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compositionComposition:SITAGLIPTIN-100MG
prescription
Prescription Medicine
info
Alsita-100 Tablet 10's
Alsita-100 Tablet 10's
Alsita-100 Tablet 10's

Alsita-100 Tablet is used to lower high blood sugar levels in patients who consistently follow a balanced diet and exercise. It contains Sitagliptin, which works by increasing the amount of insulin in the body. It may cause side effects such as upper respiratory tract infections, headaches, and nasopharyngitis (inflammation of the nasal passages). Before starting this medicine, inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SITAGLIPTIN-100MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Alsita-100 Tablet

Alsita-100 Tablet is a prescription medication used to lower blood sugar levels in adults with type 2 diabetes mellitus. It helps control blood sugar when used alongside proper lifestyle changes. This medicine is not for treating type 1 diabetes or diabetic ketoacidosis.

For this medicine to work effectively, you must take it consistently every day, usually once daily. You can take it with or without food. Combining this medication with healthy lifestyle choices, such as eating a balanced diet and exercising regularly, helps you get the best results from your treatment.

While taking Alsita-100 Tablet , most people tolerate it well, but some may experience mild side effects like a stuffy nose, headache, or throat irritation. Serious side effects are rare, but you must contact your doctor immediately if you experience severe, persistent stomach pain that spreads to your back, as this can be a sign of a serious pancreatic condition.

Do not take this if you have a known severe allergic reaction to this medication or any of its ingredients. Before starting this treatment, talk to your doctor if you have a history of kidney disease, heart failure, or problems with your pancreas, as you may require special monitoring or a different dose.

This medicine can interact with other treatments, especially other diabetes medications like insulin or sulfonylureas, which can increase your risk of low blood sugar. Avoid excessive alcohol consumption while taking this medication, as it can alter your blood sugar levels. If you are pregnant, planning to breastfeed, or are an older adult, consult your doctor to ensure this is the safest option for you.

Uses of Alsita-100 Tablet

Alsita-100 Tablet is used to improve blood sugar control in adults with type 2 diabetes mellitus. The detailed uses of Alsita-100 Tablet are as follows:

  • Type 2 Diabetes Mellitus: Alsita-100 Tablet helps lower blood sugar levels in adults whose diabetes is not sufficiently controlled by diet and exercise alone, reducing the risk of long-term diabetes complications.

Key Benefits

Alsita-100 Tablet contains Alsita-100 Tablet , which helps improve blood sugar control and supports long-term diabetes management. The key benefits of Alsita-100 Tablet include: 

  • Controls Blood Sugar Levels: Helps maintain steady blood sugar levels throughout the day and reduces rises in blood sugar after meals.
  • Supports Natural Insulin Release: Helps the body release insulin when blood sugar levels increase, improving glucose control after eating.
  • Helps Prevent Blood Sugar Spikes: Reduces sudden increases in blood sugar levels following meals, promoting more consistent energy levels.
  • Weight-Neutral Support: Unlike some diabetes medicines, Alsita-100 Tablet does not typically cause weight gain.
    Low Risk of Low Blood Sugar: When used on its own, it carries a low risk of causing hypoglycaemia because it works in a glucose-dependent manner.
  • Protects Long-Term Health: Good blood sugar control may help reduce the risk of diabetes-related complications affecting the nerves, kidneys, eyes, and cardiovascular system.
Side effects of Alsita-100 Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Get ample rest; this helps your stomach to settle.
  • Eat soft and easy-to-digest foods like white rice, bananas, crackers and apple sauce.
  • Include probiotics-rich food like yoghurt, kefir, or miso, as they help maintain gut functioning.
  • Wash your hands properly before preparing/eating food and after using the toilet.
  • Drink water, broth or diluted fruit juice to replace electrolytes and lost fluids.
  • Avoid caffeine, alcohol, high-fat, fried and fast foods, as well as sweetened beverages.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

To get the maximum benefit from treatment with Alsita-100 Tablet , follow these instructions carefully: 

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or split the tablet.
  • You can take this medicine with or without food.
  • Try to take your dose at the same time every day to keep a steady amount of medicine in your body.

Always follow your doctor's exact instructions regarding your treatment plan. Do not alter your dose or stop taking this medication without consulting your healthcare provider first.

How Alsita-100 Tablet Works

Alsita-100 Tablet in Alsita-100 Tablet belongs to a class of medicines called DPP-4 inhibitors. It works by blocking the action of an enzyme called dipeptidyl peptidase-4 (DPP-4). This enzyme normally breaks down natural hormones in your body known as incretins. Incretin hormones are released by your intestines throughout the day, especially after you eat. They signal your pancreas to produce more insulin to process the sugar from your food, and they tell your liver to stop releasing stored sugar into your bloodstream. By blocking the DPP-4 enzyme, Alsita-100 Tablet keeps these helpful incretin hormones active in your body longer, naturally lowering your blood sugar levels only when they are high.
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Alcohol

Caution

It is not known if alcohol interacts with Alsita-100 Tablet . However, avoid/limit alcohol consumption as it might affect blood sugar levels.

