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  3. Acemiz Rab Tablet 10's

Acemiz Rab Tablet 10's, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Acemiz Rab Tablet is used to reduce and relieve pain and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It may also be indicated in the treatment of pain associated with post-traumatic and post-operative cases. It contains Aceclofenac and Rabeprazole, which works by reducing the production of prostaglandins (chemicals) that cause pain and inflammation. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, which reduces the amount of acid the stomach makes, thus preventing damage to the stomach. Thus, it helps reduce pain with minimal gastric irritation caused due to Aceclofenac alone. In some cases, you may experience side effects such as indigestion, stomach pain, constipation, dizziness, nausea and diarrhoea.
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Composition :

ACECLOFENAC-200MG + RABEPRAZOLE-20MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Acemiz Rab Tablet

Acemiz Rab Tablet is used to reduce and relieve pain and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Acemiz Rab Tablet may also be indicated in the treatment of pain associated with post-traumatic and post-operative cases.

Acemiz Rab Tablet combines two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine belonging to a group of proton pump inhibitors that reduce the amount of acid the stomach makes, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused by Aceclofenac alone.

Take Acemiz Rab Tablet as prescribed by your doctor. You are advised to take Acemiz Rab Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience indigestion, stomach pain, constipation, dizziness, nausea and diarrhoea. Most of these side effects of Acemiz Rab Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking the Acemiz Rab Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Inform your doctor if you are suffering from kidney, liver, or heart disease. Acemiz Rab Tablet may cause dizziness, so avoid driving or operating machinery unless you are alert. Acemiz Rab Tablet is not recommended for use during pregnancy, breastfeeding, or in children. Avoid consuming alcohol along with Acemiz Rab Tablet as it could lead to increased dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Acemiz Rab Tablet

Treatment of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis.

Directions for Use

• Take Acemiz Rab Tablet with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Acemiz Rab Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Acemiz Rab Tablet is a combination of two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac belongs to the class of non-steroidal anti-inflammatory drugs (pain killers) that block the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). Prostaglandins play an important role in controlling pain and inflammation. By blocking the effect of COX enzymes, fewer PGs are produced. Thereby, it helps relieve pain and swelling associated with different types of arthritis, such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis (pain and stiffness in the backbone). On the other hand, Rabeprazole belongs to proton pump inhibitors (PPIs) that help reduce the excess amount of stomach acid and bile produced. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine that reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination is superior as it helps alleviate pain with minimal gastric irritation caused by Aceclofenac alone. Acemiz Rab Tablet is also used to relieve toothache and lower back, ear, and throat pain. 

How Acemiz Rab Tablet Works

Acemiz Rab Tablet combines two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine belonging to a group of proton pump inhibitors that reduce the amount of acid the stomach makes, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused by Aceclofenac alone.

Storage

Keep Acemiz Rab Tablet out of the sight and reach of children.
Side effects of Acemiz Rab Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Do not consume spicy foods, caffeine, and alcohol.
  • Choose low-acid fruits and vegetables like apples, melons, and carrots.
  • Include whole grains like whole-wheat bread, oatmeal, and brown rice.
  • Limit processed meats like hotdogs and sausages.
  • Avoid fatty, spicy, or acidic salad dressings.
  • Limit tomatoes and tomato-based products.
  • Quit smoking to promote ulcer healing.
  • Adopt a balanced diet and lifestyle to reduce the risk of peptic ulcers.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Acemiz Rab Tablet

Do not take more than the prescribed dose of Acemiz Rab Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Acemiz Rab Tablet if you are allergic to Acemiz Rab Tablet , have severe heart failure, suffered bleeding problems (such as bleeding from the stomach or bowels while taking any pain killers) or liver or kidney problems, have suffered bleeding problems and clotting problems. Inform your doctor before taking Acemiz Rab Tablet if you have or had disorders of the stomach, blood circulation problems to the brain, asthma, porphyria (a disorder in the formation of red blood pigment), diabetes, high blood pressure, systemic lupus erythematosus (an autoimmune condition that causes joint pain, fever and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss); if you are recovering from major surgery or if you are elderly. Do not take Acemiz Rab Tablet if you are pregnant or breastfeeding unless prescribed. Acemiz Rab Tablet contains Aceclofenac which should not be used during the last three months of pregnancy. Acemiz Rab Tablet may be excreted in breastmilk. Therefore, avoid breastfeeding and consult a doctor. Acemiz Rab Tablet should not be given to children as safety has not been established. Acemiz Rab Tablet can cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol with Acemiz Rab Tablet as it could lead to increased drowsiness and increase the risk of stomach bleeding. Do not take other NSAIDs for pain relief or Acemiz Rab Tablet unless prescribed. Prolonged intake of PPIs or proton pump inhibitors like Rabeprazole may cause brittle bones so intake of Vitamin D and calcium can be additionally given by your doctor while using Acemiz Rab Tablet . 

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
How does the drug interact with Acemiz Rab Tablet:
When used in combination with erlotinib, Acemiz Rab Tablet may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Acemiz Rab Tablet with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleRilpivirine
Critical
How does the drug interact with Acemiz Rab Tablet:
Co-administration of Acemiz Rab Tablet can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Acemiz Rab Tablet with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
RabeprazoleDasatinib
Severe
How does the drug interact with Acemiz Rab Tablet:
Taking Acemiz Rab Tablet together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking Acemiz Rab Tablet and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazolePazopanib
Severe
How does the drug interact with Acemiz Rab Tablet:
Taking Acemiz Rab Tablet together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking Acemiz Rab Tablet and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
RabeprazoleClopidogrel
Severe
How does the drug interact with Acemiz Rab Tablet:
Taking Clopidogrel with Acemiz Rab Tablet can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and Acemiz Rab Tablet together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
RabeprazoleGefitinib
Severe
How does the drug interact with Acemiz Rab Tablet:
Taking Acemiz Rab Tablet together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking Acemiz Rab Tablet and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after Acemiz Rab Tablet. Do not discontinue any medications without a doctor's advice.
RabeprazolePhenytoin
Severe
How does the drug interact with Acemiz Rab Tablet:
When Phenytoin and Acemiz Rab Tablet are taken in combination, Phenytoin will reduce the concentration or impact of Acemiz Rab Tablet.

