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compositionComposition:ALPRAZOLAM-0.25MG+MELATONIN-3MG
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Prescription Medicine
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Alprax Z 0.25mg Tablet 10's is used to treat sleeplessness (insomnia). Besides this, it also helps to provide a calming effect on anxiety disorder and panic disorder. It contains Alprazolam and Melatonin, which reduces the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the night time. It may cause common side effects such as drowsiness, tiredness, headache, depressed mood, daytime drowsiness, stomach pain, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ALPRAZOLAM-0.25MG+MELATONIN-3MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Alprax Z 0.25mg Tablet 10's

Alprax Z 0.25mg Tablet 10's is an oral prescription medication used to manage short-term sleeplessness (insomnia) that is directly linked to anxiety. It acts on the brain to calm excessive mental worry while signalling to your body that it is time to rest. This medicine is designed to help you fall asleep faster and stay asleep throughout the night.

To achieve the best results, you should take this medicine consistently at the exact frequency recommended by your doctor, typically right before bedtime. It can be taken with or without food, though taking it with a heavy meal may delay its effects. Making healthy lifestyle choices, such as reducing screen time before bed, can further support your sleep quality.

While taking Alprax Z 0.25mg Tablet 10's, some people may experience mild side effects like daytime drowsiness, lightheadedness, or a dry mouth. However, you must contact your doctor immediately if you notice serious issues such as severe confusion, memory gaps, or extreme mood changes. Never ignore these signs, as they require professional medical evaluation.

Do not take this if you have a history of severe breathing problems, sleep apnoea, severe liver damage, or substance abuse. It is highly important to share your full medical history with your doctor before starting this treatment. They will help determine if this medication is safe and appropriate for your specific health profile.

This medicine can interact dangerously with alcohol, causing extreme sleepiness and slowed breathing, while smoking can make the treatment less effective. Certain user groups, including pregnant women, breastfeeding mothers, and elderly individuals, must consult their doctor before using this medicine, as they may be more sensitive to its side effects.

Uses of Alprax Z 0.25mg Tablet 10's

Alprax Z 0.25mg Tablet 10's is used to manage short-term sleeplessness (insomnia). The detailed uses of Alprax Z 0.25mg Tablet 10's are as follows:

  • Anxiety-associated insomnia: Alprax Z 0.25mg Tablet 10's helps by calming an overactive mind, reducing physical tension, and allowing you to transition easily into quiet, restful sleep.
  • Disrupted sleep cycles: By reinforcing your body's natural internal clock, this medicine helps reduce frequent nighttime awakenings and improves overall sleep structure.

 

Key Benefits

Taking Alprax Z 0.25mg Tablet 10's can help you break the exhausting cycle of sleepless nights caused by worry and stress. By addressing both the mental and physical aspects of anxiety-induced insomnia, it offers significant, real-world relief.

  • Faster sleep onset: It helps you quieten racing thoughts rapidly so you spend less time tossing and turning in bed.
  • Deeper sleep quality: The medication supports longer periods of uninterrupted sleep, allowing you to wake up feeling more restored.
  • Reduced night anxiety: It keeps the physical symptoms of anxiety under control overnight, preventing sudden panic-like awakenings.
     

Directions for Use

To get the full benefit of Alprax Z 0.25mg Tablet 10's and minimise side effects, follow these simple guidelines:

  • Take this medicine by mouth exactly as directed by your doctor, usually once a day right before you go to bed.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can alter how the medicine is released into your system.
  • You can take this medication with or without food, but avoiding heavy or high-fat meals right before your dose will help it work more quickly.
  • Ensure you have at least 7 to 8 hours of uninterrupted sleep time available after taking this medicine to avoid feeling extremely groggy the next day.
  • Always follow your doctor's exact instructions and never change your dose or stop taking it without consulting them first.
     

