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  3. Acerest-Plus Oral Suspension

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Acerest-Plus Oral Suspension, Pack of 1 Suspension
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Acerest-Plus Oral Suspension is used to reduce pain and inflammation. It helps in relieving pain from conditions like headaches, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It contains Aceclofenac and Paracetamol, which work by blocking the chemical messengers responsible for causing pain, inflammation, and fever. In some cases, it may cause side effects like dizziness, nausea, digestion problems (constipation, flatulence, diarrhoea) and skin reactions (like rashes and hives). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ACECLOFENAC-50MG + PARACETAMOL-125MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Acerest-Plus Oral Suspension

Acerest-Plus Oral Suspension is used to reduce pain and inflammation. The pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Inflammation is a localized physical condition in which part of the body becomes reddened, swollen, hot and often painful.

Acerest-Plus Oral Suspension is composed of aceclofenac and paracetamol. Aceclofenac and Paracetamol both work by blocking the chemical messengers responsible for causing pain, inflammation, and fever.

Acerest-Plus Oral Suspension may cause side effects like dizziness, nausea, constipation, flatulence, diarrhoea, rashes and hives. Most of the side effects of Acerest-Plus Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Avoid taking Acerest-Plus Oral Suspension if you are allergic to any of the ingredients present in it. Taking more than the daily prescribed dose of Acerest-Plus Oral Suspension may cause liver damage or allergic reactions like swelling of the mouth, face, throat, difficulty in breathing, skin rash, itching, gastrointestinal bleeding and/or ulcer. 

Uses of Acerest-Plus Oral Suspension

Acerest-Plus Oral Suspension is used in the treatment of Pain, Inflammation, and fever. The detailed uses of Acerest-Plus Oral Suspension are as follows:

  • Pain Relief: Acerest-Plus Oral Suspension is used to relieve pain, by its analgesic effects, which block pain signals and reduce discomfort.
  • Inflammation: Acerest-Plus Oral Suspension helps to reduce inflammation and swelling associated with conditions like arthritis, osteoarthritis, and rheumatoid arthritis.
  • Fever Reduction: Acerest-Plus Oral Suspension is used to bring down elevated body temperature, providing relief from discomfort associated with fever.

Directions for Use

  • Acerest-Plus Oral Suspension can be taken with or without food, preferably with a meal.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Acerest-Plus Oral Suspension as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Acerest-Plus Oral Suspension helps to reduce pain and inflammation caused by various complications or conditions.
  • It significantly works on providing relief from pain for extended hours.
  • It contains paracetamol, which is less irritant to the stomach than other painkillers. Hence, it is well tolerated by patients who have an allergy to aspirin or a risk of gastrointestinal bleeding or ulcer formation.
  • Besides this, it does not affect bleeding time and also helps in reducing fever due to pain or swelling.

How Acerest-Plus Oral Suspension Works

Acerest-Plus Oral Suspension is composed of two medicines: Aceclofenac (pain reducer) and Paracetamol (fever reducer). Acerest-Plus Oral Suspension helps in relieving pain from conditions like headaches, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Aceclofenac and Paracetamol both work by blocking the chemical messengers responsible for causing pain, inflammation, and fever.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Acerest-Plus Oral Suspension

Do not take more than the prescribed dose of Acerest-Plus Oral Suspension as it may cause adverse effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Acerest-Plus Oral Suspension if you are allergic to it or its components.
  • Taking more than the daily prescribed dose of Acerest-Plus Oral Suspension may cause liver damage or allergic reactions like swelling of the mouth, face, throat, difficulty in breathing, skin rash or itching.
  • Most of the cases of liver injury are associated with the use of paracetamol. 
  • Gastrointestinal bleeding and ulcer formation are commonly observed with the use of Acerest-Plus Oral Suspension, so the doctor may prescribe you the lowest dose available.
  • Do not take Acerest-Plus Oral Suspension if you have asthma or allergies to painkillers, heart, kidney and liver conditions.
  • Acerest-Plus Oral Suspension should not be taken during pregnancy or by breastfeeding mothers as it may affect the baby.
  • The components of Acerest-Plus Oral Suspension can cause stomach upset. Thus, it is recommended to consume Acerest-Plus Oral Suspension with meals to minimize gastric side effects. If you have a diagnosis of peptic ulcer, Acerest-Plus Oral Suspension is best avoided unless prescribed by your doctor.
  • Although Acerest-Plus Oral Suspension provides symptomatic relief, it is strongly recommended to remain physically active as much as your condition allows.
  • Adopting a healthy lifestyle, coupled with a healthy diet containing high proteins, is the mainstay of the management of arthritic conditions.

