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compositionComposition:ACECLOFENAC-100MG+SERRATIOPEPTIDASE-15MG
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Prescription Medicine
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Aece-S Tablet is used to relieve pain. It contains Aceclofenac and Serratiopeptidase which work by blocking the release of chemical messengers that cause pain and preventing swelling. In some cases, this medicine may cause side effects such as nausea, vomiting, loss of appetite, heartburn, stomach pain, indigestion, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ACECLOFENAC-100MG+SERRATIOPEPTIDASE-15MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Aece-S Tablet

Aece-S Tablet is an oral medication commonly prescribed to relieve pain, inflammation, and swelling associated with muscle, joint, or bone conditions. It is designed to help individuals recover from painful inflammatory states, such as those following surgeries, injuries, or chronic joint conditions. This medication helps restore comfort so you can return to your regular daily activities.

To get the best results, you should take this medicine consistently at the times prescribed by your doctor. It is highly recommended to take Aece-S Tablet with or immediately after food to help protect your stomach from irritation. Additionally, incorporating gentle physical movements and staying well-hydrated can support your recovery process during treatment.

While taking Aece-S Tablet, some people may experience mild side effects like nausea, mild stomach discomfort, or dizziness. However, you must seek medical attention immediately if you notice severe signs, such as sharp stomach pain, black stools, or an unexpected skin rash. Always consult your doctor if you experience any unusual symptoms that do not go away.

Do not take this if you have a history of active stomach ulcers, severe heart failure, or serious kidney or liver issues. It is important to talk to your doctor before starting Aece-S Tablet if you have asthma, high blood pressure, or a history of bleeding disorders. Your doctor will help determine if this medication is safe for your specific health profile.

This medicine can interact with other treatments, including blood thinners and other painkillers, which may increase the risk of stomach bleeding. You should also avoid drinking alcohol while on this medication. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before starting treatment.

Uses of Aece-S Tablet

Aece-S Tablet is used to relieve pain, inflammation, and swelling associated with muscle, joint, or bone conditions. The detailed uses of Aece-S Tablet are as follows:

  • Rheumatoid arthritis: Helps reduce painful joint inflammation, stiffness, and swelling associated with this chronic autoimmune condition.
  • Osteoarthritis: Alleviates wear-and-tear joint pain, helping to improve physical movement and flexibility.
  • Ankylosing spondylitis: Relieves severe spinal pain and stiffness, allowing for more comfortable daily movement.
  • Post-operative pain: Manages localised pain and reduces tissue swelling following surgical procedures.
  • Dental pain: Controls severe toothaches and reduces gum inflammation after dental surgeries or extractions.
     

Key Benefits

Aece-S Tablet helps relieve pain and reduce inflammation associated with musculoskeletal injuries and inflammatory conditions. By reducing swelling and discomfort, it supports faster recovery and improves physical mobility.

  • Helps Relieve Pain and Inflammation: By reducing pain and swelling at the affected area, Aece-S Tablet helps improve comfort and makes everyday movements easier.
  • Supports Faster Recovery: By controlling inflammation and reducing tissue swelling, Aece-S Tablet promotes the natural healing of injured muscles, joints, and soft tissues.
  • Improves Mobility and Physical Function: As pain and swelling decrease, Aece-S Tablet helps restore flexibility and range of motion, allowing you to participate more comfortably in physical therapy and daily activities.
     
Side effects of Aece-S Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Aece-S Tablet should be taken with food, to reduce the chances of stomach upset.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Aece-S Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Aece-S Tablet Works

Aece-S Tablet is a combination medication containing two active components that work together to relieve pain and reduce swelling. The first component, aceclofenac, is a pain-relieving medicine that stops the body from releasing specific chemical messengers, known as prostaglandins, which cause pain, redness, and inflammation at the affected site. The second component, serratiopeptidase, is a specialised enzyme that targets the physical swelling directly. It works by breaking down abnormal proteins that accumulate at the site of injury or inflammation. This thins out excess fluids, promotes proper drainage, and allows the tissue to heal more rapidly. Together, these two actions provide highly effective, synchronised relief.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Aece-S Tablet to avoid unpleasant side-effects like increased risk of stomach bleeding.

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Pregnancy

Unsafe

The use of Aece-S Tablet may impair female fertility and is not recommended in pregnant women or those planning for pregnancy.

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Breast Feeding

Unsafe

Aece-S Tablet contains serratiopeptidase, which may pass into the breast milk. So, it is not recommended for nursing mothers.

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Driving

Unsafe

Aece-S Tablet may affect driving as it causes dizziness. So do not drive a motor vehicle or operate heavy machinery after taking Aece-S Tablet.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Aece-S Tablet should not be given to children as the safety and effectiveness were not established.

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Heart

Unsafe

Aece-S Tablet is not recommended in cardiac patients due to its adverse effects. However, if prescribed, extreme caution should be exercised.

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Geriatrics

Caution

Aece-S Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Aece-S Tablet

If you suspect an accidental overdose, seek immediate medical care or contact your local emergency health service. Do not wait for severe symptoms to develop before seeking professional help.

Diet & Lifestyle Advise

  • Eat stomach-friendly meals: Avoid highly spicy, greasy, or acidic foods while taking this medication, as they can worsen potential stomach irritation.
  • Maintain proper hydration: Drink plenty of water throughout the day to support your kidneys as they process and clear the medication.
  • Follow an anti-inflammatory diet: Incorporate foods rich in antioxidants and omega-3 fatty acids, such as leafy greens, berries, and nuts, to support natural joint health.
  • Apply temperature compresses: Use cold packs to reduce acute swelling, or warm compresses to ease chronic muscle and joint stiffness.
  • Avoid strenuous activities: Rest the injured area and engage only in gentle, low-impact movements like stretching or walking to maintain joint flexibility without causing further strain.
     
