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compositionComposition:DOXORUBICIN-2MG/ML
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Adrikaas-50 Injection 25 ml is an anti-cancer medicine used to treat cancer. It contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs; this causes double-helix DNA to be uncoiled, destroying DNA and RNA synthesis. Thus, it treats cancer.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DOXORUBICIN-2MG/ML

Manufacturer/Marketer :

ANAKAAS LIFE BIO SCIENCE PVT LTD.

Consume Type :

Parenteral

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About Adrikaas-50 Injection 25 ml

Adrikaas-50 Injection 25 ml is a prescription medicine given as an injection to treat several types of cancer, including breast, ovarian, bladder, and thyroid cancers, as well as certain blood cancers. Its medical purpose is to target and slow down or stop the growth of abnormal cancer cells in the body. By destroying these fast-growing cells, it helps control the spread of the disease.

Because this medicine is a highly specialised cancer treatment, it is given at specific intervals determined by your healthcare team to allow your body time to recover between cycles. It is injected directly into a vein by a trained medical professional in a hospital or clinic setting, meaning there are no home food instructions. However, maintaining a balanced diet, resting well, and staying highly hydrated can help support your body during treatment.

While receiving Adrikaas-50 Injection 25 ml, you may experience common side effects such as nausea, temporary hair loss, fatigue, and mouth sores. It is vital to consult your doctor immediately if you experience serious side effects, such as chest pain, breathing difficulties, signs of infection, or pain and swelling at the injection site.

Before starting treatment, tell your doctor if you have a history of heart disease, liver damage, or low blood cell counts. Do not take this if you have severe heart problems, extremely low blood cell counts, or have had a severe allergic reaction to similar cancer medications.

This medicine can interact with other drugs, such as certain vaccines or other chemotherapy treatments, which can increase the risk of side effects or reduce how well the medicine works. Always consult your doctor if you are pregnant, planning to become pregnant, breastfeeding, or if you are caring for an elderly patient, as special precautions are needed.

Uses of Adrikaas-50 Injection 25 ml

Adrikaas-50 Injection 25 ml is used to treat several types of cancer. The detailed uses of Adrikaas-50 Injection 25 ml are as follows:

  • Breast cancer: It helps by targeting and destroying cancer cells within the breast tissue to prevent the disease from spreading.
  • Ovarian cancer: It works to slow down and stop the multiplication of abnormal cells in the ovaries.
  • Bladder cancer: It assists in shrinking or eliminating cancerous tumours located in the bladder.
  • Leukaemia: It helps control the overproduction of abnormal white blood cells in the bone marrow.
  • Lymphoma: It aids in reducing cancerous cells in the lymphatic system to manage the disease.

Key Benefits

Adrikaas-50 Injection 25 ml helps treat certain types of cancer by slowing or stopping the growth of rapidly dividing cancer cells. When used as prescribed, it helps control the disease, reduce tumour burden, and support better treatment outcomes.

  • Helps Control Cancer Growth: By targeting rapidly growing cancer cells, this medicine helps slow or stop their growth, reducing tumour size and limiting the progression of the disease.
  • Relieves Cancer-Related Symptoms: As tumours shrink or stop growing, this medicine may help reduce pain, pressure, and other symptoms caused by cancer, improving daily comfort and quality of life.
  • Supports Long-Term Treatment Goals: By helping prevent cancer cells from multiplying and spreading, this medicine supports remission when achievable, reduces the risk of disease progression, and contributes to improved long-term treatment outcomes.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Adrikaas-50 Injection 25 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Adrikaas-50 Injection 25 ml Works

Adrikaas-50 Injection 25 ml contains doxorubicin, which works by targeting the genetic material inside cancer cells. Cancer cells multiply rapidly, which requires them to constantly copy their DNA. This medicine binds to the DNA of these rapidly dividing cells and blocks a key enzyme they need to repair and replicate themselves. By damaging the DNA and stopping this enzyme from working, Adrikaas-50 Injection 25 ml prevents the cancer cells from dividing and growing. This ultimately leads to the self-destruction of the abnormal cells, helping to control and reduce the spread of cancer throughout the body.
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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Alcohol consumption is not recommended.

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Pregnancy

Unsafe

Adrikaas-50 Injection 25 ml is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Adrikaas-50 Injection 25 ml. Use reliable methods of birth control while on treatment with Adrikaas-50 Injection 25 ml.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Adrikaas-50 Injection 25 ml. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Caution

Adrikaas-50 Injection 25 ml may cause dizziness and tiredness; therefore, avoid driving vehicles or operating machinery until you return to normal.

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Liver

Caution

Adrikaas-50 Injection 25 ml should be used with caution in patients with liver impairment. However, this medicine is contraindicated in patients with severe liver disease. If you have a pre-existing or a history of liver disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative, if necessary, based on your condition.

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Children

Consult your doctor

Adrikaas-50 Injection 25 ml is used to treat neuroblastoma (cancer that starts in nerve cells and primarily affects children) and Wilms' tumor (a form of kidney cancer that affects children). Your doctor may recommend a suitable dosage based on your child's condition.

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Heart

Caution

Adrikaas-50 Injection 25 ml should be avoided or used with extreme caution in people with heart problems due to its high risk of cardiotoxicity. If necessary, close cardiac monitoring and consideration of safer alternatives are essential.

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Geriatrics

Caution

Geriatric patients can receive Adrikaas-50 Injection 25 ml, but with extra caution due to increased risks of heart damage and bone marrow suppression. Close monitoring of cardiac function and organ health is essential throughout treatment.

