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Drug-Drug Interactions
Drug-Drug Interactions
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Taking AFF Tablet with Posaconazole can increase the blood levels of AFF Tablet. This can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between posaconazole with AFF Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Co-administration of AFF Tablet with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.
How to manage the interaction:
Although there is a possible interaction between AFF Tablet and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
Coadministration of AFF Tablet and Fluorouracil may increase the effects of Fluorouracil and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.
How to manage the interaction:
Although there is a possible interaction between AFF Tablet and Fluorouracil, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.
Trimethoprim may decrease the blood levels and effects of AFF Tablet.
How to manage the interaction:
Although there is a possible interaction between AFF Tablet and Trimethoprim, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
Sulfadiazine may decrease the blood levels and effects of AFF Tablet.
How to manage the interaction:
Although there is a possible interaction between AFF Tablet and Sulfadiazine, you can take these medicines together if prescribed by your doctor.
Coadministration of AFF Tablet and Cholestyramine may interfere with the absorption of AFF Tablet.
How to manage the interaction:
Although taking Cholestyramine and AFF Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
Coadministration of AFF Tablet and Carbamazepine may reduce the blood levels of AFF Tablet.
How to manage the interaction:
Although there is a possible interaction between AFF Tablet and Carbamazepine, you can take these medicines together if prescribed by your doctor. However, if your condition changes or you experience loss of seizure control, contact your doctor.
Using AFF Tablet together with fosamprenavir may significantly increase the blood levels of AFF Tablet.
How to manage the interaction:
Although there is a possible interaction between AFF Tablet and Fosamprenavir, you can take these medicines together if prescribed by a doctor. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
Taking AFF Tablet with indinavir may considerably raise AFF Tablet levels in the blood.
How to manage the interaction:
Taking AFF Tablet and indinavir together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
When AFF Tablet and leflunomide are taken together it can increase the risk of liver problems.
How to manage the interaction:
Although taking AFF Tablet and leflunomide together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
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AFF Tablet Substitute
Alcohol
Caution
Avoid drinking alcohol while taking AFF Tablet . It can raise triglyceride levels and may increase your risk of liver damage.
Pregnancy
Caution
Please consult your doctor. There are no well-controlled studies on the effects of AFF Tablet in pregnancy. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
Caution
There is no substantial research yet on the use of AFF Tablet in breastfeeding/nursing mothers. Tell your doctor if you are a nursing mother before taking AFF Tablet ; your doctor will decide whether AFF Tablet can be taken by breastfeeding mothers.
Driving
Not applicable
AFF Tablet usually does not affect your ability to drive or operate machinery. However, do not drive or operate machinery if you feel sleepy or dizzy after taking your medicine.
Liver
Safe if prescribed
Inform your doctor before taking AFF Tablet if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Safe if prescribed
Inform your doctor before taking AFF Tablet if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Safe if prescribed
There was limited information about the usage of AFF Tablet in paediatric patients. Please seek medical advice.
Heart
AFF Tablet is often prescribed to patients with heart problems to manage high cholesterol and reduce cardiovascular risk. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.
Geriatrics
Caution
Geriatric patients may take AFF Tablet under medical supervision. Age-related liver, kidney, or muscle sensitivity requires regular monitoring and possible dose adjustments.
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