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Pregnancy

Caution

Sitagliptin belongs to pregnancy category B. There are no adequate and well-controlled studies in pregnant women. Please consult your doctor if you are pregnant or planning to become pregnant.

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Breast Feeding

Caution

Alsita-100 Tablet should be taken with caution if you are breastfeeding. Please consult your doctor for more information about using Alsita-100 Tablet during lactation.

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Driving

Caution

This medicine may cause dizziness and drowsiness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have liver disease, inform your doctor before taking Alsita-100 Tablet .

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Kidney

Caution

Dose adjustment may be needed in patients with moderate or severe renal insufficiency. Please consult the doctor if you have kidney problems.

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Children

Unsafe

Alsita-100 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established.

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Heart

Safe if prescribed

Alsita-100 Tablet is generally safe for heart patients. Still, it's best to consult your doctor to rule out any interactions with your current medications.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before using Alsita-100 Tablet , as there is limited information available on its safety in this age group.

What if I have taken an overdose of Alsita-100 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose: you may be at higher risk of serious side effects such as a low blood sugar reaction and severe gastrointestinal problems. Seek immediate medical attention if you experience these symptoms.

Diet & Lifestyle Advise

  • Follow a Diabetes-Friendly Diet: Focus on meals rich in high-fibre vegetables, whole grains, and lean proteins while limiting processed sugars and refined carbohydrates.
  • Stay Physically Active: Engage in moderate exercise, such as brisk walking, for at least 30 minutes on most days to help improve insulin sensitivity.
  • Monitor Blood Sugar Regularly: Check your blood sugar levels as directed by your doctor to help ensure your treatment plan is working effectively.
  • Carry a Fast-Acting Sugar Source: Keep fruit juice, glucose tablets, or hard candies readily available in case your blood sugar drops unexpectedly due to changes in diet, activity, or other medicines.

Have a query?

How Soon It Starts Working

The time required for Alsita-100 Tablet to start to work: The time required for Alsita-100 Tablet to show its action is unknown. The time for which the effects of Alsita-100 Tablet last: The duration of action for Alsita-100 Tablet is unknown.

What if you forget to take Alsita-100 Tablet

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one and continue with your regular dosage routine. Avoid taking two doses at once.

Storage

•Store Alsita-100 Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the tablets in their original container to protect them from moisture and direct light.

Drug Warnings

  • Check Before Use: Check your tablet packaging before each use to ensure the medicine is intact and has not expired.
  • Carry Medical Identification: Always carry a medical ID card or wear a bracelet indicating that you have type 2 diabetes and are taking this medication.
  • Watch for Signs of Pancreatitis: Be alert for severe or persistent stomach pain and stop taking the medicine immediately if you suspect symptoms of pancreatic inflammation. Seek medical attention promptly.
  • Monitor Blood Sugar During Illness or Stress: Check your blood sugar levels more closely during periods of illness, fever, physical stress, or before surgery, as your medication requirements may change. Consult your doctor for guidance during these situations.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Alsita-100 Tablet :

  • Insulin and Sulfonylureas: Taking Alsita-100 Tablet with insulin or sulfonylurea medicines, such as glimepiride or glipizide, may increase the risk of low blood sugar. Your doctor may need to adjust your dosage.
  • Digoxin: Alsita-100 Tablet may slightly increase digoxin levels and may require monitoring in some patients. 

Drug-Food Interactions

Certain foods and beverages may affect blood sugar control or increase the risk of side effects while taking Alsita-100 Tablet . Examples include: 

  • Alcohol: Limit or avoid alcohol while taking Alsita-100 Tablet , as it may interfere with blood sugar control and increase the risk of low blood sugar or pancreatitis.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Alsita-100 Tablet , as it may worsen your condition or require closer monitoring.

  • Kidney Disease: Use this medicine with caution if you have kidney disease, as a lower dose may be required.
  • History of Pancreatitis: Avoid or use this medicine cautiously if you have a history of pancreatitis, as it may increase the risk of recurrence.
  • Severe Allergic Reactions: Do not use this medicine if you have previously experienced a severe allergic reaction to Alsita-100 Tablet or any of its ingredients.
SitagliptinGatifloxacin
Critical
SitagliptinIvacaftor
Severe

Drug-Drug Interactions

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SitagliptinGatifloxacin
Critical
How does the drug interact with Alsita-100 Tablet:
Co-administration of Alsita-100 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Taking Alsita-100 Tablet with Gatifloxacin is not recommended as it can lead to a possible interaction, However, it can be taken if advised by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without a doctor's advice.
SitagliptinIvacaftor
Severe
How does the drug interact with Alsita-100 Tablet:
When Alsita-100 Tablet is taken with Ivacaftor, the amount of Alsita-100 Tablet in the blood can go up.

