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  1. Home
  2. Medicine

  3. Acobose M 50mg/500mg Tablet

Prescription drug
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Acobose M 50mg/500mg Tablet, Pack of 1
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Extra 15% Off with Bank Offers

Composition :

ACARBOSE-50MG + METFORMIN-500MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Acobose M 50mg/500mg Tablet

Acobose M 50mg/500mg Tablet is indicated for the management and treatment of type 2 diabetes, especially in people whose sugar levels are too high and cannot be controlled alone by diet and exercise.

Acobose M 50mg/500mg Tablet contains Metformin and Acarbose. Metformin works by reducing the amount of blood sugar released in the bloodstream by the liver, and Acarbose works by slowing down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose.

Acobose M 50mg/500mg Tablet may cause side effects like diarrhoea, flatulence, and abdominal cramps. Most of these side effects do not need medical attention and will resolve over time. However, consult your doctor if the side effects persist or worsen.

Do not take Acobose M 50mg/500mg Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to prevent any potential interactions.

Uses of Acobose M 50mg/500mg Tablet

Acobose M 50mg/500mg Tablet is used for the management and treatment of type 2 diabetes. The detailed uses of Acobose M 50mg/500mg Tablet are as follows:

  • Type 2 diabetes mellitus: Acobose M 50mg/500mg Tablet manages blood glucose levels when diet and exercise are insufficient.
  • Postprandial hyperglycemia: Acobose M 50mg/500mg Tablet lowers the rise in blood sugar levels after meals by slowing carbohydrate absorption and improving insulin action.
  • Diabetes complications: Acobose M 50mg/500mg Tablet lowers the risk of problems such as nerve damage, kidney disease, and vision issues due to serious diabetic disorders.

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Directions for Use

  • Acobose M 50mg/500mg Tablet should be taken with meals to prevent stomach upset.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Acobose M 50mg/500mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Acobose M 50mg/500mg Tablet helps lower and maintain blood sugar levels in patients with type 2 diabetes not adequately managed by diet and exercise alone.
  • Acarbose is an alpha-glucosidase inhibitor which delays the digestion and absorption of carbohydrates in the intestine, preventing sharp rises in blood sugar after meals.
  • Metformin is a biguanide which improves glucose tolerance, reduces glucose absorption in the intestine, decreases sugar production in the liver, and enhances glucose utilisation by the body.
  • Acobose M 50mg/500mg Tablet provides consistent, gradual blood sugar control suitable for long-term use with minimal side effects.
  • It helps reduce the risk of diabetes-related complications, including eye damage (diabetic retinopathy), kidney damage (diabetic nephropathy), nerve damage (diabetic neuropathy), delayed wound healing and diabetic foot ulcers.

How Acobose M 50mg/500mg Tablet Works

Acobose M 50mg/500mg Tablet contains two medicines namely: 'Metformin' and 'Acarbose'. Metformin is a 'biguanide' that works by reducing the amount of blood sugar released in the bloodstream by the liver, thereby making the body respond in a better way to insulin. On the other hand, Acarbose is an alpha-glucosidase inhibitor which works by slowing down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose, thereby slowing and reducing the absorption of sugar into the blood after every meal.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Acobose M 50mg/500mg Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Acobose M 50mg/500mg Tablet

An overdose of Acobose M 50mg/500mg Tablet may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Acobose M 50mg/500mg Tablet if you are allergic to any of its components.
  • Tell your doctor if you have kidney disease, high ketone levels in blood or urine, heart disease, congestive heart failure, liver disease, or if you are using insulin or other oral diabetes medications.
  • Acobose M 50mg/500mg Tablet may cause lactic acidosis, which occurs due to the overproduction of lactic acid in the blood. If you notice any symptoms, please tell your doctor.
  • You should take small, frequent meals and don't fast while being treated with Acobose M 50mg/500mg Tablet.
  • If you experience symptoms of hypoglycemia (low blood sugar) like sweating, dizziness, dry mouth, dry skin, palpitations, shivering, intense thirst, frequent urination, etc., immediately take 5-6 candies or honey/sugar and consult with a physician.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Inform your doctor if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

verifiedApollotooltip
AcarboseGatifloxacin
Critical
MetforminIomeprol
Critical

Drug-Drug Interactions

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AcarboseGatifloxacin
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Acobose M 50mg/500mg Tablet with Gatifloxacin may cause high or low blood sugar in diabetic patients.

