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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
AF-50 Tablet is used to treat a broad range of infections caused due to fungi and yeast. It contains Fluconazole, which kills or prevents the growth of fungi or yeast. It may cause common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

FLUCONAZOLE-50MG

Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About AF-50 Tablet

AF-50 Tablet is an antifungal medicine that is used to treat a broad range of infections caused due to fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood.

AF-50 Tablet contains ‘Fluconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, which interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed, or their growth is minimized.

Take this medicine as prescribed by your doctor. AF-50 Tablet has common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to AF-50 Tablet or any of its components. Let your doctor know if you have any liver, kidney or heart problems before starting AF-50 Tablet. Pregnant and breastfeeding women should consult their doctor before starting AF-50 Tablet. It is advised to avoid alcohol intake while using AF-50 Tablet to prevent any undesirable effects.

Uses of AF-50 Tablet

Treatment of Fungal infections.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

AF-50 Tablet works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. It is used to treat various fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), oesophagal candidiasis (candida esophagitis), candida infections (urinary tract infections, peritonitis), and cryptococcal meningitis. Besides this, AF-50 Tablet is also used to prevent candidiasis and coccidioidomycosis in patients who receive cancer or radiation treatment while undergoing bone marrow transplantation. AF-50 Tablet is effective in treating soft tissue and pulmonary infections when compared to other azole antifungal drugs.

How AF-50 Tablet Works

AF-50 Tablet contains ‘Fluconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, which interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed, or their growth is minimized.

Storage

Store in a cool and dry place away from sunlight
Side effects of AF-50 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Divide daily food intake into smaller, more frequent meals to ease stomach pressure and facilitate digestion.
  • Include fibre-rich foods like fruits, vegetables, and whole grains to promote regular bowel movements and support gut health.
  • During severe stomach pain episodes, opt for easily digestible foods such as rice, toast, bananas, and applesauce.
  • Identify and limit foods that exacerbate symptoms, including spicy, greasy, caffeinated, acidic, and high-sugar foods.
  • Drink plenty of water throughout the day to help your digestion.
  • Properly chew food to break down particles and reduce stomach strain.
  • Participate in moderate exercise, such as walking or swimming, to enhance digestion and alleviate discomfort.
  • Avoid excessive alcohol and caffeine consumption, as they might irritate the stomach lining.
  • Avoid wearing tight clothing that may put strain on the abdomen.
  • Raise your head while sleeping to avoid acid reflux.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of AF-50 Tablet

Do not take more than the prescribed dose of AF-50 Tablet as it may cause overdose. The symptoms of overdose include mental/mood changes and hallucinations. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Please inform your doctor if you use any prescription, or non-prescription medicines, including vitamin and herbal supplements before using AF-50 Tablet. Do not use AF-50 Tablet if you are allergic to AF-50 Tablet or any of its components. Let your doctor know if you have any liver, kidney, or heart problems before starting AF-50 Tablet. This medicine may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels; however, please seek medical advice. Pregnant or lactating women should consult the doctor before taking the AF-50 Tablet. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with AF-50 Tablet to avoid undesirable effects 

Drug-Drug Interactions

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FluconazoleLomitapide
Critical
FluconazoleEliglustat
Critical

Drug-Drug Interactions

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FluconazoleLomitapide
Critical
How does the drug interact with AF-50 Tablet:
When Lomitapide is taken with AF-50 Tablet, may increase the blood levels of lomitapide.

