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compositionComposition:BICALUTAMIDE-50MG
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Ablu-50 mg Tablet 10's is used to treat prostate cancer. It contains Bicalutamide, which prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor. It may cause side effects such as weakness, skin rash, swelling and tenderness of the breast, nausea, dry skin, weight gain, hair loss, hot flushes (sudden feeling of warmth), anemia (lack of blood), reduces sex drive, constipation, depression, indigestion or dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

BICALUTAMIDE-50MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Ablu-50 mg Tablet 10's

Ablu-50 mg Tablet 10's is an oral medicine primarily used to treat advanced prostate cancer. Its main medical purpose is to slow down or halt the growth of cancer cells by blocking the male hormones that fuel them. This treatment is typically prescribed in combination with an LHRH agonist (combined androgen blockade) or following surgical removal of the testes (orchiectomy) to improve treatment effectiveness.

You should take this medicine once daily, maintaining consistency by taking it at the exact same time each day. It can be taken either with or without food, depending on your preference. Combining this treatment with a heart-healthy diet and regular, mild exercise can help improve your overall energy levels and therapy results.

While taking Ablu-50 mg Tablet 10's, you may experience some common side effects such as hot flashes, breast tenderness, or feeling unusually tired. However, you must contact your doctor immediately if you experience serious symptoms like severe abdominal pain, dark urine, or yellowing of your skin and eyes, which may point to liver damage.

Before starting your treatment, tell your doctor if you have a history of liver problems, heart disease, or diabetes. Do not take this if you are a woman, a child, or if you are pregnant, as the active drug can cause severe harm to an unborn baby.

This medicine can interact with other treatments, such as blood thinners, which can increase your risk of bleeding, and drinking alcohol may put extra strain on your liver. Elderly patients should consult their healthcare provider to ensure this treatment is safe for their specific health needs.

Uses of Ablu-50 mg Tablet 10's

Ablu-50 mg Tablet 10's used in the treatment of Prostate cancer. The detailed uses of Ablu-50 mg Tablet 10's are as follows:

  • Prostate cancer: Ablu-50 mg Tablet 10's is prescribed to treat advanced prostate cancer, helping to manage the condition by blocking the hormones that cause cancer cells to multiply and spread.

Key Benefits

Ablu-50 mg Tablet 10's helps manage prostate cancer by slowing the growth and spread of cancer cells when used as part of your treatment plan. It also supports long-term disease control and helps improve your overall quality of life.

Benefits may include:

  • Helps slow the growth and progression of prostate cancer.
  • Reduces symptoms such as urinary difficulties and cancer-related bone pain.
  • Supports the effectiveness of other prostate cancer treatments.
  • Promotes better long-term disease management.
  • Improves overall quality of life by helping control cancer-related symptoms.​
Side effects of Ablu-50 mg Tablet
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Staying hydrated helps prevent hematuria by increasing urine production. You should drink about eight glasses of fluid per day, and more in hot weather.
  • Avoiding smoking as it is linked to urinary tract cancers.
  • Eat berries like Cranberries, blueberries, and raspberries can help promote urinary tract health and protect against infection.
  • Taking Vitamin C can help treat urinary tract infections.
  • Avoid irritants that can contribute to hematuria.
  • Empty the bladder regularly, as it can helps in preventing hematuria.

Directions for Use

  • To ensure the medicine works correctly, swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can affect how the medicine is absorbed into your body.
  • You can take this tablet with or without food, but it is best to establish a routine by taking it at the exact same time every day.
  • Always follow your doctor's exact instructions regarding how to take this medicine. Do not change your dose or stop taking it without consulting your healthcare provider first.

How Ablu-50 mg Tablet 10's Works

Ablu-50 mg Tablet 10's contains Bicalutamide, which belongs to a class of medicines known as antiandrogens. Prostate cancer cells often rely on male hormones, like testosterone, to grow and divide. This medicine works by attaching itself to the docking ports (receptors) on the cancer cells, effectively locking out these male hormones. By blocking this biological pathway, the medicine starves the cancer cells of the signals they need to multiply. These actions help to shrink the tumour or slow down its growth over time.
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Alcohol

Caution

Interaction of Ablu-50 mg Tablet 10's with alcohol is unknown. Please consult a doctor before consuming alcohol while using Ablu-50 mg Tablet 10's.