How to manage the interaction:
Although there is a possible interaction between Acobose M 50mg/500mg Tablet and Gatifloxacin, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as sweating, shaking, nervousness, palpitations, or excessive hunger, please contact a doctor. Do not discontinue the medication without consulting a doctor.
MetforminIomeprol
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Iomeprol with Acobose M 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Acobose M 50mg/500mg Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIodamide
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Acobose M 50mg/500mg Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Acobose M 50mg/500mg Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Iotroxic acid with Acobose M 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Acobose M 50mg/500mg Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Acobose M 50mg/500mg Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Acobose M 50mg/500mg Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Iohexol with Acobose M 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Acobose M 50mg/500mg Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIobenzamic acid
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Acobose M 50mg/500mg Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Acobose M 50mg/500mg Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglicic acid
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Ioglicic acid with Acobose M 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Acobose M 50mg/500mg Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Ioglycamic acid with Acobose M 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Acobose M 50mg/500mg Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Acobose M 50mg/500mg Tablet:
Co-administration of Iopydol with Acobose M 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Acobose M 50mg/500mg Tablet with Iopydol is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Engage in regular exercise like cycling, running, walking, jogging, dancing, or swimming for at least 30 minutes. Try to invest at least 150 minutes weekly in exercise.
  • Maintain a healthy body weight to avoid obesity or high blood sugar, which can increase the risk of the onset of diabetes.
  • Consume a low-fat and low-sugar diet. Replace carbohydrates with whole grains, fruits, and vegetables, as carbohydrates are changed into sugars, leading to high blood sugar levels.
  • Try to avoid potatoes as they are high glycemic foods that increase the risk of high sugar in the blood.
  • Limit the consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Acobose M 50mg/500mg Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

You should avoid consuming alcohol with Acobose M 50mg/500mg Tablet as it may lead to high or low blood sugar levels.

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Pregnancy

Caution

Acobose M 50mg/500mg Tablet is a Category B pregnancy drug that is not recommended for pregnant women or given only under the strict guidance of the doctor, as there is no clinical data available on use in pregnant women.

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Breast Feeding

Caution

Avoid nursing your baby while taking Acobose M 50mg/500mg Tablet as this medicine may pass in breast milk.

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Driving

Safe if prescribed

Acobose M 50mg/500mg Tablet does not affect your thinking or driving ability.

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Liver

Caution

Inform your doctor if you are dealing with Liver diseases/conditions, as your doctor may adjust the dose as required.

bannner image

Kidney

Caution

Take Acobose M 50mg/500mg Tablet after the recommendation of a doctor, especially if you have a history of Kidney diseases/conditions. The dosing strength needs to be adjusted by your doctor as required.

bannner image

Children

Unsafe

The use of Acobose M 50mg/500mg Tablet is unsafe for children below 12 years.

FAQs

Acobose M 50mg/500mg Tablet is used for the management and treatment of type 2 diabetes.

Avoid taking digoxin with Acobose M 50mg/500mg Tablet, as it may lead to serious drug interaction. Consult your doctor if you need to take both medicines together, your doctor may adjust the dose appropriately to use safely.

Acobose M 50mg/500mg Tablet works by reducing the amount of blood sugar released in the bloodstream by the liver and slowing down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose.

Acobose M 50mg/500mg Tablet is contraindicated in the condition of diabetic ketoacidosis or lactic acidosis, as it may lead to overload of acids or ketones in your blood, leading to severe life-threatening conditions, as the kidneys may not be able to remove it.

You should try to take small meals at regular intervals and should not skip your meals, as it can help Acobose M 50mg/500mg Tablet work more effectively by utilising glucose in the right manner. Fasting is dangerous for a diabetes patient taking Acobose M 50mg/500mg Tablet as it would lower the blood sugar level, leading to hypoglycemia.

No, a person should continue taking Acobose M 50mg/500mg Tablet as much as the doctor has prescribed for the treatment of type 2 diabetes. You should not stop discontinuing Acobose M 50mg/500mg Tablet suddenly, as it may worsen the symptoms of type 2 diabetes and increase the blood sugar level, leading to hyperglycemia.

Other Info - AC39226

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 23, 2025 | 8:20 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.9999.pdf
  2. https://www.drugs.com/food-interactions/acarbose.html
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