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ACTORISE 200MG INJECTION

Manufacturer/Marketer

CIPLA LTD

Consume Type

PARENTERAL

In Stock

Prescription Required
Product Details

About ACTORISE 200MG INJECTION

ACTORISE 200MG INJECTION belongs to the class of medication called 'blood-forming agent'  primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). ACTORISE 200MG INJECTION helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia.

ACTORISE 200MG INJECTION contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. ACTORISE 200MG INJECTION is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, ACTORISE 200MG INJECTION stimulates the production of this protein in the bone marrow. 

ACTORISE 200MG INJECTION will be injected by the healthcare provider. Do not self-administer. The most common side effects of ACTORISE 200MG INJECTION are shortness of breath,  cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of ACTORISE 200MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to darbepoetin alfa or epoetin alfa, please inform your doctor before taking ACTORISE 200MG INJECTION to avoid any complications. Also, mention all the other medications you are taking to affect the way ACTORISE 200MG INJECTION works. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be signs that the body has stopped responding to ACTORISE 200MG INJECTION. 

Uses of ACTORISE 200MG INJECTION

Anaemia (in cancer and chronic kidney disease)
 

Medicinal Benefits

ACTORISE 200MG INJECTION is a human-made form of naturally occurring erythropoiesis-stimulating protein or erythropoietin (a hormone produced by the kidney's specialized cells and is responsible for protecting red blood cells against destruction and also stimulates the cells of bone marrow to produce more amount of red blood cells). Deficiency of erythropoietin happens when a person is suffering from chronic kidney diseases, which in turn cause low red blood cells count causing anaemia.  This medicine is primarily indicated for treating anaemia (low red blood cell count) in persons with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer except for bone marrow or blood cells' cancer. ACTORISE 200MG INJECTION contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. 

Directions for Use

ACTORISE 200MG INJECTION will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ACTORISE 200MG INJECTION

  • Shortness of breath
  • Cough
  • Hypotension (low blood pressure)
  • Headache
  • Body aches
  • Diarrhoea
  • Injection site pain 
  • Abdominal pain (stomach pain) 

 

In-Depth Precautions and Warning

Drug Warnings

ACTORISE 200MG INJECTION can enhance the risk of serious heart problems including heart attack so tell your doctor immediately if you notice shortness of breath, sudden numbness or weakness, chest pain, or trouble speaking or understanding. This medicine may also shorten survival time in some people with certain types of cancer. Inform your doctor before taking ACTORISE 200MG INJECTION if you have heart disease, high blood pressure, kidney disease, stroke, heart attack, blood clot, seizure, or latex allergy. Do not take ACTORISE 200MG INJECTION if you are pregnant or breastfeeding unless prescribed by the doctor. ACTORISE 200MG INJECTION may affect a person's ability to drive as it may cause convulsion during initial days of treatment, so a person taking ACTORISE 200MG INJECTION should avoid driving or operating any machine. ACTORISE 200MG INJECTION should not be given to children below 12 years of age, as safety and effectiveness have not been established. Avoid consuming alcohol along with ACTORISE 200MG INJECTION as it could lead to increased dizziness and sleepiness. 

Drug Interactions

Drug-Drug Interactions: ACTORISE 200MG INJECTION may have interaction with other chemotherapy drugs (thalidomide),  immunosuppressant medication (cyclosporine),  antihypertensive medicines (captopril). 

Drug-Food Interactions: Avoid alcohol consumption while taking ACTORISE 200MG INJECTION as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: ACTORISE 200MG INJECTION may have interactions with disease conditions such as seizures, hemodialysis, hypertension, and thrombotic events
 

Drug-Drug Interactions Checker List:

  • THALIDOMIDE
  • CYCLOSPORINE
  • CAPTOPRIL
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking ACTORISE 200MG INJECTION as it may increase dizziness and sleepiness.

    • Safety Warning

      Pregnancy

      caution

      Avoid taking ACTORISE 200MG INJECTION if you are pregnant unless prescribed by a doctor as ACTORISE 200MG INJECTION is a pregnancy category C drug. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor before taking ACTORISE 200MG INJECTION; your doctor will decide whether ACTORISE 200MG INJECTION can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      unsafe

      ACTORISE 200MG INJECTION causes convulsions (seizures), especially during the initial months of treatment. So, it is better not to drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      ACTORISE 200MG INJECTION should not be given to children as the safety and efficacy have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Limit the consumption of fluids, salt, potassium, phosphorous, and other electrolytes.
    • Eat a low-protein diet, and get enough calories from the foods if you are losing weight.
    • Eat foods that are high in vitamin B12, iron, and folic acid can fulfil the deficiencies of happed in kidney disease.
    • Include a little number of healthy fats in your diet that give you enough energy to be active during the day; however, try to limit fats that make you fatty. Try to include olive oil, peanut oil, and corn oil into your diet.
    • Rest well, get plenty of sleep.
    • Avoid smoking and alcohol consumption.
    • Using essential oils for massages can help increase circulation.

    Special Advise

    • Certain diagnostic tests like Complete blood count (CBC) can help check the count of red blood cells.
    • Have regular haemoglobin tests to check whether there is an improvement in the level of red blood cells after taking ACTORISE 200MG INJECTION or not.

    Other Information (ACT0375)

    This item is Not Returnable.

    Expires on or after - Apr-24

    Patients Concern

    Disease/Condition Glossary

    Anaemia: It occurs when the body has a lower amount of red blood cells or haemoglobin than normal haemoglobin (iron-rich the protein responsible for allowing red blood cells to carry more oxygen from the lungs to the rest of the body).  In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. Symptoms of anaemia in chronic kidney disease include fatigue or tiredness, shortness of breath, ashen skin, weakness, body aches, chest pain, dizziness, fainting, fast or irregular heartbeat, headache, sleep problems, and trouble in concentrating. 

    FAQs

    How should be ACTORISE 200MG INJECTION stored?

    It is suggested to store the ACTORISE 200MG INJECTION in the refrigerator and protect it from light. However, a person should not freeze it.

    I have high blood sugar, should I tell it to a doctor before taking ACTORISE 200MG INJECTION?

    It is advised to tell your doctor about your medical conditions like heart disease, high blood pressure, kidney disease, a stroke, heart attack, or blood clot, a seizure, a latex allergy to avoid any type of medical condition.

    In which conditions ACTORISE 200MG INJECTION should not be taken?

    A person who is allergic to any chemical compound present in ACTORISE 200MG INJECTION or have uncontrolled/untreated high blood pressure, or ever had pure red cell aplasia (a type of anaemia) caused by using darbepoetin alfa, or epoetin alfa is not allowed to take a name.

    Can pregnant women use ACTORISE 200MG INJECTION?

    Consult your doctor before taking ACTORISE 200MG INJECTION if you are pregnant or planning for pregnancy. Your doctor will prescribe ACTORISE 200MG INJECTION only if the benefits outweigh the risks.

    How does ACTORISE 200MG INJECTION work?

    ACTORISE 200MG INJECTION contains a protein 'Darbepoetin alfa', which works by providing signals to the bone marrow to make more red blood cells. As in chronic kidney disease, the kidney gets damaged and doesn't filter the blood in the way it should be leading to anemia.

    PRODUCT SUBSTITUTES

    ACTORISE 200MG INJECTION

    Country Of Origin

    India

    Manufacturer/Marketer address

    Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

    Disclaimer

    While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

    Price :₹11596.10

    MRP ₹13642.50

    15%off

    (Inclusive of all taxes)

    Provide Delivery Location

    Vial

    1 Injection in 1 Vial