What if I have taken an overdose of Adrikaas-50 Injection 25 ml

Since this medicine is given by trained medical professionals in a controlled clinical environment, an overdose is highly unlikely. However, if you suspect an error has occurred or experience sudden, severe symptoms after an injection, seek immediate medical attention.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water and clear fluids to help flush the medicine through your kidneys and prevent dehydration from nausea.
  • Eat small, frequent meals: If you experience nausea, eating smaller portions throughout the day rather than three large meals can help keep your stomach settled.
  • Choose soft, bland foods: To manage or prevent painful mouth sores, avoid spicy, acidic, or crunchy foods, and opt for soft, easy-to-chew options instead.
  • Practice strict food safety: Because your immune system may be weakened, avoid raw or undercooked meats, eggs, and seafood, and wash all fruits and vegetables thoroughly.
  • Protect your skin from the sun: This treatment can make your skin more sensitive to sunlight, so wear protective clothing and apply broad-spectrum sunscreen when outdoors.
health query

Have a query?

How Soon It Starts Working

The time required for Adrikaas-50 Injection 25 ml to start to work: The peak effect of Adrikaas-50 Injection 25 ml starts immediately after the IV administration. The time for which the effects of Adrikaas-50 Injection 25 ml last: The peak effect of Adrikaas-50 Injection 25 ml lasts for 1 to 2 days.

What if you forget to take Adrikaas-50 Injection 25 ml

If you miss an appointment for your injection, contact your doctor or clinic immediately to reschedule. Keeping a consistent treatment schedule is very important for the success of your therapy.

Storage

• In a clinical setting, vials of Adrikaas-50 Injection 25 ml are stored in a refrigerator at 2°C to 8°C (36°F to 46°F) and kept in their original packaging to protect them from light.

Drug Warnings

  • Monitor the injection site: Tell your nurse or doctor immediately if you feel any burning, stinging, or pain while the injection is being given, as this can indicate the medicine is leaking outside the vein.
  • Keep all blood test appointments: Regular blood tests are required to monitor your blood cells and ensure it is safe for you to receive your next dose.
  • Watch your heart health: Report any heart palpitations, rapid heartbeats, or sudden ankle swelling to your doctor right away, as this medicine can affect your heart muscles.
  • Avoid live vaccines: Do not receive any live vaccines while undergoing treatment, as your weakened immune system may not be able to handle them safely.
  • Avoid crowds and sick people: Because your white blood cell count may drop, take precautions to avoid catching infections from others.
  • Expect urine colour changes: Do not be alarmed if your urine turns a reddish or pinkish colour for a day or two after your injection; this is a harmless effect of the medicine's natural colour.

verifiedApollotooltip

Certain heart medications or other cancer drugs: May increase the risk of heart damage when combined with Adrikaas-50 Injection 25 ml.

  • Live vaccines: May cause severe infections because the body's immune defence is lowered.
  • Seizure medicines: Adrikaas-50 Injection 25 ml may lower the absorption of these drugs, making them less effective.

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verifiedApollotooltip
  • There are no major, clinically established food interactions with this injectable medicine. However, it is always best to discuss your overall diet and use of herbal supplements with your healthcare team.

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Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

No. You should avoid becoming pregnant while receiving Adrikaas-50 Injection 25 ml because it can harm an unborn baby. This medicine may also affect fertility by disrupting menstrual cycles in women or reducing sperm production in men, although pregnancy is still possible. Both men and women should use effective contraception during treatment and for the period recommended by their doctor after the final dose. Talk to your doctor about fertility preservation or family planning before starting treatment.
If you notice burning, stinging, pain, swelling, or redness around the injection site during your treatment, tell your nurse or doctor immediately. Adrikaas-50 Injection 25 ml is a vesicant, meaning it can cause serious skin and tissue damage if it leaks outside the vein. Prompt treatment can help reduce the risk of injury.
Yes, temporary hair loss is a very common side effect of Adrikaas-50 Injection 25 ml. This usually affects the scalp, but can also affect eyebrows, eyelashes, and body hair. Hair typically begins to grow back after the treatment cycles are fully completed. Talk to your doctor if you have concerns about hair loss.
The medicine itself has a deep red colour, which your body naturally filters out through your kidneys. This can cause your urine to look reddish or pinkish for 1 to 2 days after your injection. This is expected and harmless, but if it lasts longer, talk to your doctor.
Adrikaas-50 Injection 25 ml is given as an injection or a slow drip (infusion) directly into a vein. This process is performed by trained healthcare professionals in a hospital or specialised clinic to ensure it is done safely. Talk to your doctor about your specific treatment schedule.
Yes, this medicine can sometimes affect the heart muscles, especially at higher cumulative doses. Your doctor will likely test your heart function before and during your treatment to ensure it remains safe for you to continue. Talk to your doctor if you experience shortness of breath or swollen ankles.
You should avoid receiving live vaccines while using this medicine, as your immune system is weakened and you could become sick. It is safe to discuss any scheduled or needed vaccines with your healthcare team before starting therapy. Talk to your doctor before getting any immunisations.
The medicine is processed by your liver and slowly cleared from your body over several days, though its effects on cells can last longer. Your doctor schedules your treatment cycles carefully to allow your healthy cells time to recover between doses. Talk to your doctor for more details about your specific cycle.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

No.7/25, Alagiripuram, 1st Street, Bharadeeswarar Colony, Ko dambakkam, Chennai, Kodambakkam, Chennai City Corporation, Chennai, Tamil Nadu.
Other Info - ADR0110
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