitate 250 mg Tablet may be used in heart patients, but it can cause high blood pressure, fluid retention, and low potassium, which may worsen cardiac conditions. Careful monitoring and management of heart function and electrolytes are essential during treatment.

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Geriatrics

Caution

Geriatric patients can take Abitate 250 mg Tablet , but it may be more prone to high blood pressure, low potassium, and fluid retention. Regular monitoring and dose adjustments are essential to ensure safe and effective treatment.

FAQs

Abitate 250 mg Tablet is used to treat Prostate Cancer.

Abitate 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

No, do not stop taking Abitate 250 mg Tablet without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.

The common side-effects of Abitate 250 mg Tablet are nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain. These side effects usually do not require any medical attention.

Take Abitate 250 mg Tablet as advised by your doctor. However, if you forget or miss any dose of Abitate 250 mg Tablet , take it as soon as you remember unless it is time for your next dose. But do not double the dose.

Inform your doctor if you have a pre-existing or a history of liver/kidney disease, hypoglycemia, hypokalemia, bone disorders, adrenocortical insufficiency, fluid retention and cardiovascular conditions before taking Abitate 250 mg Tablet .

Abitate 250 mg Tablet is not a cure for prostate cancer. However, it helps manage advanced stages by blocking testosterone production, thereby slowing the growth and progression of the cancer.

No, Abitate 250 mg Tablet is not a chemotherapy drug. Abitate 250 mg Tablet is a hormonal therapy that lowers testosterone levels to reduce the growth of prostate cancer.

You need to take prednisolone with Abitate 250 mg Tablet to reduce the risk of high blood pressure, fluid retention (too much water in your body), and low potassium levels in your blood which may be caused by Abitate 250 mg Tablet .

Yes, Abitate 250 mg Tablet can affect the liver. Your healthcare provider will perform blood tests to check your liver function before and during treatment.

Liver function tests (investigation) should be conducted before starting Abitate 250 mg Tablet and periodically during treatment, as advised by your healthcare provider.

Abitate 250 mg Tablet should be taken once daily on an empty stomach, at least two hours after eating or one hour before eating. Swallow Abitate 250 mg Tablet whole with a glass of water; do not chew, crush, or break it. Always follow the recommended dose.

Country of origin

India

Manufacturer/Marketer address

463, 4 Th Floor, Rpg House, Dr. Annie Besant Road, Worli, Mumbai €“ 400 030. Maharashtra, India
Other Info - ABI0052

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