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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Addnok 0.2 mg Tablet is used to treat opioid addiction (narcotics) like morphine, heroin, etc. It contains Buprenorphine, an opioid partial agonist-antagonists that prevent withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It has been approved for the treatment of narcotic-use disorders. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

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Composition :

BUPRENORPHINE-0.2MG

Manufacturer/Marketer :

Rusan Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Addnok 0.2 mg Tablet

Addnok 0.2 mg Tablet is used to treat opioid addiction (narcotics) like morphine, heroin, etc. It is also used to treat, prevent and treat moderate to severe pain. Drug addiction, also called substance use disorder, is a disease that affects a person's brain and behaviour and leads to an inability to control the use of a legal or illegal drug or medication.

Addnok 0.2 mg Tablet contains 'Buprenorphine', an opioid partial agonist-antagonists that prevent withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It has been approved for the treatment of narcotic-use disorders. A combination of buprenorphine and naloxone is prescribed for use in the treatment of opioid dependence. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

Addnok 0.2 mg Tablet should be used as prescribed by your doctor. The dose will be decided based on your medical condition. This medicine may cause certain side effects, in drowsiness, dry mouth, vomiting, blurred vision, constipation, dizziness or tiredness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Addnok 0.2 mg Tablet should be avoided if you are allergic to it. Do not take Addnok 0.2 mg Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Addnok 0.2 mg Tablet is not recommended for children below 18 years of age. Addnok 0.2 mg Tablet is a habit-forming drug, and hence, there is a risk of dependence on Addnok 0.2 mg Tablet . Therefore, before stopping Addnok 0.2 mg Tablet , contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feeling. Addnok 0.2 mg Tablet may decrease fertility in men and women. Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease before starting treatment with Addnok 0.2 mg Tablet . Avoid consuming alcohol along with Addnok 0.2 mg Tablet as it could lead to increased dizziness.

Uses of Addnok 0.2 mg Tablet

Addnok 0.2 mg Tablet is used in the treatment of opioid (drug) addiction and pain. The detailed uses of Addnok 0.2 mg Tablet are as follows:
• Pain Relief: Addnok 0.2 mg Tablet is commonly used to alleviate mild to moderate pain, such as headaches, dental pain, or muscle aches.
• Post-surgical Pain Management: Addnok 0.2 mg Tablet can be prescribed after surgical procedures to manage pain and aid in recovery.
• Opioid dependence and addiction: Addnok 0.2 mg Tablet is used in management of opioid dependence and addiction.

Directions for Use

  • Addnok 0.2 mg Tablet can be taken with or without food. However, it is often recommended to take it on an empty stomach for faster absorption. Follow your doctor’s advice if they provide specific instructions regarding food intake.
  • Take it exactly as prescribed by your healthcare provider. It is usually taken once a day, but follow your doctor’s specific recommendations on the timing and dose.
  • Place the tablet under your tongue and allow it to dissolve completely. Do not chew, swallow, or break the tablet. The tablet may take several minutes to fully dissolve, and it’s important to let it dissolve naturally for proper absorption.
  • While the tablet is dissolving, avoid eating, drinking, or talking, as this may affect how the medication is absorbed.

Medicinal Benefits

The Addnok 0.2 mg Tablet contains Buprenorphine as a substitution (replacement) treatment in patients addicted to opioid drugs (heroin, morphine, etc.). It prevents or reduces the unpleasant withdrawal symptoms experienced when addicts stop using opioid drugs. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, Addnok 0.2 mg Tablet has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses.

How Addnok 0.2 mg Tablet Works

Addnok 0.2 mg Tablet contains 'Buprenorphine', an opioid partial agonist-antagonists that prevent withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It has been approved for the treatment of narcotic-use disorders. A combination of buprenorphine and naloxone is prescribed for use in the treatment of opioid dependence. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

Storage

Store in a cool and dry place away from sunlight
Side effects of Addnok 0.2 mg Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.

What if I have taken an overdose of Addnok 0.2 mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. The most common signs and symptoms of Addnok 0.2 mg Tablet are blue, pale lips, cold and clammy skin, coma, decreased blood pressure, fainting, miotic pupils, severe drowsiness, slowed and shallow breathing. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Please do not stop taking Addnok 0.2 mg Tablet suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to Addnok 0.2 mg Tablet or any other medicines, please tell your doctor.  Do not take Addnok 0.2 mg Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Addnok 0.2 mg Tablet is not recommended for children below 18 years of age.  Avoid consuming alcohol with Addnok 0.2 mg Tablet as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. Addnok 0.2 mg Tablet should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants.

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical
How does the drug interact with Addnok 0.2 mg Tablet:
Using alvimopan together with Addnok 0.2 mg Tablet can cause side effects (abdominal pain, nausea, vomiting, and diarrhea).

How to manage the interaction:
Taking Alvimopan with Addnok 0.2 mg Tablet is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Taking Ziprasidone with Addnok 0.2 mg Tablet can increase the risk of serious side effects.

How to manage the interaction:
Taking Ziprasidone with Addnok 0.2 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
When buspirone is used with Addnok 0.2 mg Tablet it may result in central nervous system depression, significant adverse effects (respiratory distress, unconsciousness).

How to manage the interaction:
Co-administration of buspirone along with Addnok 0.2 mg Tablet can lead to an interaction, it can be taken if recommended by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Using Lurasidone together with Addnok 0.2 mg Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Despite the fact that Addnok 0.2 mg Tablet and Lurasidone interact, it can be taken if prescribed by a doctor. Consult a doctor if you develop dizziness, drowsiness, difficulty concentrating, or problems in judgment, reaction speed, or movement control. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Using Addnok 0.2 mg Tablet together with Eslicarbazepine can cause central nervous system depression.

