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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Alfakit Tablet is used to treat chronic kidney disease. It contains Alpha Ketoanalogue, which works by lowering urea levels in the blood and improving kidney function. In some cases, this medicine may cause side effects such as increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

ALPHA KETOANALOGUE

Manufacturer/Marketer :

Plasoron Biotech Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Alfakit Tablet

Alfakit Tablet is widely used in the treatment of chronic kidney disease. Chronic kidney disease (CKD) is a long-term condition where the kidneys don't work as they should.

Alfakit Tablet contains Alpha Ketoanalogue, which prevents the unnecessary increase in urea levels in the blood due to the intake of non-essential amino acids in patients with kidney failure. Thereby improving renal function.

Not everyone who takes Alfakit Tablet will experience these side effects. Common side effects of Alfakit Tablet include increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time.

Take Alfakit Tablet with food orally (by mouth). Depending on your medical condition, your doctor will decide the dose and duration of the medicine. However, it is advised not to take more than the prescribed dose of Alfakit Tablet . Do not chew, crush or bite the medicine.

Do not take Alfakit Tablet if you are allergic to any components present in Alfakit Tablet . Inform your physician if you are pregnant or a breastfeeding mother before using Alfakit Tablet . Please do not stop taking Alfakit Tablet without consulting your doctor. Avoid consuming alcohol during the treatment to avoid unpleasant side effects.

Uses of Alfakit Tablet

Alfakit Tablet used in the treatment of chronic kidney disease (CKD). The detailed uses of Alfakit Tablet are as follows:

  • Chronic Kidney Disease (CKD): Alfakit Tablet helps to manage CKD by reducing the accumulation of nitrogen waste products in the blood, slowing disease progression, and delaying the need for dialysis.
  • Kidney Function Support: Alfakit Tablet supports kidney function by reducing uremia and waste accumulation, providing essential amino acids, and reducing the strain on the kidneys.
  • Enhances Nutritional Status: Alfakit Tablet enhances nutritional status by providing essential ketoacids, which promote protein synthesis, reduce muscle wasting, and improve overall health.

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Directions for Use

  • Alfakit Tablet can be taken with meals to increase absorption.
  • It is advised to take this medication three times daily or as prescribed by your doctor.
  • Swallow Alfakit Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

Key Benefits

  • Alfakit Tablet is used in the treatment of chronic kidney disease.
  • It is best if taken along with a low-protein diet, as it helps delay the progression of kidney diseases.
  • Make healthy lifestyle changes and ensure that your underlying conditions are well-managed.

How Alfakit Tablet Works

Alfakit Tablet contains 'Alpha Ketoanalogue', which prevents the unnecessary increase in urea levels in the blood due to the intake of non-essential amino acids in patients with kidney failure. Thereby improving renal function. It is best if taken along with a low-protein diet as it helps delay the progression of kidney diseases.

Storage

Store in a cool and dry place away from sunlight
Side effects of Alfakit Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Alfakit Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include hypotension (low blood pressure), fever, rapid pulse, and general symptoms of shock. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Alfakit Tablet if you are allergic to any components present in it. 
  • It is advised not to stop taking Alfakit Tablet without consulting your doctor.
  • Alfakit Tablet should be used in pregnant and breastfeeding women only if clinically needed and the benefits outweigh the risks.
  • Avoid consuming alcohol along with Alfakit Tablet  as it may lead to unpleasant side effects.
  • People with chronic kidney disease (CKD) may need to closely monitor sodium and phosphorus in foods, especially if their kidney disease is advanced.
  • Alfakit Tablet is not recommended for use in children below 18 years of age as the safety has not been established.

Drug-Drug Interactions

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TryptophanSafinamide
Critical
TryptophanTranylcypromine
Critical

Drug-Drug Interactions

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TryptophanSafinamide
Critical
How does the drug interact with Alfakit Tablet:
Taking Safinamide with Alfakit Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Alfakit Tablet is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
TryptophanTranylcypromine
Critical
How does the drug interact with Alfakit Tablet:
Taking tranylcypromine with Alfakit Tablet can increase the risk of serotonin syndrome ( high levels of serotonin in body which result in shivering, high fever, diarrhea & muscle stiffness) .

How to manage the interaction:
Taking Tranylcypromine with Alfakit Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TryptophanParoxetine
Severe
How does the drug interact with Alfakit Tablet:
Coadministration of Paroxetine with Alfakit Tablet can increase the side effects of paroxetine.

How to manage the interaction:
Although there is a possible interaction between Paroxetine and Alfakit Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TryptophanPentazocine
Severe
How does the drug interact with Alfakit Tablet:
Coadministration of Pentazocine with Alfakit Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Pentazocine and Alfakit Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TryptophanVilazodone
Severe
How does the drug interact with Alfakit Tablet:
When Vilazodone is taken with Alfakit Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Alfakit Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
TryptophanRizatriptan
Severe
How does the drug interact with Alfakit Tablet:
Taking Rizatriptan with Alfakit Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Alfakit Tablet and Rizatriptan, it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking of hands and legs, incoordination, stomach cramps, nausea, vomiting, and loose stools, contact a doctor. Do not discontinue any medications without consulting a doctor.
TryptophanVenlafaxine
Severe
How does the drug interact with Alfakit Tablet:
When venlafaxine is taken with Alfakit Tablet, the risk of serotonin syndrome increases (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
There may be a possibility of interaction between Venlafaxine and Alfakit Tablet, but it can be taken if prescribed by a doctor. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
TryptophanCyclobenzaprine
Severe
How does the drug interact with Alfakit Tablet:
Taking Cyclobenzaprine with Alfakit Tablet might raise serotonin hormone levels which can increase the risk of developing side effects.

