Afogatran 110 Capsule 10's
MRP ₹339.5
(Inclusive of all Taxes)
₹50.9 Cashback (15%)
Extra 15% Off with Bank Offers
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Genuine Products
Composition :
DABIGATRAN-110MG
Manufacturer/Marketer :
Torrent Pharmaceuticals Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
About Afogatran 110 Capsule
Afogatran 110 Capsule is used to prevent blood clot formation and prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm). It is also used to prevent deep vein thrombosis (blood clots in the leg veins) and pulmonary embolism (blood clots in the lung).
Afogatran 110 Capsule contains ‘Dabigatran’, which works by inhibiting the production of clotting factor Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation.
In some cases, Afogatran 110 Capsule may cause certain common side effects such as bleeding, anaemia, nausea, stomach pain, and indigestion. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.
If you are known to be allergic to Afogatran 110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 110 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or a history of bleeding, inform your doctor before taking Afogatran 110 Capsule .
Uses of Afogatran 110 Capsule
Afogatran 110 Capsule is used to prevent and treat blood clots. The detailed uses of Afogatran 110 Capsule are as follows:
- Prevention of stroke and blood clots in atrial fibrillation: Afogatran 110 Capsule is used in patients with non-valvular atrial fibrillation to lower the risk of stroke and blood clots.
- Treatment of Deep Vein Thrombosis (DVT): Afogatran 110 Capsule is used to treat blood clots in deep veins, usually in the legs, to prevent them from growing or breaking off.
- Treatment of Pulmonary Embolism (PE):Afogatran 110 Capsule is prescribed to treat blood clots in the lungs, helping restore normal blood flow and prevent recurrence.
- Prevention of Recurrent DVT and PE: Afogatran 110 Capsule is used to prevent future episodes of DVT and PE in patients with a history of clotting disorders.
- Prevention of Venous Thromboembolism (VTE) After Orthopaedic Surgery: Afogatran 110 Capsule is used after hip or knee replacement surgery to prevent the formation of blood clots due to immobility.
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Directions for Use
- Afogatran 110 Capsule can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow Afogatran 110 Capsule as a whole with a glass of water.
- Do not chew, crush, or break it.
Medicinal Benefits
- Afogatran 110 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation.
- Afogatran 110 Capsule prevents clot formation in the deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain), and heart in patients with atrial fibrillation (irregular heart rhythm).
- It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.
- Afogatran 110 Capsule works by stopping the action of the clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.
- It helps your blood flow more easily, lowering the chance of dangerous clots forming.
How Afogatran 110 Capsule Works
Afogatran 110 Capsule contains Dabigatran, which works by inhibiting the production of clotting factor Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Afogatran 110 Capsule helps prevent blood clots if you have an increased risk of having a heart attack or stroke.
Storage
• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Afogatran 110 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
- Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
- Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
- Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
- Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
- Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
- Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
- Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Avoid other medicines that increase the risk of bleeding.
- Use an electric razor and a soft-bristled toothbrush.
- Monitor for signs of bleeding like bleeding gums, unusual bruising, blood in stool, nosebleeds, or heavy menstrual bleeding.
- If you experience severe bleeding, apply direct pressure on the wound and consult a doctor promptly.
- If the risk of bleeding is high, discuss with your doctor about possibility of switching to different medicine with a lower bleeding risk.
Here are the precise steps to cope with diarrhoea caused by medication usage:
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
What if I have taken an overdose of Afogatran 110 Capsule
Do not take more than the prescribed dose of Afogatran 110 Capsule as it may cause serious side effects leading to excessive bleeding. If you suspect you have taken an overdose, seek immediate medical attention.
Drug Warnings
- If you are known to be allergic to Afogatran 110 Capsule or any other medicines, please tell your doctor.
- You should inform the doctor that you are taking Afogatran 110 Capsule before any surgery is scheduled.
- Afogatran 110 Capsule can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural).
- Do not stop taking Afogatran 110 Capsule of your own. Stopping a sudden intake of Afogatran 110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Hence, you should consult a doctor before stopping the dose of Afogatran 110 Capsule .
- If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 110 Capsule .
- If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 110 Capsule .
- Safety and effectiveness of Afogatran 110 Capsule have not been established, so its use should be avoided in pediatric patients or children less than 18 years of age.
- Avoid consumption of alcohol while taking Afogatran 110 Capsule as it may increase the risk of stomach bleeding.
Drug-Drug Interactions
Critical
Dabigatran etexilateFosphenytoin
Severe
Drug-Drug Interactions
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Critical
How does the drug interact with Afogatran 110 Capsule:
When Mifepristone is taken with Afogatran 110 Capsule, it may increase the risk of severe vaginal bleeding in women.
How to manage the interaction:
Taking Mifepristone with Afogatran 110 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
When Mifepristone is taken with Afogatran 110 Capsule, it may increase the risk of severe vaginal bleeding in women.
How to manage the interaction:
Taking Mifepristone with Afogatran 110 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateFosphenytoin
Severe
How does the drug interact with Afogatran 110 Capsule:
When Afogatran 110 Capsule is taken with Fosphenytoin, it can lower the rate at which the body breaks down Afogatran 110 Capsule. This can lead to low treatment outcomes.
How to manage the interaction:
Taking Fosphenytoin with Afogatran 110 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like sudden breathlessness, sharp chest pain, throbbing, cramping pain, swelling, redness or warmth in legs or arms, it's important to let your doctor know right away. They can recommend other options that won't cause any problems with your current medications. Do not discontinue any medications without first consulting your doctor.