How Alprax Z 0.25mg Tablet 10's Works

Alprax Z 0.25mg Tablet 10's works through the combined action of its two active ingredients: alprazolam and melatonin. Together, they target both the mental triggers of sleeplessness and the physical signals your body needs to rest. The first active component, alprazolam, belongs to a class of medicines called benzodiazepines. It works by increasing the activity of a natural calming chemical in your brain known as GABA. By boosting GABA, this component slows down overactive nerve signals, which reduces severe anxiety and relaxes tense muscles. The second active component, melatonin, is a synthetic version of the natural hormone your brain produces in response to darkness. It acts directly on receptors in the brain to signal that it is nighttime, helping to reset and regulate your natural sleep-wake cycle. Together, these components prepare both your mind and body for sleep.
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Alcohol

Unsafe

Alcohol is sedative in nature, so taking it with Alprax Z 0.25mg Tablet 10's may interrupt the sleep cycle. Alcohol may worsen the effects of Alprax Z 0.25mg Tablet 10's so one should not consume it with Alprax Z 0.25mg Tablet 10's.

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Pregnancy

Unsafe

Alprax Z 0.25mg Tablet 10's is a category D pregnancy drug. It is not recommended for use during pregnancy, especially in the second and third trimesters as it may cause harm to the unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Alprax Z 0.25mg Tablet 10's as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Alprax Z 0.25mg Tablet 10's may cause dizziness, double vision, or drowsiness in some people. It is an offence to drive if Alprax Z 0.25mg Tablet 10's affects you. Therefore, avoid driving if you feel drowsy, dizzy, or experience any vision problems after taking Alprax Z 0.25mg Tablet 10's.

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Liver

Caution

Take Alprax Z 0.25mg Tablet 10's with caution, especially if you have or had a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Alprax Z 0.25mg Tablet 10's with caution, especially if you have or had a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Not enough scientific data available for Alprax Z 0.25mg Tablet 10's, hence it is best to consult a child specialist.

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Heart

Caution

Extreme caution should be exercised in cardiac patients while taking Alprax Z 0.25mg Tablet 10's. The patient should be closely monitored for any changes.

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Geriatrics

Unsafe

Alprax Z 0.25mg Tablet 10's should be avoided in geriatric patients, as it can cause serious adverse effects like liver/kidney damage, dizziness or drowsiness.

What if I have taken an overdose of Alprax Z 0.25mg Tablet 10's

Do not take more than the prescribed dose of Alprax Z 0.25mg Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Limit caffeine intake: Avoid coffee, tea, chocolates, and energy drinks in the afternoon and evening, as caffeine directly counteracts the sleep-promoting effects of melatonin.
  • Keep a strict sleep schedule: Go to bed and wake up at the exact same time every day, even on weekends, to help train your brain's sleep-wake cycle.
  • Create a dark environment: Keep your bedroom as dark as possible. Avoid using smartphones, tablets, or computers for at least one hour before bed, as their blue light stops natural melatonin production.
  • Avoid alcohol: Do not drink alcohol while taking this medicine, as it disrupts normal sleep patterns and severely increases the risk of dangerous breathing problems.

 

health query

Have a query?

How Soon It Starts Working

The time required for Alprax Z 0.25mg Tablet 10's to start to work: Alprax Z 0.25mg Tablet 10's ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Alprax Z 0.25mg Tablet 10's last: The duration of action for Alprax Z 0.25mg Tablet 10's is not clinically established.

What if you forget to take Alprax Z 0.25mg Tablet 10's

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store Alprax Z 0.25mg Tablet 10's at a controlled room temperature, strictly between 15°C and 30°C. •Keep the tablets in their original packaging to protect them from direct light, high heat, and moisture.

Drug Warnings

  • Risk of habit formation: This medicine is meant for short-term use. Taking it for longer periods can lead to physical and psychological dependence.
  • Avoid sudden stoppage: Stopping this medicine abruptly can cause severe withdrawal symptoms, including returning insomnia, shaking, and sweating. If treatment needs to be discontinued, your doctor will create a tapering schedule that gradually reduces your dose over time.
  • Do not drive: This medicine causes drowsiness and slows your reaction times. Do not drive, ride a bicycle, or operate heavy machinery until you are fully alert.
  • Check the packaging: Always inspect the tablet blister pack before use. Do not take the medicine if the packaging is torn, punctured, or shows signs of tampering.
  • Inform your surgeon: If you are scheduled to undergo any surgery or medical procedure requiring anesthesia, inform your doctor well in advance that you are taking this medicine.
  • Prescription-only medicine: Alprazolam is a Schedule H prescription medicine in India. It can only be obtained with a valid prescription from a registered medical practitioner and is not available for over-the-counter purchase. A new prescription may be required for subsequent dispensing, depending on applicable regulations and pharmacy requirements. 
     

