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About PREGABALIN

PREGABALIN belongs to a group of medications called 'anti-convulsant' primarily used in the prevention of neuropathic pain, epilepsy (seizures episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve). Neuropathic pain is a chronic nerve pain usually caused by damaged nerves due to a variety of diseases like diabetes, shingles (viral infection that causes a painful rash), or spinal cord injury, injuries to tissue, muscles, or joints.

PREGABALIN contains 'Pregabalin' that works by calming the damaged or overactive nerves in your body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

PREGABALIN can be taken with or without a meal with a full glass of water. A person taking PREGABALIN might experience side effects like dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and thinking abnormal (primarily difficulty with concentration/attention). Although, not every person faces the side effects of PREGABALIN, and even some of the unpleasant effects of PREGABALIN do not require medical attention.

The use of PREGABALIN restricted in persons who are a known history of allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing symptoms of suicidal ideation or behaviour, drug addiction, chronic pulmonary insufficiency, muscle pain, soreness, or weakness, kidney, liver, or heart diseases.  Caution is required before giving PREGABALIN to the pregnant or breastfeeding women. The safety and effectiveness in children less than 18 years of age have not been established, so PREGABALIN should not be given to them.

Uses of PREGABALIN

Neuropathic pain (nerve pain), Epilepsy (seizures/fits), Fibromyalgia (musculoskeletal pain)

Medicinal Benefits

PREGABALIN belongs to a group of medications called 'anticonvulsants' used to prevent neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in your body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body. Overall it reduces the pain which has been damaged or irritated due to conditions like chronic conditions, diabetes, trauma, or epilepsy. Off label use of PREGABALIN is in the treatment of anxiety disorder to calm overactive nerve signals.

Directions for Use

Oral tablet/capsule: Use PREGABALIN exactly as prescribed by a doctor. Take PREGABALIN with food for better absorption and swallow whole with a glass of water. Do not crush, chew, or break it. Oral solution: If you are prescribed PREGABALIN in oral solution form, shake the bottle well before use and take PREGABALIN with food. Take PREGABALIN in doses as prescribed by a doctor with the help of a measuring cup provided.

Storage

Store in a cool and dry place away from sunlight

Side Effects of PREGABALIN

A person taking PREGABALIN might experience side effects like dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and thinking abnormal (primarily difficulty with concentration/attention). Although, not every person faces the side effects of PREGABALIN, and even some of the unpleasant effects of PREGABALIN do not require medical attention.

In-Depth Precautions and Warning

Drug Warnings

Do not take PREGABALIN if you are known to be allergic to PREGABALIN. Inform your doctor if you have symptoms of suicidal ideation or behaviour, drug addiction, chronic lung diseases, muscle weakness, heart problems, liver/kidney impairment. Caution is required before giving PREGABALIN to the pregnant or breastfeeding women. PREGABALIN may affect a person's ability to drive soon should avoid driving or operating any machine. The safety and effectiveness in children less than 18 years of age have not been established, so PREGABALIN should not be given to them. Taking PREGABALIN with opioids analgesics or pain killers like oxycodone can cause respiratory failure, coma, and even leading to death, so avoid its intake together. If you are taking any sleeping pills or tranquillizers, let your doctor know about this as PREGABALIN interacts with these drugs to cause sleepiness, drowsiness and dizziness and affect your daily activity. Immediately contact a doctor if you have swelling of your face, mouth, tongue, lips, gums, neck, or throat (angioedema).

Drug Interactions

Drug-Drug Interaction: PREGABALIN may interact with a painkiller (morphine, fentanyl, oxycodone, tramadol, codeine) and medicines used for treating anxiety (lorazepam, diazepam, clonazepam).

Drug-Food Interaction: PREGABALIN may interact with alcohol. Therefore, avoid consuming alcohol while taking PREGABALIN as it may increase side effects such as drowsiness, dizziness, or difficulty in concentrating. 

Drug-Disease Interaction: If you have suicidal ideation or behavior, drug addiction, chronic pulmonary insufficiency, heart problems, liver/kidney impairment, inform your doctor before taking PREGABALIN.

Safety Advice

  • Safety Warning

    Alcohol

    Consult Your Doctor

    It is unsafe to consume alcohol since it may worsen the side effects like dizziness and sleepiness.