How to manage the interaction:
Taking AF-50 Tablet with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleEliglustat
Critical
How does the drug interact with AF-50 Tablet:
When Eliglustat and AF-50 Tablet are taken together, AF-50 Tablet can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking AF-50 Tablet with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleErythromycin
Critical
How does the drug interact with AF-50 Tablet:
Taking AF-50 Tablet with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking AF-50 Tablet with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with AF-50 Tablet:
When Astemizole is taken with AF-50 Tablet, the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking AF-50 Tablet with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleDicoumarol
Severe
How does the drug interact with AF-50 Tablet:
Taking AF-50 Tablet with Dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction, AF-50 Tablet can be taken with Dicumarol if prescribed by the doctor. Consult the doctor if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue the medications without a doctor's advice.
FluconazoleFosphenytoin
Severe
How does the drug interact with AF-50 Tablet:
When Fosphenytoin is taken with AF-50 Tablet, may affect the Fosphenytoin levels in your body which can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of AF-50 Tablet with Fosphenytoin can possibly result in an interaction, but it can be taken if a doctor has advised it. Watch out for any signs of dizziness, fatigue, weakness, having trouble seeing, nausea, vomiting, or having trouble moving your muscles. If you notice any of these symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluconazoleSaquinavir
Severe
How does the drug interact with AF-50 Tablet:
Taking AF-50 Tablet with Saquinavir may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, AF-50 Tablet can be taken with Saquinavir if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.
FluconazoleColchicine
Severe
How does the drug interact with AF-50 Tablet:
Coadministration of colchicine with AF-50 Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Colchicine and AF-50 Tablet together may result in an interaction, they can be taken together if a doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting a doctor.
FluconazoleDolasetron
Severe
How does the drug interact with AF-50 Tablet:
Co-administration of Dolasetron taken with AF-50 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between AF-50 Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms - like an irregular heart rhythm, a heart condition, or prolonged diarrhea - it's best to call a doctor right away. Other symptoms to watch out for include sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
FluconazoleClopidogrel
Severe
How does the drug interact with AF-50 Tablet:
Co-administration of clopidogrel with AF-50 Tablet can reduce the effectiveness of clopidogrel.

How to manage the interaction:
Clopidogrel and AF-50 Tablet may interact, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid frequent douching to maintain the natural moisture in the vagina.

  • Use mild soap while taking baths and prefer warm baths.

  • Avoid harsh products on your skin.

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

  • Avoid or limit the intake of alcohol and caffeine.

  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcohol, and includes low-sugar fruits, non-starchy vegetables, and gluten-free foods.

  • A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

AF-50 Tablet Substitute

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Alcohol

Caution

It is advisable to avoid or limit the intake of alcohol while you use AF-50 Tablet.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or are planning to conceive before starting AF-50 Tablet.

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Breast Feeding

Caution

AF-50 Tablet should be used with caution and only under a doctor's advice if you are a lactating mother. Please seek medical advice for more information.

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Driving

Caution

AF-50 Tablet may sometimes cause dizziness or other side effects that may affect your mental ability to drive. Hence do not drive or operate machinery if you are not mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases when you are prescribed AF-50 Tablet.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases when you are prescribed AF-50 Tablet.

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Children

Caution

AF-50 Tablet may be prescribed to children by the doctor, depending on the infection. The doctor decides the right dose for a child based on his/her age and weight.

FAQs

AF-50 Tablet is used in the treatment of fungal infections.

AF-50 Tablet contains Fluconazole, an antifungal drug, which works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. Thus, it treats fungal infections.

Do not stop using AF-50 Tablet even if you feel better until the doctor's advised course is finished. Your symptoms may improve before the infection is completely cured.

The usual recommendation of dosage for AF-50 Tablet can be for a short time. However, your doctor may prescribe it for a longer time, depending on the type and severity of your infection.

AF-50 Tablet may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. However, it is advised to seek a doctor's advice before starting AF-50 Tablet if you have a previous medical history.

AF-50 Tablet is a prescription antifungal medication used to treat various fungal infections. Before taking AF-50 Tablet, you must consult a doctor to ensure it's the right medication for your condition and discuss any potential risks or interactions.

No, AF-50 Tablet is not typically used to treat cough, cold, or flu. It's an antifungal medication designed to treat fungal infections, not viral infections like the common cold or flu.

It's always best to follow your doctor's specific instructions regarding when to take Fluconazole. They can provide personalized advice based on your individual needs and medical history.

AF-50 Tablet has common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

AF-50 Tablet can interact with other drugs. Inform your healthcare practitioner of all medications you are taking, including over-the-counter medicines, prescription medications, and herbal supplements.

Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.

No, do not use AF-50 Tablet after the expiration date, as they may no longer be effective.

Dispose of unused medicines according to your local pharmacy's guidelines. Do not flush them down the toilet or pour them down the drain.

Certain herbal supplements may interact with AF-50 Tablet. It is important to inform your healthcare physician about all the supplements you use.

Country of origin

India

Manufacturer/Marketer address

Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - AF50001

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