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Drug-Drug Interactions

  • Opioid pain relievers: Taking this medicine with opioid pain medications may cause excessive drowsiness, severe breathing difficulties, profound sedation, coma, or other life-threatening complications.
  • Other central nervous system (CNS) depressants: Combining Alprax Z 0.25mg Tablet 10's with other sleeping pills, anti-anxiety medications, muscle relaxants, or similar medicines can increase drowsiness, impair coordination, and raise the risk of serious sedation.
  • Fluvoxamine: This antidepressant may slow the breakdown of alprazolam, leading to higher drug levels in the body and an increased risk of side effects such as excessive sleepiness, dizziness, and impaired concentration.
  • Ketoconazole and other strong CYP3A4 inhibitors: Medicines such as ketoconazole can significantly reduce the metabolism of alprazolam, increasing blood concentrations and raising the risk of excessive sedation, dizziness, impaired coordination, and other adverse effects.
  • Macrolide antibiotics (e.g., erythromycin): Erythromycin and related antibiotics may inhibit CYP3A4 enzymes, resulting in higher alprazolam levels and an increased likelihood of drowsiness, confusion, and psychomotor impairment. Your doctor may recommend closer monitoring or dosage adjustments.

Drug-Food Interactions

  • Grapefruit and grapefruit juice: Consuming grapefruit products may interfere with the breakdown of alprazolam in the liver, leading to increased drug levels in the bloodstream and a higher risk of side effects. It is generally recommended to avoid grapefruit while taking Alprax Z 0.25mg Tablet 10's.

Drug-Disease Interactions

  • Severe breathing disorders: Patients with conditions such as asthma, chronic obstructive pulmonary disease (COPD), or sleep apnoea may be at increased risk of breathing difficulties because this medicine can further suppress respiratory function.
  • Severe liver disease: Impaired liver function may reduce the body's ability to clear this medicine effectively, increasing the risk of drug accumulation, excessive sedation, and confusion.
  • Myasthenia gravis: This neuromuscular condition may worsen with the muscle-relaxing effects of alprazolam, potentially increasing muscle weakness and related symptoms.
     

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[SEDATIVE-HYPNOTIC DRUGS]

