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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Akusol-500 Injection 1's is used to treat symptoms associated with allergic reactions or inflammatory conditions. It helps treat arthritis, tennis elbow, and golfer's elbow, which cause swelling and pain in the joints and tendons. It is also useful in treating severe allergic reactions, asthma, ulcerative colitis, and Crohn's disease (inflammatory bowel disease).

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Synonym :

METHYLPREDNISOLONE SODIUM SUCCINATE

Manufacturer/Marketer :

Akumentis Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Akusol-500 Injection 1's

Akusol-500 Injection 1's is used to treat symptoms associated with allergic reactions or inflammatory conditions. It helps treat arthritis, tennis elbow, and golfer's elbow, which cause swelling and pain in the joints and tendons. It is also useful in treating severe allergic reactions, asthma, ulcerative colitis, and Crohn's disease (inflammatory bowel disease).

Akusol-500 Injection 1's contains methylprednisolone, a corticosteroid medicine. It works by suppressing certain chemical messengers in the body that cause inflammation and allergic conditions; thus, it effectively treats various medical conditions associated with allergies and inflammation.

Akusol-500 Injection 1's is administered by a doctor in a hospital setting. Do not self-administer. It may cause side effects like sleeping disorders, difficulty in thinking or being confused, memory loss, or mood swings. If any of these side effects are persistent, consult your doctor.

Inform your doctor before receiving Akusol-500 Injection 1's if you are allergic to corticosteroids or methylprednisolone, if you just had a vaccination or have a vaccination planned, or if you have a viral infection such as measles or chickenpox, shingles, or any other medical condition.

Uses of Akusol-500 Injection 1's

Akusol-500 Injection 1's is used to treat allergic and inflammatory conditions. The detailed uses of Akusol-500 Injection 1's are as follows:

  • Manages allergic reactions: Akusol-500 Injection 1's is effective in treating severe allergic responses such as asthma, drug allergies, and skin rashes by suppressing the immune system’s overactivity.
  • Reduces inflammation: Akusol-500 Injection 1's helps control inflammation in various conditions like arthritis, lupus, and inflammatory bowel disease by decreasing swelling, redness, and pain.
  • Used in autoimmune and respiratory disorders: Akusol-500 Injection 1's is also prescribed to manage autoimmune diseases and respiratory conditions like chronic obstructive pulmonary disease (COPD) and bronchitis.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Akusol-500 Injection 1's will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • Akusol-500 Injection 1's helps reduce inflammation and swelling in the body.
  • It suppresses an overactive immune system.
  • It provides quick relief from severe allergic reactions.
  • It helps reduce joint pain, stiffness, and inflammation.
  • Akusol-500 Injection 1's improves breathing by decreasing airway inflammation.
  • It helps control autoimmune and inflammatory responses.
  • It reduces redness, itching, and tissue irritation.
  • It provides effective relief in acute and severe inflammatory conditions.

How Akusol-500 Injection 1's Works

Akusol-500 Injection 1's contains methylprednisolone, a corticosteroid medicine. It works by suppressing the action of certain chemical messengers in the body that cause inflammation and allergic conditions; thus, it effectively treats various medical conditions associated with allergies and inflammation.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Akusol-500 Injection 1's

Akusol-500 Injection 1's is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose of this medicine may cause elevated blood pressure, retention of salt and water, which can result in swelling in your feet, legs, or arms, low blood potassium levels, which can lead to fatigue, cramping in the muscles, and weakness. Your doctor may take immediate necessary measures if an overdose is suspected.

Drug Warnings

  • Inform your doctor if you are allergic to steroids, methylprednisolone, or any components present in the Akusol-500 Injection 1's.
  • Consult your doctor if you are pregnant or breastfeeding before receiving Akusol-500 Injection 1's. Your doctor will weigh the benefits and potential risks before prescribing Akusol-500 Injection 1's for you.
  • Let your doctor know if you have bipolar disorder or depression, tuberculosis, diabetes, epilepsy, glaucoma, osteoporosis, myasthenia gravis (muscle weakness), stomach ulcers, high blood pressure or heart failure, liver or kidney problems or any viral infections or if you are about to undergo an organ transplantation procedure.
  • Akusol-500 Injection 1's is generally not recommended for use in children because it can cause growth and development delays as well as severe headaches with blurred vision or temporary visual problems.
  • Individuals with a weakened immune system should not receive any live vaccines while taking this medicine.

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Akusol-500 Injection:
Co-administration of Methylphenidate with Iohexol may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Akusol-500 Injection with Iohexol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Akusol-500 Injection:
Co-administration of Akusol-500 Injection and Vigabatrin together can increase the risk or severity of side effects associated with vision loss.

How to manage the interaction:
Taking Akusol-500 Injection with Vigabatrin is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Akusol-500 Injection:
When Akusol-500 Injection is taken with Mifepristone, it may decrease the levels of Akusol-500 Injection, which may be less effective in treating your condition.

How to manage the interaction:
Taking Akusol-500 Injection with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Akusol-500 Injection:
Coadministration of Akusol-500 Injection with Atazanavir may significantly increase the blood levels of Akusol-500 Injection.