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Pregnancy

Unsafe

Ablu-50 mg Tablet 10's is contraindicated in pregnant women as it is not approved for use in women. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Ablu-50 mg Tablet 10's is contraindicated in breastfeeding women as it is not approved for use in women. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Ablu-50 mg Tablet 10's may cause drowsiness in some people. Therefore, avoid driving if you are drowsy after taking Ablu-50 mg Tablet 10's.

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Liver

Caution

Take Ablu-50 mg Tablet 10's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

Ablu-50 mg Tablet 10's is safe to use in patients with kidney problems if prescribed by a doctor.

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Children

Unsafe

Ablu-50 mg Tablet 10's is not recommended for children as the safety and effectiveness were not established.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects.

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Geriatrics

Safe if prescribed

Ablu-50 mg Tablet 10's can be safely given in elderly patients if recommended by the physician.

What if I have taken an overdose of Ablu-50 mg Tablet 10's

If you suspect an overdose or if someone else accidentally takes this medication, seek immediate emergency medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Eat a heart-healthy diet: Focus on nutrient-rich foods like vegetables, fruits, lean proteins, and whole grains to support your cardiovascular system during hormone therapy.
  • Stay active: Engage in regular, light-to-moderate physical exercise, such as walking or swimming, to help fight fatigue and maintain muscle strength.
  • Limit alcohol consumption: Avoid or minimise drinking alcohol to prevent putting extra stress on your liver while it processes this medication.
  • Monitor your blood sugar: If you have diabetes, check your blood sugar levels regularly, as hormone treatments can sometimes affect blood glucose control.
  • Support your bone health: If you are receiving long-term hormone therapy, your doctor may recommend calcium and vitamin D supplements, weight-bearing exercise, and, in some cases, bone density (DEXA) scans to help reduce the risk of bone loss and osteoporosis.
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Have a query?

How Soon It Starts Working

  • The time required for Ablu-50 mg Tablet 10's to start to work: The time required for Ablu-50 mg Tablet 10's to show its action is not clinically established.
  • The time for which the effects of Ablu-50 mg Tablet 10's last: The duration of action for Ablu-50 mg Tablet 10's is not clinically established.

What if you forget to take Ablu-50 mg Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Be careful when driving: Avoid driving or operating machinery if you feel dizzy, sleepy, or have blurred vision after taking this medicine.
  • Attend regular check-ups: Keep all your scheduled doctor appointments. Regular blood tests, including liver function and PSA tests, help your doctor monitor your health and check how well the treatment is working.
  • Protect your skin from sunlight: Wear protective clothing and apply a high-SPF sunscreen when outdoors. This medicine can make your skin more sensitive to sunlight and increase the risk of sunburn.
  • Handle broken tablets safely: This medicine is not for use in women. If a pregnant woman or someone who may become pregnant needs to handle broken or crushed tablets, they should wear gloves or avoid direct contact to protect the unborn baby.
  • Use effective birth control: Use reliable contraception, such as condoms, during sexual activity with a partner who can become pregnant. Continue using birth control for the period recommended by your doctor after stopping treatment.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (e.g., warfarin): Taking these medicines with Ablu-50 mg Tablet 10's can increase your risk of severe bleeding. Your doctor may need to adjust your blood thinner dose.
  • Heart rhythm medications (e.g., amiodarone, sotalol): Combining Ablu-50 mg Tablet 10's with these drugs can increase the risk of irregular heartbeats.
BicalutamideZiprasidone
Critical
BicalutamideDronedarone
Critical