Drug-Drug Interactions

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ParacetamolMipomersen
Severe
ParacetamolKetamine
Severe

Drug-Drug Interactions

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ParacetamolMipomersen
Severe
How does the drug interact with Acerest-Plus Oral Suspension:
Co-administration of Mipomersen with Acerest-Plus Oral Suspension may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Acerest-Plus Oral Suspension and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Acerest-Plus Oral Suspension:
Co-administration of ketamine and Acerest-Plus Oral Suspension may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Acerest-Plus Oral Suspension together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolValdecoxib
Severe
How does the drug interact with Acerest-Plus Oral Suspension:
Co-administration of Acerest-Plus Oral Suspension and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Acerest-Plus Oral Suspension and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Acerest-Plus Oral Suspension:
Co-administration of Acerest-Plus Oral Suspension and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Acerest-Plus Oral Suspension and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Acerest-Plus Oral Suspension:
Co-administration of Acerest-Plus Oral Suspension may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Acerest-Plus Oral Suspension, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Acerest-Plus Oral Suspension:
Co-administration of Acerest-Plus Oral Suspension and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Acerest-Plus Oral Suspension and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Acerest-Plus Oral Suspension:
Co-administration of Lomitapide and Acerest-Plus Oral Suspension may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Acerest-Plus Oral Suspension and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Acerest-Plus Oral Suspension:
Co-administration of Teriflunomide with Acerest-Plus Oral Suspension may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Acerest-Plus Oral Suspension with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AceclofenacAtenolol
Severe
How does the drug interact with Acerest-Plus Oral Suspension:
Co-administration of Atenolol with Acerest-Plus Oral Suspension could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Acerest-Plus Oral Suspension, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain and arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that have a minimum level of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Acerest-Plus Oral Suspension Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Acerest-Plus Oral Suspension as it contains paracetamol which can together damage your liver severely.

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Pregnancy

Consult your doctor

The safety of this medicine for use during pregnancy is not known. Hence, it is not recommended for use in pregnancy unless considered essential by your doctor.

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Breast Feeding

Consult your doctor

Acerest-Plus Oral Suspension should not be used without consultation with your doctor if you are breast-feeding. It is not known if this medicine passes into breast milk. It is not recommended for use during breast-feeding unless considered essential by your doctor.

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Driving

Unsafe

Acerest-Plus Oral Suspension usually causes dizziness, drowsiness and visual disturbances which may affect their ability to drive or operate machinery. Make sure you are not affected before driving or operating machinery.

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Liver

Caution

Acerest-Plus Oral Suspension to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Acerest-Plus Oral Suspension to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and efficacy of Acerest-Plus Oral Suspension in children have not been established. Acerest-Plus Oral Suspension is not recommended in children.

Have a query?

FAQs

Acerest-Plus Oral Suspension is used to reduce pain and inflammation.

No, Acerest-Plus Oral Suspension does not cure Rheumatoid arthritis but instead, it helps in reducing the pain and inflammation caused by it as it a pain killer.

Yes, Acerest-Plus Oral Suspension is may cause nausea or vomiting in some people. In order to avoid the same, you should take Acerest-Plus Oral Suspension with milk or food. In case you are still experiencing excessive nausea while consuming Acerest-Plus Oral Suspension, speak with your doctor right away.

No, do not suddenly stop taking Acerest-Plus Oral Suspension. If you want to stop taking this medicine, consult your doctor and he might gradually reduce the dose to avoid an unwanted increase in pain or inflammation.

No, Acerest-Plus Oral Suspension should ideally not be taken for stomach pain without consulting a physician. This medication can increase the secretion of stomach acid, which may worsen gastritis or an unknown underlying stomach ulcer.

Patients with mild to moderate renal impairment should be kept under surveillance. The lowest effective dose should be used and renal function monitored regularly. Effects on renal function are usually reversible on withdrawal of Acerest-Plus Oral Suspension.