How to manage the interaction:
Concomitant administration of Addnok 0.2 mg Tablet alongside eslicarbazepine can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Using Pregabalin together with Addnok 0.2 mg Tablet causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Addnok 0.2 mg Tablet and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Coadministration of Cyclobenzaprine with Addnok 0.2 mg Tablet can increase the risk of developing side effects.

How to manage the interaction:
Coadministration of Addnok 0.2 mg Tablet with cyclobenzaprine can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor if you experience shortness of breath, chest discomfort, or palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Co-administration of Addnok 0.2 mg Tablet and Gabapentin may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Addnok 0.2 mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
BuprenorphineChloral hydrate
Severe
How does the drug interact with Addnok 0.2 mg Tablet:
Using Addnok 0.2 mg Tablet together with Chloral hydrate can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Addnok 0.2 mg Tablet with Chloral hydrate can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and be aware of any changes. Doctor can recommend other options that won't cause any problems. If you experience trouble breathing, feeling too sleepy, or having difficulty with your nervous system - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
When Addnok 0.2 mg Tablet is used with gatifloxacin, it may lead to significant adverse effects (respiratory difficulties or unconsciousness).

How to manage the interaction:
Concomitant administration of Addnok 0.2 mg Tablet alongside gatifloxacin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. You should avoid driving or operating hazardous machinery while taking these medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as swimming or walking.
  • Drink plenty of water while taking Addnok 0.2 mg Tablet to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking Addnok 0.2 mg Tablet .
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

Therapeutic Class

OPIOID ANTAGONISTS
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Alcohol

Unsafe

Avoid consumption of alcohol while using Addnok 0.2 mg Tablet as it may lead to a worsening of side effects of this medicine.

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Pregnancy

Unsafe

Addnok 0.2 mg Tablet is not recommended for use during pregnancy as it may cause life-threatening withdrawal symptoms in the newborn. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Addnok 0.2 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It may be unsafe to use during breastfeeding as it passes into breastmilk and may cause sleepiness and decreased heart rate in your infant. It is not recommended for use in breastfeeding. Hence, if you are breastfeeding, inform your doctor before taking Addnok 0.2 mg Tablet . Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Addnok 0.2 mg Tablet may cause dizziness, blurred vision or drowsiness in some people. It is an offence to drive if Addnok 0.2 mg Tablet affects you. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Addnok 0.2 mg Tablet .

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Addnok 0.2 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Addnok 0.2 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Addnok 0.2 mg Tablet is not recommended for children below 18 years of age as safety and effectiveness have not been established.

Have a query?

FAQs

Addnok 0.2 mg Tablet is used to treat Opioid (drug) addiction. It also provides pain relief.

Addnok 0.2 mg Tablet consists of Buprenorphine is an opioid partial agonist. It prevents withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It also provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

Yes, Addnok 0.2 mg Tablet may cause withdrawal symptoms such as sweating, feeling hot and cold, runny eyes and nose, feeling or being sick, diarrhoea, stomach cramps, poor sleep, and just feeling awful. Therefore, if you experience difficulty while taking Addnok 0.2 mg Tablet , do not stop taking it suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.

Chronic use of opioids may cause reduced fertility (ability to have children) in females and males of reproductive potential. It is not known whether these effects on fertility are reversible. However, it is essential to talk to your doctor before starting treatment with Addnok 0.2 mg Tablet if you think you may want to have a baby in the future.

No, you are not recommended to take Addnok 0.2 mg Tablet with antidepressants (medicines used to treat depression) and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Addnok 0.2 mg Tablet may cause life-threatening respiratory depression and death have occurred. However, please consult a doctor before taking Addnok 0.2 mg Tablet with other medicines.

Yes, Addnok 0.2 mg Tablet may cause addiction, especially if taken for a prolonged time. Therefore, Addnok 0.2 mg Tablet should be given only for a short duration under strict medical supervision, particularly to patients susceptible to drug abuse. Take Addnok 0.2 mg Tablet only as advised by a doctor, as overuse or misuse of Addnok 0.2 mg Tablet can lead to overdose or death.

Some prescription-based opioid pain medications include codeine, fentanyl, hydromorphone, meperidine morphine, oxymorphone, oxycodone, hydrocodone and propoxyphene.

Yes, Addnok 0.2 mg Tablet is an opiate, a controlled substance, and a painkiller. Addnok 0.2 mg Tablet is also used as an opioid blocker for treating opioid addiction. Although it has a lower risk of abuse compared to other opioids, it can still be addictive.

Addnok 0.2 mg Tablet can cause depression. If you are experiencing mood changes or feelings of depression, it is important to talk with your doctor to determine whether Addnok 0.2 mg Tablet might be causing it or if other factors are involved.

Addnok 0.2 mg Tablet may cause side effects such as weakness, anxiety, nervousness, dizziness, drowsiness, headache, constipation, and diarrhoea, nausea, vomiting and sweating. Most of these side effects are temporary and do not require any medical attention, as they will gradually reduce over time. Contact a doctor, if these side effects continue for longer durations.

Country of origin

India

Manufacturer/Marketer address

58-D, Government Industrial Estate, Charkop, Kandivli (W), Mumbai ? 400 067 (India).
Other Info - ADD0002

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