FAQs

Alprax Z 0.25mg Tablet 10's belongs to a class of medication called sedatives and hypnotics, primarily used to treat sleeplessness (insomnia). Besides this, it also helps to provide a calming effect on anxiety disorder and panic disorder.
Alprax Z 0.25mg Tablet 10's is a combination of two medicines: Alprazolam and Melatonin, which helps a person fall asleep faster and stay asleep during the night. Alprazolam is a benzodiazepine (BZD) that increases the activity of a chemical messenger in the brain known as GABA, reducing the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. On the other hand, Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the nighttime.
It is advised not to take Alprax Z 0.25mg Tablet 10's if you have a bleeding disorder as taking this medicine may worsen the medical condition. The use of Alprax Z 0.25mg Tablet 10's is restricted in patients dealing with diabetes and depression.
It is suggested not to indulge in any heavy exercise like running or put up heavyweights as it can make you active and wake for a long time. However, you can practice some mindful activities like meditation to make yourself relax and sleep properly. Doing heavy workouts before bed increases blood circulation and body temperature of the body and creates difficulty sleeping. Your bedroom should be dark and should be mend for only sleep.
Yes, Alprax Z 0.25mg Tablet 10's may cause drowsiness, dizziness, slowed reflexes, or next-day sleepiness in some people. If you feel sleepy the next morning, avoid driving, operating machinery, or performing activities that require mental alertness until you are fully awake. Getting a full 7–8 hours of sleep after taking the medicine may help reduce morning grogginess. If excessive sleepiness persists, consult your doctor as your dose may need adjustment.
Alprax Z 0.25mg Tablet 10's should generally be used only for a short duration and exactly as prescribed by your doctor. Long-term or regular use may lead to dependence, reduced effectiveness, withdrawal symptoms, and excessive daytime drowsiness. If your sleep problems continue, consult your doctor for reassessment rather than increasing the duration of use on your own.
Yes, Alprax Z 0.25mg Tablet 10's can be habit-forming and may cause physical or psychological dependence, particularly when used for long periods or at higher doses than prescribed. Take it exactly as directed by your doctor and do not increase the dose or duration on your own.
Alprax Z 0.25mg Tablet 10's is not used for pain relief. It is used to treat sleeplessness (insomnia) and also helps to provide a calming effect on anxiety and panic disorders.
Alprax Z 0.25mg Tablet 10's is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It is important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
No. Alprax Z 0.25mg Tablet 10's is not an opioid or narcotic medicine. It contains alprazolam, a benzodiazepine, and melatonin, a hormone supplement used to regulate sleep.
Alprax Z 0.25mg Tablet 10's has antidepressant properties. Alprazolam alleviates sadness and anxiety, while melatonin regulates sleep and stimulates neurogenesis. Please consult a doctor before using it to ensure safety.
Alprax Z 0.25mg Tablet 10's is not used for treating a hangover. It is used for anxiety and panic disorders as well as helps to regulate sleep. For hangover relief stay hydrated, have some rest, and consider over-the-counter pain relievers if needed. If it persists or worsens consult a doctor for appropriate treatment.
Yes, you can take Alprax Z 0.25mg Tablet 10's for anxiety under medical guidance. But make sure to follow your doctor's instructions strictly to avoid addiction or side effects and have optimal results.
Alprax Z 0.25mg Tablet 10's can show the effect of reducing blood pressure through relaxation. But prolonged usage may lead to negative impact. Consult your doctor for personalized advice which is suitable to your condition without causing any side effects.
Generally, Alprax Z 0.25mg Tablet 10's does not lead to weight gain. However, an increased or decreased appetite may cause weight gain or weight loss in some people depending on the individual response to the medication. Please talk to your doctor if you have any concerns about weight gain.
No, avoid taking Alprax Z 0.25mg Tablet 10's with hydrocodone. As Alprax Z 0.25mg Tablet 10's interacts with hydrocodone (a synthetic opioid derivative of codeine) and causes negative side effects. Therefore, it is a better idea to discuss with your doctor before taking any medication while on treatment with Alprax Z 0.25mg Tablet 10's to ensure safety.
Generally, taking Alprax Z 0.25mg Tablet 10's with paracetamol is safe. However, it is important to consult your doctor before combining medications to ensure there are no potential interactions or side effects specific to your health situation.
The common side effects of Alprax Z 0.25mg Tablet 10's that may occur in some individuals are drowsiness, tiredness, headache, depressed mood, daytime drowsiness, stomach pain, and dizziness. Most of these side effects of Alprax Z 0.25mg Tablet 10's do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor.
No, you must completely avoid alcohol while taking this medicine. Alcohol interacts with the active ingredients to cause extreme drowsiness, dizziness, and dangerously slow breathing. Talk to your doctor if you find it hard to avoid alcohol.
You should avoid taking this medicine during pregnancy and breastfeeding, as the active ingredients can pass to your baby and cause serious drowsiness or developmental issues. Talk to your doctor for safer alternatives.
This medicine usually starts working within 30 to 60 minutes. It is best to take it right before you get into bed and are ready to sleep. Talk to your doctor if you do not feel sleepy after taking it.
No, you should not stop taking Alprax Z 0.25mg Tablet 10's suddenly without consulting your doctor. Abrupt discontinuation may cause withdrawal symptoms such as anxiety, restlessness, sweating, shaking, rebound insomnia, and other symptoms. Your doctor will gradually reduce the dose to stop treatment safely.
It is not recommended to mix this medicine with other sleep aids or herbal remedies, as doing so can cause excessive sedation and breathing issues. Always tell your healthcare provider about everything you are taking. Talk to your doctor before combining any treatments.

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Country of origin

INDIA

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India.
Other Info - ALP0045

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