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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Aceret 25 Capsule is used to treat psoriasis. It contains Acitretin, which slows down the progression of the disease. It reduces the speed of skin cell growth and gradually clears the affected skin. It helps reduce the redness, scaling, and thickness of psoriasis rashes. It may cause side effects such as dry lips, peeling of the skin, scaling and thinning of healthy skin, reddening of the skin, itching and burning sensation on the skin.
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Composition :

ACITRETIN-25MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Aceret 25 Capsule

Aceret 25 Capsule is used to treat psoriasis. Psoriasis is an autoimmune (immune system attacks healthy cells) skin disorder in which the skin becomes scaly, swollen, and itchy. It mostly affects the knee, elbows, scalp, and trunk. It is a lifelong condition, and treatment is given to remove affected skin cells and avoid flare-ups of the disease.

Aceret 25 Capsule contains ‘Acitretin’, which belongs to the class of retinoids derived from vitamin A. It has anti-inflammatory and antiproliferative (decreases skin cell multiplication) properties. It works by slowing down the progression of the disease. It reduces the speed of skin cell growth and gradually clears the affected skin. It helps reduce the redness, scaling, and thickness of psoriasis rashes.

Aceret 25 Capsule may cause side-effects such as dry lips, peeling of the skin, especially the palms of the hands and soles of the feet, nose bleed, scaling and thinning of healthy skin, reddening of the skin, itching, burning sensation on the skin, sticky skin, hair loss, swelling and pain in the area around your nails, fragile nails, inflammation of the eye (conjunctivitis), increased thirst, and feeling cold. These side effects usually go away after discontinuing the treatment. However, if any of these side effects persist or worsen, inform your doctor immediately.

Do not take Aceret 25 Capsule if you are allergic to Acitretin or any other ingredients present in it. Aceret 25 Capsule should not be used in patients with liver or kidney failure or high cholesterol and who are taking other medicines containing retinoids or supplements containing vitamin A. Aceret 25 Capsule should not be used in pregnant and breastfeeding women. Aceret 25 Capsule should be used with caution in children as it may affect growth and bone development. Aceret 25 Capsule may require dose adjustments when used in older people. Do not take alcohol, as it may increase the risk of side effects. Aceret 25 Capsule may cause vision problems, especially in the dark, so do not drive or operate heavy machinery if you notice any vision problems.

Uses of Aceret 25 Capsule

Treatment of Psoriasis

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Aceret 25 Capsule contains ‘Acitretin’, which belongs to the class ‘retinoids’. Retinoids are derived from vitamin A (retinol) and have anti-inflammatory and antiproliferative (reduces rapid skin cell division) action. Aceret 25 Capsule works by slowing down the progression of the diseases. Aceret 25 Capsule is used when the skin condition doesn’t improve with other conventional therapies. It can treat severe or extensive skin problems where the skin has become thick and scaly, such as psoriasis. It can be long-term maintenance therapy for psoriasis patients. It can also be used in the treatment of other skin conditions such as ichthyosis (genetic skin disorder), pityriasis (skin rashes that appear as large spots on the chest, abdomen, or back), and lichen planus (itchy, non-infectious rashes on arms and legs).

How Aceret 25 Capsule Works

Aceret 25 Capsule contains ‘Acitretin’, which belongs to the class of retinoids derived from vitamin A. It has anti-inflammatory and antiproliferative (decreases skin cell multiplication) properties. It works by slowing down the progression of the disease. It reduces the speed of skin cell growth and gradually clears the affected skin.

Storage

Store in a cool and dry place away from sunlight
Side effects of Aceret 25 Capsule
  • Moisturize your nails with oil or lotion.
  • Cover your nails with gloves while cleaning utensils or other objects.
  • Maintain short, clean nails with gentle care.
  • Avoid damaging your nails by picking or biting.
  • Limit using nail polish and choose a gentle remover.
  • Wash hands with mild cleaner and warm water.
  • Refrain from using strong chemicals that can dry out your nails.
  • Wear long sleeves and pants to protect your fragile skin, especially when doing things like gardening or working outside.
  • Limit exposure to the sun, and when going outdoors, use sunscreen to avoid damaging your skin.
  • Keep your skin hydrated and protected by using moisturizing creams.
  • Use soft padding to cover sharp edges on furniture to prevent injuries.
  • Stop taking any medication that causes skin thinning, and if frequent skin tears occur, consult a doctor or dermatologist for further advice.
  • Consider taking protein and collagen supplements with your doctor's approval to slow skin thinning.
  • You can also take vitamin supplements, like A, B complex, C, D, and E, along with minerals like iron, zinc, biotin, selenium, and chromium, to improve your skin health.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.

