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Afogatran 150 Capsule 10's

Afogatran 150 Capsule 10's

Prescription drug
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Manufacturer/Marketer

TORRENT PHARMA LTD

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

About Afogatran 150 Capsule 10's

Afogatran 150 Capsule 10's belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), and to reduce the risk of clots in people who have undergone knee or hip replacement surgeries. 

Afogatran 150 Capsule 10's contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Afogatran 150 Capsule 10's helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Take Afogatran 150 Capsule 10's as prescribed by your doctor. You are advised to take Afogatran 150 Capsule 10's for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects of Afogatran 150 Capsule 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Afogatran 150 Capsule 10's or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 150 Capsule 10's. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 150 Capsule 10's. Try not to stop taking this medicine on your own. Discontinuing Afogatran 150 Capsule 10's may worsen your condition and increase the risk of heart attack, and stroke.

Uses of Afogatran 150 Capsule 10's

Prevention of blood clot formation, deep vein thrombosis, and pulmonary embolism

Medicinal Benefits

Afogatran 150 Capsule 10's belongs to a class of drugs known as anticoagulants or blood thinners. Afogatran 150 Capsule 10's is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Afogatran 150 Capsule 10's works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Directions for Use

Take Afogatran 150 Capsule 10's exactly as your doctor has prescribed it. Swallow it as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Afogatran 150 Capsule 10's

  • Stomach pain
  • Vomiting
  • Bleeding
  • Anaemia (low number of red blood cells)
  • Nausea
  • Diarrhoea

Drug Warnings

If you are known to be allergic to Afogatran 150 Capsule 10's or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 150 Capsule 10's. Afogatran 150 Capsule 10's is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 150 Capsule 10's. You should inform the doctor that you are taking Afogatran 150 Capsule 10's if you are due to undergo surgery. Avoid consumption of alcohol while taking Afogatran 150 Capsule 10's as it may increase the risk of stomach bleeding.

Drug Interactions

Drug-Drug Interactions: Afogatran 150 Capsule 10's may interact with medicines to reduce blood clotting (warfarin, phenprocoumon, acenocoumarol, heparin, clopidogrel, prasugrel, ticagrelor, rivaroxaban), medicines to treat abnormal heartbeats  (amiodarone, dronedarone, quinidine, verapamil), medicines to treat fungal infections (ketoconazole, itraconazole), medicines to prevent organ rejection after transplantation (tacrolimus, cyclosporine) antiviral or HIV medicines (ritonavir, glecaprevir, pibrentasvir), antibiotics (rifampicin, clarithromycin), pain reliever (aspirin, ibuprofen, diclofenac), antiepileptic drugs (carbamazepine, phenytoin).

Drug-Food Interactions: Afogatran 150 Capsule 10's may interact with St. John’s wort, herbal medicine for depression.

Drug-Disease Interactions: Afogatran 150 Capsule 10's should be used with caution in patients with kidney, liver, or bleeding problems, heart problems, and unstable blood pressure.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENPROCOUMON
  • ACENOCOUMAROL
  • HEPARIN
  • CLOPIDOGREL
  • PRASUGREL
  • TICAGRELOR
  • RIVAROXABAN
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • VERAPAMIL
  • ITRACONAZOLE
  • KETOCONAZOLE
  • TACROLIMUS
  • CYCLOSPORINE
  • INDINAVIR
  • RITONAVIR
  • RIFAMPICIN
  • CLARITHROMYCIN
  • GLECAPREVIR
  • PIBRENTASVIR
  • IBUPROFEN
  • DICLOFENAC
  • PHENYTOIN
  • CARBAMAZEPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.

Special Advise

  • You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalized ratio) to analyze your blood clotting time.
  • In case you miss a dose of Afogatran 150 Capsule 10's, take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.

Disease/Condition Glossary

Thrombosis/Blood Clot: A blood clot can occur in any part of the body and can lead to a heart attack, stroke, or damage to organs. Blood clots can reach the arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. 

Deep vein thrombosis (blood clots in legs): It is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling. 

Pulmonary embolism (blood clots in the lung): It is a chronic condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.

Stroke (blood clots in the brain): It occurs when the supply of blood to part of your brain is stopped or reduced. This prevents brain tissue from getting nutrients and oxygen leading to the death of brain cells.

Heart attack: A heart attack means the death of heart tissue due to a shortage of blood supply to the heart muscles. This can occur when there is an accumulation of cholesterol or fat narrowing the heart's major veins or when other substances like a blood clot are blocking the flow of blood. 

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Afogatran 150 Capsule 10's as it may increase the risk of bleeding.

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Pregnancy

Caution

Please consult your doctor if you are planning to become pregnant or already pregnant before starting Afogatran 150 Capsule 10's. Your doctor will prescribe Afogatran 150 Capsule 10's only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Afogatran 150 Capsule 10's. Consult your doctor if you have nay concerns.

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Driving

Safe if prescribed

Afogatran 150 Capsule 10's usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 150 Capsule 10's. However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 150 Capsule 10's. However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Afogatran 150 Capsule 10's is not recommended for children below the age of 18 years as the safety and efficacy of Afogatran 150 Capsule 10's have not been established in children.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info -

FAQs

Afogatran 150 Capsule 10's is a thrombin inhibitor. The inhibition of thrombin, reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.
No, you are not recommended to stop taking Afogatran 150 Capsule 10's without consulting your doctor as it may worsen the condition. Therefore, take Afogatran 150 Capsule 10's for as long as your doctor has prescribed it.
Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Afogatran 150 Capsule 10's a few days before surgery since it can cause an increased risk of bleeding during surgery.
Taking Afogatran 150 Capsule 10's during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Afogatran 150 Capsule 10's.
Afogatran 150 Capsule 10's may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

Author Details

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