Yes, let your doctor know if you are taking any other medicine for pain, arthritis or fever. If you experience dark stools, blood in vomit, or stomach pain, stop taking Acerest-Plus Oral Suspension and consult your doctor immediately, as these could be signs of bleeding in your stomach or intestine. Take Acerest-Plus Oral Suspension only for the duration as prescribed by your doctor. Do not take more than the prescribed dose, as it may cause an overdose.

Acerest-Plus Oral Suspension already contains Paracetamol and Aceclofenac. So, avoid taking additional paracetamol. If your pain does not subside, consult your doctor so that they may increase the dose or add another medicine depending on your condition.

Yes, Acerest-Plus Oral Suspension is a painkiller. It contains Aceclofenac and Paracetamol, which helps to relieve pain.

You are recommended to consult your doctor before taking Acerest-Plus Oral Suspension with antibiotics to avoid drug interactions.

Acerest-Plus Oral Suspension is safe if used as advised by the doctor. Follow your doctor’s instructions.

Yes, the use of Acerest-Plus Oral Suspension can cause dizziness (feeling faint, lightheaded, unsteady, or weak) in some patients. If you feel dizzy or lightheaded, take rest for sometime and resume once you feel better.

Acerest-Plus Oral Suspension is contraindicated in patients with known allergy to any of its ingredients or in patients or other painkillers (NSAIDs). Patients with a history of stomach ulcers or active, recurrent stomach ulcer/bleeding should ideally avoid taking Acerest-Plus Oral Suspension. Additionally, patients with a history of high blood pressure, heart failure, and kidney or liver disease, should also avoid taking Acerest-Plus Oral Suspension.

Yes, Acerest-Plus Oral Suspension be taken with vitamin B-complex as it helps to treat vitamin deficiency that may be the cause of underlying pain. However, please consult your doctor before using Acerest-Plus Oral Suspension with other medicines or supplements.

No, taking higher dose of Acerest-Plus Oral Suspension than recommended may cause serious liver damage or allergic reactions such as swelling of the mouth, face and throat; itching; rash or difficulty in breathing. If the pain is not relieved or if you are experience increased severity of pain by the recommended doses, please consult your doctor.

Store Acerest-Plus Oral Suspension at room temperature in a dry place. Protect from sunlight. Keep it out of reach of children.

Acerest-Plus Oral Suspension may take about 1.5 to 3 hours after oral administration to show its effect. However, the time may vary with every individual patient to get the desired results.

The dosage of Acerest-Plus Oral Suspension will be decided by your doctor. Follow doctor’s instructions. Do not take more than the recommended dose.

No, you are not recommended to take Acerest-Plus Oral Suspension along with other painkiller tablets as it may cause unwanted side effects such as stomach ulcers or pain. Therefore, please consult your doctor before taking Acerest-Plus Oral Suspension with other medicines.

Acerest-Plus Oral Suspension is not recommended for children as the safety and efficacy have not been established.

Acerest-Plus Oral Suspension contains Aceclofenac (pain reducer) and Paracetamol (fever reducer) which work by blocking the chemical messengers responsible for causing pain, inflammation, and fever.

Take Acerest-Plus Oral Suspension as advised by your doctor. Swallow it as whole with a glass of water. Do not crush, chew or break it.

Acerest-Plus Oral Suspension may cause side effects such as nausea, dizziness, diarrhoea, flatulence, or constipation. If these side effects persist or worsen, please consult your doctor.

You are preferably advised to take Acerest-Plus Oral Suspension after meals, as food helps to prevent any potential gastric irritation the drug might cause when taken on an empty stomach. Follow doctor’s instructions.

If you forget to take a dose of Acerest-Plus Oral Suspension, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.

You are recommended to consult your doctor before taking other medicines with Acerest-Plus Oral Suspension to avoid drug interactions.

Country of origin

India
Other Info - AC83987

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 18, 2025 | 1:05 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.4240.pdf
  2. https://www.medicines.org.uk/emc/files/pil.10548.pdf
  3. https://www.ciplamed.com/content/voltanec-pr-tablets
  4. https://www.medicineindia.org/pharmacology-for-generic/177/aceclofenac-paracetamol
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