What if I have taken an overdose of Aceret 25 Capsule

Do not take more than the prescribed dose of Aceret 25 Capsule as it may cause overdose. The symptoms of overdose include headache, nausea, vomiting, drowsiness, itching and irritability. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Aceret 25 Capsule should not be used in pregnant and breastfeeding women. So, the doctor may advise you to take a pregnancy test before using Aceret 25 Capsule . You should also take effective and reliable contraception (such as an intrauterine device, contraceptive implant, or contraceptive pill and condom) during the treatment and after three years of discontinuing the treatment. You should take reliable contraception even if your periods are not regular or not sexually active unless your doctor decides that this is unnecessary. You should not donate blood during the treatment and after three years of discontinuing the treatment. Aceret 25 Capsule should be used in caution in patients with diabetes as it can alter blood glucose levels. Aceret 25 Capsule may cause vision problems, especially in the night-time. So, inform your doctor if you notice vision problems. Do not wear contact lenses during the treatment as the Aceret 25 Capsule may cause dry eyes. Aceret 25 Capsule may increase skin sensitivity, so avoid going in strong sunlight and using a sunbed. Aceret 25 Capsule may affect your mood, so inform your doctor if you have mental health problems like depression. Also, inform your doctor if you notice drastic mood changes while using Aceret 25 Capsule .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Aceret 25 Capsule:
Coadministration of Aceret 25 Capsule with Doxycycline can increase the risk and severity of vision problems.

How to manage the interaction:
Taking Aceret 25 Capsule with Doxycycline together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aceret 25 Capsule:
Coadministration of Aceret 25 Capsule with Levonorgestrel can increase the risk and severity of birth defects in unborn when taken by a pregnant woman.

How to manage the interaction:
Taking Aceret 25 Capsule with Levonorgestrel together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Never use Aceret 25 Capsule if you are pregnant. Do not stop using any medications without talking to a doctor.
AcitretinEtonogestrel
Critical
How does the drug interact with Aceret 25 Capsule:
Coadministration of Aceret 25 Capsule with Etonogestrel can increase the risk and severity of birth defects when taken in pregnant women.

How to manage the interaction:
Taking Aceret 25 Capsule with Etonogestrel together is generally avoided as it can result in an interaction which can be serious, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aceret 25 Capsule:
Coadministration of Aceret 25 Capsule with Tetracycline can increase the risk and severity of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Aceret 25 Capsule with Tetracycline together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aceret 25 Capsule:
Co-administration of Aceret 25 Capsule with Oxytetracycline can increase the risk of a rare and serious condition called pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Aceret 25 Capsule with Oxytetracycline together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aceret 25 Capsule:
Coadministration of Aceret 25 Capsule with Medroxyprogesterone can increase the risk and severity of birth defects when taken by a pregnant woman.

How to manage the interaction:
Taking Aceret 25 Capsule with Medroxyprogesterone together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aceret 25 Capsule:
Co-administration of Aceret 25 Capsule with Minocycline may increase the risk of a serious condition called pseudomotor cerebral (false brain tumour).

How to manage the interaction:
There's a possible interaction between Aceret 25 Capsule and Minocycline should be used together only if prescribed by a doctor. However, if you develop symptoms such as nausea, vomiting, headache, or visual disturbances during treatment with either medication, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
AcitretinDemeclocycline
Critical
How does the drug interact with Aceret 25 Capsule:
Coadministration of Aceret 25 Capsule with Demeclocycline can increase the risk and severity of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Aceret 25 Capsule with Demeclocycline together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinEthanol
Critical
How does the drug interact with Aceret 25 Capsule:
Coadministration of Aceret 25 Capsule with Ethanol can increase the risk and severity of birth defects.

How to manage the interaction:
Taking Aceret 25 Capsule with Ethanol together is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinAminolevulinic acid
Severe
How does the drug interact with Aceret 25 Capsule:
Coadministration of Aminolevulinic acid with Aceret 25 Capsule may increase the risk of severe sunburn.

How to manage the interaction:
Although there is a possible interaction between Aminolevulinic acid and Acetretin, you can take these medicines together if prescribed by your doctor. Following treatment, you should limit or avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Use mild soap while taking baths and prefer warm baths.
  • Do not scratch or pick your skin to avoid infecting the affected area.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
  • Avoid consuming foods with excess sugar, as it may flare up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats, and fish in your diet.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics. 

Habit Forming

No

Therapeutic Class

RETINOIDS
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Alcohol

Unsafe

Aceret 25 Capsule may interact with alcohol and increase the risk of side-effects. So, it is not recommended to take alcohol, especially women of childbearing potential during the treatment and at least 2 months after completing the treatment.