When Afogatran 110 Capsule is taken with Fosphenytoin, it can lower the rate at which the body breaks down Afogatran 110 Capsule. This can lead to low treatment outcomes.
How to manage the interaction:
Taking Fosphenytoin with Afogatran 110 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like sudden breathlessness, sharp chest pain, throbbing, cramping pain, swelling, redness or warmth in legs or arms, it's important to let your doctor know right away. They can recommend other options that won't cause any problems with your current medications. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Afogatran 110 Capsule:
Coadministration of Naproxen and Afogatran 110 Capsule may increase the risk or severity of unusual bleeding problems.
How to manage the interaction:
Taking Naproxen and Dabigatran together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Coadministration of Naproxen and Afogatran 110 Capsule may increase the risk or severity of unusual bleeding problems.
How to manage the interaction:
Taking Naproxen and Dabigatran together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Ramucirumab can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Afogatran 110 Capsule with Ramucirumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Taking Afogatran 110 Capsule with Ramucirumab can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Afogatran 110 Capsule with Ramucirumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Afogatran 110 Capsule:
Taking ticagrelor with Afogatran 110 Capsule may increase the risk of bleeding.
How to manage the interaction:
Although taking Afogatran 110 Capsule with Ticagrelor together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact your doctor immediately. Do not stop using any medications without consulting your doctor.
Taking ticagrelor with Afogatran 110 Capsule may increase the risk of bleeding.
How to manage the interaction:
Although taking Afogatran 110 Capsule with Ticagrelor together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact your doctor immediately. Do not stop using any medications without consulting your doctor.
How does the drug interact with Afogatran 110 Capsule:
Co-administration of Afogatran 110 Capsule and Rivaroxaban can increase the risk of bleeding, including severe blood loss.
How to manage the interaction:
Co-administration of Afogatran 110 Capsule and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding, dizziness, tarry stools, coughing up or vomiting blood, or severe headache, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Afogatran 110 Capsule and Rivaroxaban can increase the risk of bleeding, including severe blood loss.
How to manage the interaction:
Co-administration of Afogatran 110 Capsule and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding, dizziness, tarry stools, coughing up or vomiting blood, or severe headache, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Dabigatran etexilatePhenylbutazone
Severe
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Phenylbutazone can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Afogatran 110 Capsule with Phenylbutazone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Taking Afogatran 110 Capsule with Phenylbutazone can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Afogatran 110 Capsule with Phenylbutazone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with carbamazepine may significantly reduce the blood levels of dabigatran, which may make the medication less effective.
How to manage the interaction:
Although taking carbamazepine and Afogatran 110 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Taking Afogatran 110 Capsule with carbamazepine may significantly reduce the blood levels of dabigatran, which may make the medication less effective.
How to manage the interaction:
Although taking carbamazepine and Afogatran 110 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Bivalirudin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Afogatran 110 Capsule with Bivalirudin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Taking Afogatran 110 Capsule with Bivalirudin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Afogatran 110 Capsule with Bivalirudin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Alteplase can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Afogatran 110 Capsule with Alteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Taking Afogatran 110 Capsule with Alteplase can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Afogatran 110 Capsule with Alteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
DABIGATRAN-110MGHerbal products/medicines
Drug-Food Interactions
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DABIGATRAN-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill
How to manage the interaction:
Herbs and supplements may interact with Afogatran 110 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Afogatran 110 Capsule treatment.
St. John’S Wort, Garlic Pill
How to manage the interaction:
Herbs and supplements may interact with Afogatran 110 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Afogatran 110 Capsule treatment.
Diet & Lifestyle Advise
- Keep your cholesterol and triglyceride levels under control.
- Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.
- Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
- Keep a check on your weight and exercise regularly to keep your heart healthy.
- Your doctor also guides you on how to notice and manage the early symptoms of heart disease.
Habit Forming
No
Therapeutic Class
ANTICOAGULANT/ANTITHROMBOTIC
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Alcohol
Unsafe
You are recommended to avoid consumption of alcohol with Afogatran 110 Capsule as it may increase the risk of bleeding.
Pregnancy
Consult your doctor
Afogatran 110 Capsule is unsafe to use during pregnancy since it affects the foetus. Please talk to your doctor if you are planning to become pregnant or already pregnant before starting Afogatran 110 Capsule .
Breast Feeding
Consult your doctor
There is limited data on how Afogatran 110 Capsule affects breastfeeding. However, it is unsafe to use Afogatran 110 Capsule if you are lactating, since it passes through the breast milk and harm the baby. Please consult your doctor before starting Afogatran 110 Capsule .
Driving
Consult your doctor
Afogatran 110 Capsule usually does not affect your ability to drive or operate machinery. Consult your doctor if you have any concerns.
Liver
Consult your doctor
Let your doctor know if you have any history of liver diseases or hepatic impairment.
Kidney
Consult your doctor
Let your doctor know if you have any history of kidney diseases.However, it is not recommended in patients with severe kidney diseases.
Children
Unsafe
Afogatran 110 Capsule is not recommended for children below the age of 18 years. The safety and efficacy of Afogatran 110 Capsule have not been established in children.
Heart
Caution
Afogatran 110 Capsule should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Afogatran 110 Capsule .
Geriatrics
Caution
Afogatran 110 Capsule should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Afogatran 110 Capsule .
FAQs
Country of origin
India
Manufacturer/Marketer address
Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - AFO0014
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