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How Soon It Starts Working

The time required for Aece-S Tablet to start to work: Aece-S Tablet shows its action within 1 to 2 hours of intake. The time for which the effects of Aece-S Tablet last: Aece-S Tablet effect lasts for 10 to 12 hours.

What if you forget to take Aece-S Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Aece-S Tablet tablets at controlled room temperature, safely between 15°C and 30°C (59°F to 86°F). •Keep the medication inside its original packaging to protect the tablets from direct light and moisture.

Drug Warnings

  • Always inspect the packaging before use; do not take the medication if the blister foil is torn, damaged, or if the tablets show discolouration.
  • Do not consume alcohol while taking Aece-S Tablet, as it significantly increases your risk of severe stomach ulcers and internal bleeding.
  • Avoid taking other non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin at the same time unless your doctor explicitly tells you to do so.
  • Inform your dentist or surgeon that you are taking Aece-S Tablet prior to any planned procedures, as this medication can affect blood clotting.
  • Monitor your blood pressure regularly while taking this medication, especially if you have a history of hypertension, as it can occasionally cause mild fluid retention.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (such as warfarin): May significantly increase the risk of severe bleeding.
  • Other pain medications (NSAIDs or corticosteroids): Can raise the risk of stomach irritation, pain, and bleeding ulcers.
  • Blood pressure medications: The effectiveness of your blood pressure treatment may be reduced when taken with this medicine.
  • Lithium or methotrexate: Aece-S Tablet may increase the levels of these substances in your body, potentially leading to toxic side effects.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Combining alcohol with this medication severely increases the risk of stomach irritation, ulcers, and potential liver damage.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Aece-S Tablet is used to relieve post-traumatic pain, low back pain, cervical pain, and pain associated with spondylitis, osteoarthritis, and rheumatoid arthritis.
Aece-S Tablet is a combination of two medicines that include aceclofenac and serratiopeptidase. Aece-S Tablet contains ‘aceclofenac’ which works by blocking the release of a chemical messenger called prostaglandin, produced by COX-2 in the brain, responsible for pain, swelling, and inflammation. On the other hand, Aece-S Tablet contains serratiopeptidase, which reduces swelling and inflammation through proteins' breakdown. Thus Aece-S Tablet helps to relieve musculoskeletal pain and in various joints conditions.
Do not take Aece-S Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Do not exceed the dose and duration of treatment as prescribed by the doctor.
Diarrhea might be a side-effect of Aece-S Tablet. Drink enough fluids and eat fiber-rich food if you experience diarrhea. If you find blood in stools (tarry stools) or if you experience excess diarrhea consult your doctor. Do not take anti-diarrheal medicine on your own.
Ankylosing spondylitis is arthritis of the spine that can lead to the vertebrae's fusion, leading to pain and inflammation in the spine (vertebrae).
Avoid or limit consumption of alcohol with Aece-S Tablet as it increases the chances of stomach ulcers and bleeding. It may also lead to increased dizziness and drowsiness.
The most common side effects of Aece-S Tablet are nausea, vomiting, loss of appetite (feeling not hungry), heartburn, stomach pain, indigestion, diarrhea. Most of these side effects of Aece-S Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Serrapeptase is a proteolytic enzyme (protein breaking) derived from silkworms used to treat inflammation and pain following surgery, joint pain, dental surgery and other medical purposes.
No, Aece-S Tablet is not addictive. It is not a habit-forming medication.
Yes, Aece-S Tablet may provide relief from toothache due to infection, damage to the tooth nerve, extraction or injury. Aece-S Tablet reduces pain and inflammation by inhibiting the production of substances in the body that cause pain and inflammation.
No, you should avoid taking Aece-S Tablet on an empty stomach. Taking it with or immediately after food helps protect your stomach lining from irritation and indigestion. Talk to your doctor if you experience persistent stomach discomfort.
Aece-S Tablet is generally not recommended for use during pregnancy, especially in the third trimester, as it may affect the baby’s development or cause complications during delivery. Talk to your doctor to discuss safer alternatives for pain management.
Some people may experience mild dizziness or sleepiness while taking this medication. If you feel dizzy or less alert, avoid driving, cycling, or operating machinery. Talk to your doctor if these symptoms affect your daily life.
Taking Aece-S Tablet with aspirin increases the risk of severe stomach bleeding and ulcers. You should avoid this combination unless your doctor has specifically instructed you to take both. Talk to your doctor for personalised advice.
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your normal routine. Do not take a double dose. Talk to your doctor or pharmacist if you are unsure.
Yes, in some cases, Aece-S Tablet can cause mild fluid retention, which may raise your blood pressure. If you have hypertension, monitor your blood pressure closely. Talk to your doctor if you notice any sudden increases.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.4240 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Aceclofenac 100Mgs Leaflet Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Serrapeptase Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. ScienceDirect Topics. S181808761630160X - Research & Medical Applications Summary. Amsterdam, Netherlands: Elsevier; 2025. [Accessed on 02 Jun. 2026]Check here
  5. PubChem PubChem. [Accessed on 02 Apr. 2019]Check here
  6. Manju Tiwari. The role of serratiopeptidase in the resolution of inflammation. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in May 2017] [Accessed on 3rd July 2024]Check here
  7. Ciplamed. MOVEXX SP Tablets [Revised in September 2023] [Accessed on 3rd July 2024]Check here

Country of origin

India
Other Info - AE23032
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