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Pregnancy

Caution

Aceret 25 Capsule should not be used in pregnant women as it may cause harmful effects to the unborn baby or fetus. Consult your doctor for further advice.

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Breast Feeding

Caution

Aceret 25 Capsule should not be given to breastfeeding mothers as it may pass into breast milk and harm the nursing baby. Consult your doctor for further advice.

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Driving

Unsafe

Aceret 25 Capsule may cause vision problems suddenly, especially in the dark. So, do not drive or operate heavy machinery if you notice any vision problems, especially at night.

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Liver

Caution

Aceret 25 Capsule should not be used in patients with severe liver failure as Aceret 25 Capsule may cause liver damage. In mild to moderate liver diseases, the dose may have to be adjusted by your doctor.

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Kidney

Caution

Aceret 25 Capsule should not be used in patients with severe kidney failure. In mild to moderate kidney diseases, the dose may have to be adjusted by your doctor.

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Children

Caution

Aceret 25 Capsule should be used in children only if clinically needed as it may affect growth and bone development. The dose may have to be adjusted by your doctor.

Have a query?

FAQs

Aceret 25 Capsule is used to treat psoriasis, an autoimmune (immune system attacks healthy cells) skin disorder in which the skin becomes scaly, swollen, and itchy.

Aceret 25 Capsule contains 'Acitretin', which belongs to the class of 'retinoids' and is used to treat severe psoriasis. It has anti-inflammatory action and reduces the rashes' redness, scaling, and thickness. It also has antiproliferative properties and slows down the disease's progression by reducing the speed of skin cell growth.

Aceret 25 Capsule may cause vision problems suddenly, especially in the dark. So, inform your doctor immediately if you experience vision problems. Also, refrain from activities such as driving or operating heavy machinery if you have a problem with your vision.

You should not donate blood during the treatment with Aceret 25 Capsule and within three years of discontinuing the treatment. An unborn baby may get harmed if a pregnant woman receives your donated blood.

Aceret 25 Capsule may not affect your immune system. It is not an immunosuppressant. It controls psoriasis by slowing down the progression of the disease.

Aceret 25 Capsule may affect blood glucose levels and should be used with caution in patients with diabetes. You may have to regularly monitor blood glucose levels while using this medicine.

Aceret 25 Capsule may cause side-effects such as dry lips, peeling of the skin, especially the palms of the hands and soles of the feet, nose bleed, scaling and thinning of healthy skin, reddening of the skin, itching, burning sensation on the skin, sticky skin, hair loss, swelling and pain in the area around your nails, fragile nails, inflammation of the eye (conjunctivitis), increased thirst, and feeling cold. If any of these side effects persist or worsen, inform your doctor immediately.

Aceret 25 Capsule should not be used in pregnant women as it may cause harmful effects to the unborn baby or foetus. Consult your doctor for further advice.

No, Aceret 25 Capsule is not an immunosuppressant. It belongs to the class of retinoids used to treat psoriasis.

Drinking alcohol with Aceret 25 Capsule may increase the risk of side effects. So, it is not recommended to take alcohol, especially women of childbearing potential during the treatment and at least 2 months after completing the treatment.

You may notice an improvement in 4-6 weeks of using Aceret 25 Capsule . However, it might take 3-4 months to notice the full benefits.

Aceret 25 Capsule may cause foetal harm; so, do not take Aceret 25 Capsule if you are pregnant or plan to become pregnant within the next 3 years. Aceret 25 Capsule may cause liver damage. Inform the doctor if you have or have ever had liver disease. Consult your doctor immediately if you experience symptoms of liver damage such as nausea, vomiting, pain in the upper right part of the stomach, loss of appetite, and yellowing of the skin or eyes, or dark urine.

Aceret 25 Capsule may not affect semen. However, a small amount of Aceret 25 Capsule is present in the semen of male patients who take this medication. Though it is not known if this affects the foetus, talk to your doctor about the risks of taking Aceret 25 Capsule if your partner is pregnant or plans to become pregnant.

Take Aceret 25 Capsule with the main meal. It should be swallowed as a whole with water; do not crush or chew it.

Avoid becoming pregnant and alcohol consumption during treatment with Aceret 25 Capsule as it might affect the foetus. Do not donate blood while taking Aceret 25 Capsule and for 3 years after treatment. Aceret 25 Capsule may cause blurred vision; so, do not drive or operate machinery unless you are alert. Aceret 25 Capsule may make your skin sensitive to sunlight; therefore, avoid prolonged exposure to sunlight.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - ACE0003

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