  • Safety Warning

    Pregnancy

    PREGABALIN is a category C pregnancy drug. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing PREGABALIN.

  • Safety Warning

    Breast Feeding

    The safe use of PREGABALIN in breastfeeding mothers has not yet been established. So, it should be used in breastfeeding women only when prescribed by a doctor. Your doctor will weigh the benefits and potential risks before prescribing PREGABALIN. However, it is not recommended please consult your doctor before starting PREGABALIN.

  • Safety Warning

    Driving

    Do not drive or operate machinery if you experience dizziness or drowsiness while using PREGABALIN. PREGABALIN can also sometimes cause blurry/double vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

  • Safety Warning

    Liver

    Take PREGABALIN with caution, especially if you have or had a history of liver disease/conditions. The dose may be adjusted by your doctor as required.

  • Safety Warning

    Kidney

    Take PREGABALIN with caution, especially if you have or had a history of kidney disease/conditions. The dose may be adjusted by your doctor as required.

Habit Forming

Yes

Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables, whole grains, omega-3 rich foods. Avoid fried foods, high-fat dairy products, pastries, and processed foods as they may worsen neuropathic pain, anxiety. Limit your sodium and potassium diet.
  • Do regular exercise and maintain a healthy weight.
  • Avoid consumption of alcohol as it may increase dizziness or drowsiness, also cause toxic effects on nerve tissue.

 

Special Advise

Do not take PREGABALIN for a prolonged time; it may lead to mental or physical dependence on PREGABALIN.

Patients Concern

Disease/Condition Glossary

Neuropathic pain (nerve pain): It is a chronic nerve pain condition usually caused by damaged or irritated nerves due to conditions like diabetes, shingles (viral infection with painful rash), spinal cord injury, or injuries to tissue/muscles/joints. Symptoms of nerve pain sensation are hot, burning, throbbing, shooting, stabbing, sharp, cramping tingling, numbness, pain, and needles. 

Fibromyalgia (musculoskeletal pain): is a common and chronic condition that may cause pain, muscle stiffness and tenderness, tiredness, and difficulty falling asleep or staying asleep and mental distress, an impact on physical and social functioning and overall quality of life.

Epilepsy (fits): It is a nervous system disorder with a sudden rush of electricity in the brain due to disturbed nerve cell (neuron) activity in the brain. Seizures are of two types, namely: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures can make people confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

FAQs

How does PREGABALIN work?

PREGABALIN is an anticonvulsant drug used for the treatment of neuropathic pain (neuropathy), musculoskeletal pain (fibromyalgia), and epilepsy (fits). In nerve pain (neuropathy), and fibromyalgia (musculoskeletal pain) it works by blocking the pain centre that interferes with pain messages that travel through the brain and spine (central nervous system). In epilepsy, it prevents episodes of fits by reducing the abnormal electrical activity in the brain and calming the overactive nerves.

Can PREGABALIN cause weight gain?

Yes, PREGABALIN may cause weight gain because as it increases your hunger. However, regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Please consult the doctor if you have any further concerns to keep your weight stable.

Can I get addicted to PREGABALIN?

Some people have become addicted to PREGABALIN after taking it for a long time. If you experience this, you will have withdrawal symptoms after you stop taking the medicine. Talk to your doctor if you are concerned you are becoming physically dependant on PREGABALIN.

Can I drink alcohol while taking PREGABALIN?

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and drowsiness.

Can I drive while taking PREGABALIN?

Do not drive or operate machinery if you experience dizziness or drowsiness while using PREGABALIN. PREGABALIN can also sometimes cause double/ blurry vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

Can I take PREGABALIN with painkillers like tramadol?

No, you are not recommended to take PREGABALIN with tramadol as co-administration of these medicines may cause breathing problems, drowsiness, and even lead to a stage of coma. So, before using PREGABALIN with pain killers like oxycodone or any other opioids analgesics, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

What are the most common side effects of PREGABALIN?

Dizziness, blurry vision, weight gain, sleepiness, trouble concentrating, swelling of hands and feet and dry mouth are some of the common side effects which might occur in people taking PREGABALIN for a longer time.

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