How to manage the interaction:
Although taking Phenytoin and Acemiz Rab Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleMethotrexate
Severe
How does the drug interact with Acemiz Rab Tablet:
Co-administration of Methotrexate with Acemiz Rab Tablet can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Acemiz Rab Tablet and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
RabeprazoleAtazanavir
Severe
How does the drug interact with Acemiz Rab Tablet:
Co-administration of Atazanavir's blood levels and absorption can both be affected by Acemiz Rab Tablet, which decreases the atazanavir's ability to treat HIV.

How to manage the interaction:
Although taking Acemiz Rab Tablet and atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleAcalabrutinib
Severe
How does the drug interact with Acemiz Rab Tablet:
Taking Acemiz Rab Tablet together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking Acemiz Rab Tablet and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Foods containing flavonoids such as soy, berries, broccoli, grapes and green tea help in reducing inflammation.

  • Include high fibre-containing foods, berries, cherries, leafy green veggies, and black peppers in your meal. These foods are full of antioxidants, calcium, and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics that help in the prevention of excess stomach acid production.

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Acemiz Rab Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Acemiz Rab Tablet . Alcohol intake along Acemiz Rab Tablet may cause increased drowsiness and drowsiness. It may also increase the risk of stomach bleeding. Please consult your doctor if you have any concerns regarding this.

bannner image

Pregnancy

Unsafe

Acemiz Rab Tablet is a Category C pregnancy drug and is not recommended for pregnant women, especially in the third trimester as it may cause adverse effects in the baby. However, please consult a doctor if you are pregnant or planning for pregnancy before taking Acemiz Rab Tablet .

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking Acemiz Rab Tablet as it may be excreted in breast milk and cause adverse effects in the baby. Please consult a doctor if you are breastfeeding.

bannner image

Driving

Caution

Acemiz Rab Tablet may cause drowsiness, dizziness, or abnormal vision. Do not drive or operate heavy machinery if you feel dizzy or drowsy.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with severe liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Take Acemiz Rab Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Acemiz Rab Tablet if you have severe kidney disease.

bannner image

Children

Unsafe

Acemiz Rab Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

Have a query?

FAQs

Acemiz Rab Tablet is used to reduce and relieve pain and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It may also be indicated in the treatment of pain associated with post-traumatic and post-operative cases.

Acemiz Rab Tablet contains Aceclofenac and Rabeprazole. Aceclofenac is a pain killer called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) which works by blocking the effect of chemical messengers (prostaglandin), thereby helping in reducing pain, and inflammation. Rabeprazole works by blocking the action of an enzyme called a proton pump, which is responsible for the production of stomach acid. Thus, the combination used for pain relief, decrease stiffness in joints and reduces the release of excess stomach acid caused by aceclofenac.

Acemiz Rab Tablet is not recommended for asthma patients as it may worsen the condition. Therefore, please inform your doctor if you have asthma or a history of asthma due to the use of aspirin or any other non-steroidal drugs.

You are not recommended to take Acemiz Rab Tablet with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

Aceclofenac in Acemiz Rab Tablet may increase the risk of heart problems such as heart attack, especially when used in high doses or for prolonged duration and in patients who are smokers, have high blood pressure, diabetes or high cholesterol. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Acemiz Rab Tablet . However, taking Acemiz Rab Tablet in the dose and for the duration, as prescribed by your doctor, is recommended.

Acemiz Rab Tablet may impair fertility in females and make it more difficult to conceive. Therefore, if you are pregnant, planning for pregnancy or have difficulties conceiving, please consult your doctor before taking Acemiz Rab Tablet .

Do not take Acemiz Rab Tablet for longer durations as it might increase the risk of heart problems, stomach bleeding and might increase the risk of fractures of the hip, spine, and wrist. Do not exceed the dose and duration of treatment as prescribed by the doctor.

Acemiz Rab Tablet is a combination medicine containing Aceclofenac (painkiller) and Rabeprazole (antacid). It is used to treat osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Do not discontinue Acemiz Rab Tablet without consulting your doctor. To treat your condition effectively, keep taking Acemiz Rab Tablet for the prescribed duration.

Nausea and vomiting could be side effects of Acemiz Rab Tablet . Drink enough fluids by taking frequent sips and eat small, frequent meals. If the condition persists or worsens, consult the doctor.

Store Acemiz Rab Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.

Acemiz Rab Tablet may cause side effects like indigestion, stomach pain, constipation, dizziness, nausea and diarrhoea. Most of these side effects of Acemiz Rab Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Acemiz Rab Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol with Acemiz Rab Tablet as it could lead to increased drowsiness.

Acemiz Rab Tablet can be taken with vitamin B-complex if advised by the doctor. Talk to the doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - ACE0499

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:35 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/4240/pil#gref
  2. https://www.drugs.com/mtm/rabeprazole.html
  3. https://www.nhs.uk/medicines/rabeprazole/
  4. https://www.zoylo.com/medicines/rabeprazole-20-mg-aceclofenac-200-mg-tablet

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