Drug-Drug Interactions

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BicalutamideZiprasidone
Critical
How does the drug interact with Ablu-50 mg Tablet:
Taking Ablu-50 mg Tablet and Ziprasidone can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Ablu-50 mg Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
BicalutamideDronedarone
Critical
How does the drug interact with Ablu-50 mg Tablet:
When Ablu-50 mg Tablet is taken with Dronedarone, can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ablu-50 mg Tablet with Dronedarone is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideMesoridazine
Critical
How does the drug interact with Ablu-50 mg Tablet:
Taking Ablu-50 mg Tablet with Mesoridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ablu-50 mg Tablet with Mesoridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideHalofantrine
Critical
How does the drug interact with Ablu-50 mg Tablet:
Taking Ablu-50 mg Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ablu-50 mg Tablet with Halofantrine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideSaquinavir
Critical
How does the drug interact with Ablu-50 mg Tablet:
When Ablu-50 mg Tablet is taken with Saquinavir, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ablu-50 mg Tablet with Saquinavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideThioridazine
Critical
How does the drug interact with Ablu-50 mg Tablet:
Taking Ablu-50 mg Tablet with Thioridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ablu-50 mg Tablet with Thioridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamidePimozide
Critical
How does the drug interact with Ablu-50 mg Tablet:
When Ablu-50 mg Tablet is taken with Pimozide, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ablu-50 mg Tablet with Pimozide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideLomitapide
Severe
How does the drug interact with Ablu-50 mg Tablet:
When Ablu-50 mg Tablet is taken with Lomitapide, it can increase the blood levels or effects of Lomitapide.