How to manage the interaction:
Taking Alsita-100 Tablet with Ivacaftor together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Alsita-100 Tablet is used to treat type 2 diabetes mellitus. It helps manage blood sugar levels.
Alsita-100 Tablet works by increasing the amount of insulin made by the body. Thus, it helps lower blood glucose levels.
Do not stop taking Alsita-100 Tablet without consulting your doctor, as it may cause an increase in blood glucose levels. Continue taking Alsita-100 Tablet for as long as your doctor has prescribed it to you. Speak with your doctor if you experience any difficulty while taking Alsita-100 Tablet .
Some people taking Alsita-100 Tablet may develop joint pain that could be severe. Consult the doctor if you have severe joint pain.
Alsita-100 Tablet may cause hypoglycaemia (low blood sugar) when taken in combination with other anti-diabetic medications. Talk to the doctor if you experience symptoms of low blood sugar, such as headache, dizziness, sweating, hunger, irritability, confusion, and fast heartbeat.
Eat healthy by including fruits, vegetables and whole grains in your diet. Maintain an active lifestyle by exercising regularly. Manage stress by doing deep breathing or yoga. Avoid smoking and alcohol consumption.
Alsita-100 Tablet should be swallowed as a whole with water; do not crush or chew it.
Alsita-100 Tablet may not cause weight gain. Maintain proper weight by eating healthy food and exercising regularly.
Alsita-100 Tablet may cause kidney problems, sometimes requiring dialysis. The doctor will monitor kidney function before and during treatment with Alsita-100 Tablet .
Alsita-100 Tablet is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Therefore, it is important to stay on the diet and exercise recommended by your doctor while taking Alsita-100 Tablet .
You may experience hypoglycaemia (low blood sugar) if you take more than the prescribed dose of Alsita-100 Tablet . Monitor your blood sugar levels regularly and consult the doctor if you have overdosed.
If you miss a dose of Alsita-100 Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Yes, it is safe to take Alsita-100 Tablet for the long term if prescribed by the doctor.
Alsita-100 Tablet may cause serious side effects like pancreatitis (inflammation of the pancreas), and heart failure. Consult the doctor if you experience severe and persistent pain in the abdomen as it could be a sign of an inflamed pancreas. Seek immediate medical attention if you have signs of heart failure like shortness of breath or trouble breathing, fluid retention, unusually fast increase in weight, and unusual tiredness.
Alsita-100 Tablet may cause side effects such as upper respiratory tract infections, headache, and nasopharyngitis (inflammation of nasal passages). Consult the doctor if any side effects persist or worsen.
Avoid using Alsita-100 Tablet if you are allergic to any of its components. It should not be used in patients with type 1 diabetes, or pancreatitis.
Alsita-100 Tablet may interact with some medicines, hence, let the doctor know if you are taking any other medicines during treatment with Alsita-100 Tablet . Particularly, inform the doctor if you are using insulin, digoxin, furosemide or levothyroxine.
Regular monitoring of blood sugar levels is advised. It is recommended to stay on your prescribed diet and exercise program while taking Alsita-100 Tablet . Consult the doctor if you have stress, fever, trauma, infection or surgery; the doctor may adjust the dose in such cases.
On prolonged use, Alsita-100 Tablet may increase the risk of pancreatitis and kidney problems.
While this medicine rarely causes low blood sugar when used alone, it can happen when combined with other diabetes drugs. Treat low blood sugar immediately with a fast-acting sugar like fruit juice or candy, and talk to your doctor.
Alsita-100 Tablet should be used during pregnancy or breastfeeding only if recommended by your doctor. The safety of this medicine during pregnancy and breastfeeding may not be fully established, so your doctor will assess the benefits and risks before prescribing it.
This medication starts working within a few hours of your first dose to help regulate insulin and blood sugar. However, it may take several weeks of consistent daily use to see a significant improvement in your long-term blood sugar levels (HbA1c). Talk to your doctor if you have questions about your progress.
In rare cases, some people taking this class of medication experience severe and disabling joint pain. If you develop severe joint pain that does not go away, contact your healthcare provider immediately. Talk to your doctor about your symptoms.
Yes, your doctor will likely order regular blood tests to check your long-term blood sugar control (HbA1c) and monitor how well your kidneys are working before and during your treatment. Talk to your doctor to schedule these routine checks.
Yes, but your doctor may need to prescribe a lower dose depending on the severity of your kidney disease. Regular monitoring of kidney function is recommended. Talk to your doctor to ensure you are taking the correct dose for your kidneys.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 021995S019Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Product Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. MedlinePlus. A606023 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  4. Sitagliptin [Prescribing Information]. 2025. [Accessed on 09 Apr. 2025] Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Sitagliptin. [Updated 2019 Feb 7] Check here
  6. Plosker GL. Sitagliptin: A review of its use in patients with type 2 diabetes mellitus. NIH, National Library of Medicine, National Center for Biotechnology Information Pubmed.gov. February 2014. [Accessed on 8th September 2025] Check here
  7. PubChem Compound Summary for CID 4369359, Sitagliptin. National Center for Biotechnology Information. May 2022. [Accessed on 8th September 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ALS0049

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