How to manage the interaction:
Taking Cyclobenzaprine with Alfakit Tablet can possibly lead to an interaction. It can be taken if prescribed by doctor. However, if you experience fever, palpitations, excessive sweating, muscle spasm, or diarrhea, contact a doctor immediately. Do not discontinue the medications without consulting a doctor.
TryptophanSelegiline
Severe
How does the drug interact with Alfakit Tablet:
When Alfakit Tablet is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Alfakit Tablet and Selegiline, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea-call a doctor. Do not stop using any medications without a doctor's advice.
TryptophanMirtazapine
Severe
How does the drug interact with Alfakit Tablet:
Using Alfakit Tablet together with mirtazapine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Mirtazapine with Alfakit Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs feeling confused, seeing or hearing things that aren't there, having a seizure, a fast heartbeat, a high temperature, sweating a lot, trembling or shaking, having trouble seeing clearly, muscle spasms or stiffness, difficulty moving, stomach pain, feeling sick, throwing up, or having diarrhea, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • ​​It is best if taken along with a low-protein diet as it helps delay the progression of kidney diseases.
  • People with kidney problems are advised to limit sodium in their diet, including added salt.
  • Olive oil is a healthy source of fat- and phosphorus-free source, making it an excellent option for people with kidney disease.
  • Bulgur is a whole-grain wheat product that is a terrific, kidney-friendly alternative to other whole grains high in phosphorus and potassium.
  • Blueberries are packed with nutrients and are one of the best sources of antioxidants you can eat.

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

All Substitutes & Brand Comparisons

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Alcohol

Safe if prescribed

You are recommended not to consume alcohol along with Alfakit Tablet to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

Alfakit Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. Please consult the doctor; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Caution should be exercised, and it is advisable to consult a doctor before using it. The doctor will prescribe if the doctor thinks the benefits outweigh the risks.

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Driving

Safe if prescribed

Drive only if you are physically stable and mentally focused. If you experience drowsiness after taking this medication, you should not drive or operate machinery or vehicles.

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Liver

Consult your doctor

Inform your doctor before taking Alfakit Tablet if you have a liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Alfakit Tablet can be taken safely if prescribed. Usually, it does not affect the kidney.

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Children

Safe if prescribed

The safety and efficacy of Alfakit Tablet in children have not been established. Alfakit Tablet is not recommended in children.

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Heart

Alfakit Tablet is generally safe for heart patients, but they should be taken under medical supervision.

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Geriatrics

Consult your doctor

Geriatric patients may take Alfakit Tablet with caution, as age-related kidney or calcium metabolism changes require medical supervision. Always consult your doctor to ensure it's suitable for your health status and other medications.

FAQs

Alfakit Tablet is used in the treatment of chronic kidney disease.

Alfakit Tablet mimics the same catabolic pathways as amino acids and works by improving the body's metabolism, thereby improving renal function.

To treat your condition effectively, continue taking Alfakit Tablet for as long as your doctor has prescribed. Please do not stop taking Alfakit Tablet without consulting your doctor.

CKD is usually caused by various conditions such as high blood pressure, diabetes, high cholesterol, kidney infections, kidney inflammation, kidney stones that keep coming back, an enlarged prostate, and long-term or regular use of certain medicines such as lithium and non-steroidal anti-inflammatory drugs (NSAIDs).

CKD can be diagnosed using blood and urine tests. These tests look for high levels of certain substances in the blood and urine that show your kidneys are malfunctioning. The results of these tests can be used to determine the stage of your kidney disease.

There are usually no symptoms of kidney disease in the early stages. At a more advanced stage, symptoms can include tiredness, swollen ankles, feet or hands, shortness of breath, feeling sick, and blood in your pee (urine). It may only be diagnosed if you have a blood or urine test for another reason and the results show a possible problem with your kidneys.

Alfakit Tablet contains Alpha Ketoanalogue, a nutritional supplement used to treat chronic kidney disease.

No, Alfakit Tablet is not same as arginine alpha-ketoglutarate. Alfakit Tablet contains alpha ketoanalogue which is a combination of different amino acids, whereas arginine alpha-ketoglutarate is a combination of alpha-ketoglutaric acid &essential amino acid arginine.

Alfakit Tablet should be swallowed as a whole with water; do not crush or chew it.

Side effects of Alfakit Tablet include increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

3M India Ltd, Concorde Block, UB City, #24, Vittal Mallya Road, Bangalore, Karnataka - 560001 India
Other Info - ALF0127

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