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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Afogatran 110 Capsule is used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It contains Dabigatran, which works by inhibiting the production of clotting factors and prevents blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. It may cause side effects such as bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

DABIGATRAN-110MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Afogatran 110 Capsule

Afogatran 110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.

Afogatran 110 Capsule contains ‘Dabigatran’, which works by inhibiting the production of clotting factors Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Afogatran 110 Capsule helps prevent blood clots if you have an increased risk of having a heart attack, or stroke.

Take Afogatran 110 Capsule as prescribed by your doctor. You are advised to take Afogatran 110 Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), and nausea, stomach pain, indigestion. Most of these side effects of Afogatran 110 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Afogatran 110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 110 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 110 Capsule . Try not to stop taking this medicine of your own. Stopping a sudden intake of Afogatran 110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke.

Uses of Afogatran 110 Capsule

Prevention of stroke, Prevention of heart attack.

Directions for Use

Swallow Afogatran 110 Capsule as a whole with water; do not crush or chew it.

Medicinal Benefits

Afogatran 110 Capsule belongs to a class of drugs known as anticoagulants or blood thinner. It prevents clot formation in the deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain), and heart in patients with atrial fibrillation (irregular heart rhythm). Afogatran 110 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Afogatran 110 Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

How Afogatran 110 Capsule Works

Afogatran 110 Capsule contains ‘Dabigatran’, which works by inhibiting the production of clotting factors Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Afogatran 110 Capsule helps prevent blood clots if you have an increased risk of having a heart attack, or stroke.

Storage

Store in a cool and dry place away from sunlight
Side effects of Afogatran 110 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • You can take your medicine with meals to lower the chances of getting stomach pain.
  • Avoid foods that are acidic, spicy, sugary, or greasy.
  • Eat foods that are easily digestible such as rice, toast, and bananas.
  • Eat your meals in smaller amounts throughout the day to prevent strain on your stomach and digestion.
  • Drink water or fluids to stay hydrated and prevent stomach upset.
  • Use a heating pad or massage your stomach area.
  • Engage in mild physical activities such as yoga and walking.

What if I have taken an overdose of Afogatran 110 Capsule

Do not take more than the prescribed dose of Afogatran 110 Capsule as it may cause overdose leading to excessive bleeding. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Afogatran 110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 110 Capsule . Safety and effectiveness of Afogatran 110 Capsule have not been established, so its use should be avoided in pediatric patients or children less than 18 years of age. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 110 Capsule . Try not to stop taking Afogatran 110 Capsule of your own. Stopping a sudden intake of Afogatran 110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Hence, you should consult a doctor before stopping the dose of Afogatran 110 Capsule . You should inform the doctor that you are taking Afogatran 110 Capsule before any surgery is scheduled. Afogatran 110 Capsule can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Avoid consumption of alcohol while taking Afogatran 110 Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Afogatran 110 Capsule:
When Mifepristone is taken with Afogatran 110 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Afogatran 110 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
How does the drug interact with Afogatran 110 Capsule:
Using dabigatran together with dalteparin may increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Afogatran 110 Capsule may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Afogatran 110 Capsule:
Coadministration of Warfarin with Afogatran 110 Capsule can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Afogatran 110 Capsule and warfarin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Afogatran 110 Capsule:
Coadministration of Piroxicam with Afogatran 110 Capsule can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Piroxicam and Afogatran 110 Capsule, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with carbamazepine may significantly reduce the blood levels of dabigatran, which may make the medication less effective.

How to manage the interaction:
Although taking carbamazepine and Afogatran 110 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Afogatran 110 Capsule:
Concomitant use of diclofenac with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking diclofenac with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Afogatran 110 Capsule:
Using dabigatran together with ketorolac may increase the risk of bleeding.

How to manage the interaction:
Although taking Ketorolac and Afogatran 110 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor.
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Urokinase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Afogatran 110 Capsule with Urokinase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Bivalirudin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Afogatran 110 Capsule with Bivalirudin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Regorafenib can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Afogatran 110 Capsule with Regorafenib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DABIGATRAN-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Afogatran 110 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Afogatran 110 Capsule treatment.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Afogatran 110 Capsule .

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Afogatran 110 Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Afogatran 110 Capsule is unsafe to use during pregnancy since it affects the foetus. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Afogatran 110 Capsule .

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Breast Feeding

Caution

There is limited data on how Afogatran 110 Capsule affects breastfeeding. However, it is unsafe to use Afogatran 110 Capsule if you are lactating, since it passes through the breast milk and harm the baby. Please consult your doctor before starting Afogatran 110 Capsule .

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Driving

Caution

Afogatran 110 Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 110 Capsule . However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 110 Capsule . However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Afogatran 110 Capsule is not recommended for children below the age of 18 years. The safety and efficacy of Afogatran 110 Capsule have not been established in children.

Have a query?

FAQs

Afogatran 110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation.

Please consult your doctor if Afogatran 110 Capsule needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Afogatran 110 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery. It also causes a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural). This type of blood clot could cause long-term paralysis.

Afogatran 110 Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. It is advisable, please consult your doctor and take Afogatran 110 Capsule for as long as your doctor has prescribed it.

Taking Afogatran 110 Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Afogatran 110 Capsule .

Afogatran 110 Capsule consists of Dabigatran is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

No, you are not recommended to stop taking Afogatran 110 Capsule without consulting your doctor to worsen the condition. Therefore, take Afogatran 110 Capsule for as long as your doctor has prescribed it.

Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.

You can take Afogatran 110 Capsule with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.

Take Afogatran 110 Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take Afogatran 110 Capsule as long as your doctor has prescribed it for you.

You are recommended to avoid consumption of alcohol with Afogatran 110 Capsule as it may increase the risk of bleeding.

Hair loss is not a known side effect of Afogatran 110 Capsule . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor guide you on how to cope with this situation.

It varies from person to person and depends on the conditions that we treat.

Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 110 Capsule . However, it is not recommended in patients with severe liver diseases.

Store in a cool and dry place away from sunlight. Keep Afogatran 110 Capsule out of the sight and reach of children.

Yes, bleeding is the main risk associated with Afogatran 110 Capsule treatment; patients should be monitored for signs of bleeding.

Afogatran 110 Capsule is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 110 Capsule .

Common side effects of Afogatran 110 Capsule may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - AFO0014

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