How to manage the interaction:
Although taking Ablu-50 mg Tablet and Lomitapide together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms like diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, dark colored urine, light-colored stools, and yellowing of the skin or eyes. consult a doctor. Do not discontinue any medications without a doctor's advice.
BicalutamideFingolimod
Severe
How does the drug interact with Ablu-50 mg Tablet:
Co-administration of Ablu-50 mg Tablet and Fingolimod together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ablu-50 mg Tablet and Fingolimod together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
BicalutamideAnagrelide
Severe
How does the drug interact with Ablu-50 mg Tablet:
Co-administration of Ablu-50 mg Tablet and Anagrelide together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ablu-50 mg Tablet and Anagrelide together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: May interfere with how your body processes Ablu-50 mg Tablet 10's, potentially increasing the risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Ablu-50 mg Tablet 10's is used to treat prostate cancer.
Ablu-50 mg Tablet 10's contains Bicalutamide, an anticancer drug that works by inhibiting the effects of androgens (male hormones) such as testosterone and reduces or prevents the growth of prostate cancer cells and eventually shrink the prostate tumour.
You are not recommended to take Ablu-50 mg Tablet 10's with anti-allergic drugs such as terfenadine or astemizole. It may increase the levels of terfenadine or astemizole in the blood and cause adverse effects, such as a severe irregular heartbeat. However, please consult a doctor before taking Ablu-50 mg Tablet 10's with other medicines.
Ablu-50 mg Tablet 10's may cause infertility or a period of subfertility (delay in conceiving) in men. Therefore, if you want to father a child, please discuss with your doctor before taking Ablu-50 mg Tablet 10's.
Ablu-50 mg Tablet 10's should be used with caution in diabetic patients as it may increase the risk of high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Ablu-50 mg Tablet 10's and inform your doctor if you have diabetes before taking Ablu-50 mg Tablet 10's.
Ablu-50 mg Tablet 10's is not recommended for patients suffering from heart rhythm problems such as arrhythmia (irregular heartbeat) as it may increase the risk of heart rhythm problems. Therefore, inform your doctor if you have any heart problems before taking Ablu-50 mg Tablet 10's.
Ablu-50 mg Tablet 10's increase skin sensitivity to the sun and make sunburn more easily. Therefore, avoid direct exposure to excessive UV-light or sunlight, wear protective clothing and use a sunscreen while going out in the sun.
While taking Ablu-50 mg Tablet 10's, avoid certain things to ensure your safety. Don't take other medicines like cisapride, astemizole, or terfenadine, as they may interact with Bicalutamide. Also, limit your sun exposure and wear protective clothing, as Bicalutamide may increase sunburn risk. If you're pregnant, breastfeeding, or planning to father a child, consult your doctor before taking Bicalutamide. Additionally, inform your doctor if you have diabetes, liver, or heart problems, as they may need to monitor you closely. By avoiding these things, you can use Bicalutamide safely and effectively.
Ablu-50 mg Tablet 10's is a medication used to treat prostate cancer, but it is not a traditional form of chemotherapy. Chemotherapy typically involves drugs that directly kill cancer cells. Ablu-50 mg Tablet 10's, on the other hand, is an anti-androgen medication that works by blocking the effects of male hormones (androgens) that fuel prostate cancer growth.
Yes, Ablu-50 mg Tablet 10's may cause hair loss as a side effect. Hair loss is a common side effect of bicalutamide. In most cases, it is mild to moderate, but in rare cases, it can be more severe.
Ablu-50 mg Tablet 10's is used to treat prostate cancer. Prostate cancer is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.
Take Ablu-50 mg Tablet 10's as directed by your healthcare provider, usually once a day, at the same time each day, to maintain consistent levels of the medication in your body. Swallow the tablet whole with water, with or without food. Don't chew or break the tablet. These steps will help you take your medication correctly and ensure it works effectively. If you have any questions, ask your healthcare provider for guidance.
Diarrhea is a possible side effect that may occur while using Ablu-50 mg Tablet 10's in some cases. It may vary from person to person. If it happens and persists, please consult your doctor and seek appropriate treatment. Do not take any antidiarrheal medications on your own.
The exact duration of taking Ablu-50 mg Tablet 10's will be determined by your doctor, based on your specific health needs and treatment goals. This medication is primarily used to treat prostate cancer, and the treatment period can vary significantly from person to person - ranging from several months to several years. To ensure the best possible outcome and effectively manage your condition, following your doctor's advice and taking the medication for the full recommended duration is essential. Don't stop taking the medication without consulting your doctor first, even if you start feeling better or experience side effects.
Common side effects of Ablu-50 mg Tablet 10's may include weakness, skin rash, swelling and tenderness of the breast, nausea, dry skin, weight gain, hair loss, hot flushes (sudden feeling of warmth), anaemia (lack of blood), reduced sex drive, constipation, depression, indigestion or dizziness. Most of these side effects of Ablu-50 mg Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Inform your doctor about all your medications, as some may interact with Ablu-50 mg Tablet 10's. Do not club any other medicines with Ablu-50 mg Tablet 10's unless prescribed by the doctor.
Ablu-50 mg Tablet 10's is not intended for use by women or children.
Seek immediate medical attention, as these may be symptoms of a serious lung problem.
Abdominal pain is the most common side effect of Ablu-50 mg Tablet 10's. It usually does not require medical care and resolves on its own over time. However, if it persists or worsens, contact your doctor.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Avoid consuming alcohol altogether while taking Ablu-50 mg Tablet 10's. Alcohol can increase the risk of liver problems, which is a serious side effect. To ensure your safety and well-being, it's best to abstain from alcohol completely during your treatment. Consult your doctor if you have any questions or concerns.
Breast swelling (gynecomastia) and tenderness are common side effects of Ablu-50 mg Tablet 10's. Let your doctor know if these symptoms become bothersome. Depending on your situation, your doctor may recommend pain-relieving measures, preventive or therapeutic breast radiotherapy, or medicines such as tamoxifen to help reduce breast pain and enlargement. Do not start any treatment without medical advice.
Yes, this medicine can affect liver function in some patients. Your doctor will perform regular blood tests to check your liver health while you are on this medication. Talk to your doctor immediately if you notice yellowing of your skin or eyes.
Yes, feeling unusually tired or weak is a common side effect of hormone therapy. Regular, light exercise and getting plenty of rest can help manage this fatigue. Talk to your doctor if the weakness is severe or worsens over time.
Your doctor will regularly monitor your progress using prostate-specific antigen (PSA) blood tests, liver function tests, and clinical assessments to evaluate how well your cancer is responding to treatment and to detect any side effects early. The frequency of these tests depends on your individual treatment plan.

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Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - ABL0011
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