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  1. Home
  2. Medicine

  3. Aidfenac SP Plus Tablet

Prescription drug
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Aidfenac SP Plus Tablet, Pack of 1 Tablet
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Extra 15% Off with Bank Offers

Composition :

DICLOFENAC-50MG + PARACETAMOL-325MG + SERRATIOPEPTIDASE-15MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Aidfenac SP Plus Tablet

Aidfenac SP Plus Tablet is used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual cramps, ear pain, and migraine headaches. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Aidfenac SP Plus Tablet is a combination of diclofenac, paracetamol, and serratiopeptidase. Diclofenac and paracetamol work by blocking the effect of cyclooxygenase (COX) enzymes, which produce other chemical prostaglandins. Serratiopeptidase is an anti-inflammatory agent that decreases swelling at the painful site.

In some cases, Aidfenac SP Plus Tablet may cause specific common side effects such as nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Aidfenac SP Plus Tablet should not be given to children as safety and efficacy have not been established. Keep your doctor informed about your health condition and any medications you're taking to rule out any side effects or interactions.

Uses of Aidfenac SP Plus Tablet

Aidfenac SP Plus Tablet is used in the treatment of pain and inflammation. The detailed uses of Aidfenac SP Plus Tablet are as follows:

  • Pain Relief: Aidfenac SP Plus Tablet is frequently used to treat mild to moderate pain from a variety of ailments, including menstrual cramps, headaches, and toothaches.
  • Anti-inflammatory Effects: The drug effectively reduces inflammation associated with musculoskeletal ailments, such as arthritis, helping to alleviate swelling and discomfort.
  • Post-Surgical Pain Management: Aidfenac SP Plus Tablet may be recommended following surgery to help control pain and promote comfort throughout the healing process.
  • Fever Reducer: Aidfenac SP Plus Tablet's antipyretic qualities help to reduce fever brought on by infections or other ailments.
  • Muscle Pain Relief: Whether caused by physical activity, injury, or underlying medical issues, Aidfenac SP Plus Tablet can help relieve muscle pain.

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Directions for Use

  • Aidfenac SP Plus Tablet should be taken after meals, to reduce the likelihood of gastrointestinal side effects.
  • Recommended to take Aidfenac SP Plus Tablet once daily or as advised by your doctor.
  • Administer Aidfenac SP Plus Tablet as a whole orally with water.
  • Avoid crushing, breaking, or chewing Aidfenac SP Plus Tablet.

Medicinal Benefits

  • Aidfenac SP Plus Tablet is a combination of three drugs: Diclofenac (a painkiller), Paracetamol (a fever reducer), and Serratiopeptidase (a protein enzyme).
  • Aidfenac SP Plus Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, swelling, period pain, ear pain, migraine, fever,  sore throat, nose pain, etc.
  • Aidfenac SP Plus Tablet increases the pain threshold and blood flow across the skin.
  • Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation.
  • Serratiopeptidase breaks down the abnormal proteins at the site of inflammation, thereby reducing inflammation.

How Aidfenac SP Plus Tablet Works

Aidfenac SP Plus Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain, swelling and fever. By blocking the COX enzyme's effect, fewer prostaglandins are produced, which reduces mild to moderate pain, inflammation and fever. Serratiopeptidase acts as a mucolytic (dissolves thick protein at the injured/affected site) and anti-inflammatory agent, thereby decreasing swelling at the painful site.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Aidfenac SP Plus Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Aidfenac SP Plus Tablet

Do not take more than the prescribed dose of Aidfenac SP Plus Tablet as it may cause serious side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Aidfenac SP Plus Tablet if you are allergic to paracetamol, diclofenac or serratiopeptidase.
  • Also, avoid taking Aidfenac SP Plus Tablet if you have/had severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, have undergone any heart bypass surgery, have had a heart attack, blood circulation problems or inflammation of the intestines.
  • Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding.
  • Aidfenac SP Plus Tablet may cause drowsiness and dizziness, so drive only if you are alert.
  • Aidfenac SP Plus Tablet is not recommended for children less than 10 years of age, as safety and effectiveness have not been established.
  • Avoid consuming alcohol with Aidfenac SP Plus Tablet as it could lead to increased drowsiness and increased risk of stomach bleeding.
  • Stop taking Aidfenac SP Plus Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.
  • Do not take any other NSAIDs for pain relief along with Aidfenac SP Plus Tablet unless prescribed.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacTenofovir alafenamide
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Aidfenac SP Plus Tablet:
Co-administration of Aidfenac SP Plus Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Aidfenac SP Plus Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacTenofovir alafenamide
Severe
How does the drug interact with Aidfenac SP Plus Tablet:
Co-administration of Aidfenac SP Plus Tablet and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Aidfenac SP Plus Tablet and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
DiclofenacFondaparinux
Severe
How does the drug interact with Aidfenac SP Plus Tablet:
Coadministration of Aidfenac SP Plus Tablet with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Aidfenac SP Plus Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacPiroxicam
Severe
How does the drug interact with Aidfenac SP Plus Tablet:
Taking Aidfenac SP Plus Tablet and piroxicam can increase the risk of side effects such as ulcers, inflammation (redness, swelling), bleeding.

How to manage the interaction:
Co-administration of Aidfenac SP Plus Tablet and Piroxicam can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacPonatinib
Severe
How does the drug interact with Aidfenac SP Plus Tablet:
Taking Aidfenac SP Plus Tablet with Ponatinib can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Aidfenac SP Plus Tablet and Ponatinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacTenofovir disoproxil
Severe
How does the drug interact with Aidfenac SP Plus Tablet:
Co-administration of Aidfenac SP Plus Tablet with tenofovir disoproxil may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Aidfenac SP Plus Tablet and Tenofovir disoproxil but they can be taken together if your doctor has prescribed them. However consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacIbrutinib
Severe
How does the drug interact with Aidfenac SP Plus Tablet:
Taking Aidfenac SP Plus Tablet with Ibrutinib can increase the risk of bleeding tendencies.