How to manage the interaction:
Although taking Akusol-500 Injection and Atazanavir together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thin skin, easy bruising, irregular periods, bruises, too much facial or body hair, strange fat distribution, infection, or a bad asthma attack - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Akusol-500 Injection:
The use of Etanercept with Akusol-500 Injection can increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Akusol-500 Injection, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Akusol-500 Injection:
Co-administration of Akusol-500 Injection and Gatifloxacin together can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Akusol-500 Injection and Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Akusol-500 Injection:
Taking Thalidomide together with Akusol-500 Injection may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Akusol-500 Injection together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Akusol-500 Injection:
Using leflunomide together with Akusol-500 Injection may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction between leflunomide and Akusol-500 Injection, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Akusol-500 Injection:
Co-administration of Ketoconazole and Akusol-500 Injection the levels of Akusol-500 Injection in the blood may be greatly increased.

How to manage the interaction:
Although taking Ketoconazole and Akusol-500 Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any of the symptoms such as swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts(blurred vision), irregular menstruation, excessive facial or body hair growth, abnormal body fat distribution, especially in the face, neck, back, and waist, decreased ability to fight infections, or a severe asthma attack, consult a doctor. Without consulting a doctor, never stop taking any drugs.
How does the drug interact with Akusol-500 Injection:
Using tofacitinib together with Akusol-500 Injection may increase the risk of serious infections.

How to manage the interaction:
Although taking Akusol-500 Injection and Tofacitinib together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or bleeding, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Healthy Dietary Choices:

  • Consume antioxidant-rich foods such as blueberries, tomatoes, cherries, squash, and bell peppers to reduce inflammation.
  • Include probiotic-rich foods to help strengthen the immune system against allergies.
  • Eat quercetin-rich foods like apples, cherries, spinach, broccoli, and blueberries to support allergy control.
  • Add seasonal fruits, vegetables, whole grains, healthy fats, and fish to maintain overall health.
  • Limit foods that may trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Reduce intake of high-sugar foods that can worsen inflammation.
  • Avoid processed meats, refined carbohydrates, trans fats, alcohol, and excess sugar as they may aggravate inflammation.

Lifestyle and Wellness:

  • Reducing stress helps improve immune function and lowers allergy risk.
  • Maintaining a regular sleep schedule supports overall immunity and recovery.

Habit Forming

No

Therapeutic Class

CORTICOSTEROIDS

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Alcohol

Caution

No interaction was found. However, limit alcohol consumption as a precautionary measure.

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Pregnancy

Caution

Inform your doctor if you are pregnant or suspect or planning pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Akusol-500 Injection 1's.

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Breast Feeding

Safe if prescribed

Akusol-500 Injection 1's is considered safe to be used during breastfeeding. If you are breastfeeding, inform your doctor before receiving this injection. Your doctor will weigh the benefits and potential risks before prescribing Akusol-500 Injection 1's.

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Driving

Caution

Akusol-500 Injection 1's has no or insignificant effect on one's ability to drive or operate machinery. In rare cases, Akusol-500 Injection 1's may cause blurred vision or other visual disturbances. If you experience these symptoms, do not drive or operate machinery until you are alert.

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Liver

Caution

If you have a history of liver diseases/conditions or ongoing liver conditions, inform your doctor before receiving Akusol-500 Injection 1's. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

If you have a history of kidney diseases/conditions or ongoing kidney conditions, inform your doctor before receiving Akusol-500 Injection 1's. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Children

Caution

Akusol-500 Injection 1's is generally not recommended for use in children because it can delay growth and development as well as severe headaches with blurred vision or temporary visual problems. Before prescribing this medication to your child, your paediatrician may weigh the benefits and risks.

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Heart

Caution

Akusol-500 Injection 1's may be used in heart patients but require close monitoring due to risks like fluid retention and elevated blood pressure. Always consult your doctor to ensure it's safe for your specific heart condition.

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Geriatrics

Caution

Geriatric patients can receive Akusol-500 Injection 1's, but it may be more sensitive to side effects like fluid retention, elevated blood pressure, or blood sugar changes. It's essential to have the dosage and duration tailored by a doctor based on your overall health and other medications.

FAQs

Akusol-500 Injection 1's belongs to the corticosteroid drug class. It is used to treat symptoms associated with allergic reactions or inflammatory conditions. It is primarily used to treat arthritis, tennis elbow, and golfer's elbow, which cause swelling and pain in the joints and tendons.

Akusol-500 Injection 1's contains the corticosteroid medication methylprednisolone. It works by blocking the transmission of certain chemical messengers in the body that cause inflammation and allergic reactions, effectively treating a variety of medical conditions associated with allergic and inflammatory reactions.

Corticosteroid medications such as Akusol-500 Injection 1's can alter how your body processes carbs and sugars (glucose). They can elevate your blood sugar by preventing insulin from working. If you have diabetes, your blood glucose levels need to be monitored regularly while you are on treatment with this medicine.

Akusol-500 Injection 1's is not recommended for treating viral infections such as measles, chickenpox, shingles, or any other viral conditions.

Complete the entire course of treatment with Akusol-500 Injection 1's even if you feel better after receiving a few doses, as abrupt stopping may lead to undesirable effects.

While taking Akusol-500 Injection 1's, do not receive a "live" vaccine (including measles, mumps, polio, chickenpox) as the vaccine may not work, and you may develop the disease again.

Country of origin

India

Manufacturer/Marketer address

204, 2nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India.
Other Info - AKU0037

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