How to manage the interaction:
There may be a possible interaction between Aidfenac SP Plus Tablet and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.
DiclofenacDasatinib
Severe
How does the drug interact with Aidfenac SP Plus Tablet:
Taking Dasatinib together with Aidfenac SP Plus Tablet may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Aidfenac SP Plus Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.
DiclofenacEnoxaparin
Severe
How does the drug interact with Aidfenac SP Plus Tablet:
Taking Aidfenac SP Plus Tablet with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Aidfenac SP Plus Tablet and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
DiclofenacSulindac
Severe
How does the drug interact with Aidfenac SP Plus Tablet:
Co-administration of Aidfenac SP Plus Tablet and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Aidfenac SP Plus Tablet and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To prevent pressure sores, change your position every 2 hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot pack on the muscle for 15-20 minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Aidfenac SP Plus Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Aidfenac SP Plus Tablet as it may cause increased drowsiness.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant; your doctor will prescribe Aidfenac SP Plus Tablet only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor if you are breastfeeding; your doctor will decide whether Aidfenac SP Plus Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Aidfenac SP Plus Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Aidfenac SP Plus Tablet should not be given to children less than 10 years of age, as the safety and effectiveness have not been established.

FAQs

Aidfenac SP Plus Tablet is used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain‚ and migraine headaches.

Aidfenac SP Plus Tablet contains Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase is a protein enzyme that helps break down and dissolves the abnormal proteins at the inflammation site, thereby reducing pain.

Aidfenac SP Plus Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.

Diarrhoea might be a side-effect of Aidfenac SP Plus Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Aidfenac SP Plus Tablet should not be taken for longer durations unless prescribed by the doctor. If Aidfenac SP Plus Tablet has been prescribed for longer durations, regular monitoring of kidney function, liver function and blood count is advised, particularly in elderly patients.

Avoid taking Aidfenac SP Plus Tablet if you have ulcers in the stomach or intestines, bleeding problems or heart problems.

No, you should not use the Aidfenac SP Plus Tablet if you have stomach ulcers. Aidfenac SP Plus Tablet can irritate the stomach lining, worsen existing stomach ulcers, or even cause new ones to develop. If you have stomach ulcers, it's essential to consult with your doctor to discuss appropriate treatment options.

No, Aidfenac SP Plus Tablet is not a muscle relaxant.

The amount and frequency of your medication can vary depending on your health, age, and other medications you're taking. Always follow your healthcare professional's directions to use this medicine safely and correctly.

Yes, Aidfenac SP Plus Tablet contains diclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID).

Store in a cool and dry place away from sunlight. Keep Aidfenac SP Plus Tablet out of the sight and reach of children.

Aidfenac SP Plus Tablet can be safe when used as directed by a healthcare professional. However, like all medications, it has potential side effects and may interact with other medicines. It's important to consult with a doctor or pharmacist before starting or continuing to use this medication. They can assess your health situation and determine if it suits you.

Even if the pain is alleviated, this does not necessarily imply that the underlying condition has healed completely. Stopping the medicine prematurely may result in a return of your symptoms.

Yes, Aidfenac SP Plus Tablet can cause nausea and vomiting. These are common side effects of the medication, especially when taken on an empty stomach or in high doses. If nausea or vomiting is persistent or severe, it's important to seek medical attention.

Yes, Aidfenac SP Plus Tablet can cause dizziness. It is a common side effect of the medication, especially when starting the medication or taking a higher dose. If dizziness is persistent or severe, seeking medical attention is essential.

It is generally safe to use Aidfenac SP Plus Tablet with Vitamin B-Complex. However, you should always discuss with your doctor or pharmacist before combining any medications, especially if you have underlying health concerns or are taking other prescriptions. They can evaluate potential interactions and confirm that the combination is safe for you.

No, you should not take Aidfenac SP Plus Tablet for stomach pain. If you have stomach pain, you should consult a doctor to find out what's causing it and get the right therapy.

Yes, the use of Aidfenac SP Plus Tablet may cause damage to the kidneys. This may occur in some people, especially those at risk for kidney problems. If you are concerned about your risk of kidney damage while taking Aidfenac SP Plus Tablet, it's essential to talk to your doctor. They can monitor your kidney function, adjust your dosage, or recommend alternative medications if necessary.

Use of Aidfenac SP Plus Tablet during pregnancy is not advised unless prescribed by a doctor. Please consult your doctor if you are pregnant; your doctor will prescribe Aidfenac SP Plus Tablet only if the benefits outweigh the risks.

Common side effects of Aidfenac SP Plus Tablet may cause nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Aidfenac SP Plus Tablet may be unsafe for some people based on their medical condition. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.

Aidfenac SP Plus Tablet may interact with various medications. So, seek personalised medical guidance from your healthcare professional by knowing about all your medications.

Store in a cool and dry place away from sunlight. Keep Aidfenac SP Plus Tablet out of reach and out of sight from children.

Taking Aidfenac SP Plus Tablet with food is generally recommended to reduce the risk of stomach upset.

Country of origin

India
Other Info - AI45591

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 21, 2025 | 12:14 PM IST

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Reference

  1. https://ciplamed.com/content/cipzen-d-plus-tablets
  2. https://wellonapharma.com/product/finished/diclofenac-potassium-paracetamol-and-serratiopeptid
  3. https://vibcare.co.in/diclofenac-paracetamol-serratiopeptidase/http://www.salvavidaspharma.com/product/diclofenac-potassium-paracetamol-serratiopeptid/
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